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Volumn 209, Issue 1, 2012, Pages 187-199

Gfi1b negatively regulates Rag expression directly and via the repression of FoxO1

Author keywords

[No Author keywords available]

Indexed keywords

GROWTH FACTOR INDEPENDENT 1B; RAG1 PROTEIN; TRANSCRIPTION FACTOR; TRANSCRIPTION FACTOR FKHR; UNCLASSIFIED DRUG;

EID: 84856940026     PISSN: 00221007     EISSN: 15409538     Source Type: Journal    
DOI: 10.1084/jem.20110645     Document Type: Article
Times cited : (26)

References (46)
  • 1
    • 44049091757 scopus 로고    scopus 로고
    • Foxo1 directly regulates the transcription of recombination-activating genes during B cell development
    • Amin, R.H., and M.S. Schlissel. 2008. Foxo1 directly regulates the transcription of recombination-activating genes during B cell development. Nat. Immunol. 9:613-622. http://dx.doi.org/10.1038/ni.1612.
    • (2008) Nat. Immunol. , vol.9 , pp. 613-622
    • Amin, R.H.1    Schlissel, M.S.2
  • 2
    • 66849106550 scopus 로고    scopus 로고
    • Paving the way for H2AX phosphorylation: chromatin changes in the DNA damage response
    • Ayoub, N., A.D. Jeyasekharan, J.A. Bernal, and A.R. Venkitaraman. 2009. Paving the way for H2AX phosphorylation: chromatin changes in the DNA damage response. Cell Cycle. 8:1494-1500. http://dx.doi.org/10.4161/cc.8.10.8501.
    • (2009) Cell Cycle , vol.8 , pp. 1494-1500
    • Ayoub, N.1    Jeyasekharan, A.D.2    Bernal, J.A.3    Venkitaraman, A.R.4
  • 4
    • 37549065849 scopus 로고    scopus 로고
    • Chromosomal position of a VH gene segment determines its activation and inactivation as a substrate for V(D)J recombination
    • Bates, J.G., D. Cado, H. Nolla, and M.S. Schlissel. 2007. Chromosomal position of a VH gene segment determines its activation and inactivation as a substrate for V(D)J recombination. J. Exp. Med. 204:3247-3256. http://dx.doi.org/10.1084/jem.20071787.
    • (2007) J. Exp. Med. , vol.204 , pp. 3247-3256
    • Bates, J.G.1    Cado, D.2    Nolla, H.3    Schlissel, M.S.4
  • 8
    • 70349592855 scopus 로고    scopus 로고
    • Histone modifications during DNA replication
    • Falbo, K.B., and X. Shen. 2009. Histone modifications during DNA replication. Mol. Cells. 28:149-154. http://dx.doi.org/10.1007/s10059-009-0127-7.
    • (2009) Mol. Cells. , vol.28 , pp. 149-154
    • Falbo, K.B.1    Shen, X.2
  • 9
    • 33645766023 scopus 로고    scopus 로고
    • Gfi1 and Gfi1b act equivalently in haematopoiesis, but have distinct, non-overlapping functions in inner ear development
    • Fiolka, K., R. Hertzano, L. Vassen, H. Zeng, O. Hermesh, K.B. Avraham, U. Dührsen, and T. Möröy. 2006. Gfi1 and Gfi1b act equivalently in haematopoiesis, but have distinct, non-overlapping functions in inner ear development. EMBO Rep. 7:326-333. http://dx.doi.org/10.1038/sj.embor.7400618.
    • (2006) EMBO Rep , vol.7 , pp. 326-333
    • Fiolka, K.1    Hertzano, R.2    Vassen, L.3    Zeng, H.4    Hermesh, O.5    Avraham, K.B.6    Dührsen, U.7    Möröy, T.8
  • 10
    • 33748144349 scopus 로고    scopus 로고
    • Pathways that suppress programmed DNA breaks from progressing to chromosomal breaks and translocations
    • Franco, S., F.W. Alt, and J.P. Manis. 2006. Pathways that suppress programmed DNA breaks from progressing to chromosomal breaks and translocations. DNA Repair (Amst.). 5:1030-1041. http://dx.doi.org/10.1016/j.dnarep.2006.05.024.
    • (2006) DNA Repair (Amst.). , vol.5 , pp. 1030-1041
    • Franco, S.1    Alt, F.W.2    Manis, J.P.3
  • 11
    • 24344466882 scopus 로고    scopus 로고
    • DNA methylation and histone modifications: teaming up to silence genes
    • Fuks, F. 2005. DNA methylation and histone modifications: teaming up to silence genes. Curr. Opin. Genet. Dev. 15:490-495. http://dx.doi.org/10.1016/j.gde.2005.08.002.
    • (2005) Curr. Opin. Genet. Dev. , vol.15 , pp. 490-495
    • Fuks, F.1
  • 12
    • 0037146798 scopus 로고    scopus 로고
    • Immunoblotting and sequential lysis protocols for the analysis of tyrosine phosphorylation-dependent signaling
    • Gilbert, C., E. Rollet-Labelle, A.C. Caon, and P.H. Naccache. 2002. Immunoblotting and sequential lysis protocols for the analysis of tyrosine phosphorylation-dependent signaling. J. Immunol. Methods. 271:185-201. http://dx.doi.org/10.1016/S0022-1759(02)00347-2.
    • (2002) J. Immunol. Methods. , vol.271 , pp. 185-201
    • Gilbert, C.1    Rollet-Labelle, E.2    Caon, A.C.3    Naccache, P.H.4
  • 13
    • 0029806268 scopus 로고    scopus 로고
    • The Gfi-1 proto-oncoprotein contains a novel transcriptional repressor domain, SNAG, and inhibits G1 arrest induced by interleukin-2 withdrawal
    • Grimes, H.L., T.O. Chan, P.A. Zweidler-McKay, B. Tong, and P.N. Tsichlis. 1996. The Gfi-1 proto-oncoprotein contains a novel transcriptional repressor domain, SNAG, and inhibits G1 arrest induced by interleukin-2 withdrawal. Mol. Cell. Biol. 16:6263-6272.
    • (1996) Mol. Cell. Biol. , vol.16 , pp. 6263-6272
    • Grimes, H.L.1    Chan, T.O.2    Zweidler-McKay, P.A.3    Tong, B.4    Tsichlis, P.N.5
  • 15
    • 0038783576 scopus 로고    scopus 로고
    • A conserved transcriptional enhancer regulates RAG gene expression in developing B cells
    • Hsu, L.Y., J. Lauring, H.E. Liang, S. Greenbaum, D. Cado, Y. Zhuang, and M.S. Schlissel. 2003. A conserved transcriptional enhancer regulates RAG gene expression in developing B cells. Immunity. 19:105-117. http://dx.doi.org/10.1016/S1074-7613(03)00181-X.
    • (2003) Immunity , vol.19 , pp. 105-117
    • Hsu, L.Y.1    Lauring, J.2    Liang, H.E.3    Greenbaum, S.4    Cado, D.5    Zhuang, Y.6    Schlissel, M.S.7
  • 16
    • 33746150775 scopus 로고    scopus 로고
    • Foxp1 is an essential transcriptional regulator of B cell development
    • Hu, H., B. Wang, M. Borde, J. Nardone, S. Maika, L. Allred, P.W. Tucker, and A. Rao. 2006. Foxp1 is an essential transcriptional regulator of B cell development. Nat. Immunol. 7:819-826. http://dx.doi.org/10.1038/ni1358.
    • (2006) Nat. Immunol. , vol.7 , pp. 819-826
    • Hu, H.1    Wang, B.2    Borde, M.3    Nardone, J.4    Maika, S.5    Allred, L.6    Tucker, P.W.7    Rao, A.8
  • 17
    • 24944569193 scopus 로고    scopus 로고
    • GATA-1 mediates autoregulation of Gfi-1B transcription in K562 cells
    • Huang, D.Y., Y.Y. Kuo, and Z.F. Chang. 2005. GATA-1 mediates autoregulation of Gfi-1B transcription in K562 cells. Nucleic Acids Res. 33:5331-5342. http://dx.doi.org/10.1093/nar/gki838.
    • (2005) Nucleic Acids Res , vol.33 , pp. 5331-5342
    • Huang, D.Y.1    Kuo, Y.Y.2    Chang, Z.F.3
  • 19
    • 0032740593 scopus 로고    scopus 로고
    • Cutting edge: absence of expression of RAG1 in peritoneal B-1 cells detected by knocking into RAG1 locus with green fluorescent protein gene
    • Kuwata, N., H. Igarashi, T. Ohmura, S. Aizawa, and N. Sakaguchi. 1999. Cutting edge: absence of expression of RAG1 in peritoneal B-1 cells detected by knocking into RAG1 locus with green fluorescent protein gene. J. Immunol. 163:6355-6359.
    • (1999) J. Immunol. , vol.163 , pp. 6355-6359
    • Kuwata, N.1    Igarashi, H.2    Ohmura, T.3    Aizawa, S.4    Sakaguchi, N.5
  • 20
    • 33747196725 scopus 로고    scopus 로고
    • Multilineage transcriptional priming and determination of alternate hematopoietic cell fates
    • Laslo, P., C.J. Spooner, A. Warmflash, D.W. Lancki, H.J. Lee, R. Sciammas, B.N. Gantner, A.R. Dinner, and H. Singh. 2006. Multilineage transcriptional priming and determination of alternate hematopoietic cell fates. Cell. 126:755-766. http://dx.doi.org/10.1016/j.cell.2006.06.052.
    • (2006) Cell , vol.126 , pp. 755-766
    • Laslo, P.1    Spooner, C.J.2    Warmflash, A.3    Lancki, D.W.4    Lee, H.J.5    Sciammas, R.6    Gantner, B.N.7    Dinner, A.R.8    Singh, H.9
  • 21
    • 70349850505 scopus 로고    scopus 로고
    • Gfi-1B promoter remains associated with active chromatin marks throughout erythroid differentiation of human primary progenitor cells
    • Laurent, B., V. Randrianarison-Huetz, Z. Kadri, P.H. Roméo, F. Porteu, and D. Duménil. 2009. Gfi-1B promoter remains associated with active chromatin marks throughout erythroid differentiation of human primary progenitor cells. Stem Cells. 27:2153-2162. http://dx.doi.org/10.1002/stem.151.
    • (2009) Stem Cells , vol.27 , pp. 2153-2162
    • Laurent, B.1    Randrianarison-Huetz, V.2    Kadri, Z.3    Roméo, P.H.4    Porteu, F.5    Duménil, D.6
  • 22
    • 77950022648 scopus 로고    scopus 로고
    • Solution structure of Gfi-1 zinc domain bound to consensus DNA
    • Lee, S., K. Doddapaneni, A. Hogue, L. McGhee, S. Meyers, and Z. Wu. 2010. Solution structure of Gfi-1 zinc domain bound to consensus DNA. J. Mol. Biol. 397:1055-1066. http://dx.doi.org/10.1016/j.jmb.2010.02.006.
    • (2010) J. Mol. Biol. , vol.397 , pp. 1055-1066
    • Lee, S.1    Doddapaneni, K.2    Hogue, A.3    McGhee, L.4    Meyers, S.5    Wu, Z.6
  • 23
    • 0029164598 scopus 로고
    • Conditional site-specific recombination in mammalian cells using a ligand-dependent chimeric Cre recombinase
    • Metzger, D., J. Clifford, H. Chiba, and P. Chambon. 1995. Conditional site-specific recombination in mammalian cells using a ligand-dependent chimeric Cre recombinase. Proc. Natl. Acad. Sci. USA. 92:6991-6995. http://dx.doi.org/10.1073/pnas.92.15.6991.
    • (1995) Proc. Natl. Acad. Sci. USA. , vol.92 , pp. 6991-6995
    • Metzger, D.1    Clifford, J.2    Chiba, H.3    Chambon, P.4
  • 25
    • 0037232230 scopus 로고    scopus 로고
    • A small molecule Abl kinase inhibitor induces differentiation of Abelson virus-transformed pre-B cell lines
    • Muljo, S.A., and M.S. Schlissel. 2003. A small molecule Abl kinase inhibitor induces differentiation of Abelson virus-transformed pre-B cell lines. Nat. Immunol. 4:31-37. http://dx.doi.org/10.1038/ni870.
    • (2003) Nat. Immunol. , vol.4 , pp. 31-37
    • Muljo, S.A.1    Schlissel, M.S.2
  • 26
    • 36148979478 scopus 로고    scopus 로고
    • Transcriptional repressor Gfi1 integrates cytokine-receptor signals controlling B-cell differentiation
    • Rathinam, C., and C. Klein. 2007. Transcriptional repressor Gfi1 integrates cytokine-receptor signals controlling B-cell differentiation. PLoS ONE. 2:e306. http://dx.doi.org/10.1371/journal.pone.0000306.
    • (2007) PLoS ONE , vol.2
    • Rathinam, C.1    Klein, C.2
  • 27
    • 0006301124 scopus 로고
    • In vitro transformation of lymphoid cells by Abelson murine leukemia virus
    • Rosenberg, N., D. Baltimore, and C.D. Scher. 1975. In vitro transformation of lymphoid cells by Abelson murine leukemia virus. Proc. Natl. Acad. Sci. USA. 72:1932-1936. http://dx.doi.org/10.1073/pnas.72.5.1932.
    • (1975) Proc. Natl. Acad. Sci. USA. , vol.72 , pp. 1932-1936
    • Rosenberg, N.1    Baltimore, D.2    Scher, C.D.3
  • 28
    • 0036467868 scopus 로고    scopus 로고
    • The zinc-finger protooncogene Gfi-1b is essential for development of the erythroid and megakaryocytic lineages
    • Saleque, S., S. Cameron, and S.H. Orkin. 2002. The zinc-finger protooncogene Gfi-1b is essential for development of the erythroid and megakaryocytic lineages. Genes Dev. 16:301-306. http://dx.doi.org/10.1101/gad.959102.
    • (2002) Genes Dev , vol.16 , pp. 301-306
    • Saleque, S.1    Cameron, S.2    Orkin, S.H.3
  • 29
    • 34547785073 scopus 로고    scopus 로고
    • Epigenetic regulation of hematopoietic differentiation by Gfi-1 and Gfi-1b is mediated by the cofactors CoREST and LSD1
    • Saleque, S., J. Kim, H.M. Rooke, and S.H. Orkin. 2007. Epigenetic regulation of hematopoietic differentiation by Gfi-1 and Gfi-1b is mediated by the cofactors CoREST and LSD1. Mol. Cell. 27:562-572. http://dx.doi.org/10.1016/j.molcel.2007.06.039.
    • (2007) Mol. Cell. , vol.27 , pp. 562-572
    • Saleque, S.1    Kim, J.2    Rooke, H.M.3    Orkin, S.H.4
  • 30
    • 0242468050 scopus 로고    scopus 로고
    • Regulating antigen-receptor gene assembly
    • Schlissel, M.S. 2003. Regulating antigen-receptor gene assembly. Nat. Rev. Immunol. 3:890-899. http://dx.doi.org/10.1038/nri1225.
    • (2003) Nat. Rev. Immunol. , vol.3 , pp. 890-899
    • Schlissel, M.S.1
  • 31
    • 0027769386 scopus 로고
    • Double-strand signal sequence breaks in V(D)J recombination are blunt, 5'-phosphorylated, RAG-dependent, and cell cycle regulated
    • Schlissel, M., A. Constantinescu, T. Morrow, M. Baxter, and A. Peng. 1993. Double-strand signal sequence breaks in V(D)J recombination are blunt, 5'-phosphorylated, RAG-dependent, and cell cycle regulated. Genes Dev. 7:2520-2532. http://dx.doi.org/10.1101/gad.7.12b.2520.
    • (1993) Genes Dev , vol.7 , pp. 2520-2532
    • Schlissel, M.1    Constantinescu, A.2    Morrow, T.3    Baxter, M.4    Peng, A.5
  • 32
    • 33745121244 scopus 로고    scopus 로고
    • Leukemia and lymphoma: a cost of doingbusiness for adaptive immunity
    • Schlissel, M.S., C.R. Kaffer, and J.D. Curry. 2006. Leukemia and lymphoma: a cost of doing business for adaptive immunity. Genes Dev. 20: 1539-1544. http://dx.doi.org/10.1101/gad.1446506.
    • (2006) Genes Dev , vol.20 , pp. 1539-1544
    • Schlissel, M.S.1    Kaffer, C.R.2    Curry, J.D.3
  • 33
    • 79251558438 scopus 로고    scopus 로고
    • Receptor editing as a mechanism of B cell tolerance
    • Sukumar, S., and M.S. Schlissel. 2011. Receptor editing as a mechanism of B cell tolerance. J. Immunol. 186:1301-1302. http://dx.doi.org/10.4049/jimmunol.1090129.
    • (2011) J. Immunol. , vol.186 , pp. 1301-1302
    • Sukumar, S.1    Schlissel, M.S.2
  • 34
    • 0020534965 scopus 로고
    • Somatic generation of antibody diversity
    • Tonegawa, S. 1983. Somatic generation of antibody diversity. Nature. 302: 575-581. http://dx.doi.org/10.1038/302575a0.
    • (1983) Nature , vol.302 , pp. 575-581
    • Tonegawa, S.1
  • 35
    • 78149471436 scopus 로고    scopus 로고
    • Gfi1 and Gfi1b: key regulators of hematopoiesis
    • van der Meer, L.T., J.H. Jansen, and B.A. van der Reijden. 2010. Gfi1 and Gfi1b: key regulators of hematopoiesis. Leukemia. 24:1834-1843. http://dx.doi.org/10.1038/leu.2010.195.
    • (2010) Leukemia , vol.24 , pp. 1834-1843
    • van der Meer, L.T.1    Jansen, J.H.2    van der Reijden, B.A.3
  • 36
    • 14244258985 scopus 로고    scopus 로고
    • Direct transcriptional repression of the genes encoding the zinc-finger proteins Gfi1b and Gfi1 by Gfi1b
    • Vassen, L., K. Fiolka, S. Mahlmann, and T. Möröy. 2005. Direct transcriptional repression of the genes encoding the zinc-finger proteins Gfi1b and Gfi1 by Gfi1b. Nucleic Acids Res. 33:987-998. http://dx.doi.org/10.1093/nar/gki243.
    • (2005) Nucleic Acids Res , vol.33 , pp. 987-998
    • Vassen, L.1    Fiolka, K.2    Mahlmann, S.3    Möröy, T.4
  • 37
    • 33745756792 scopus 로고    scopus 로고
    • Gfi1b alters histone methylation at target gene promoters and sites of gamma-satellite containing heterochromatin
    • Vassen, L., K. Fiolka, and T. Möröy. 2006. Gfi1b alters histone methylation at target gene promoters and sites of gamma-satellite containing heterochromatin. EMBO J. 25:2409-2419. http://dx.doi.org/10.1038/ sj.emboj.7601124.
    • (2006) EMBO J , vol.25 , pp. 2409-2419
    • Vassen, L.1    Fiolka, K.2    Möröy, T.3
  • 38
    • 33947251378 scopus 로고    scopus 로고
    • Gfi1b:green fluorescent protein knock-in mice reveal a dynamic expression pattern of Gfi1b during hematopoiesis that is largely complementary to Gfi1
    • Vassen, L., T. Okayama, and T. Möröy. 2007. Gfi1b:green fluorescent protein knock-in mice reveal a dynamic expression pattern of Gfi1b during hematopoiesis that is largely complementary to Gfi1. Blood. 109:2356-2364. http://dx.doi.org/10.1182/blood-2006-06-030031.
    • (2007) Blood , vol.109 , pp. 2356-2364
    • Vassen, L.1    Okayama, T.2    Möröy, T.3
  • 42
    • 0033551866 scopus 로고    scopus 로고
    • Coordinate regulation of RAG1 and RAG2 by cell type-specific DNA elements 5' of RAG2
    • Yu, W., Z. Misulovin, H. Suh, R.R. Hardy, M. Jankovic, N. Yannoutsos, and M.C. Nussenzweig. 1999. Coordinate regulation of RAG1 and RAG2 by cell type-specific DNA elements 5' of RAG2. Science. 285:1080-1084. http://dx.doi.org/10.1126/science.285.5430.1080.
    • (1999) Science , vol.285 , pp. 1080-1084
    • Yu, W.1    Misulovin, Z.2    Suh, H.3    Hardy, R.R.4    Jankovic, M.5    Yannoutsos, N.6    Nussenzweig, M.C.7
  • 43
    • 0034073382 scopus 로고    scopus 로고
    • Transcriptional repression by blimp-1 (PRDI-BF1) involves recruitment of histone deacetylase
    • Yu, J., C. Angelin-Duclos, J. Greenwood, J. Liao, and K. Calame. 2000. Transcriptional repression by blimp-1 (PRDI-BF1) involves recruitment of histone deacetylase. Mol. Cell. Biol. 20:2592-2603. http://dx.doi.org/10.1128/MCB.20.7.2592-2603.2000.
    • (2000) Mol. Cell. Biol. , vol.20 , pp. 2592-2603
    • Yu, J.1    Angelin-Duclos, C.2    Greenwood, J.3    Liao, J.4    Calame, K.5
  • 44
    • 4644272644 scopus 로고    scopus 로고
    • Gfi1:green fluorescent protein knock-in mutant reveals differential expression and autoregulation of the growth factor independence 1 (Gfi1) gene during lymphocyte development
    • Yücel, R., C. Kosan, F. Heyd, and T. Möröy. 2004. Gfi1:green fluorescent protein knock-in mutant reveals differential expression and autoregulation of the growth factor independence 1 (Gfi1) gene during lymphocyte development. J. Biol. Chem. 279:40906-40917. http://dx.doi.org/10.1074/jbc.M400808200.
    • (2004) J. Biol. Chem. , vol.279 , pp. 40906-40917
    • Yücel, R.1    Kosan, C.2    Heyd, F.3    Möröy, T.4
  • 45
    • 8144220648 scopus 로고    scopus 로고
    • Transcription factor Gfi1 regulates self-renewal and engraftment of hematopoietic stem cells
    • Zeng, H., R. Yücel, C. Kosan, L. Klein-Hitpass, and T. Möröy. 2004. Transcription factor Gfi1 regulates self-renewal and engraftment of hematopoietic stem cells. EMBO J. 23:4116-4125. http://dx.doi.org/10.1038/sj.emboj.7600419.
    • (2004) EMBO J , vol.23 , pp. 4116-4125
    • Zeng, H.1    Yücel, R.2    Kosan, C.3    Klein-Hitpass, L.4    Möröy, T.5
  • 46
    • 0029897536 scopus 로고    scopus 로고
    • Gfi-1 encodes a nuclear zinc finger protein that binds DNA and functions as a transcriptional repressor
    • Zweidler-Mckay, P.A., H.L. Grimes, M.M. Flubacher, and P.N. Tsichlis. 1996. Gfi-1 encodes a nuclear zinc finger protein that binds DNA and functions as a transcriptional repressor. Mol. Cell. Biol. 16: 4024-4034.
    • (1996) Mol. Cell. Biol. , vol.16 , pp. 4024-4034
    • Zweidler-Mckay, P.A.1    Grimes, H.L.2    Flubacher, M.M.3    Tsichlis, P.N.4


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