γ-aminobutyric acid type A receptor modulation by etomidate analogs

Anesthesiology

Volumn 124, Issue 3, 2016, Pages 651-663

  Pejo, Ervin ^a   Santer, Peter ^a   Wang, Lei ^b   Dershwitz, Philip ^a   Husain, S Shaukat ^a   Raines, Douglas E ^a  

^a MASSACHUSETTS GENERAL HOSPITAL   (United States)

^b CERTARA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

4 AMINOBUTYRIC ACID A RECEPTOR; 4 AMINOBUTYRIC ACID A RECEPTOR ALPHA1; 4 AMINOBUTYRIC ACID A RECEPTOR BETA3; 4 AMINOBUTYRIC ACID A RECEPTOR GAMMA2; 4 PYRIDINE CARBOETOMIDATE; ANESTHETIC AGENT; CARBOETOMIDATE; CYCLOPROPYL ETOMIDATE; CYCLOPROPYLMETHOXYCARBONYL METOMIDATE; DIHYDROGEN ETOMIDATE; DIMETHYLMETHOXYCARBONYL ETOMIDATE; DIMETHYLMETHOXYCARBONYL METOMIDATE; ETOMIDATE; ETOMIDATE DERIVATIVE; ISOPROPYLMETHOXYCARBONYL METOMIDATE; METHOXYCARBONYL ETOMIDATE; METHOXYCARBONYL METOMIDATE; METHYLMETHOXYCARBONYL ETOMIDATE; METHYLMETHOXYCARBONYL METOMIDATE; METOMIDATE; PENTAFLUOROETOMIDATE; UNCLASSIFIED DRUG; BENZODIAZEPINE RECEPTOR AFFECTING AGENT; HYPNOTIC SEDATIVE AGENT;

ADULT; ANIMAL EXPERIMENT; ARTICLE; COMPARATIVE MOLECULAR FIELD ANALYSIS; COMPUTER MODEL; CONCENTRATION RESPONSE; CONTROLLED STUDY; CORRELATION ANALYSIS; DRUG BINDING SITE; DRUG POTENCY; DRUG STRUCTURE; ELECTROPHYSIOLOGY; GENE MUTATION; HYDROPHOBICITY; HYPNOSIS; MALE; MATHEMATICAL ANALYSIS; MOLECULAR MODEL; NONHUMAN; PHARMACOPHORE; PRIORITY JOURNAL; QUANTITATIVE STRUCTURE ACTIVITY RELATION; RAT; RIGHTING REFLEX; STATISTICAL MODEL; STATISTICAL SIGNIFICANCE; VOLTAGE CLAMP TECHNIQUE; ANALOGS AND DERIVATIVES; ANIMAL; DOSE RESPONSE; FEMALE; PHYSIOLOGY; SPRAGUE DAWLEY RAT; XENOPUS LAEVIS;

ANIMALS; DOSE-RESPONSE RELATIONSHIP, DRUG; ETOMIDATE; FEMALE; GABA MODULATORS; HYPNOTICS AND SEDATIVES; RATS; RATS, SPRAGUE-DAWLEY; RECEPTORS, GABA-A; XENOPUS LAEVIS;

EID: 84951310883     PISSN: 00033022     EISSN: 15281175     Source Type: Journal    
DOI: 10.1097/ALN.0000000000000992     Document Type: Article

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