Carboetomidate: An analog of etomidate that interacts weakly with 11β-hydroxylase

Anesthesia and Analgesia

Volumn 116, Issue 6, 2013, Pages 1249-1256

  Shanmugasundararaj, Sivananthaperumal ^a   Zhou, Xiaojuan ^a   Neunzig, Jens ^b   Bernhardt, Rita ^b   Cotten, Joseph F ^a   Ge, Rile ^a   Miller, Keith W ^a   Raines, Douglas E ^a  

^a MASSACHUSETTS GENERAL HOSPITAL   (United States)

^b SAARLAND UNIVERSITY   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

AZIETOMIDATE; CARBOETOMIDATE; CARBONYL DERIVATIVE; DRUG ANALOG; ETOMIDATE; HEME; HEMOPROTEIN; HYDROCORTISONE; IRON; OXYGEN; PHENYL GROUP; PHENYLALANINE; STEROID 11BETA MONOOXYGENASE; TRITIUM; UNCLASSIFIED DRUG;

ARTICLE; BINDING AFFINITY; CHEMICAL INTERACTION; COMPUTER MODEL; COMPUTER PROGRAM; CONCENTRATION RESPONSE; CONTROLLED STUDY; DRUG ABSORPTION; DRUG BINDING; DRUG SELECTIVITY; DRUG STRUCTURE; ENZYME ACTIVE SITE; ENZYME INHIBITION; HORMONE SYNTHESIS; HUMAN; HUMAN CELL; LIGAND BINDING; MOLECULAR MODEL; PHOTOAFFINITY LABELING; PRIORITY JOURNAL; SPECTROSCOPY;

BINDING SITES; ETOMIDATE; HEME; HUMANS; HYDROCORTISONE; PYRROLES; STEROID 11-BETA-HYDROXYLASE;

EID: 84878390256     PISSN: 00032999     EISSN: 15267598     Source Type: Journal    
DOI: 10.1213/ANE.0b013e31828b3637     Document Type: Article

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