메뉴 건너뛰기




Volumn 122, Issue 4, 2015, Pages 787-794

Structural comparisons of ligand-gated ion channels in open, closed, and desensitized states identify a novel propofol-binding site on mammalian γ-aminobutyric acid type A receptors

Author keywords

[No Author keywords available]

Indexed keywords

4 AMINOBUTYRIC ACID A RECEPTOR; AMINO ACID; LIGAND GATED ION CHANNEL; PROPOFOL; INTRAVENOUS ANESTHETIC AGENT;

EID: 84932123482     PISSN: 00033022     EISSN: 15281175     Source Type: Journal    
DOI: 10.1097/ALN.0000000000000588     Document Type: Article
Times cited : (28)

References (38)
  • 1
    • 0025986811 scopus 로고
    • The actions of propofol on inhibitory amino acid receptors of bovine adrenomedullary chromaffin cells and rodent central neurones
    • Hales TG, Lambert JJ: The actions of propofol on inhibitory amino acid receptors of bovine adrenomedullary chromaffin cells and rodent central neurones. Br J Pharmacol 1991; 104:619-28
    • (1991) Br J Pharmacol , vol.104 , pp. 619-628
    • Hales, T.G.1    Lambert, J.J.2
  • 2
    • 0019301241 scopus 로고
    • Barbiturate receptor sites are coupled to benzodiazepine receptors
    • Leeb-Lundberg F, Snowman A, Olsen RW: Barbiturate receptor sites are coupled to benzodiazepine receptors. Proc Natl Acad Sci USA 1980; 77:7468-72
    • (1980) Proc Natl Acad Sci USA , vol.77 , pp. 7468-7472
    • Leeb-Lundberg, F.1    Snowman, A.2    Olsen, R.W.3
  • 3
    • 0018140477 scopus 로고
    • Different actions of anticonvulsant and anesthetic barbiturates revealed by use of cultured mammalian neurons
    • Macdonald RL, Barker JL: Different actions of anticonvulsant and anesthetic barbiturates revealed by use of cultured mammalian neurons. Science 1978; 200:775-7
    • (1978) Science , vol.200 , pp. 775-777
    • MacDonald, R.L.1    Barker, J.L.2
  • 4
    • 0017796829 scopus 로고
    • Pentobarbital: Differential postsynaptic actions on sympathetic ganglion cells
    • Nicoll RA: Pentobarbital: Differential postsynaptic actions on sympathetic ganglion cells. Science 1978; 199:451-2
    • (1978) Science , vol.199 , pp. 451-452
    • Nicoll, R.A.1
  • 5
    • 0023008748 scopus 로고
    • Facilitatory action of etomidate and pentobarbital on recurrent inhibition in rat hippocampal pyramidal neurons
    • Proctor WR, Mynlieff M, Dunwiddie TV: Facilitatory action of etomidate and pentobarbital on recurrent inhibition in rat hippocampal pyramidal neurons. J Neurosci 1986; 6:3161-8
    • (1986) J Neurosci , vol.6 , pp. 3161-3168
    • Proctor, W.R.1    Mynlieff, M.2    Dunwiddie, T.V.3
  • 6
    • 30444459043 scopus 로고    scopus 로고
    • Molecular targets underlying general anaesthesia
    • Franks NP: Molecular targets underlying general anaesthesia. Br J Pharmacol 2006; 147(suppl 1):S72-81
    • (2006) Br J Pharmacol , vol.147 , pp. S72-81
    • Franks, N.P.1
  • 7
    • 42349089480 scopus 로고    scopus 로고
    • General anaesthesia: From molecular targets to neuronal pathways of sleep and arousal
    • Franks NP: General anaesthesia: From molecular targets to neuronal pathways of sleep and arousal. Nat Rev Neurosci 2008; 9:370-86
    • (2008) Nat Rev Neurosci , vol.9 , pp. 370-386
    • Franks, N.P.1
  • 8
    • 4344574333 scopus 로고    scopus 로고
    • Molecular and neuronal substrates for general anaesthetics
    • Rudolph U, Antkowiak B: Molecular and neuronal substrates for general anaesthetics. Nat Rev Neurosci 2004; 5:709-20
    • (2004) Nat Rev Neurosci , vol.5 , pp. 709-720
    • Rudolph, U.1    Antkowiak, B.2
  • 9
    • 1642495618 scopus 로고    scopus 로고
    • Defining the propofol binding site location on the GABAA receptor
    • Bali M, Akabas MH: Defining the propofol binding site location on the GABAA receptor. Mol Pharmacol 2004; 65:68-76
    • (2004) Mol Pharmacol , vol.65 , pp. 68-76
    • Bali, M.1    Akabas, M.H.2
  • 10
    • 77950557636 scopus 로고    scopus 로고
    • Numerous classes of general anesthetics inhibit etomidate binding to gammaaminobutyric acid type A (GABAA) receptors
    • Li GD, Chiara DC, Cohen JB, Olsen RW: Numerous classes of general anesthetics inhibit etomidate binding to gammaaminobutyric acid type A (GABAA) receptors. J Biol Chem 2010; 285:8615-20
    • (2010) J Biol Chem , vol.285 , pp. 8615-8620
    • Li, G.D.1    Chiara, D.C.2    Cohen, J.B.3    Olsen, R.W.4
  • 11
    • 84888298803 scopus 로고    scopus 로고
    • Assessment of homology templates and an anesthetic binding site within the-aminobutyric acid receptor
    • Bertaccini EJ, Yoluk O, Lindahl ER, Trudell JR: Assessment of homology templates and an anesthetic binding site within the-aminobutyric acid receptor. Anesthes iology 2013; 119:1087-95
    • (2013) Anesthes Iology , vol.119 , pp. 1087-1095
    • Bertaccini, E.J.1    Yoluk, O.2    Lindahl, E.R.3    Trudell, J.R.4
  • 12
    • 33751119897 scopus 로고    scopus 로고
    • Identification of a GABAA receptor anesthetic binding site at subunit interfaces by photolabeling with an etomidate analog
    • Li GD, Chiara DC, Sawyer GW, Husain SS, Olsen RW, Cohen JB: Identification of a GABAA receptor anesthetic binding site at subunit interfaces by photolabeling with an etomidate analog. J Neurosci 2006; 26:11599-605
    • (2006) J Neurosci , vol.26 , pp. 11599-11605
    • Li, G.D.1    Chiara, D.C.2    Sawyer, G.W.3    Husain, S.S.4    Olsen, R.W.5    Cohen, J.B.6
  • 16
    • 0021920994 scopus 로고
    • The firefly throws light on anesthesia
    • Franks NP, Lieb WR: The firefly throws light on anesthesia. Chemistry in Britain 1985; 21:919-21
    • (1985) Chemistry in Britain , vol.21 , pp. 919-921
    • Franks, N.P.1    Lieb, W.R.2
  • 17
    • 84887444038 scopus 로고    scopus 로고
    • Gating of the proton-gated ion channel from Gloeobacter violaceus at pH 4 as revealed by X-ray crystallography
    • Gonzalez-Gutierrez G, Cuello LG, Nair SK, Grosman C: Gating of the proton-gated ion channel from Gloeobacter violaceus at pH 4 as revealed by X-ray crystallography. Proc Natl Acad Sci USA 2013; 110:18716-21
    • (2013) Proc Natl Acad Sci USA , vol.110 , pp. 18716-18721
    • Gonzalez-Gutierrez, G.1    Cuello, L.G.2    Nair, S.K.3    Grosman, C.4
  • 19
    • 84906568725 scopus 로고    scopus 로고
    • X-ray structures of GluCl in apo states reveal a gating mechanism of Cys-loop receptors
    • Althoff T, Hibbs RE, Banerjee S, Gouaux E: X-ray structures of GluCl in apo states reveal a gating mechanism of Cys-loop receptors. Nature 2014; 512:333-7
    • (2014) Nature , vol.512 , pp. 333-337
    • Althoff, T.1    Hibbs, R.E.2    Banerjee, S.3    Gouaux, E.4
  • 20
    • 79957953215 scopus 로고    scopus 로고
    • Principles of activation and permeation in an anion-selective Cys-loop receptor
    • Hibbs RE, Gouaux E: Principles of activation and permeation in an anion-selective Cys-loop receptor. Nature 2011; 474:54-60
    • (2011) Nature , vol.474 , pp. 54-60
    • Hibbs, R.E.1    Gouaux, E.2
  • 21
    • 84905669878 scopus 로고    scopus 로고
    • Crystal structure of a human GABAA receptor
    • Miller PS, Aricescu AR: Crystal structure of a human GABAA receptor. Nature 2014; 512:270-5
    • (2014) Nature , vol.512 , pp. 270-275
    • Miller, P.S.1    Aricescu, A.R.2
  • 23
    • 76149120388 scopus 로고    scopus 로고
    • AutoDock Vina: Improving the speed and accuracy of docking with a new scoring function, efficient optimization, and multithreading
    • Trott O, Olson AJ: AutoDock Vina: Improving the speed and accuracy of docking with a new scoring function, efficient optimization, and multithreading. J Comput Chem 2010; 31:455-61
    • (2010) J Comput Chem , vol.31 , pp. 455-461
    • Trott, O.1    Olson, A.J.2
  • 26
    • 0034624021 scopus 로고    scopus 로고
    • Binding of the general anesthetics propofol and halothane to human serum albumin. High resolution crystal structures
    • Bhattacharya AA, Curry S, Franks NP: Binding of the general anesthetics propofol and halothane to human serum albumin. High resolution crystal structures. J Biol Chem 2000; 275:38731-8
    • (2000) J Biol Chem , vol.275 , pp. 38731-38738
    • Bhattacharya, A.A.1    Curry, S.2    Franks, N.P.3
  • 27
    • 0020394696 scopus 로고
    • Molecular mechanisms of general anaesthesia
    • Franks NP, Lieb WR: Molecular mechanisms of general anaesthesia. Nature 1982; 300:487-93
    • (1982) Nature , vol.300 , pp. 487-493
    • Franks, N.P.1    Lieb, W.R.2
  • 28
    • 78651189765 scopus 로고
    • On the nature of allosteric transitions: A plausible model
    • Monod J, Wyman J, Changeux JP: On the nature of allosteric transitions: A plausible model. J Mol Biol 1965; 12:88-118
    • (1965) J Mol Biol , vol.12 , pp. 88-118
    • Monod, J.1    Wyman, J.2    Changeux, J.P.3
  • 29
    • 2442687767 scopus 로고    scopus 로고
    • Gating allosterism at a single class of etomidate sites on 122L GABAA receptors accounts for both direct activation and agonist modulation
    • Rusch D, Zhong H, Forman SA: Gating allosterism at a single class of etomidate sites on 122L GABAA receptors accounts for both direct activation and agonist modulation. J Biol Chem 2004; 279:20982-92
    • (2004) J Biol Chem , vol.279 , pp. 20982-20992
    • Rusch, D.1    Zhong, H.2    Forman, S.A.3
  • 30
    • 0028889722 scopus 로고
    • The effects of temperature on the interactions between volatile general anaesthetics and a neuronal nicotinic acetylcholine receptor
    • Dickinson R, Lieb WR, Franks NP: The effects of temperature on the interactions between volatile general anaesthetics and a neuronal nicotinic acetylcholine receptor. Br J Pharmacol 1995; 116:2949-56
    • (1995) Br J Pharmacol , vol.116 , pp. 2949-2956
    • Dickinson, R.1    Lieb, W.R.2    Franks, N.P.3
  • 31
    • 0031784872 scopus 로고    scopus 로고
    • Structural basis for the inhibition of firefly luciferase by a general anesthetic
    • Franks NP, Jenkins A, Conti E, Lieb WR, Brick P: Structural basis for the inhibition of firefly luciferase by a general anesthetic. Biophys J 1998; 75:2205-11
    • (1998) Biophys J , vol.75 , pp. 2205-2211
    • Franks, N.P.1    Jenkins, A.2    Conti, E.3    Lieb, W.R.4    Brick, P.5
  • 32
    • 16344374288 scopus 로고    scopus 로고
    • Structural basis for high-affinity volatile anesthetic binding in a natural 4-helix bundle protein
    • Liu R, Loll PJ, Eckenhoff RG: Structural basis for high-affinity volatile anesthetic binding in a natural 4-helix bundle protein. FASEB J 2005; 19:567-76
    • (2005) FASEB J , vol.19 , pp. 567-576
    • Liu, R.1    Loll, P.J.2    Eckenhoff, R.G.3
  • 34
    • 84893447984 scopus 로고    scopus 로고
    • Opposing effects of the anesthetic propofol at pentameric ligand-gated ion channels mediated by a common site
    • Lynagh T, Laube B: Opposing effects of the anesthetic propofol at pentameric ligand-gated ion channels mediated by a common site. J Neurosci 2014; 34:2155-9
    • (2014) J Neurosci , vol.34 , pp. 2155-2159
    • Lynagh, T.1    Laube, B.2
  • 35
    • 0028140369 scopus 로고
    • Molecular and cellular mechanisms of general anaesthesia
    • Franks NP, Lieb WR: Molecular and cellular mechanisms of general anaesthesia. Nature 1994; 367:607-14
    • (1994) Nature , vol.367 , pp. 607-614
    • Franks, N.P.1    Lieb, W.R.2
  • 36
    • 84860296064 scopus 로고    scopus 로고
    • Binding site and affinity prediction of general anesthetics to protein targets using docking
    • Liu R, Perez-Aguilar JM, Liang D, Saven JG: Binding site and affinity prediction of general anesthetics to protein targets using docking. Anesth Analg 2012; 114:947-55
    • (2012) Anesth Analg , vol.114 , pp. 947-955
    • Liu, R.1    Perez-Aguilar, J.M.2    Liang, D.3    Saven, J.G.4
  • 37
    • 84880048862 scopus 로고    scopus 로고
    • Specificity of intersubunit general anesthetic-binding sites in the transmembrane domain of the human 132-aminobutyric acid type A (GABAA) receptor
    • Chiara DC, Jayakar SS, Zhou X, Zhang X, Savechenkov PY, Bruzik KS, Miller KW, Cohen JB: Specificity of intersubunit general anesthetic-binding sites in the transmembrane domain of the human 132-aminobutyric acid type A (GABAA) receptor. J Biol Chem 2013; 288:19343-57
    • (2013) J Biol Chem , vol.288 , pp. 19343-19357
    • Chiara, D.C.1    Jayakar, S.S.2    Zhou, X.3    Zhang, X.4    Savechenkov, P.Y.5    Bruzik, K.S.6    Miller, K.W.7    Cohen, J.B.8
  • 38
    • 66449123447 scopus 로고    scopus 로고
    • Neurosteroids allosterically modulate binding of the anesthetic etomidate to gamma-aminobutyric acid type A receptors
    • Li GD, Chiara DC, Cohen JB, Olsen RW: Neurosteroids allosterically modulate binding of the anesthetic etomidate to gamma-aminobutyric acid type A receptors. J Biol Chem 2009; 284:11771-5
    • (2009) J Biol Chem , vol.284 , pp. 11771-11775
    • Li, G.D.1    Chiara, D.C.2    Cohen, J.B.3    Olsen, R.W.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.