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Volumn 16, Issue 16, 2015, Pages 1659-1666

Germline genetic variation in ETV6 and risk of childhood acute lymphoblastic leukaemia: A systematic genetic study

(32)  Moriyama, Takaya a,b   Metzger, Monika L a   Wu, Gang a   Nishii, Rina a,c   Qian, Maoxiang a   Devidas, Meenakshi d   Yang, Wenjian a   Cheng, Cheng a   Cao, Xueyuan a   Quinn, Emily a   Raimondi, Susana a   Gastier Foster, Julie M e   Raetz, Elizabeth f   Larsen, Eric g   Martin, Paul L h   Bowman, W Paul i   Winick, Naomi j   Komada, Yoshihiro b   Wang, Shuoguo a   Edmonson, Michael a   more..


Author keywords

[No Author keywords available]

Indexed keywords

TRANSCRIPTION FACTOR ETV6; REPRESSOR PROTEIN; TRANSCRIPTION FACTOR ETS; TUMOR MARKER;

EID: 84951304790     PISSN: 14702045     EISSN: 14745488     Source Type: Journal    
DOI: 10.1016/S1470-2045(15)00369-1     Document Type: Article
Times cited : (166)

References (55)
  • 1
    • 79952078495 scopus 로고    scopus 로고
    • Biology, risk stratification, and therapy of pediatric acute leukemias: an update
    • Pui CH, Carroll WL, Meshinchi S, Arceci RJ Biology, risk stratification, and therapy of pediatric acute leukemias: an update. J Clin Oncol 2011, 29:551-565.
    • (2011) J Clin Oncol , vol.29 , pp. 551-565
    • Pui, C.H.1    Carroll, W.L.2    Meshinchi, S.3    Arceci, R.J.4
  • 2
    • 84863772728 scopus 로고    scopus 로고
    • Improved survival for children and adolescents with acute lymphoblastic leukemia between 1990 and 2005: a report from the children's oncology group
    • Hunger SP, Lu X, Devidas M, et al. Improved survival for children and adolescents with acute lymphoblastic leukemia between 1990 and 2005: a report from the children's oncology group. J Clin Oncol 2012, 30:1663-1669.
    • (2012) J Clin Oncol , vol.30 , pp. 1663-1669
    • Hunger, S.P.1    Lu, X.2    Devidas, M.3
  • 3
    • 84907360666 scopus 로고    scopus 로고
    • A novel integrated cytogenetic and genomic classification refines risk stratification in pediatric acute lymphoblastic leukemia
    • Moorman AV, Enshaei A, Schwab C, et al. A novel integrated cytogenetic and genomic classification refines risk stratification in pediatric acute lymphoblastic leukemia. Blood 2014, 124:1434-1444.
    • (2014) Blood , vol.124 , pp. 1434-1444
    • Moorman, A.V.1    Enshaei, A.2    Schwab, C.3
  • 4
    • 57549090224 scopus 로고    scopus 로고
    • Treatment of childhood acute lymphoblastic leukemia
    • Stanulla M, Schrappe M Treatment of childhood acute lymphoblastic leukemia. Semin Hematol 2009, 46:52-63.
    • (2009) Semin Hematol , vol.46 , pp. 52-63
    • Stanulla, M.1    Schrappe, M.2
  • 5
    • 78650882963 scopus 로고    scopus 로고
    • Childhood leukaemia, nuclear sites, and population mixing
    • Kinlen L Childhood leukaemia, nuclear sites, and population mixing. Br J Cancer 2011, 104:12-18.
    • (2011) Br J Cancer , vol.104 , pp. 12-18
    • Kinlen, L.1
  • 6
    • 84931562132 scopus 로고    scopus 로고
    • Mechanisms of clonal evolution in childhood acute lymphoblastic leukemia
    • Swaminathan S, Klemm L, Park E, et al. Mechanisms of clonal evolution in childhood acute lymphoblastic leukemia. Nat Immunol 2015, 16:766-774.
    • (2015) Nat Immunol , vol.16 , pp. 766-774
    • Swaminathan, S.1    Klemm, L.2    Park, E.3
  • 7
    • 33644545382 scopus 로고    scopus 로고
    • Infection, immune responses and the aetiology of childhood leukaemia
    • Greaves M Infection, immune responses and the aetiology of childhood leukaemia. Nat Rev Cancer 2006, 6:193-203.
    • (2006) Nat Rev Cancer , vol.6 , pp. 193-203
    • Greaves, M.1
  • 8
    • 84869086592 scopus 로고    scopus 로고
    • Familial risks for childhood acute lymphocytic leukaemia in Sweden and Finland: far exceeding the effects of known germline variants
    • Kharazmi E, da Silva Filho MI, Pukkala E, Sundquist K, Thomsen H, Hemminki K Familial risks for childhood acute lymphocytic leukaemia in Sweden and Finland: far exceeding the effects of known germline variants. Br J Cancer 2012, 159:585-588.
    • (2012) Br J Cancer , vol.159 , pp. 585-588
    • Kharazmi, E.1    da Silva Filho, M.I.2    Pukkala, E.3    Sundquist, K.4    Thomsen, H.5    Hemminki, K.6
  • 9
    • 0036166879 scopus 로고    scopus 로고
    • Risks among siblings and twins for childhood acute lymphoid leukaemia: results from the Swedish Family-Cancer Database
    • Hemminki K, Jiang Y Risks among siblings and twins for childhood acute lymphoid leukaemia: results from the Swedish Family-Cancer Database. Leukemia 2002, 16:297-298.
    • (2002) Leukemia , vol.16 , pp. 297-298
    • Hemminki, K.1    Jiang, Y.2
  • 10
    • 69349101565 scopus 로고    scopus 로고
    • Loci on 7p12.2, 10q21.2 and 14q11.2 are associated with risk of childhood acute lymphoblastic leukemia
    • Papaemmanuil E, Hosking FJ, Vijayakrishnan J, et al. Loci on 7p12.2, 10q21.2 and 14q11.2 are associated with risk of childhood acute lymphoblastic leukemia. Nat Genet 2009, 41:1006-1010.
    • (2009) Nat Genet , vol.41 , pp. 1006-1010
    • Papaemmanuil, E.1    Hosking, F.J.2    Vijayakrishnan, J.3
  • 11
    • 69349091330 scopus 로고    scopus 로고
    • Germline genomic variants associated with childhood acute lymphoblastic leukemia
    • Trevino LR, Yang W, French D, et al. Germline genomic variants associated with childhood acute lymphoblastic leukemia. Nat Genet 2009, 41:1001-1005.
    • (2009) Nat Genet , vol.41 , pp. 1001-1005
    • Trevino, L.R.1    Yang, W.2    French, D.3
  • 12
    • 84888311432 scopus 로고    scopus 로고
    • Inherited GATA3 variants are associated with Ph-like childhood acute lymphoblastic leukemia and risk of relapse
    • Perez-Andreu V, Roberts KG, Harvey RC, et al. Inherited GATA3 variants are associated with Ph-like childhood acute lymphoblastic leukemia and risk of relapse. Nat Genet 2013, 45:1494-1498.
    • (2013) Nat Genet , vol.45 , pp. 1494-1498
    • Perez-Andreu, V.1    Roberts, K.G.2    Harvey, R.C.3
  • 13
    • 84891671233 scopus 로고    scopus 로고
    • Variation at 10p12.2 and 10p14 influences risk of childhood B-cell acute lymphoblastic leukemia and phenotype
    • Migliorini G, Fiege B, Hosking FJ, et al. Variation at 10p12.2 and 10p14 influences risk of childhood B-cell acute lymphoblastic leukemia and phenotype. Blood 2013, 122:3298-3307.
    • (2013) Blood , vol.122 , pp. 3298-3307
    • Migliorini, G.1    Fiege, B.2    Hosking, F.J.3
  • 14
    • 84933060281 scopus 로고    scopus 로고
    • Inherited coding variants at the CDKN2A locus influence susceptibility to acute lymphoblastic leukaemia in children
    • Xu H, Zhang H, Yang W, et al. Inherited coding variants at the CDKN2A locus influence susceptibility to acute lymphoblastic leukaemia in children. Nat Commun 2015, 6:7553.
    • (2015) Nat Commun , vol.6 , pp. 7553
    • Xu, H.1    Zhang, H.2    Yang, W.3
  • 15
    • 77952884769 scopus 로고    scopus 로고
    • Variation in CDKN2A at 9p21.3 influences childhood acute lymphoblastic leukemia risk
    • Sherborne AL, Hosking FJ, Prasad RB, et al. Variation in CDKN2A at 9p21.3 influences childhood acute lymphoblastic leukemia risk. Nat Genet 2010, 42:492-494.
    • (2010) Nat Genet , vol.42 , pp. 492-494
    • Sherborne, A.L.1    Hosking, F.J.2    Prasad, R.B.3
  • 16
    • 84877969387 scopus 로고    scopus 로고
    • Novel susceptibility variants at 10p12.31-12.2 for childhood acute lymphoblastic leukemia in ethnically diverse populations
    • Xu H, Yang W, Perez-Andreu V, et al. Novel susceptibility variants at 10p12.31-12.2 for childhood acute lymphoblastic leukemia in ethnically diverse populations. J Natl Cancer Inst 2013, 105:733-742.
    • (2013) J Natl Cancer Inst , vol.105 , pp. 733-742
    • Xu, H.1    Yang, W.2    Perez-Andreu, V.3
  • 17
    • 84860709956 scopus 로고    scopus 로고
    • Identification of germline susceptibility loci in ETV6-RUNX1-rearranged childhood acute lymphoblastic leukemia
    • Ellinghaus E, Stanulla M, Richter G, et al. Identification of germline susceptibility loci in ETV6-RUNX1-rearranged childhood acute lymphoblastic leukemia. Leukemia 2012, 26:902-909.
    • (2012) Leukemia , vol.26 , pp. 902-909
    • Ellinghaus, E.1    Stanulla, M.2    Richter, G.3
  • 18
    • 0342905433 scopus 로고    scopus 로고
    • Risks of leukaemia and solid tumours in individuals with Down's syndrome
    • Hasle H, Clemmensen IH, Mikkelsen M Risks of leukaemia and solid tumours in individuals with Down's syndrome. Lancet 2000, 355:165-169.
    • (2000) Lancet , vol.355 , pp. 165-169
    • Hasle, H.1    Clemmensen, I.H.2    Mikkelsen, M.3
  • 19
    • 70350680415 scopus 로고    scopus 로고
    • Rearrangement of CRLF2 in B-progenitor- and Down syndrome-associated acute lymphoblastic leukemia
    • Mullighan CG, Collins-Underwood JR, Phillips LA, et al. Rearrangement of CRLF2 in B-progenitor- and Down syndrome-associated acute lymphoblastic leukemia. Nat Genet 2009, 41:1243-1246.
    • (2009) Nat Genet , vol.41 , pp. 1243-1246
    • Mullighan, C.G.1    Collins-Underwood, J.R.2    Phillips, L.A.3
  • 20
    • 84897528140 scopus 로고    scopus 로고
    • Constitutional and somatic rearrangement of chromosome 21 in acute lymphoblastic leukaemia
    • Li Y, Schwab C, Ryan SL, et al. Constitutional and somatic rearrangement of chromosome 21 in acute lymphoblastic leukaemia. Nature 2014, 508:98-102.
    • (2014) Nature , vol.508 , pp. 98-102
    • Li, Y.1    Schwab, C.2    Ryan, S.L.3
  • 21
    • 84884999671 scopus 로고    scopus 로고
    • A recurrent germline PAX5 mutation confers susceptibility to pre-B cell acute lymphoblastic leukemia
    • Shah S, Schrader KA, Waanders E, et al. A recurrent germline PAX5 mutation confers susceptibility to pre-B cell acute lymphoblastic leukemia. Nat Genet 2013, 45:1226-1231.
    • (2013) Nat Genet , vol.45 , pp. 1226-1231
    • Shah, S.1    Schrader, K.A.2    Waanders, E.3
  • 22
    • 84887805156 scopus 로고    scopus 로고
    • Genetic loss of SH2B3 in acute lymphoblastic leukemia
    • Perez-Garcia A, Ambesi-Impiombato A, Hadler M, et al. Genetic loss of SH2B3 in acute lymphoblastic leukemia. Blood 2013, 122:2425-2432.
    • (2013) Blood , vol.122 , pp. 2425-2432
    • Perez-Garcia, A.1    Ambesi-Impiombato, A.2    Hadler, M.3
  • 23
    • 84874647204 scopus 로고    scopus 로고
    • The genomic landscape of hypodiploid acute lymphoblastic leukemia
    • Holmfeldt L, Wei L, Diaz-Flores E, et al. The genomic landscape of hypodiploid acute lymphoblastic leukemia. Nat Genet 2013, 45:242-252.
    • (2013) Nat Genet , vol.45 , pp. 242-252
    • Holmfeldt, L.1    Wei, L.2    Diaz-Flores, E.3
  • 24
    • 0000418386 scopus 로고    scopus 로고
    • The TEL/ETV6 gene is required specifically for hematopoiesis in the bone marrow
    • Wang LC, Swat W, Fujiwara Y, et al. The TEL/ETV6 gene is required specifically for hematopoiesis in the bone marrow. Genes Dev 1998, 12:2392-2402.
    • (1998) Genes Dev , vol.12 , pp. 2392-2402
    • Wang, L.C.1    Swat, W.2    Fujiwara, Y.3
  • 25
    • 84888585803 scopus 로고    scopus 로고
    • Molecular mechanisms of ETS transcription factor-mediated tumorigenesis
    • Kar A, Gutierrez-Hartmann A Molecular mechanisms of ETS transcription factor-mediated tumorigenesis. Crit Rev Biochem Mol Biol 2013, 48:522-543.
    • (2013) Crit Rev Biochem Mol Biol , vol.48 , pp. 522-543
    • Kar, A.1    Gutierrez-Hartmann, A.2
  • 26
    • 79959794787 scopus 로고    scopus 로고
    • Clinical effect of point mutations in myelodysplastic syndromes
    • Bejar R, Stevenson K, Abdel-Wahab O, et al. Clinical effect of point mutations in myelodysplastic syndromes. N Engl J Med 2011, 364:2496-2506.
    • (2011) N Engl J Med , vol.364 , pp. 2496-2506
    • Bejar, R.1    Stevenson, K.2    Abdel-Wahab, O.3
  • 28
    • 84856756817 scopus 로고    scopus 로고
    • ETV6-RUNX1-positive childhood acute lymphoblastic leukemia: improved outcome with contemporary therapy
    • Bhojwani D, Pei D, Sandlund JT, et al. ETV6-RUNX1-positive childhood acute lymphoblastic leukemia: improved outcome with contemporary therapy. Leukemia 2012, 26:265-270.
    • (2012) Leukemia , vol.26 , pp. 265-270
    • Bhojwani, D.1    Pei, D.2    Sandlund, J.T.3
  • 29
    • 84926216729 scopus 로고    scopus 로고
    • Germline ETV6 mutations in familial thrombocytopenia and hematologic malignancy
    • Zhang MY, Churpek JE, Keel SB, et al. Germline ETV6 mutations in familial thrombocytopenia and hematologic malignancy. Nat Genet 2015, 47:180-185.
    • (2015) Nat Genet , vol.47 , pp. 180-185
    • Zhang, M.Y.1    Churpek, J.E.2    Keel, S.B.3
  • 30
    • 84929130522 scopus 로고    scopus 로고
    • Germline mutations in ETV6 are associated with thrombocytopenia, red cell macrocytosis and predisposition to lymphoblastic leukemia
    • Noetzli L, Lo RW, Lee-Sherick AB, et al. Germline mutations in ETV6 are associated with thrombocytopenia, red cell macrocytosis and predisposition to lymphoblastic leukemia. Nat Genet 2015, 47:535-538.
    • (2015) Nat Genet , vol.47 , pp. 535-538
    • Noetzli, L.1    Lo, R.W.2    Lee-Sherick, A.B.3
  • 31
    • 84937779216 scopus 로고    scopus 로고
    • Germline ETV6 mutations confer susceptibility to acute lymphoblastic leukemia and thrombocytopenia
    • Topka S, Vijai J, Walsh MF, et al. Germline ETV6 mutations confer susceptibility to acute lymphoblastic leukemia and thrombocytopenia. PLoS Genet 2015, 11:e1005262.
    • (2015) PLoS Genet , vol.11 , pp. e1005262
    • Topka, S.1    Vijai, J.2    Walsh, M.F.3
  • 32
    • 0032528447 scopus 로고    scopus 로고
    • Early intensification of intrathecal chemotherapy virtually eliminates central nervous system relapse in children with acute lymphoblastic leukemia
    • Pui CH, Mahmoud HH, Rivera GK, Hancock ML, Sandlund JT, Behm FG, et al. Early intensification of intrathecal chemotherapy virtually eliminates central nervous system relapse in children with acute lymphoblastic leukemia. Blood 1998, 92:411-415.
    • (1998) Blood , vol.92 , pp. 411-415
    • Pui, C.H.1    Mahmoud, H.H.2    Rivera, G.K.3    Hancock, M.L.4    Sandlund, J.T.5    Behm, F.G.6
  • 33
    • 7244242363 scopus 로고    scopus 로고
    • Improved outcome for children with acute lymphoblastic leukemia: results of Total Therapy Study XIIIB at St Jude Children's Research Hospital
    • Pui CH, Sandlund JT, Pei D, et al. Improved outcome for children with acute lymphoblastic leukemia: results of Total Therapy Study XIIIB at St Jude Children's Research Hospital. Blood 2004, 104:2690-2696.
    • (2004) Blood , vol.104 , pp. 2690-2696
    • Pui, C.H.1    Sandlund, J.T.2    Pei, D.3
  • 34
    • 67649410242 scopus 로고    scopus 로고
    • Treating childhood acute lymphoblastic leukemia without cranial irradiation
    • Pui CH, Campana D, Pei D, et al. Treating childhood acute lymphoblastic leukemia without cranial irradiation. N Engl J Med 2009, 360:2730-2741.
    • (2009) N Engl J Med , vol.360 , pp. 2730-2741
    • Pui, C.H.1    Campana, D.2    Pei, D.3
  • 35
    • 47049093795 scopus 로고    scopus 로고
    • Clinical significance of minimal residual disease in childhood acute lymphoblastic leukemia and its relationship to other prognostic factors: a Children's Oncology Group study
    • Borowitz MJ, Devidas M, Hunger SP, et al. Clinical significance of minimal residual disease in childhood acute lymphoblastic leukemia and its relationship to other prognostic factors: a Children's Oncology Group study. Blood 2008, 111:5477-5485.
    • (2008) Blood , vol.111 , pp. 5477-5485
    • Borowitz, M.J.1    Devidas, M.2    Hunger, S.P.3
  • 36
    • 84940063254 scopus 로고    scopus 로고
    • Prognostic significance of minimal residual disease in high risk B-ALL: a report from Children's Oncology Group study AALL0232
    • Borowitz MJ, Wood BL, Devidas M, et al. Prognostic significance of minimal residual disease in high risk B-ALL: a report from Children's Oncology Group study AALL0232. Blood 2015, 126:964-971.
    • (2015) Blood , vol.126 , pp. 964-971
    • Borowitz, M.J.1    Wood, B.L.2    Devidas, M.3
  • 37
    • 84863556835 scopus 로고    scopus 로고
    • Evolution and functional impact of rare coding variation from deep sequencing of human exomes
    • Tennessen JA, Bigham AW, O'Connor TD, et al. Evolution and functional impact of rare coding variation from deep sequencing of human exomes. Science 2012, 337:64-69.
    • (2012) Science , vol.337 , pp. 64-69
    • Tennessen, J.A.1    Bigham, A.W.2    O'Connor, T.D.3
  • 38
    • 0034118493 scopus 로고    scopus 로고
    • Inference of population structure using multilocus genotype data
    • Pritchard JK, Stephens M, Donnelly P Inference of population structure using multilocus genotype data. Genetics 2000, 155:945-959.
    • (2000) Genetics , vol.155 , pp. 945-959
    • Pritchard, J.K.1    Stephens, M.2    Donnelly, P.3
  • 39
    • 79952188025 scopus 로고    scopus 로고
    • Ancestry and pharmacogenomics of relapse in acute lymphoblastic leukemia
    • Yang JJ, Cheng C, Devidas M, et al. Ancestry and pharmacogenomics of relapse in acute lymphoblastic leukemia. Nat Genet 2011, 43:237-241.
    • (2011) Nat Genet , vol.43 , pp. 237-241
    • Yang, J.J.1    Cheng, C.2    Devidas, M.3
  • 40
    • 84937797142 scopus 로고    scopus 로고
    • Genome-wide analysis links NFATC2 with asparaginase hypersensitivity
    • Fernandez CA, Smith C, Yang W, et al. Genome-wide analysis links NFATC2 with asparaginase hypersensitivity. Blood 2015, 126:69-75.
    • (2015) Blood , vol.126 , pp. 69-75
    • Fernandez, C.A.1    Smith, C.2    Yang, W.3
  • 41
    • 79952596594 scopus 로고    scopus 로고
    • Bambino: a variant detector and alignment viewer for next-generation sequencing data in the SAM/BAM format
    • Edmonson MN, Zhang J, Yan C, Finney RP, Meerzaman DM, Buetow KH Bambino: a variant detector and alignment viewer for next-generation sequencing data in the SAM/BAM format. Bioinformatics 2011, 27:865-866.
    • (2011) Bioinformatics , vol.27 , pp. 865-866
    • Edmonson, M.N.1    Zhang, J.2    Yan, C.3    Finney, R.P.4    Meerzaman, D.M.5    Buetow, K.H.6
  • 42
    • 79955483667 scopus 로고    scopus 로고
    • A framework for variation discovery and genotyping using next-generation DNA sequencing data
    • DePristo MA, Banks E, Poplin R, et al. A framework for variation discovery and genotyping using next-generation DNA sequencing data. Nat Genet 2011, 43:491-498.
    • (2011) Nat Genet , vol.43 , pp. 491-498
    • DePristo, M.A.1    Banks, E.2    Poplin, R.3
  • 43
    • 84946040120 scopus 로고    scopus 로고
    • COSMIC: exploring the world's knowledge of somatic mutations in human cancer
    • Forbes SA, Beare D, Gunasekaran P, et al. COSMIC: exploring the world's knowledge of somatic mutations in human cancer. Nucleic Acids Res 2015, 43(database issue):D805-D811.
    • (2015) Nucleic Acids Res , vol.43 , Issue.database issue , pp. D805-D811
    • Forbes, S.A.1    Beare, D.2    Gunasekaran, P.3
  • 44
    • 84880535720 scopus 로고    scopus 로고
    • ACMG recommendations for reporting of incidental findings in clinical exome and genome sequencing
    • Green RC, Berg JS, Grody WW, et al. ACMG recommendations for reporting of incidental findings in clinical exome and genome sequencing. Genet Med 2013, 15:565-574.
    • (2013) Genet Med , vol.15 , pp. 565-574
    • Green, R.C.1    Berg, J.S.2    Grody, W.W.3
  • 45
    • 84891837451 scopus 로고    scopus 로고
    • The Human Gene Mutation Database: building a comprehensive mutation repository for clinical and molecular genetics, diagnostic testing and personalized genomic medicine
    • Stenson PD, Mort M, Ball EV, Shaw K, Phillips A, Cooper DN The Human Gene Mutation Database: building a comprehensive mutation repository for clinical and molecular genetics, diagnostic testing and personalized genomic medicine. Hum Genet 2014, 133:1-9.
    • (2014) Hum Genet , vol.133 , pp. 1-9
    • Stenson, P.D.1    Mort, M.2    Ball, E.V.3    Shaw, K.4    Phillips, A.5    Cooper, D.N.6
  • 46
    • 84891809093 scopus 로고    scopus 로고
    • ClinVar: public archive of relationships among sequence variation and human phenotype
    • Landrum MJ, Lee JM, Riley GR, et al. ClinVar: public archive of relationships among sequence variation and human phenotype. Nucleic Acids Res 2014, 42(database issue):D980-D985.
    • (2014) Nucleic Acids Res , vol.42 , Issue.database issue , pp. D980-D985
    • Landrum, M.J.1    Lee, J.M.2    Riley, G.R.3
  • 47
    • 84895858942 scopus 로고    scopus 로고
    • A general framework for estimating the relative pathogenicity of human genetic variants
    • Kircher M, Witten DM, Jain P, O'Roak BJ, Cooper GM, Shendure J A general framework for estimating the relative pathogenicity of human genetic variants. Nat Genet 2014, 46:310-315.
    • (2014) Nat Genet , vol.46 , pp. 310-315
    • Kircher, M.1    Witten, D.M.2    Jain, P.3    O'Roak, B.J.4    Cooper, G.M.5    Shendure, J.6
  • 48
    • 1542532754 scopus 로고    scopus 로고
    • A proportional hazards model for the subdistribution of a competing risk
    • Fine JP, Gray RJ A proportional hazards model for the subdistribution of a competing risk. J Am Stat Assoc 1999, 94:496-509.
    • (1999) J Am Stat Assoc , vol.94 , pp. 496-509
    • Fine, J.P.1    Gray, R.J.2
  • 49
    • 84895920876 scopus 로고    scopus 로고
    • Steric mechanism of auto-inhibitory regulation of specific and non-specific DNA binding by the ETS transcriptional repressor ETV6
    • De S, Chan AC, Coyne HJ, et al. Steric mechanism of auto-inhibitory regulation of specific and non-specific DNA binding by the ETS transcriptional repressor ETV6. J Mol Biol 2014, 426:1390-1406.
    • (2014) J Mol Biol , vol.426 , pp. 1390-1406
    • De, S.1    Chan, A.C.2    Coyne, H.J.3
  • 50
    • 84933518382 scopus 로고    scopus 로고
    • Inherited genetic variation in childhood acute lymphoblastic leukemia
    • Moriyama T, Relling MV, Yang JJ Inherited genetic variation in childhood acute lymphoblastic leukemia. Blood 2015, 125:3988-3995.
    • (2015) Blood , vol.125 , pp. 3988-3995
    • Moriyama, T.1    Relling, M.V.2    Yang, J.J.3
  • 51
    • 84895803000 scopus 로고    scopus 로고
    • RAG-mediated recombination is the predominant driver of oncogenic rearrangement in ETV6-RUNX1 acute lymphoblastic leukemia
    • Papaemmanuil E, Rapado I, Li Y, et al. RAG-mediated recombination is the predominant driver of oncogenic rearrangement in ETV6-RUNX1 acute lymphoblastic leukemia. Nat Genet 2014, 46:116-125.
    • (2014) Nat Genet , vol.46 , pp. 116-125
    • Papaemmanuil, E.1    Rapado, I.2    Li, Y.3
  • 52
    • 84927692640 scopus 로고    scopus 로고
    • Clonal origins of ETV6-RUNX1(+) acute lymphoblastic leukemia: studies in monozygotic twins
    • Alpar D, Wren D, Ermini L, et al. Clonal origins of ETV6-RUNX1(+) acute lymphoblastic leukemia: studies in monozygotic twins. Leukemia 2015, 29:839-846.
    • (2015) Leukemia , vol.29 , pp. 839-846
    • Alpar, D.1    Wren, D.2    Ermini, L.3
  • 53
    • 0141634051 scopus 로고    scopus 로고
    • Origins of chromosome translocations in childhood leukaemia
    • Greaves MF, Wiemels J Origins of chromosome translocations in childhood leukaemia. Nat Rev Cancer 2003, 3:639-649.
    • (2003) Nat Rev Cancer , vol.3 , pp. 639-649
    • Greaves, M.F.1    Wiemels, J.2
  • 54
    • 0034307660 scopus 로고    scopus 로고
    • Recruitment of the nuclear receptor corepressor N-CoR by the TEL moiety of the childhood leukemia-associated TEL-AML1 oncoprotein
    • Guidez F, Petrie K, Ford AM, et al. Recruitment of the nuclear receptor corepressor N-CoR by the TEL moiety of the childhood leukemia-associated TEL-AML1 oncoprotein. Blood 2000, 96:2557-2561.
    • (2000) Blood , vol.96 , pp. 2557-2561
    • Guidez, F.1    Petrie, K.2    Ford, A.M.3
  • 55
    • 4644274431 scopus 로고    scopus 로고
    • Tel/Etv6 is an essential and selective regulator of adult hematopoietic stem cell survival
    • Hock H, Meade E, Medeiros S, et al. Tel/Etv6 is an essential and selective regulator of adult hematopoietic stem cell survival. Genes Dev 2004, 18:2336-2341.
    • (2004) Genes Dev , vol.18 , pp. 2336-2341
    • Hock, H.1    Meade, E.2    Medeiros, S.3


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