Inherited coding variants at the CDKN2A locus influence susceptibility to acute lymphoblastic leukaemia in children

Nature Communications

Volumn 6, Issue , 2015, Pages

  Xu, Heng ^a,b   Zhang, Hui ^a,c   Yang, Wenjian ^a   Yadav, Rachita ^d   Morrison, Alanna C ^e   Qian, Maoxiang ^a   Devidas, Meenakshi ^f   Liu, Yu ^a   Perez Andreu, Virginia ^a   Zhao, Xujie ^a   Gastier Foster, Julie M ^g   Lupo, Philip J ^h   Neale, Geoff ^a   Raetz, Elizabeth ⁱ   Larsen, Eric ^j   Bowman, W Paul ^k   Carroll, William L ^l   Winick, Naomi ^m   Williams, Richard ⁿ   Hansen, Torben ^o   Holm, Jens Christian ^p   Mardis, Elaine ^q   Fulton, Robert ^q   Pui, Ching Hon ^a   Zhang, Jinghui ^a   Mullighan, Charles G ^a   Evans, William E ^a   Hunger, Stephen P ^r   Gupta, Ramneek ^d   Schmiegelow, Kjeld ^s   Loh, Mignon L ^t   Relling, Mary V ^a   Yang, Jun J ^a   more..

^a ST JUDE CHILDREN S RESEARCH HOSPITAL   (United States)

^b SICHUAN UNIVERSITY   (China)

^c GUANGZHOU MEDICAL UNIVERSITY   (China)

^d TECHNICAL UNIVERSITY OF DENMARK   (Denmark)

^e UNIVERSITY OF TEXAS SCHOOL OF PUBLIC HEALTH   (United States)

^f UNIVERSITY OF FLORIDA COLLEGE OF MEDICINE   (United States)

^g OHIO STATE UNIVERSITY   (United States)

^h BAYLOR COLLEGE OF MEDICINE   (United States)

ⁱ UNIVERSITY OF UTAH   (United States)

^j Maine Children's Cancer Program Scarborough   (United States)

^k Children's Medical Center   (United States)

^l NEW YORK UNIVERSITY   (United States)

^m UNIVERSITY OF TEXAS SOUTHWESTERN MEDICAL CENTER   (United States)

ⁿ Puma Biotechnology Inc   (United States)

^o Capital Region   (Denmark)

^p Mental Health Services CPH   (Denmark)

^q WASHINGTON UNIVERSITY SCHOOL OF MEDICINE   (United States)

^r CHILDREN S HOSPITAL OF PHILADELPHIA   (United States)

^s Rigshospitalet   (Denmark)

^t UNIVERSITY OF CALIFORNIA   (United States)

more..

Author keywords

[No Author keywords available]

Indexed keywords

CYCLIN DEPENDENT KINASE INHIBITOR 2A; CYCLIN DEPENDENT KINASE INHIBITOR 2B; ARID5B PROTEIN, HUMAN; CDKN2B PROTEIN, HUMAN; DNA BINDING PROTEIN; IKAROS TRANSCRIPTION FACTOR; IKZF1 PROTEIN, HUMAN; TRANSCRIPTION FACTOR;

CANCER; CHILD HEALTH; DISEASE INCIDENCE; GENETIC VARIATION; GENOME; GERM CELL; HERITABILITY; PROTEIN;

ACUTE LYMPHOBLASTIC LEUKEMIA; ALLELE; ARTICLE; CHILD; CHILDHOOD CANCER; CONTROLLED STUDY; EUROPEAN AMERICAN; EXOME; GENE LOCUS; GENETIC SUSCEPTIBILITY; GENETIC VARIABILITY; GENOTYPE; HEMATOPOIETIC STEM CELL; HUMAN; LEUKEMOGENESIS; MAJOR CLINICAL STUDY; MISSENSE MUTATION; ANIMAL; CASE CONTROL STUDY; GENETIC PREDISPOSITION; GENETIC VARIATION; GENETICS; GENOME-WIDE ASSOCIATION STUDY; GERMLINE MUTATION; HEK293 CELL LINE; METABOLISM; MOUSE; SITE DIRECTED MUTAGENESIS;

ANIMALS; CASE-CONTROL STUDIES; CHILD; CYCLIN-DEPENDENT KINASE INHIBITOR P15; CYCLIN-DEPENDENT KINASE INHIBITOR P16; DNA-BINDING PROTEINS; GENETIC PREDISPOSITION TO DISEASE; GENETIC VARIATION; GENOME-WIDE ASSOCIATION STUDY; GENOTYPE; GERM-LINE MUTATION; HEK293 CELLS; HEMATOPOIETIC STEM CELLS; HUMANS; IKAROS TRANSCRIPTION FACTOR; MICE; MUTAGENESIS, SITE-DIRECTED; MUTATION, MISSENSE; PRECURSOR B-CELL LYMPHOBLASTIC LEUKEMIA-LYMPHOMA; PRECURSOR CELL LYMPHOBLASTIC LEUKEMIA-LYMPHOMA; TRANSCRIPTION FACTORS;

EID: 84933060281     PISSN: None     EISSN: 20411723     Source Type: Journal    
DOI: 10.1038/ncomms8553     Document Type: Article

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