Hormone Replacement Therapy Associated White Blood Cell DNA Methylation and Gene Expression are Associated With Within-Pair Differences of Body Adiposity and Bone Mass

Twin Research and Human Genetics

Volumn 18, Issue 6, 2015, Pages 647-661

  Bahl, Aileen ^a   Pöllänen, Eija ^b   Ismail, Khadeeja ^a   Sipilä, Sarianna ^b   Mikkola, Tuija M ^b   Berglund, Eva ^c   Lindqvist, Carl Mårten ^c   Syvänen, Ann Christine ^c   Rantanen, Taina ^b   Kaprio, Jaakko ^a,d   Kovanen, Vuokko ^b   Ollikainen, Miina ^a  

^a UNIVERSITY OF HELSINKI   (Finland)

^b UNIVERSITY OF JYVÄSKYLÄ   (Finland)

^c UPPSALA UNIVERSITY   (Sweden)

^d NATIONAL PUBLIC HEALTH INSTITUTE   (Finland)

Author keywords

body composition; bone mineral content; discordant monozygotic twin pair design; DNA methylation; epigenetic regulation; gene expression; hormone replacement therapy; HRT; menopause; skeletal muscle composition

Indexed keywords

C REACTIVE PROTEIN; CHOLESTEROL; DNA; ESTRADIOL; ESTROGEN; HIGH DENSITY LIPOPROTEIN CHOLESTEROL; LOW DENSITY LIPOPROTEIN CHOLESTEROL; PROGESTERONE; RNA; TRIACYLGLYCEROL;

ACBA1 GENE; ADULT; AGED; ARTICLE; BLOOD SAMPLING; BODY COMPOSITION; BODY FAT; BONE MASS; BONE MINERAL; CCL5 GENE; CLINICAL ARTICLE; CONTROLLED STUDY; DNA EXTRACTION; DNA METHYLATION; FASLG GENE; FEMALE; GENE; GENE EXPRESSION; GENE IDENTIFICATION; HORMONE SUBSTITUTION; HUMAN; LEAN BODY WEIGHT; LEUKOCYTE; LIPID BLOOD LEVEL; MENOPAUSAL SYNDROME; MIDDLE AGED; MONOZYGOTIC TWINS; OBESITY; PHENOTYPE; PPP2R2B GENE; PRIORITY JOURNAL; RNA EXTRACTION; UHRF1 GENE; BODY MASS; BONE DENSITY; COMPARATIVE STUDY; GENETICS; GENOME-WIDE ASSOCIATION STUDY; POSTMENOPAUSE; TWINS;

ADIPOSITY; BODY MASS INDEX; BONE DENSITY; DNA METHYLATION; FEMALE; GENE EXPRESSION; GENOME-WIDE ASSOCIATION STUDY; HORMONE REPLACEMENT THERAPY; HUMANS; LEUKOCYTES; POSTMENOPAUSE;

EID: 84951171861     PISSN: 18324274     EISSN: 18392628     Source Type: Journal    
DOI: 10.1017/thg.2015.82     Document Type: Article

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