Reducing the risk of false discovery enabling identification of biologically significant genome-wide methylation status using the HumanMethylation450 array

BMC Genomics

Volumn 15, Issue 1, 2014, Pages

  Naeem, Haroon ^a,e   Wong, Nicholas C ^a,d   Chatterton, Zac ^a   Hong, Matthew K H ^a   Pedersen, John S ^b,c   Corcoran, Niall M ^a   Hovens, Christopher M ^a   Macintyre, Geoff ^a,e  

^a UNIVERSITY OF MELBOURNE   (Australia)

^b Tissupath Pty Ltd   (Australia)

^c MONASH UNIVERSITY   (Australia)

^d AUSTIN HOSPITAL   (Australia)

^e UNIVERSITY OF MELBOURNE   (Australia)

Author keywords

Cancer; Epigenetics; Epigenome wide association studies; EWAS; HM450K bead array; HumanMethylation450K BeadChip; INDELS; Repetitive regions of DNA; SNP arrays; SNPs

Indexed keywords

ARTICLE; BLOOD SAMPLING; CPG ISLAND; DNA HYBRIDIZATION; DNA METHYLATION; EPIGENETICS; GENE DELETION; GENE INSERTION; GENE INTERACTION; GENE MAPPING; HEREDITY; HETEROZYGOSITY; HUMAN; IMMUNOPRECIPITATION; MOLECULAR PROBE; NUCLEOTIDE SEQUENCE; PROSTATE CANCER; PROTEIN PROTEIN INTERACTION; RISK FACTOR; SINGLE NUCLEOTIDE POLYMORPHISM; DNA MICROARRAY; DNA SEQUENCE; GENE EXPRESSION REGULATION; GENOTYPE; HIGH THROUGHPUT SEQUENCING; HUMAN GENOME;

CPG ISLANDS; DNA METHYLATION; GENE DELETION; GENOME, HUMAN; GENOTYPE; HIGH-THROUGHPUT NUCLEOTIDE SEQUENCING; HUMANS; MUTAGENESIS, INSERTIONAL; OLIGONUCLEOTIDE ARRAY SEQUENCE ANALYSIS; POLYMORPHISM, SINGLE NUCLEOTIDE; PROTEIN INTERACTION MAPS; SEQUENCE ANALYSIS, DNA;

EID: 84892645283     PISSN: None     EISSN: 14712164     Source Type: Journal    
DOI: 10.1186/1471-2164-15-51     Document Type: Article

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