UHRF1 is associated with epigenetic silencing of BRCA1 in sporadic breast cancer

Breast Cancer Research and Treatment

Volumn 123, Issue 2, 2010, Pages 359-373

  Jin, Wei ^a   Chen, Li ^a   Chen, Ying ^a   Xu, Si Guang ^a   Di, Gen Hong ^a   Yin, Wen Jin ^a   Wu, Jiong ^a   Shao, Zhi Ming ^a  

^a FUDAN UNIVERSITY   (China)

Author keywords

BRCA1 promoter; DNA methylation; Histone modification; UHRF1

Indexed keywords

BINDING PROTEIN; BRCA1 PROTEIN; DNA; DNA METHYLTRANSFERASE 1; HISTONE ACETYLTRANSFERASE PCAF; HISTONE DEACETYLASE 1; HISTONE H3; HISTONE H4; HISTONE LYSINE METHYLTRANSFERASE; MYOD PROTEIN; PROTEIN P300; UBIQUITIN LIKE CONTAINING PHD AND RING FINGER DOMAIN 1 PROTEIN; UNCLASSIFIED DRUG;

ARTICLE; BREAST CANCER; CLINICAL ARTICLE; CONTROLLED STUDY; DEACETYLATION; DEMETHYLATION; DNA METHYLATION; EPIGENETICS; FEMALE; GENE OVEREXPRESSION; GENE SILENCING; GENETIC MARKER; HUMAN; HUMAN CELL; HUMAN TISSUE; PRIORITY JOURNAL; PROMOTER REGION; PROTEIN MODIFICATION; TRANSCRIPTION REGULATION;

ACETYLATION; BINDING SITES; BRCA1 PROTEIN; BREAST NEOPLASMS; CARCINOMA, DUCTAL, BREAST; CCAAT-ENHANCER-BINDING PROTEINS; CELL LINE, TUMOR; CHROMATIN ASSEMBLY AND DISASSEMBLY; CHROMATIN IMMUNOPRECIPITATION; CREB-BINDING PROTEIN; DNA (CYTOSINE-5-)-METHYLTRANSFERASE; DNA METHYLATION; DOSE-RESPONSE RELATIONSHIP, DRUG; E1A-ASSOCIATED P300 PROTEIN; EPIGENESIS, GENETIC; ESTRADIOL; FEMALE; GENE EXPRESSION REGULATION, NEOPLASTIC; GENE SILENCING; HISTOCOMPATIBILITY ANTIGENS; HISTONE DEACETYLASE 1; HISTONE-LYSINE N-METHYLTRANSFERASE; HISTONES; HUMANS; HYDROGEN PEROXIDE; IMMUNOHISTOCHEMISTRY; METHYLATION; MYOD PROTEIN; OXIDANTS; OXIDATIVE STRESS; PROMOTER REGIONS, GENETIC; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; RNA INTERFERENCE; TRANSCRIPTION, GENETIC; TRANSFECTION;

EID: 77956186851     PISSN: 01676806     EISSN: 15737217     Source Type: Journal    
DOI: 10.1007/s10549-009-0652-2     Document Type: Article

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