Lipopolysaccharide-induced pulmonary endothelial barrier disruption and lung edema: Critical role for bicarbonate stimulation of AC10

American Journal of Physiology - Lung Cellular and Molecular Physiology

Volumn 309, Issue 12, 2015, Pages L1430-L1437

  Nickols, Jordan ^a   Obiako, Boniface ^b   Ramila, K C ^a   Putinta, Kevin ^a   Schilling, Sarah ^c   Sayner, Sarah L ^a,b  

^a UNIVERSITY OF SOUTH ALABAMA   (United States)

^b UNIVERSITY OF SOUTH ALABAMA COLLEGE OF MEDICINE   (United States)

^c UNIVERSITY OF APPLIED SCIENCES BINGEN   (Germany)

Author keywords

Bicarbonate; Compartmentalized cAMP; Lipopolysaccharide; Lung edema; Soluble adenylate cyclase

Indexed keywords

ADENYLATE CYCLASE; ADENYLATE CYCLASE INHIBITOR; ADENYLATE CYCLASE ISOFORM 10; BICARBONATE; ESCHERICHIA COLI LIPOPOLYSACCHARIDE; KH 7; UNCLASSIFIED DRUG; CYCLIC AMP; ISOPROTEIN; LIPOPOLYSACCHARIDE;

ADULT; ANIMAL CELL; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CAPILLARY ENDOTHELIAL CELL; CELL MEMBRANE PERMEABILITY; CONTROLLED STUDY; ENDOTHELIAL DYSFUNCTION; ISOLATED LUNG; LUNG EDEMA; LUNG ENDOTHELIUM; MALE; NONHUMAN; PERMEABILITY BARRIER; PRIORITY JOURNAL; PROTEIN FUNCTION; RAT; SEPSIS; ADULT RESPIRATORY DISTRESS SYNDROME; ANIMAL; CAPILLARY PERMEABILITY; CELL MEMBRANE; CHEMICALLY INDUCED; CYTOSOL; DRUG EFFECTS; ENDOTHELIUM CELL; LUNG; METABOLISM; SPRAGUE DAWLEY RAT; VASCULAR ENDOTHELIUM;

ADENYLYL CYCLASES; ANIMALS; BICARBONATES; CAPILLARY PERMEABILITY; CELL MEMBRANE; CYCLIC AMP; CYTOSOL; ENDOTHELIAL CELLS; ENDOTHELIUM, VASCULAR; LIPOPOLYSACCHARIDES; LUNG; MALE; PROTEIN ISOFORMS; PULMONARY EDEMA; RATS, SPRAGUE-DAWLEY; RESPIRATORY DISTRESS SYNDROME, ADULT; SEPSIS;

EID: 84951081011     PISSN: 10400605     EISSN: 15221504     Source Type: Journal    
DOI: 10.1152/ajplung.00067.2015     Document Type: Article

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