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Volumn 45, Issue 2, 2015, Pages 483-490

HFE gene variants and iron-induced oxygen radical generation in idiopathic pulmonary fibrosis

Author keywords

[No Author keywords available]

Indexed keywords

DEFEROXAMINE; DICHLORODIHYDROFLUORESCEIN DIACETATE; HEMOSIDERIN; HFE PROTEIN; IRON; MALONALDEHYDE; REACTIVE OXYGEN METABOLITE; TRANSFERRIN; HFE PROTEIN, HUMAN; HLA ANTIGEN CLASS 1; MEMBRANE PROTEIN; OXYGEN;

EID: 84950170987     PISSN: 09031936     EISSN: 13993003     Source Type: Journal    
DOI: 10.1183/09031936.00104814     Document Type: Article
Times cited : (30)

References (43)
  • 1
    • 84881669432 scopus 로고    scopus 로고
    • An official American Thoracic Society/European Respiratory Society statement: Update of the international multidisciplinary classification of the idiopathic interstitial pneumonias
    • Travis WD, Costabel U, Hansell DM, et al. An official American Thoracic Society/European Respiratory Society statement: Update of the international multidisciplinary classification of the idiopathic interstitial pneumonias. Am J Respir Crit Care Med 2013;188:733-748.
    • (2013) Am J Respir Crit Care Med , vol.188 , pp. 733-748
    • Travis, W.D.1    Costabel, U.2    Hansell, D.M.3
  • 2
    • 79952717349 scopus 로고    scopus 로고
    • An official ATS/ERS/JRS/ALAT statement: Idiopathic pulmonary fibrosis: Evidence-based guidelines for diagnosis and management
    • Raghu G, Collard HR, Egan JJ, et al. An official ATS/ERS/JRS/ALAT statement: idiopathic pulmonary fibrosis: evidence-based guidelines for diagnosis and management. Am J Respir Crit Care Med 2011;183:788-824.
    • (2011) Am J Respir Crit Care Med , vol.183 , pp. 788-824
    • Raghu, G.1    Collard, H.R.2    Egan, J.J.3
  • 3
    • 48949091397 scopus 로고    scopus 로고
    • Diagnosis of usual interstitial pneumonia and distinction from other fibrosing interstitial lung diseases
    • Katzenstein AL, Mukhopadhyay S, Myers JL. Diagnosis of usual interstitial pneumonia and distinction from other fibrosing interstitial lung diseases. Hum Pathol 2008;39:1275-1294.
    • (2008) Hum Pathol , vol.39 , pp. 1275-1294
    • Katzenstein, A.L.1    Mukhopadhyay, S.2    Myers, J.L.3
  • 4
    • 0021288425 scopus 로고
    • Interstitial lung diseases of unknown cause. Disorders characterized by chronic inflammation of the lower respiratory tract (first of two parts)
    • Crystal RG, Bitterman PB, Rennard SI, et al. Interstitial lung diseases of unknown cause. Disorders characterized by chronic inflammation of the lower respiratory tract (first of two parts). N Engl J Med 1984;310:154-166.
    • (1984) N Engl J Med , vol.310 , pp. 154-166
    • Crystal, R.G.1    Bitterman, P.B.2    Rennard, S.I.3
  • 5
    • 0025019279 scopus 로고
    • Oxygen radical production by alveolar inflammatory cells in idiopathic pulmonary fibrosis
    • Strausz J, Müller-Quernheim J, Steppling H, et al. Oxygen radical production by alveolar inflammatory cells in idiopathic pulmonary fibrosis. Am Rev Respir Dis 1990;141:124-128.
    • (1990) Am Rev Respir Dis , vol.141 , pp. 124-128
    • Strausz, J.1    Müller-Quernheim, J.2    Steppling, H.3
  • 6
    • 0032812161 scopus 로고    scopus 로고
    • Systemic and pulmonary oxidative stress in idiopathic pulmonary fibrosis
    • Rahman I, Skwarska E, Henry M, et al. Systemic and pulmonary oxidative stress in idiopathic pulmonary fibrosis. Free Radic Biol Med 1999;27:60-68.
    • (1999) Free Radic Biol Med , vol.27 , pp. 60-68
    • Rahman, I.1    Skwarska, E.2    Henry, M.3
  • 7
    • 0019888660 scopus 로고
    • Activated bleomycin. A transient complex of drug, iron, and oxygen that degrades DNA
    • Burger RM, Peisach J, Horwitz SB. Activated bleomycin. A transient complex of drug, iron, and oxygen that degrades DNA. J Biol Chem 1981;256:11636-11644.
    • (1981) J Biol Chem , vol.256 , pp. 11636-11644
    • Burger, R.M.1    Peisach, J.2    Horwitz, S.B.3
  • 8
    • 0023839686 scopus 로고
    • Effect of iron deficiency on bleomycin-induced lung fibrosis in the hamster
    • Chandler DB, Barton JC, Briggs DD 3rd, et al. Effect of iron deficiency on bleomycin-induced lung fibrosis in the hamster. Am Rev Respir Dis 1988;137:85-89.
    • (1988) Am Rev Respir Dis , vol.137 , pp. 85-89
    • Chandler, D.B.1    Barton, J.C.2    Briggs, D.D.3
  • 9
    • 27944444527 scopus 로고    scopus 로고
    • N-acetylcysteine and deferoxamine reduce pulmonary oxidative stress and inflammation in rats after coal dust exposure
    • Pinho RA, Silveira PC, Silva LA, et al. N-acetylcysteine and deferoxamine reduce pulmonary oxidative stress and inflammation in rats after coal dust exposure. Environ Res 2005;99:355-360.
    • (2005) Environ Res , vol.99 , pp. 355-360
    • Pinho, R.A.1    Silveira, P.C.2    Silva, L.A.3
  • 10
    • 77954637782 scopus 로고    scopus 로고
    • Iron deposition and increased alveolar septal capillary density in nonfibrotic lung tissue are associated with pulmonary hypertension in idiopathic pulmonary fibrosis
    • Kim KH, Maldonado F, Ryu JH, et al. Iron deposition and increased alveolar septal capillary density in nonfibrotic lung tissue are associated with pulmonary hypertension in idiopathic pulmonary fibrosis. Respir Res 2010;11:37.
    • (2010) Respir Res , vol.11 , pp. 37
    • Kim, K.H.1    Maldonado, F.2    Ryu, J.H.3
  • 11
    • 84900533687 scopus 로고    scopus 로고
    • Iron laden macrophages in idiopathic pulmonary fibrosis: The telltale of occult alveolar hemorrhage?
    • Puxeddu E, Comandini A, Cavalli F, et al. Iron laden macrophages in idiopathic pulmonary fibrosis: the telltale of occult alveolar hemorrhage? Pulm Pharmacol Ther 2014;28:35-40.
    • (2014) Pulm Pharmacol Ther , vol.28 , pp. 35-40
    • Puxeddu, E.1    Comandini, A.2    Cavalli, F.3
  • 12
    • 0025157647 scopus 로고
    • The pathology of hepatic iron overload: A free radical-mediated process?
    • Bacon BR, Britton RS. The pathology of hepatic iron overload: a free radical-mediated process? Hepatology 1990;11:127-137.
    • (1990) Hepatology , vol.11 , pp. 127-137
    • Bacon, B.R.1    Britton, R.S.2
  • 13
    • 13144282684 scopus 로고    scopus 로고
    • The hemochromatosis gene product complexes with the transferrin receptor and lowers its affinity for ligand binding
    • Feder JN, Penny DM, Irrinki A, et al. The hemochromatosis gene product complexes with the transferrin receptor and lowers its affinity for ligand binding. Proc Natl Acad Sci USA 1998;95:1472-1477.
    • (1998) Proc Natl Acad Sci USA , vol.95 , pp. 1472-1477
    • Feder, J.N.1    Penny, D.M.2    Irrinki, A.3
  • 14
    • 0037132786 scopus 로고    scopus 로고
    • Penetrance of 845G→A (C282Y) HFE hereditary haemochromatosis mutation in the USA
    • Beutler E, Felitti VJ, Koziol JA, et al. Penetrance of 845G→A (C282Y) HFE hereditary haemochromatosis mutation in the USA. Lancet 2002;359:211-218.
    • (2002) Lancet , vol.359 , pp. 211-218
    • Beutler, E.1    Felitti, V.J.2    Koziol, J.A.3
  • 15
    • 10844258104 scopus 로고    scopus 로고
    • Hepcidin regulates cellular iron efflux by binding to ferroportin and inducing its internalization
    • Nemeth E, Tuttle MS, Powelson J, et al. Hepcidin regulates cellular iron efflux by binding to ferroportin and inducing its internalization. Science 2004;306:2090-2093.
    • (2004) Science , vol.306 , pp. 2090-2093
    • Nemeth, E.1    Tuttle, M.S.2    Powelson, J.3
  • 16
    • 17944380796 scopus 로고    scopus 로고
    • Autosomal-dominant hemochromatosis is associated with a mutation in the ferroportin (SLC11A3) gene
    • Montosi G, Donovan A, Totaro A, et al. Autosomal-dominant hemochromatosis is associated with a mutation in the ferroportin (SLC11A3) gene. J Clin Invest 2001;108:619-623.
    • (2001) J Clin Invest , vol.108 , pp. 619-623
    • Montosi, G.1    Donovan, A.2    Totaro, A.3
  • 17
    • 9144248397 scopus 로고    scopus 로고
    • Contribution of the H63D mutation in HFE to murine hereditary hemochromatosis
    • Tomatsu S, Orii KO, Fleming RE, et al. Contribution of the H63D mutation in HFE to murine hereditary hemochromatosis. Proc Natl Acad Sci USA 2003;100:15788-15793.
    • (2003) Proc Natl Acad Sci USA , vol.100 , pp. 15788-15793
    • Tomatsu, S.1    Orii, K.O.2    Fleming, R.E.3
  • 18
    • 0037366790 scopus 로고    scopus 로고
    • A population-based study of the effect of the HFE C282Y and H63D mutations on iron metabolism
    • Njajou OT, Houwing-Duistermaat JJ, Osborne RH, et al. A population-based study of the effect of the HFE C282Y and H63D mutations on iron metabolism. Eur J Hum Genet 2003;11:225-231.
    • (2003) Eur J Hum Genet , vol.11 , pp. 225-231
    • Njajou, O.T.1    Houwing-Duistermaat, J.J.2    Osborne, R.H.3
  • 20
    • 84876818198 scopus 로고    scopus 로고
    • Hfe mutations and iron overload in patients with alcoholic liver disease
    • Costa-Matos L, Batista P, Monteiro N, et al. Hfe mutations and iron overload in patients with alcoholic liver disease. Arq Gastroenterol 2013;50:35-41.
    • (2013) Arq Gastroenterol , vol.50 , pp. 35-41
    • Costa-Matos, L.1    Batista, P.2    Monteiro, N.3
  • 21
    • 0037336495 scopus 로고    scopus 로고
    • HFE mutations and chronic hepatitis C: H63D and C282Y heterozygosity are independent risk factors for liver fibrosis and cirrhosis
    • Erhardt A, Maschner-Olberg A, Mellenthin C, et al. HFE mutations and chronic hepatitis C: H63D and C282Y heterozygosity are independent risk factors for liver fibrosis and cirrhosis. J Hepatol 2003;38:335-342.
    • (2003) J Hepatol , vol.38 , pp. 335-342
    • Erhardt, A.1    Maschner-Olberg, A.2    Mellenthin, C.3
  • 22
    • 0025902388 scopus 로고
    • Lower respiratory tract iron burden is increased in association with cigarette smoking
    • Thompson AB, Bohling T, Heires A, et al. Lower respiratory tract iron burden is increased in association with cigarette smoking. J Lab Clin Med 1991;117:493-499.
    • (1991) J Lab Clin Med , vol.117 , pp. 493-499
    • Thompson, A.B.1    Bohling, T.2    Heires, A.3
  • 23
    • 30344471883 scopus 로고    scopus 로고
    • Clinical and pathologic features of familial interstitial pneumonia
    • Steele MP, Speer MC, Loyd JE, et al. Clinical and pathologic features of familial interstitial pneumonia. Am J Respir Crit Care Med 2005;172:1146-1152.
    • (2005) Am J Respir Crit Care Med , vol.172 , pp. 1146-1152
    • Steele, M.P.1    Speer, M.C.2    Loyd, J.E.3
  • 24
    • 84860621394 scopus 로고    scopus 로고
    • An official American Thoracic Society clinical practice guideline: The clinical utility of bronchoalveolar lavage cellular analysis in interstitial lung disease
    • Meyer KC, Raghu G, Baughman RP, et al. An official American Thoracic Society clinical practice guideline: the clinical utility of bronchoalveolar lavage cellular analysis in interstitial lung disease. Am J Respir Crit Care Med 2012;185:1004-1014.
    • (2012) Am J Respir Crit Care Med , vol.185 , pp. 1004-1014
    • Meyer, K.C.1    Raghu, G.2    Baughman, R.P.3
  • 25
    • 0016773243 scopus 로고
    • Occult pulmonary haemorrhage in leukaemia
    • Golde DW, Drew WL, Klein HZ, et al. Occult pulmonary haemorrhage in leukaemia. Br Med J 1975;2:166-168.
    • (1975) Br Med J , vol.2 , pp. 166-168
    • Golde, D.W.1    Drew, W.L.2    Klein, H.Z.3
  • 26
    • 0025914732 scopus 로고
    • Simultaneous separation of malondialdehyde, ascorbic acid, and adenine nucleotide derivatives from biological samples by ion-pairing high-performance liquid chromatography
    • Lazzarino G, Di Pierro D, Tavazzi B, et al. Simultaneous separation of malondialdehyde, ascorbic acid, and adenine nucleotide derivatives from biological samples by ion-pairing high-performance liquid chromatography. Anal Biochem 1991;197:191-196.
    • (1991) Anal Biochem , vol.197 , pp. 191-196
    • Lazzarino, G.1    Di Pierro, D.2    Tavazzi, B.3
  • 27
    • 0021288842 scopus 로고
    • Detection of malonaldehyde by high-performance liquid chromatography
    • Esterbauer H, Lang J, Zadravec S, et al. Detection of malonaldehyde by high-performance liquid chromatography. Methods Enzymol 1984;105:319-328.
    • (1984) Methods Enzymol , vol.105 , pp. 319-328
    • Esterbauer, H.1    Lang, J.2    Zadravec, S.3
  • 28
    • 0020625894 scopus 로고
    • Flow cytometric studies of oxidative product formation by neutrophils: A graded response to membrane stimulation
    • Bass DA, Parce JW, Dechatelet LR, et al. Flow cytometric studies of oxidative product formation by neutrophils: a graded response to membrane stimulation. J Immunol 1983;130:1910-1917.
    • (1983) J Immunol , vol.130 , pp. 1910-1917
    • Bass, D.A.1    Parce, J.W.2    Dechatelet, L.R.3
  • 29
    • 62349122681 scopus 로고    scopus 로고
    • STrengthening the REporting of Genetic Association studies (STREGA) - An extension of the STROBE statement
    • Little J, Higgins JP, Ioannidis JP, et al. STrengthening the REporting of Genetic Association studies (STREGA) - an extension of the STROBE statement. Eur J Clin Invest 2009;39:247-266.
    • (2009) Eur J Clin Invest , vol.39 , pp. 247-266
    • Little, J.1    Higgins, J.P.2    Ioannidis, J.P.3
  • 30
    • 79551613913 scopus 로고    scopus 로고
    • Lane-Hamilton syndrome: Ferritin protects lung macrophages against iron and oxidation
    • Persson HL, Vainikka LK, Eriksson HB, et al. Lane-Hamilton syndrome: ferritin protects lung macrophages against iron and oxidation. Chest 2011;139:361-367.
    • (2011) Chest , vol.139 , pp. 361-367
    • Persson, H.L.1    Vainikka, L.K.2    Eriksson, H.B.3
  • 32
    • 69249117384 scopus 로고    scopus 로고
    • Haemosiderin-laden macrophages in the bronchoalveolar lavage fluid of patients with diffuse alveolar damage
    • Maldonado F, Parambil JG, Yi ES, et al. Haemosiderin-laden macrophages in the bronchoalveolar lavage fluid of patients with diffuse alveolar damage. Eur Respir J 2009;33:1361-1366.
    • (2009) Eur Respir J , vol.33 , pp. 1361-1366
    • Maldonado, F.1    Parambil, J.G.2    Yi, E.S.3
  • 33
    • 33749559426 scopus 로고    scopus 로고
    • Quantification of siderophages in bronchoalveolar fluid in transfusional and primary pulmonary hemosiderosis
    • Priftis KN, Anthracopoulos MB, Tsakanika C, et al. Quantification of siderophages in bronchoalveolar fluid in transfusional and primary pulmonary hemosiderosis. Pediatr Pulmonol 2006;41:972-977.
    • (2006) Pediatr Pulmonol , vol.41 , pp. 972-977
    • Priftis, K.N.1    Anthracopoulos, M.B.2    Tsakanika, C.3
  • 34
    • 0142178315 scopus 로고    scopus 로고
    • Beta-thalassemia major: Thin-section CT features and correlation with pulmonary function and iron overload
    • Khong PL, Chan GC, Lee SL, et al. Beta-thalassemia major: thin-section CT features and correlation with pulmonary function and iron overload. Radiology 2003;229:507-512.
    • (2003) Radiology , vol.229 , pp. 507-512
    • Khong, P.L.1    Chan, G.C.2    Lee, S.L.3
  • 35
    • 0036368711 scopus 로고    scopus 로고
    • Pulmonary iron overload in thalassemia major presenting as small airway disease
    • Ooi GC, Khong PL, Lam WK, et al. Pulmonary iron overload in thalassemia major presenting as small airway disease. Acta Haematol 2002;108:43-46.
    • (2002) Acta Haematol , vol.108 , pp. 43-46
    • Ooi, G.C.1    Khong, P.L.2    Lam, W.K.3
  • 36
    • 77955270673 scopus 로고    scopus 로고
    • Changes in parameters of oxidative stress and free iron biomarkers during treatment with deferasirox in iron-overloaded patients with myelodysplastic syndromes
    • Ghoti H, Fibach E, Merkel D, et al. Changes in parameters of oxidative stress and free iron biomarkers during treatment with deferasirox in iron-overloaded patients with myelodysplastic syndromes. Haematologica 2010;95:1433-1434.
    • (2010) Haematologica , vol.95 , pp. 1433-1434
    • Ghoti, H.1    Fibach, E.2    Merkel, D.3
  • 37
    • 0034663835 scopus 로고    scopus 로고
    • Occupational and environmental risk factors for idiopathic pulmonary fibrosis: A multicenter case-control study
    • Baumgartner KB, Samet JM, Coultas DB, et al. Occupational and environmental risk factors for idiopathic pulmonary fibrosis: a multicenter case-control study. Am J Epidemiol 2000;152:307-315.
    • (2000) Am J Epidemiol , vol.152 , pp. 307-315
    • Baumgartner, K.B.1    Samet, J.M.2    Coultas, D.B.3
  • 38
    • 3042700097 scopus 로고    scopus 로고
    • Mortality in relation to smoking: 50 years' observations on male British doctors
    • Doll R, Peto R, Boreham J, et al. Mortality in relation to smoking: 50 years' observations on male British doctors. BMJ 2004;328:1519.
    • (2004) BMJ , vol.328 , pp. 1519
    • Doll, R.1    Peto, R.2    Boreham, J.3
  • 39
    • 34547481379 scopus 로고    scopus 로고
    • An open population screening study for HFE gene major mutations proves the low prevalence of C282Y mutation in Central Italy
    • Floreani A, Rosa Rizzotto E, Basso D, et al. An open population screening study for HFE gene major mutations proves the low prevalence of C282Y mutation in Central Italy. Aliment Pharmacol Ther 2007;26:577-586.
    • (2007) Aliment Pharmacol Ther , vol.26 , pp. 577-586
    • Floreani, A.1    Rosa Rizzotto, E.2    Basso, D.3
  • 40
    • 84922179143 scopus 로고    scopus 로고
    • Idiopathic pulmonary fibrosis (IPF) incidence and prevalence in Italy
    • Agabiti N, Porretta MA, Bauleo L, et al. Idiopathic pulmonary fibrosis (IPF) incidence and prevalence in Italy. Sarcoidosis Vasc Diffuse Lung Dis 2014;31:191-197.
    • (2014) Sarcoidosis Vasc Diffuse Lung Dis , vol.31 , pp. 191-197
    • Agabiti, N.1    Porretta, M.A.2    Bauleo, L.3
  • 41
    • 79956343961 scopus 로고    scopus 로고
    • The rising incidence of idiopathic pulmonary fibrosis in the UK
    • Navaratnam V, Fleming KM, West J, et al. The rising incidence of idiopathic pulmonary fibrosis in the UK. Thorax 2011;66:462-467.
    • (2011) Thorax , vol.66 , pp. 462-467
    • Navaratnam, V.1    Fleming, K.M.2    West, J.3
  • 42
    • 52749083873 scopus 로고    scopus 로고
    • Telomere shortening in familial and sporadic pulmonary fibrosis
    • Cronkhite JT, Xing C, Raghu G, et al. Telomere shortening in familial and sporadic pulmonary fibrosis. Am J Respir Crit Care Med 2008;178:729-737.
    • (2008) Am J Respir Crit Care Med , vol.178 , pp. 729-737
    • Cronkhite, J.T.1    Xing, C.2    Raghu, G.3
  • 43
    • 33644861968 scopus 로고    scopus 로고
    • Telomere shortening in smokers with and without COPD
    • Morlá M, Busquets X, Pons J, et al. Telomere shortening in smokers with and without COPD. Eur Respir J 2006;27:525-528.
    • (2006) Eur Respir J , vol.27 , pp. 525-528
    • Morlá, M.1    Busquets, X.2    Pons, J.3


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