The development of PARP inhibitors in ovarian cancer: From bench to bedside

British Journal of Cancer

Volumn 113, Issue S1, 2015, Pages S3-S9

  Drew, Yvette ^a,b  

^a NEWCASTLE UNIVERSITY   (United Kingdom)

^b FREEMAN HOSPITAL   (United Kingdom)

Author keywords

Olaparib; ovarian cancer; PARP

Indexed keywords

3 AMINOBENZAMIDE; BRCA PROTEIN; BRCA1 PROTEIN; DNA; NICOTINAMIDE ADENINE DINUCLEOTIDE ADENOSINE DIPHOSPHATE RIBOSYLTRANSFERASE; NICOTINAMIDE ADENINE DINUCLEOTIDE ADENOSINE DIPHOSPHATE RIBOSYLTRANSFERASE INHIBITOR; NIRAPARIB; OLAPARIB; PLATINUM DERIVATIVE; RUCAPARIB; TALAZOPARIB; TUMOR SUPPRESSOR PROTEIN; UNCLASSIFIED DRUG; VASCULOTROPIN INHIBITOR; VELIPARIB;

CANCER PATIENT; CELL PROLIFERATION; CLINICAL TRIAL (TOPIC); CYTOTOXICITY; DNA DAMAGE; DNA END JOINING REPAIR; DNA REPAIR; DRUG APPROVAL; DRUG DESIGN; DRUG EFFICACY; GENE MUTATION; GERMLINE MUTATION; HUMAN; IN VITRO STUDY; IN VIVO STUDY; LETHALITY; LICENSING; NONHUMAN; OVARY CANCER; PERSONALIZED MEDICINE; PRIORITY JOURNAL; PROGRESSION FREE SURVIVAL; PROTEIN SYNTHESIS; RECOMBINATION REPAIR; REVIEW; SOMATIC MUTATION; TUMOR SUPPRESSOR GENE; WILD TYPE; FEMALE; METABOLISM; OVARIAN NEOPLASMS;

FEMALE; HUMANS; OVARIAN NEOPLASMS; POLY(ADP-RIBOSE) POLYMERASE INHIBITORS;

EID: 84950159003     PISSN: 00070920     EISSN: 15321827     Source Type: Journal    
DOI: 10.1038/bjc.2015.394     Document Type: Review

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