Novel treatment strategies in triple-negative breast cancer: specific role of poly(adenosine diphosphate-ribose) polymerase inhibition

Pharmacogenomics and Personalized Medicine

Volumn 7, Issue , 2014, Pages 307-316

  Audeh, M William ^a  

^a CEDARS SINAI MEDICAL CENTER   (United States)

Author keywords

PARP; PARP inhibitors; Triple negative breast cancer

Indexed keywords

BIOLOGICAL MARKER; BRCA1 PROTEIN; BRCA2 PROTEIN; CARBOPLATIN; CISPLATIN; EPIDERMAL GROWTH FACTOR RECEPTOR 2; ESTROGEN RECEPTOR; GEMCITABINE; INIPARIB; NICOTINAMIDE ADENINE DINUCLEOTIDE ADENOSINE DIPHOSPHATE RIBOSYLTRANSFERASE; NICOTINAMIDE ADENINE DINUCLEOTIDE ADENOSINE DIPHOSPHATE RIBOSYLTRANSFERASE INHIBITOR; NIRAPARIB; OLAPARIB; PACLITAXEL; PROGESTERONE RECEPTOR; RUCAPARIB; TALAZOPARIB; TEMOZOLOMIDE; VELIPARIB;

ADJUVANT THERAPY; BRCA GENE; BREAST CANCER; BREAST METASTASIS; DNA REPAIR; DOSE RESPONSE; DOUBLE STRANDED DNA BREAK; DRUG MECHANISM; ENZYME INHIBITION; GENE; GENE MUTATION; GENOMIC INSTABILITY; HOMOLOGOUS REPAIR DEFICIENCY; HUMAN; PHASE 1 CLINICAL TRIAL (TOPIC); PHASE 2 CLINICAL TRIAL (TOPIC); PHASE 3 CLINICAL TRIAL (TOPIC); PROTEIN TARGETING; RANDOMIZED CONTROLLED TRIAL (TOPIC); REVIEW; SINGLE DRUG DOSE; TRIPLE NEGATIVE BREAST CANCER;

EID: 84908134469     PISSN: None     EISSN: 11787066     Source Type: Journal    
DOI: 10.2147/PGPM.S39765     Document Type: Review

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