Changes in autophagy, proteasome activity and metabolism to determine a specific signature for acute and chronic senescent mesenchymal stromal cells

Oncotarget

Volumn 6, Issue 37, 2015, Pages 39457-39468

  Capasso, Stefania ^b   Alessio, Nicola ^b   Squillaro, Tiziana ^b   Di Bernardo, Giovanni ^b   Melone, Mariarosa A ^b,c   Cipollaro, Marilena ^b   Peluso, Gianfranco ^c   Galderisi, Umberto ^a,b,c  

^a TEMPLE UNIVERSITY   (United States)

^b SECOND UNIVERSITY OF NAPLES   (Italy)

^c CNR   (Italy)

Author keywords

Autophagy; Gerotarget; Mesenchymal stem cells; Metabolism; Proteasome; Senescence

Indexed keywords

DOXORUBICIN; FATTY ACID DERIVATIVE; GLUCOSE; GLUTAMINE; PEROXIDE; PROTEASOME; ANTINEOPLASTIC ANTIBIOTIC; FATTY ACID;

ACUTE SENESCENT MESENCHYMAL STROMAL CELL; ADIPOCYTE; ARTICLE; AUTOPHAGY; BIOENERGY; BIOLOGICAL ACTIVITY; CARTILAGE CELL; CELL AGING; CELL DIFFERENTIATION; CELL DIVISION; CELL METABOLISM; CELL PROLIFERATION; CELL STRESS; CELL SUBPOPULATION; CHEMICAL STRESS; CHILD; CHRONIC SENESCENT MESENCHYMAL STROMAL CELL; CLASSIFICATION; CONTROLLED STUDY; ENZYME ACTIVITY; HOMEOSTASIS; HUMAN; HUMAN CELL; MESENCHYMAL STROMA CELL; OSTEOCYTE; OXIDATIVE STRESS; PHENOTYPE; PRESCHOOL CHILD; RADIATION DOSE; SCHOOL CHILD; X IRRADIATION; CELL CULTURE; DRUG EFFECTS; ENERGY METABOLISM; METABOLISM; PHYSIOLOGY; RADIATION RESPONSE; WESTERN BLOTTING; X RAY;

ANTIBIOTICS, ANTINEOPLASTIC; AUTOPHAGY; BLOTTING, WESTERN; CELL AGING; CELLS, CULTURED; CHILD; DOXORUBICIN; ENERGY METABOLISM; FATTY ACIDS; GLUCOSE; GLUTAMINE; HUMANS; MESENCHYMAL STROMAL CELLS; METABOLIC NETWORKS AND PATHWAYS; OXIDATIVE STRESS; PROTEASOME ENDOPEPTIDASE COMPLEX; X-RAYS;

EID: 84950155106     PISSN: None     EISSN: 19492553     Source Type: Journal    
DOI: 10.18632/oncotarget.6277     Document Type: Article

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