-
1
-
-
84884856342
-
Cas9 as a versatile tool for engineering biology
-
Mali, P. , Esvelt, K. M. and Church, G. M. (2013) Cas9 as a versatile tool for engineering biology. Nat. Methods, 10, 957-963.
-
(2013)
Nat. Methods
, vol.10
, pp. 957-963
-
-
Mali, P.1
Esvelt, K.M.2
Church, G.M.3
-
2
-
-
84950126700
-
Genome engineering using CRISPR-Cas9 system
-
Cong, L. and Zhang, F. (2014) Genome engineering using CRISPR-Cas9 system. Methods Mol. Biol. , 1239, 197-217.
-
(2014)
Methods Mol. Biol.
, vol.1239
, pp. 197-217
-
-
Cong, L.1
Zhang, F.2
-
3
-
-
84913594397
-
Genome editing. The new frontier of genome engineering with CRISPR-Cas9
-
Doudna, J. A. and Charpentier, E. (2014) Genome editing. The new frontier of genome engineering with CRISPR-Cas9. Science, 346, 1258096.
-
(2014)
Science
, vol.346
, pp. 1258096
-
-
Doudna, J.A.1
Charpentier, E.2
-
4
-
-
84876567971
-
RNA-programmed genome editing in human cells
-
Jinek, M. , East, A. , Cheng, A. , Lin, S. , Ma, E. and Doudna, J. (2013) RNA-programmed genome editing in human cells. Elife, 2, e00471.
-
(2013)
Elife
, vol.2
, pp. e00471
-
-
Jinek, M.1
East, A.2
Cheng, A.3
Lin, S.4
Ma, E.5
Doudna, J.6
-
5
-
-
84873729095
-
Multiplex genome engineering using CRISPR/Cas systems
-
Cong, L. , Ran, F. A. , Cox, D. , Lin, S. , Barretto, R. , Habib, N. , Hsu, P. D. , Wu, X. , Jiang, W. , Marraffini, L. A. et al. (2013) Multiplex genome engineering using CRISPR/Cas systems. Science, 339, 819-823.
-
(2013)
Science
, vol.339
, pp. 819-823
-
-
Cong, L.1
Ran, F.A.2
Cox, D.3
Lin, S.4
Barretto, R.5
Habib, N.6
Hsu, P.D.7
Wu, X.8
Jiang, W.9
Marraffini, L.A.10
-
6
-
-
84873734105
-
RNA-guided human genome engineering via Cas9
-
Mali, P. , Yang, L. , Esvelt, K. M. , Aach, J. , Guell, M. , DiCarlo, J. E. , Norville, J. E. and Church, G. M. (2013) RNA-guided human genome engineering via Cas9. Science, 339, 823-826.
-
(2013)
Science
, vol.339
, pp. 823-826
-
-
Mali, P.1
Yang, L.2
Esvelt, K.M.3
Aach, J.4
Guell, M.5
DiCarlo, J.E.6
Norville, J.E.7
Church, G.M.8
-
7
-
-
84892765883
-
Genome-scale CRISPR-Cas9 knockout screening in human cells
-
Shalem, O. , Sanjana, N. E. , Hartenian, E. , Shi, X. , Scott, D. A. , Mikkelsen, T. S. , Heckl, D. , Ebert, B. L. , Root, D. E. , Doench, J. G. et al. (2014) Genome-scale CRISPR-Cas9 knockout screening in human cells. Science, 343, 84-87.
-
(2014)
Science
, vol.343
, pp. 84-87
-
-
Shalem, O.1
Sanjana, N.E.2
Hartenian, E.3
Shi, X.4
Scott, D.A.5
Mikkelsen, T.S.6
Heckl, D.7
Ebert, B.L.8
Root, D.E.9
Doench, J.G.10
-
8
-
-
84892749369
-
Genetic screens in human cells using the CRISPR-Cas9 system
-
Wang, T. , Wei, J. J. , Sabatini, D. M. and Lander, E. S. (2014) Genetic screens in human cells using the CRISPR-Cas9 system. Science, 343, 80-84.
-
(2014)
Science
, vol.343
, pp. 80-84
-
-
Wang, T.1
Wei, J.J.2
Sabatini, D.M.3
Lander, E.S.4
-
9
-
-
84895528015
-
Isolation of single-base genome-edited human iPS cells without antibiotic selection
-
Miyaoka, Y. , Chan, A. H. , Judge, L. M. , Yoo, J. , Huang, M. , Nguyen, T. D. , Lizarraga, P. P. , So, P. L. and Conklin, B. R. (2014) Isolation of single-base genome-edited human iPS cells without antibiotic selection. Nat. Methods, 11, 291-293.
-
(2014)
Nat. Methods
, vol.11
, pp. 291-293
-
-
Miyaoka, Y.1
Chan, A.H.2
Judge, L.M.3
Yoo, J.4
Huang, M.5
Nguyen, T.D.6
Lizarraga, P.P.7
So, P.L.8
Conklin, B.R.9
-
10
-
-
84885157177
-
Optimization of scarless human stem cell genome editing
-
Yang, L. , Guell, M. , Byrne, S. , Yang, J. L. , De Los Angeles, A. , Mali, P. , Aach, J. , Kim-Kiselak, C. , Briggs, A. W. , Rios, X. et al. (2013) Optimization of scarless human stem cell genome editing. Nucleic Acids Res. , 41, 9049-9061.
-
(2013)
Nucleic Acids Res.
, vol.41
, pp. 9049-9061
-
-
Yang, L.1
Guell, M.2
Byrne, S.3
Yang, J.L.4
De Los Angeles, A.5
Mali, P.6
Aach, J.7
Kim-Kiselak, C.8
Briggs, A.W.9
Rios, X.10
-
11
-
-
84880570576
-
High-frequency off-target mutagenesis induced by CRISPR-Cas nucleases in human cells
-
Fu, Y. , Foden, J. A. , Khayter, C. , Maeder, M. L. , Reyon, D. , Joung, J. K. and Sander, J. D. (2013) High-frequency off-target mutagenesis induced by CRISPR-Cas nucleases in human cells. Nat. Biotechnol. , 31, 822-826.
-
(2013)
Nat. Biotechnol.
, vol.31
, pp. 822-826
-
-
Fu, Y.1
Foden, J.A.2
Khayter, C.3
Maeder, M.L.4
Reyon, D.5
Joung, J.K.6
Sander, J.D.7
-
12
-
-
0023491946
-
Genetic analysis of human hypoxanthine-guanine phosphoribosyltransferase deficiency
-
Silverman, L. J. , Kelley, W. N. and Palella, T. D. (1987) Genetic analysis of human hypoxanthine-guanine phosphoribosyltransferase deficiency. Enzyme, 38, 36-44.
-
(1987)
Enzyme
, vol.38
, pp. 36-44
-
-
Silverman, L.J.1
Kelley, W.N.2
Palella, T.D.3
-
13
-
-
0021152677
-
Cytotoxic and cytodifferentiative components of 6-thioguanine resistance in HL-60 cells containing acquired double minute chromosomes
-
Gallagher, R. E. , Ferrari, A. C. , Zulich, A. W. , Yen, R. W. and Testa, J. R. (1984) Cytotoxic and cytodifferentiative components of 6-thioguanine resistance in HL-60 cells containing acquired double minute chromosomes. Cancer Res. , 44, 2642-2653.
-
(1984)
Cancer Res.
, vol.44
, pp. 2642-2653
-
-
Gallagher, R.E.1
Ferrari, A.C.2
Zulich, A.W.3
Yen, R.W.4
Testa, J.R.5
-
14
-
-
0025040536
-
Characterization of the DNA damage in 6-thioguanine-treated cells
-
Pan, B. F. and Nelson, J. A. (1990) Characterization of the DNA damage in 6-thioguanine-treated cells. Biochem. Pharmacol. , 40, 1063-1069.
-
(1990)
Biochem. Pharmacol.
, vol.40
, pp. 1063-1069
-
-
Pan, B.F.1
Nelson, J.A.2
-
15
-
-
0029822592
-
Role of postreplicative DNA mismatch repair in the cytotoxic action of thioguanine
-
Swann, P. F. , Waters, T. R. , Moulton, D. C. , Xu, Y. Z. , Zheng, Q. , Edwards, M. and Mace, R. (1996) Role of postreplicative DNA mismatch repair in the cytotoxic action of thioguanine. Science, 273, 1109-1111.
-
(1996)
Science
, vol.273
, pp. 1109-1111
-
-
Swann, P.F.1
Waters, T.R.2
Moulton, D.C.3
Xu, Y.Z.4
Zheng, Q.5
Edwards, M.6
Mace, R.7
-
16
-
-
0347951257
-
Karyotypic complexity of the NCI-60 drug-screening panel
-
Roschke, A. V. , Tonon, G. , Gehlhaus, K. S. , McTyre, N. , Bussey, K. J. , Lababidi, S. , Scudiero, D. A. , Weinstein, J. N. and Kirsch, I. R. (2003) Karyotypic complexity of the NCI-60 drug-screening panel. Cancer Res. , 63, 8634-8647.
-
(2003)
Cancer Res.
, vol.63
, pp. 8634-8647
-
-
Roschke, A.V.1
Tonon, G.2
Gehlhaus, K.S.3
McTyre, N.4
Bussey, K.J.5
Lababidi, S.6
Scudiero, D.A.7
Weinstein, J.N.8
Kirsch, I.R.9
-
17
-
-
84884591984
-
Genetic instability: Tipping the balance
-
Janssen, A. and Medema, R. H. (2013) Genetic instability: tipping the balance. Oncogene, 32, 4459-4470.
-
(2013)
Oncogene
, vol.32
, pp. 4459-4470
-
-
Janssen, A.1
Medema, R.H.2
-
18
-
-
0036085460
-
Cellular roles of DNA topoisomerases: A molecular perspective
-
Wang, J. C. (2002) Cellular roles of DNA topoisomerases: a molecular perspective. Nat. Rev. Mol. Cell. Biol. , 3, 430-440.
-
(2002)
Nat. Rev. Mol. Cell. Biol.
, vol.3
, pp. 430-440
-
-
Wang, J.C.1
-
19
-
-
0028097392
-
Analysis of in vivo mutation in exon 8 of the rat hprt gene
-
Mittelstaedt, R. A. and Heflich, R. H. (1994) Analysis of in vivo mutation in exon 8 of the rat hprt gene. Mutat. Res. , 311, 139-148.
-
(1994)
Mutat. Res.
, vol.311
, pp. 139-148
-
-
Mittelstaedt, R.A.1
Heflich, R.H.2
-
20
-
-
0020960968
-
Hypoxanthine-guanine phosphoribosyltransferase deficiency. The molecular basis of the clinical syndromes
-
Wilson, J. M. , Young, A. B. and Kelley, W. N. (1983) Hypoxanthine-guanine phosphoribosyltransferase deficiency. The molecular basis of the clinical syndromes. N. Engl. J. Med. , 309, 900-910.
-
(1983)
N. Engl. J. Med.
, vol.309
, pp. 900-910
-
-
Wilson, J.M.1
Young, A.B.2
Kelley, W.N.3
-
21
-
-
0033538461
-
Identification and expression of the TREX1 and TREX2 cDNA sequences encoding mammalian 3->5- exonucleases
-
Mazur, D. J. and Perrino, F. W. (1999) Identification and expression of the TREX1 and TREX2 cDNA sequences encoding mammalian 3->5- exonucleases. J. Biol. Chem. , 274, 19655-19660.
-
(1999)
J. Biol. Chem.
, vol.274
, pp. 19655-19660
-
-
Mazur, D.J.1
Perrino, F.W.2
-
22
-
-
0032532682
-
Human exonuclease i interacts with the mismatch repair protein hMSH2
-
Schmutte, C. , Marinescu, R. C. , Sadoff, M. M. , Guerrette, S. , Overhauser, J. and Fishel, R. (1998) Human exonuclease I interacts with the mismatch repair protein hMSH2. Cancer Res. , 58, 4537-4542.
-
(1998)
Cancer Res.
, vol.58
, pp. 4537-4542
-
-
Schmutte, C.1
Marinescu, R.C.2
Sadoff, M.M.3
Guerrette, S.4
Overhauser, J.5
Fishel, R.6
-
23
-
-
0032529299
-
Hex1: A new human Rad2 nuclease family member with homology to yeast exonuclease 1
-
Wilson, D. M. 3rd, Carney, J. P. , Coleman, M. A. , Adamson, A. W. , Christensen, M. and Lamerdin, J. E. (1998) Hex1: a new human Rad2 nuclease family member with homology to yeast exonuclease 1. Nucleic Acids Res. , 26, 3762-3768.
-
(1998)
Nucleic Acids Res.
, vol.26
, pp. 3762-3768
-
-
Wilson, D.M.1
Carney, J.P.2
Coleman, M.A.3
Adamson, A.W.4
Christensen, M.5
Lamerdin, J.E.6
-
24
-
-
0034621854
-
Frequent chromosomal translocations induced by DNA double-strand breaks
-
Richardson, C. and Jasin, M. (2000) Frequent chromosomal translocations induced by DNA double-strand breaks. Nature, 405, 697-700.
-
(2000)
Nature
, vol.405
, pp. 697-700
-
-
Richardson, C.1
Jasin, M.2
-
25
-
-
84862778059
-
Spatial organization of the mouse genome and its role in recurrent chromosomal translocations
-
Zhang, Y. , McCord, R. P. , Ho, Y. J. , Lajoie, B. R. , Hildebrand, D. G. , Simon, A. C. , Becker, M. S. , Alt, F. W. and Dekker, J. (2012) Spatial organization of the mouse genome and its role in recurrent chromosomal translocations. Cell, 148, 908-921.
-
(2012)
Cell
, vol.148
, pp. 908-921
-
-
Zhang, Y.1
McCord, R.P.2
Ho, Y.J.3
Lajoie, B.R.4
Hildebrand, D.G.5
Simon, A.C.6
Becker, M.S.7
Alt, F.W.8
Dekker, J.9
-
26
-
-
84885091153
-
The housekeeping gene hypoxanthine guanine phosphoribosyltransferase (HPRT) regulates multiple developmental and metabolic pathways of murine embryonic stem cell neuronal differentiation
-
Kang, T. H. , Park, Y. , Bader, J. S. and Friedmann, T. (2013) The housekeeping gene hypoxanthine guanine phosphoribosyltransferase (HPRT) regulates multiple developmental and metabolic pathways of murine embryonic stem cell neuronal differentiation. PLoS One, 8, e74967.
-
(2013)
PLoS One
, vol.8
, pp. e74967
-
-
Kang, T.H.1
Park, Y.2
Bader, J.S.3
Friedmann, T.4
-
27
-
-
84905665662
-
A co-CRISPR strategy for efficient genome editing in Caenorhabditis elegans
-
Kim, H. , Ishidate, T. , Ghanta, K. S. , Seth, M. , Conte, D. , Jr. , Shirayama, M. and Mello, C. C. (2014) A co-CRISPR strategy for efficient genome editing in Caenorhabditis elegans. Genetics, 197, 1069-1080.
-
(2014)
Genetics
, vol.197
, pp. 1069-1080
-
-
Kim, H.1
Ishidate, T.2
Ghanta, K.S.3
Seth, M.4
Conte, D.5
Shirayama, M.6
Mello, C.C.7
-
28
-
-
84964313213
-
Efficient marker-free recovery of custom genetic modifications with CRISPR/Cas9 in Caenorhabditis elegans
-
Arribere, J. A. , Bell, R. T. , Fu, B. X. , Artiles, K. L. , Hartman, P. S. and Fire, A. Z. (2014) Efficient marker-free recovery of custom genetic modifications with CRISPR/Cas9 in Caenorhabditis elegans. Genetics, 198, 837-846.
-
(2014)
Genetics
, vol.198
, pp. 837-846
-
-
Arribere, J.A.1
Bell, R.T.2
Fu, B.X.3
Artiles, K.L.4
Hartman, P.S.5
Fire, A.Z.6
-
29
-
-
84926451490
-
Rapid and precise engineering of the Caenorhabditis elegans genome with lethal mutation co-conversion and inactivation of NHEJ repair
-
Ward, J. D. (2015) Rapid and precise engineering of the Caenorhabditis elegans genome with lethal mutation co-conversion and inactivation of NHEJ repair. Genetics, 199, 363-377.
-
(2015)
Genetics
, vol.199
, pp. 363-377
-
-
Ward, J.D.1
|