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Volumn 8, Issue 10, 2013, Pages

The Housekeeping Gene Hypoxanthine Guanine Phosphoribosyltransferase (HPRT) Regulates Multiple Developmental and Metabolic Pathways of Murine Embryonic Stem Cell Neuronal Differentiation

Author keywords

[No Author keywords available]

Indexed keywords

DNA; GLYCAN; HYPOXANTHINE PHOSPHORIBOSYLTRANSFERASE; REGULATOR PROTEIN; RNA; SPHINGOLIPID; SULFUR; TRANSCRIPTION FACTOR SOX2;

EID: 84885091153     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0074967     Document Type: Article
Times cited : (44)

References (56)
  • 1
    • 0000544518 scopus 로고    scopus 로고
    • Lesch-Nyhan Disease and its Variants
    • Scriver, Beaudet, Sly and Valle (eds.), McGraw Hill
    • Jinnah HA, Friedmann T (2000) Lesch-Nyhan Disease and its Variants. Metabolic and Molecular Bases of Inherited Disease Scriver, Beaudet, Sly and Valle (eds.), McGraw Hill 2537-2570.
    • (2000) Metabolic and Molecular Bases of Inherited Disease , pp. 2537-2570
    • Jinnah, H.A.1    Friedmann, T.2
  • 2
    • 0032127325 scopus 로고    scopus 로고
    • Impaired differentiation of HPRT-deficient dopaminergic neurons: a possible mechanism underlying neuronal dysfunction in Lesch-Nyhan syndrome
    • Yeh J, Zheng S, Howard BD, (1998) Impaired differentiation of HPRT-deficient dopaminergic neurons: a possible mechanism underlying neuronal dysfunction in Lesch-Nyhan syndrome. J Neurosci Res 53(1): 78-85.
    • (1998) J Neurosci Res , vol.53 , Issue.1 , pp. 78-85
    • Yeh, J.1    Zheng, S.2    Howard, B.D.3
  • 3
    • 0034180939 scopus 로고    scopus 로고
    • Characterization of the dopamine defect in primary cultures of dopaminergic neurons from hypoxanthine phosphoribosyltransferase knockout mice
    • Smith DW, Friedmann T, (2000) Characterization of the dopamine defect in primary cultures of dopaminergic neurons from hypoxanthine phosphoribosyltransferase knockout mice. Mol Ther 1: 486-491.
    • (2000) Mol Ther , vol.1 , pp. 486-491
    • Smith, D.W.1    Friedmann, T.2
  • 4
    • 67249161053 scopus 로고    scopus 로고
    • Hypoxanthine-guanine phosphoribosyl transferase regulates early developmental programming of dopamine neurons: implications for Lesch-Nyhan disease pathogenesis
    • Ceballos-Picot I, Mockel L, Potier MD, Dauphinot L, Shirley TL, et al. (2009) Hypoxanthine-guanine phosphoribosyl transferase regulates early developmental programming of dopamine neurons: implications for Lesch-Nyhan disease pathogenesis. Hum Mol Genet 18: 2317-2327.
    • (2009) Hum Mol Genet , vol.18 , pp. 2317-2327
    • Ceballos-Picot, I.1    Mockel, L.2    Potier, M.D.3    Dauphinot, L.4    Shirley, T.L.5
  • 5
    • 74149090144 scopus 로고    scopus 로고
    • Deficiency of the housekeeping gene hypoxanthine-guanine phosphoribosyltransferase (HPRT) dysregulates neurogenesis
    • Guibinga GH, Hsu S, Friedmann T, (2010) Deficiency of the housekeeping gene hypoxanthine-guanine phosphoribosyltransferase (HPRT) dysregulates neurogenesis. Mol Ther 18: 54-62.
    • (2010) Mol Ther , vol.18 , pp. 54-62
    • Guibinga, G.H.1    Hsu, S.2    Friedmann, T.3
  • 6
    • 79551572037 scopus 로고    scopus 로고
    • HPRT deficiency coordinately dysregulates canonical WNT and presenilin-1 signaling: a neuro-developmental regulatory role for a housekeeping gene?
    • doi:10.1371/journal.pone.oo16572
    • Kang TH, Guibinga G, Jinnah HA, Friedmann T, (2011) HPRT deficiency coordinately dysregulates canonical WNT and presenilin-1 signaling: a neuro-developmental regulatory role for a housekeeping gene? PLoS One 6(1): e16572 doi: 10.1371/journal.pone.oo16572.
    • (2011) PLoS One , vol.6 , Issue.1
    • Kang, T.H.1    Guibinga, G.2    Jinnah, H.A.3    Friedmann, T.4
  • 7
    • 84863230376 scopus 로고    scopus 로고
    • Purinergic signaling in human pluripotent cells is regulated by the housekeeping gene hypoxanthine guanine phosphoribosyltransferase
    • Mastrangelo L, Kim JE, Miyanohara A, Kang TH, Friedmann T, (2012) Purinergic signaling in human pluripotent cells is regulated by the housekeeping gene hypoxanthine guanine phosphoribosyltransferase. Proc Natl Acad Sci USA 109(9): 3377-3382.
    • (2012) Proc Natl Acad Sci USA , vol.109 , Issue.9 , pp. 3377-3382
    • Mastrangelo, L.1    Kim, J.E.2    Miyanohara, A.3    Kang, T.H.4    Friedmann, T.5
  • 8
    • 84856089519 scopus 로고    scopus 로고
    • MicroRNA-mediated dysregulation of neural developmental genes in HPRT deficiency: Clues for Lesch Nyhan disease?
    • Guibinga GH, Hrustanovic G, Bouic K, Jinnah HA, Friedmann T, (2012) MicroRNA-mediated dysregulation of neural developmental genes in HPRT deficiency: Clues for Lesch Nyhan disease? Hum Mol Genet 21(3): 609-622.
    • (2012) Hum Mol Genet , vol.21 , Issue.3 , pp. 609-622
    • Guibinga, G.H.1    Hrustanovic, G.2    Bouic, K.3    Jinnah, H.A.4    Friedmann, T.5
  • 9
    • 58749105626 scopus 로고    scopus 로고
    • Efficient derivation of functional dopaminergic neurons from human embryonic stem cells on a large scale
    • Cho MS, Hwang DY, Kim DW, (2008) Efficient derivation of functional dopaminergic neurons from human embryonic stem cells on a large scale. Nat Protoc 3(12): 1888-1894.
    • (2008) Nat Protoc , vol.3 , Issue.12 , pp. 1888-1894
    • Cho, M.S.1    Hwang, D.Y.2    Kim, D.W.3
  • 11
    • 0028218268 scopus 로고
    • Dopamine deficiency in a genetic mouse model of Lesch-Nyhan disease
    • Jinnah HA, Wojcik BE, Hunt M, Narang N, Lee KY, Goldstein M, et al. (1994) Dopamine deficiency in a genetic mouse model of Lesch-Nyhan disease. J Neurosci 3(Pt 1): 1164-1175.
    • (1994) J Neurosci , vol.3 , Issue.Pt 1 , pp. 1164-1175
    • Jinnah, H.A.1    Wojcik, B.E.2    Hunt, M.3    Narang, N.4    Lee, K.Y.5    Goldstein, M.6
  • 12
    • 34147100640 scopus 로고    scopus 로고
    • Basal ganglia dopamine loss due to defect in purine recycling
    • Egami K, Yitta S, Kasim S, Lewers JC, Roberts RC, et al. (2007) Basal ganglia dopamine loss due to defect in purine recycling. Neurobiol Dis 26(2): 396-407.
    • (2007) Neurobiol Dis , vol.26 , Issue.2 , pp. 396-407
    • Egami, K.1    Yitta, S.2    Kasim, S.3    Lewers, J.C.4    Roberts, R.C.5
  • 13
    • 13944284590 scopus 로고    scopus 로고
    • Hypothesized deficiency of guanine-based purines may contribute to abnormalities of neurodevelopment, neuromodulation, and neurotransmission in Lesch-Nyhan syndrome
    • Deutsch SI, Long KD, Rosse RB, Mastropaolo J, Eller J, (2005) Hypothesized deficiency of guanine-based purines may contribute to abnormalities of neurodevelopment, neuromodulation, and neurotransmission in Lesch-Nyhan syndrome. Clin Neuropharmacol 28(1): 28-37.
    • (2005) Clin Neuropharmacol , vol.28 , Issue.1 , pp. 28-37
    • Deutsch, S.I.1    Long, K.D.2    Rosse, R.B.3    Mastropaolo, J.4    Eller, J.5
  • 15
    • 73449134439 scopus 로고    scopus 로고
    • Gene set enrichment analysis made simple
    • doi:10.1177/0962280209351908
    • Irizarry RA, Wang C, Zhou Y, Speed TP, (2009) Gene set enrichment analysis made simple. Stat Methods Med Res 18(6): 565-575 doi: 10.1177/0962280209351908.
    • (2009) Stat Methods Med Res , vol.18 , Issue.6 , pp. 565-575
    • Irizarry, R.A.1    Wang, C.2    Zhou, Y.3    Speed, T.P.4
  • 16
    • 0036795867 scopus 로고    scopus 로고
    • Differential expression of protein tyrosine kinase genes during microglial activation
    • Krady JK, Basu A, Levison SW, Milner RJ, (2002) Differential expression of protein tyrosine kinase genes during microglial activation. Glia 40(1): 11-24.
    • (2002) Glia , vol.40 , Issue.1 , pp. 11-24
    • Krady, J.K.1    Basu, A.2    Levison, S.W.3    Milner, R.J.4
  • 17
    • 14044264203 scopus 로고    scopus 로고
    • Inhibition of granulocyte-macrophage colony-stimulating factor signaling and microglial proliferation by anti-CD45RO: role of Hck tyrosine kinase and phosphatidylinositol 3-kinase/Akt J Immunol
    • Suh HS, Kim MO, Lee SC, (2005) Inhibition of granulocyte-macrophage colony-stimulating factor signaling and microglial proliferation by anti-CD45RO: role of Hck tyrosine kinase and phosphatidylinositol 3-kinase/Akt J Immunol. 174(5): 2712-2719.
    • (2005) , vol.174 , Issue.5 , pp. 2712-2719
    • Suh, H.S.1    Kim, M.O.2    Lee, S.C.3
  • 18
    • 0032246118 scopus 로고    scopus 로고
    • Processing of sphingolipid activator proteins and the topology of lysosomal digestion
    • Sandhoff K, Kolter T, (1998) Processing of sphingolipid activator proteins and the topology of lysosomal digestion. Acta Biochim Pol 45(2): 373-384.
    • (1998) Acta Biochim Pol , vol.45 , Issue.2 , pp. 373-384
    • Sandhoff, K.1    Kolter, T.2
  • 19
    • 0033597122 scopus 로고    scopus 로고
    • Inhibition of T cell signaling by mitogen-activated protein kinase-targeted hematopoietic tyrosine phosphatase (HePTP)
    • Saxena M, Williams S, Brockdorff J, Gilman J, Mustelin T, (1999) Inhibition of T cell signaling by mitogen-activated protein kinase-targeted hematopoietic tyrosine phosphatase (HePTP). J Biol Chem 274(17): 11693-11700.
    • (1999) J Biol Chem , vol.274 , Issue.17 , pp. 11693-11700
    • Saxena, M.1    Williams, S.2    Brockdorff, J.3    Gilman, J.4    Mustelin, T.5
  • 20
    • 0033193930 scopus 로고    scopus 로고
    • Crosstalk between cAMP-dependent kinase and MAP kinase through a protein tyrosine phosphatase
    • Saxena M, Williams S, Taskén K, Mustelin T, (1999) Crosstalk between cAMP-dependent kinase and MAP kinase through a protein tyrosine phosphatase. Nat Cell Biol 1(5): 305-311.
    • (1999) Nat Cell Biol , vol.1 , Issue.5 , pp. 305-311
    • Saxena, M.1    Williams, S.2    Taskén, K.3    Mustelin, T.4
  • 22
    • 44849139575 scopus 로고    scopus 로고
    • Correlation of mRNA and protein levels: cell type-specific gene expression of cluster designation antigens in the prostate
    • doi:10.1186/1471-2164-9-246
    • Pascal LE, True LD, Campbell DS, Deutsch EW, Risk M, et al. (2008) Correlation of mRNA and protein levels: cell type-specific gene expression of cluster designation antigens in the prostate. BMC Genomics 2008 May 23 9: 246 doi: 10.1186/1471-2164-9-246.
    • (2008) BMC Genomics 2008 May 23 , vol.9 , pp. 246
    • Pascal, L.E.1    True, L.D.2    Campbell, D.S.3    Deutsch, E.W.4    Risk, M.5
  • 23
    • 76549113395 scopus 로고    scopus 로고
    • Myelination disturbance in a patient with hyperuricemia and hyperserotoninemia combined with 18q deletion syndrome
    • László A, Vörös E, Buga K, Horváth K, Mayer P, et al. (2009) Myelination disturbance in a patient with hyperuricemia and hyperserotoninemia combined with 18q deletion syndrome. Ideggyogy Sz 62(11-12): 413-417.
    • (2009) Ideggyogy Sz , vol.62 , Issue.11-12 , pp. 413-417
    • László, A.1    Vörös, E.2    Buga, K.3    Horváth, K.4    Mayer, P.5
  • 24
    • 79959938167 scopus 로고    scopus 로고
    • Interplay between LXR and Wnt/ß-catenin signaling in the negative regulation of peripheral myelin genes by oxysterols
    • doi:10.1523/JNEUROSCI.0761-11.2011
    • Makoukji J, Shackleford G, Meffre D, Grenier J, Liere P, et al. (2011) Interplay between LXR and Wnt/ß-catenin signaling in the negative regulation of peripheral myelin genes by oxysterols. J Neurosci 31(26): 9620-9629 doi: 10.1523/JNEUROSCI.0761-11.2011.
    • (2011) J Neurosci , vol.31 , Issue.26 , pp. 9620-9629
    • Makoukji, J.1    Shackleford, G.2    Meffre, D.3    Grenier, J.4    Liere, P.5
  • 25
    • 79952406070 scopus 로고    scopus 로고
    • Wnt/beta-catenin signaling is an essential and direct driver of myelin gene expression and myelinogenesis
    • doi:10.1523/JNEUROSCI.4270-10.2011
    • Tawk M, Makoukji J, Belle M, Fonte C, Trousson A, et al. (2011) Wnt/beta-catenin signaling is an essential and direct driver of myelin gene expression and myelinogenesis. J Neurosci 31(10): 3729-3742 doi: 10.1523/JNEUROSCI.4270-10.2011.
    • (2011) J Neurosci , vol.31 , Issue.10 , pp. 3729-3742
    • Tawk, M.1    Makoukji, J.2    Belle, M.3    Fonte, C.4    Trousson, A.5
  • 26
    • 79851503308 scopus 로고    scopus 로고
    • GSK3ß negatively regulates oligodendrocyte differentiation and myelination in vivo
    • doi:10.1002/glia.21122
    • Azim K, Butt AM, (2011) GSK3ß negatively regulates oligodendrocyte differentiation and myelination in vivo. Glia 59(4): 540-553 doi: 10.1002/glia.21122.
    • (2011) Glia , vol.59 , Issue.4 , pp. 540-553
    • Azim, K.1    Butt, A.M.2
  • 27
    • 67649760662 scopus 로고    scopus 로고
    • Genetics meets epigenetics: HDACs and Wnt signaling in myelin development and regeneration
    • Li H, Richardson WD, (2009) Genetics meets epigenetics: HDACs and Wnt signaling in myelin development and regeneration. Nat Neurosci 12(7): 815-817.
    • (2009) Nat Neurosci , vol.12 , Issue.7 , pp. 815-817
    • Li, H.1    Richardson, W.D.2
  • 28
    • 79951988235 scopus 로고    scopus 로고
    • Assessing the role of the cadherin/catenin complex at the Schwann cell-axon interface and in the initiation of myelination
    • doi:10.1523/JNEUROSCI.4345-10.2011
    • Lewallen KA, Shen YA, De la Torre AR, Ng BK, Meijer D, et al. (2011) Assessing the role of the cadherin/catenin complex at the Schwann cell-axon interface and in the initiation of myelination. J Neurosci 31(8): 3032-3043 doi: 10.1523/JNEUROSCI.4345-10.2011.
    • (2011) J Neurosci , vol.31 , Issue.8 , pp. 3032-3043
    • Lewallen, K.A.1    Shen, Y.A.2    De la Torre, A.R.3    Ng, B.K.4    Meijer, D.5
  • 30
    • 79953194397 scopus 로고    scopus 로고
    • HDAC1 and HDAC2 control the transcriptional program of myelination and the survival of Schwann cells
    • doi:10.1038/nn.2762
    • Jacob C, Christen CN, Pereira JA, Somandin C, Baggiolini A, et al. (2011) HDAC1 and HDAC2 control the transcriptional program of myelination and the survival of Schwann cells. Nat Neurosci 14(4): 429-436 doi: 10.1038/nn.2762.
    • (2011) Nat Neurosci , vol.14 , Issue.4 , pp. 429-436
    • Jacob, C.1    Christen, C.N.2    Pereira, J.A.3    Somandin, C.4    Baggiolini, A.5
  • 31
    • 79953186033 scopus 로고    scopus 로고
    • HDAC-mediated deacetylation of NF-κB is critical for Schwann cell myelination
    • doi:10.1038/nn.2780
    • Chen Y, Wang H, Yoon SO, Xu X, Hottiger MO, et al. (2011) HDAC-mediated deacetylation of NF-κB is critical for Schwann cell myelination. Nat Neurosci 14(4): 437-441 doi: 10.1038/nn.2780.
    • (2011) Nat Neurosci , vol.14 , Issue.4 , pp. 437-441
    • Chen, Y.1    Wang, H.2    Yoon, S.O.3    Xu, X.4    Hottiger, M.O.5
  • 32
    • 63849220317 scopus 로고    scopus 로고
    • Olig1 expression identifies developing oligodendrocytes in zebrafish and requires hedgehog and notch signaling
    • Schebesta M, Serluca FC, (2009) Olig1 expression identifies developing oligodendrocytes in zebrafish and requires hedgehog and notch signaling. Dev Dyn 238(4): 887-898.
    • (2009) Dev Dyn , vol.238 , Issue.4 , pp. 887-898
    • Schebesta, M.1    Serluca, F.C.2
  • 33
    • 0036036430 scopus 로고    scopus 로고
    • Olig2 is required for zebrafish primary motor neuron and oligodendrocyte development
    • Park HC, Mehta A, Richardson JS, Appel B, (2002) Olig2 is required for zebrafish primary motor neuron and oligodendrocyte development. Dev Biol 248(2): 356-368.
    • (2002) Dev Biol , vol.248 , Issue.2 , pp. 356-368
    • Park, H.C.1    Mehta, A.2    Richardson, J.S.3    Appel, B.4
  • 34
    • 33749371515 scopus 로고    scopus 로고
    • An oligodendrocyte-specific zinc-finger transcription regulator cooperates with Olig2 to promote oligodendrocyte differentiation
    • Wang SZ, Dulin J, Wu H, Hurlock E, Lee SE, et al. (2006) An oligodendrocyte-specific zinc-finger transcription regulator cooperates with Olig2 to promote oligodendrocyte differentiation. Development 133(17): 3389-3398.
    • (2006) Development , vol.133 , Issue.17 , pp. 3389-3398
    • Wang, S.Z.1    Dulin, J.2    Wu, H.3    Hurlock, E.4    Lee, S.E.5
  • 35
    • 34548204310 scopus 로고    scopus 로고
    • Transcriptional control of oligodendrogenesis
    • Nicolay DJ, Doucette JR, Nazarali AJ, (2007) Transcriptional control of oligodendrogenesis. Glia 55(13): 1287-1299.
    • (2007) Glia , vol.55 , Issue.13 , pp. 1287-1299
    • Nicolay, D.J.1    Doucette, J.R.2    Nazarali, A.J.3
  • 36
    • 0041508452 scopus 로고    scopus 로고
    • Delta-Notch signaling regulates oligodendrocyte specification
    • Park HC, Appel B, (2003) Delta-Notch signaling regulates oligodendrocyte specification. Development 130(16): 3747-3755.
    • (2003) Development , vol.130 , Issue.16 , pp. 3747-3755
    • Park, H.C.1    Appel, B.2
  • 37
    • 84859539293 scopus 로고    scopus 로고
    • Distinct lineage specification roles for NANOG, OCT4, and SOX2 in human embryonic stem cells
    • Wang Z, Oron E, Nelson B, Razis S, Ivanova N, (2012) Distinct lineage specification roles for NANOG, OCT4, and SOX2 in human embryonic stem cells. Cell Stem Cell 10(4): 440-454.
    • (2012) Cell Stem Cell , vol.10 , Issue.4 , pp. 440-454
    • Wang, Z.1    Oron, E.2    Nelson, B.3    Razis, S.4    Ivanova, N.5
  • 38
    • 0041880122 scopus 로고    scopus 로고
    • SOX2 functions to maintain neural progenitor identity
    • Graham V, Khudyakov J, Ellis P, Pevny L, (2003) SOX2 functions to maintain neural progenitor identity. Neuron 39(5): 749-765.
    • (2003) Neuron , vol.39 , Issue.5 , pp. 749-765
    • Graham, V.1    Khudyakov, J.2    Ellis, P.3    Pevny, L.4
  • 39
    • 0242353154 scopus 로고    scopus 로고
    • Vertebrate neurogenesis is counteracted by Sox1-3 activity
    • Bylund M, Andersson E, Novitch BG, Muhr J, (2003) Vertebrate neurogenesis is counteracted by Sox1-3 activity. Nat Neurosci 6(11): 1162-1168.
    • (2003) Nat Neurosci , vol.6 , Issue.11 , pp. 1162-1168
    • Bylund, M.1    Andersson, E.2    Novitch, B.G.3    Muhr, J.4
  • 40
    • 13844302847 scopus 로고    scopus 로고
    • SOX2, a persistent marker for multipotential neural stem cells derived from embryonic stem cells, the embryo or the adult
    • Ellis P, Fagan BM, Magness ST, Hutton S, Taranova O, et al. (2004) SOX2, a persistent marker for multipotential neural stem cells derived from embryonic stem cells, the embryo or the adult. Dev Neurosci 26(2-4): 148-165.
    • (2004) Dev Neurosci , vol.26 , Issue.2-4 , pp. 148-165
    • Ellis, P.1    Fagan, B.M.2    Magness, S.T.3    Hutton, S.4    Taranova, O.5
  • 41
    • 38949123730 scopus 로고    scopus 로고
    • A mechanism regulating the onset of Sox2 expression in the embryonic neural plate
    • Papanayotou C, Mey A, Birot AM, Saka Y, Boast S, et al. (2008) A mechanism regulating the onset of Sox2 expression in the embryonic neural plate. PLoS Biol 6(1): e2.
    • (2008) PLoS Biol , vol.6 , Issue.1
    • Papanayotou, C.1    Mey, A.2    Birot, A.M.3    Saka, Y.4    Boast, S.5
  • 43
    • 84874617047 scopus 로고    scopus 로고
    • Progression of neurogenesis in the inner ear requires inhibition of sox2 transcription by neurogenin1 and neurod1
    • doi:10.1523/JNEUROSCI.4030-12.2013
    • Evsen L, Sugahara S, Uchikawa M, Kondoh H, Wu DK, (2013) Progression of neurogenesis in the inner ear requires inhibition of sox2 transcription by neurogenin1 and neurod1. J Neurosci 33(9): 3879-3890 doi: 10.1523/JNEUROSCI.4030-12.2013.
    • (2013) J Neurosci , vol.33 , Issue.9 , pp. 3879-3890
    • Evsen, L.1    Sugahara, S.2    Uchikawa, M.3    Kondoh, H.4    Wu, D.K.5
  • 44
    • 13944284590 scopus 로고    scopus 로고
    • Hypothesized deficiency of guanine-based purines may contribute to abnormalities of neurodevelopment, neuromodulation, and neurotransmission in Lesch-Nyhan syndrome
    • Deutsch SI, Long KD, Rosse RB, Mastropaolo J, Eller J, (2005) Hypothesized deficiency of guanine-based purines may contribute to abnormalities of neurodevelopment, neuromodulation, and neurotransmission in Lesch-Nyhan syndrome. Clin Neuropharmacol 28(1): 28-37.
    • (2005) Clin Neuropharmacol , vol.28 , Issue.1 , pp. 28-37
    • Deutsch, S.I.1    Long, K.D.2    Rosse, R.B.3    Mastropaolo, J.4    Eller, J.5
  • 45
    • 33644878797 scopus 로고    scopus 로고
    • Decreased GTP-stimulated adenylyl cyclase activity in HPRT-deficient human and mouse fibroblast and rat B103 neuroblastoma cell membranes
    • Pinto CS, Seifert R, (2006) Decreased GTP-stimulated adenylyl cyclase activity in HPRT-deficient human and mouse fibroblast and rat B103 neuroblastoma cell membranes. J Neurochem 96(2): 454-459.
    • (2006) J Neurochem , vol.96 , Issue.2 , pp. 454-459
    • Pinto, C.S.1    Seifert, R.2
  • 46
    • 20744439988 scopus 로고    scopus 로고
    • Altered membrane NTPase activity in Lesch-Nyhan disease fibroblasts: comparison with HPRT knockout mice and HPRT-deficient cell lines
    • Pinto CS, Jinnah HA, Shirley TL, Nyhan WL, Seifert R, (2005) Altered membrane NTPase activity in Lesch-Nyhan disease fibroblasts: comparison with HPRT knockout mice and HPRT-deficient cell lines. J Neurochem 93(6): 1579-1586.
    • (2005) J Neurochem , vol.93 , Issue.6 , pp. 1579-1586
    • Pinto, C.S.1    Jinnah, H.A.2    Shirley, T.L.3    Nyhan, W.L.4    Seifert, R.5
  • 47
    • 84867884694 scopus 로고    scopus 로고
    • Adenosine, dopamine and serotonin receptors imbalance in lymphocytes of Lesch-Nyhan patients
    • Garcia M, Puig J, Torres R, (2012) Adenosine, dopamine and serotonin receptors imbalance in lymphocytes of Lesch-Nyhan patients. Journal of Inherited Metabolic Disease 35(6): 1129-1135.
    • (2012) Journal of Inherited Metabolic Disease , vol.35 , Issue.6 , pp. 1129-1135
    • Garcia, M.1    Puig, J.2    Torres, R.3
  • 48
    • 67649945834 scopus 로고    scopus 로고
    • Gene expression and mRNA editing of serotonin receptor 2C in brains of HPRT gene knock-out mice, an animal model of Lesch-Nyhan disease
    • doi:10.1016/j.jocn.2008.12.011
    • Bertelli M, Alushi B, Veicsteinas A, Jinnah HA, Micheli V, (2009) Gene expression and mRNA editing of serotonin receptor 2C in brains of HPRT gene knock-out mice, an animal model of Lesch-Nyhan disease. J Clin Neurosci 16(8): 1061-1063 doi: 10.1016/j.jocn.2008.12.011.
    • (2009) J Clin Neurosci , vol.16 , Issue.8 , pp. 1061-1063
    • Bertelli, M.1    Alushi, B.2    Veicsteinas, A.3    Jinnah, H.A.4    Micheli, V.5
  • 49
    • 33747882180 scopus 로고    scopus 로고
    • Study of the adenosinergic system in the brain of HPRT knockout mouse (Lesch-Nyhan disease)
    • Bertelli M, Cecchin S, Lapucci C, Jacomelli G, Jinnah HA, et al. (2006) Study of the adenosinergic system in the brain of HPRT knockout mouse (Lesch-Nyhan disease). Clin Chim Acta 373(1-2): 104-107.
    • (2006) Clin Chim Acta , vol.373 , Issue.1-2 , pp. 104-107
    • Bertelli, M.1    Cecchin, S.2    Lapucci, C.3    Jacomelli, G.4    Jinnah, H.A.5
  • 50
    • 0033839296 scopus 로고    scopus 로고
    • Neurotransmitter changes in the pathophysiology of Lesch-Nyhan syndrome
    • Saito Y, Takashima S, (2000) Neurotransmitter changes in the pathophysiology of Lesch-Nyhan syndrome. Brain Dev 22(Suppl. 1): S122-S131.
    • (2000) Brain Dev , vol.22
    • Saito, Y.1    Takashima, S.2
  • 51
    • 82655189157 scopus 로고    scopus 로고
    • Cannabidiol reduces Aß-induced neuroinflammation and promotes hippocampal neurogenesis through PPARγ involvement
    • doi:10.1371/journal.pone.0028668
    • Esposito G, Scuderi C, Valenza M, Togna GI, Latina V, et al. (2011) Cannabidiol reduces Aß-induced neuroinflammation and promotes hippocampal neurogenesis through PPARγ involvement. PLoS One 6(12): e28668 doi: 10.1371/journal.pone.0028668.
    • (2011) PLoS One , vol.6 , Issue.12
    • Esposito, G.1    Scuderi, C.2    Valenza, M.3    Togna, G.I.4    Latina, V.5
  • 52
    • 84860123393 scopus 로고    scopus 로고
    • Full and partial peroxisome proliferation-activated receptor-γ agonists, but not δ agonist, rescue of dopaminergic neurons in the 6-OHDA parkinsonian model is associated with inhibition of microglial activation and MMP expression
    • Sadeghian M, Marinova-Mutafchieva L, Broom L, Davis JB, Virley D, et al. (2012) Full and partial peroxisome proliferation-activated receptor-γ agonists, but not δ agonist, rescue of dopaminergic neurons in the 6-OHDA parkinsonian model is associated with inhibition of microglial activation and MMP expression. J Neuroimmunol 246(1-2): 69-77.
    • (2012) J Neuroimmunol , vol.246 , Issue.1-2 , pp. 69-77
    • Sadeghian, M.1    Marinova-Mutafchieva, L.2    Broom, L.3    Davis, J.B.4    Virley, D.5
  • 53
    • 0036081355 scopus 로고    scopus 로고
    • Gene Expression Omnibus: NCBI gene expression and hybridization array data repository
    • Edgar R, Domrachev M, Lash AE, (2002) Gene Expression Omnibus: NCBI gene expression and hybridization array data repository. Nucleic Acids Res 30(1): 207-210.
    • (2002) Nucleic Acids Res , vol.30 , Issue.1 , pp. 207-210
    • Edgar, R.1    Domrachev, M.2    Lash, A.E.3
  • 54
    • 65449136284 scopus 로고    scopus 로고
    • TopHat: discovering splice junctions with RNA-Seq
    • doi:10.1093/bioinformatics/btp120
    • Trapnell C, Pachter L, Salzberg SL, (2009) TopHat: discovering splice junctions with RNA-Seq. Bioinformatics 25(9): 1105-1111 doi: 10.1093/bioinformatics/btp120.
    • (2009) Bioinformatics , vol.25 , Issue.9 , pp. 1105-1111
    • Trapnell, C.1    Pachter, L.2    Salzberg, S.L.3
  • 55
    • 77952123055 scopus 로고    scopus 로고
    • Transcript assembly and quantification by RNA-Seq reveals unannotated transcripts and isoform switching during cell differentiation
    • doi:10.1038/nbt.1621
    • Trapnell C, Williams BA, Pertea G, Mortazavi A, Kwan G, et al. (2010) Transcript assembly and quantification by RNA-Seq reveals unannotated transcripts and isoform switching during cell differentiation. Nat Biotechnol 28(5): 511-515 doi: 10.1038/nbt.1621.
    • (2010) Nat Biotechnol , vol.28 , Issue.5 , pp. 511-515
    • Trapnell, C.1    Williams, B.A.2    Pertea, G.3    Mortazavi, A.4    Kwan, G.5
  • 56
    • 84872198346 scopus 로고    scopus 로고
    • Differential analysis of gene regulation at transcript resolution with RNA-seq
    • doi:10.1038/nbt.2450
    • Trapnell C, Hendrickson DG, Sauvageau M, Goff L, Rinn JL, et al. (2013) Differential analysis of gene regulation at transcript resolution with RNA-seq. Nat Biotechnol 31(1): 46-53 doi: 10.1038/nbt.2450.
    • (2013) Nat Biotechnol , vol.31 , Issue.1 , pp. 46-53
    • Trapnell, C.1    Hendrickson, D.G.2    Sauvageau, M.3    Goff, L.4    Rinn, J.L.5


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