메뉴 건너뛰기




Volumn 63, Issue , 2016, Pages 86-93

Disrupted glucocorticoid-Immune interactions during stress response in schizophrenia

Author keywords

Cortisol; IL 6; Inflammation; Schizophrenia; Stress

Indexed keywords

HYDROCORTISONE; INTERLEUKIN 6; GLUCOCORTICOID; IL6 PROTEIN, HUMAN; NEUROLEPTIC AGENT;

EID: 84949844546     PISSN: 03064530     EISSN: 18733360     Source Type: Journal    
DOI: 10.1016/j.psyneuen.2015.09.010     Document Type: Article
Times cited : (24)

References (67)
  • 3
    • 84857094629 scopus 로고    scopus 로고
    • Autoimmune diseases and severe infections as risk factors for schizophrenia: a 30-year population-based register study
    • Benros M.E., Nielsen P.R., Nordentoft M., Eaton W.W., Dalton S.O., Mortensen P.B. Autoimmune diseases and severe infections as risk factors for schizophrenia: a 30-year population-based register study. Am. J. Psychiatry 2011, 168:1303-1310.
    • (2011) Am. J. Psychiatry , vol.168 , pp. 1303-1310
    • Benros, M.E.1    Nielsen, P.R.2    Nordentoft, M.3    Eaton, W.W.4    Dalton, S.O.5    Mortensen, P.B.6
  • 4
    • 84892585004 scopus 로고    scopus 로고
    • Autoimmunity, inflammation, and psychosis: a search for peripheral markers
    • Bergink V., Gibney S.M., Drexhage H.A. Autoimmunity, inflammation, and psychosis: a search for peripheral markers. Biol. Psychiatry 2014, 75:324-331.
    • (2014) Biol. Psychiatry , vol.75 , pp. 324-331
    • Bergink, V.1    Gibney, S.M.2    Drexhage, H.A.3
  • 7
    • 77958062011 scopus 로고    scopus 로고
    • Stress and sex versus immunity and inflammation
    • Chrousos G.P. Stress and sex versus immunity and inflammation. Sci. Signal. 2010, 3:pe36.
    • (2010) Sci. Signal. , vol.3 , pp. pe36
    • Chrousos, G.P.1
  • 8
    • 79951578573 scopus 로고    scopus 로고
    • The anti-inflammatory and immunosuppressive effects of glucocorticoids, recent developments and mechanistic insights
    • Coutinho A.E., Chapman K.E. The anti-inflammatory and immunosuppressive effects of glucocorticoids, recent developments and mechanistic insights. Mol. Cell. Endocrinol. 2011, 335:2-13.
    • (2011) Mol. Cell. Endocrinol. , vol.335 , pp. 2-13
    • Coutinho, A.E.1    Chapman, K.E.2
  • 9
    • 0032774277 scopus 로고    scopus 로고
    • Sex hormones and glucocorticoids: interactions with the immune system
    • Da Silva J.A. Sex hormones and glucocorticoids: interactions with the immune system. Ann. N. Y. Acad. Sci. 1999, 876:102-117.
    • (1999) Ann. N. Y. Acad. Sci. , vol.876 , pp. 102-117
    • Da Silva, J.A.1
  • 10
    • 20444463577 scopus 로고    scopus 로고
    • A meta-analysis of worldwide studies demonstrates an association between schizophrenia and tobacco smoking behaviors
    • de Leon J., Diaz F.J. A meta-analysis of worldwide studies demonstrates an association between schizophrenia and tobacco smoking behaviors. Schizophr. Res. 2005, 76:135-157.
    • (2005) Schizophr. Res. , vol.76 , pp. 135-157
    • de Leon, J.1    Diaz, F.J.2
  • 11
    • 53249084473 scopus 로고    scopus 로고
    • General and specific cognitive deficits in schizophrenia: Goliath defeats David?
    • Dickinson D., Ragland J.D., Gold J.M., Gur R.C. General and specific cognitive deficits in schizophrenia: Goliath defeats David?. Biol. Psychiatry 2008, 64:823-827.
    • (2008) Biol. Psychiatry , vol.64 , pp. 823-827
    • Dickinson, D.1    Ragland, J.D.2    Gold, J.M.3    Gur, R.C.4
  • 12
    • 65349111411 scopus 로고    scopus 로고
    • Life events and high-trait reactivity together predict psychotic symptom increases in schizophrenia
    • Docherty N.M., St Hilaire A., Aakre J.M., Seghers J.P. Life events and high-trait reactivity together predict psychotic symptom increases in schizophrenia. Schizophr. Bull. 2009, 35:638-645.
    • (2009) Schizophr. Bull. , vol.35 , pp. 638-645
    • Docherty, N.M.1    St Hilaire, A.2    Aakre, J.M.3    Seghers, J.P.4
  • 13
    • 34250368460 scopus 로고    scopus 로고
    • Salivary cortisol reflects serum cortisol: analysis of circadian profiles
    • Dorn L.D., Lucke J.F., Loucks T.L., Berga S.L. Salivary cortisol reflects serum cortisol: analysis of circadian profiles. Ann. Clin. Biochem. 2007, 44:281-284.
    • (2007) Ann. Clin. Biochem. , vol.44 , pp. 281-284
    • Dorn, L.D.1    Lucke, J.F.2    Loucks, T.L.3    Berga, S.L.4
  • 14
    • 79952116875 scopus 로고    scopus 로고
    • Sexually dimorphic actions of glucocorticoids provide a link to inflammatory diseases with gender differences in prevalence
    • Duma D., Collins J.B., Chou J.W., Cidlowski J.A. Sexually dimorphic actions of glucocorticoids provide a link to inflammatory diseases with gender differences in prevalence. Sci. Signal. 2010, 3:ra74.
    • (2010) Sci. Signal. , vol.3 , pp. ra74
    • Duma, D.1    Collins, J.B.2    Chou, J.W.3    Cidlowski, J.A.4
  • 16
    • 84876945142 scopus 로고    scopus 로고
    • Inflammatory cytokines and neurological and neurocognitive alterations in the course of schizophrenia
    • Fineberg A.M., Ellman L.M. Inflammatory cytokines and neurological and neurocognitive alterations in the course of schizophrenia. Biol. Psychiatry 2013, 73:951-966.
    • (2013) Biol. Psychiatry , vol.73 , pp. 951-966
    • Fineberg, A.M.1    Ellman, L.M.2
  • 18
    • 84939534588 scopus 로고    scopus 로고
    • Interleukin-6: the missing element of the neurocognitive deterioration in schizophrenia? The focus on genetic underpinnings, cognitive impairment and clinical manifestation
    • Frydecka D., Misiak B., Pawlak-Adamska E., Karabon L., Tomkiewicz A., Sedlaczek P., Kiejna A., Beszłej J.A. Interleukin-6: the missing element of the neurocognitive deterioration in schizophrenia? The focus on genetic underpinnings, cognitive impairment and clinical manifestation. Eur. Arch. Psychiatry Clin. Neurosci. 2015, 265:449-459.
    • (2015) Eur. Arch. Psychiatry Clin. Neurosci. , vol.265 , pp. 449-459
    • Frydecka, D.1    Misiak, B.2    Pawlak-Adamska, E.3    Karabon, L.4    Tomkiewicz, A.5    Sedlaczek, P.6    Kiejna, A.7    Beszłej, J.A.8
  • 22
    • 0037302873 scopus 로고    scopus 로고
    • Cytokines: regulation of the hypothalamo-pituitary-adrenocortical axis
    • John C.D., Buckingham J.C. Cytokines: regulation of the hypothalamo-pituitary-adrenocortical axis. Curr. Opin. Pharmacol. 2003, 3:78-84.
    • (2003) Curr. Opin. Pharmacol. , vol.3 , pp. 78-84
    • John, C.D.1    Buckingham, J.C.2
  • 25
    • 84957553801 scopus 로고    scopus 로고
    • The role of cortisol in first episode of psychosis: a systematic review
    • Karanikas E., Antoniadis D., Garyfallos G.D. The role of cortisol in first episode of psychosis: a systematic review. Curr. Psychiatry Rep. 2014, 16:503.
    • (2014) Curr. Psychiatry Rep. , vol.16 , pp. 503
    • Karanikas, E.1    Antoniadis, D.2    Garyfallos, G.D.3
  • 26
    • 1942536959 scopus 로고    scopus 로고
    • The brief assessment of cognition in schizophrenia: reliability, sensitivity, and comparison with a standard neurocognitive battery
    • Keefe R.S., Goldberg T.E., Harvey P.D., Gold J.M., Poe M.P., Coughenour L. The brief assessment of cognition in schizophrenia: reliability, sensitivity, and comparison with a standard neurocognitive battery. Schizophr. Res. 2004, 68:283-297.
    • (2004) Schizophr. Res. , vol.68 , pp. 283-297
    • Keefe, R.S.1    Goldberg, T.E.2    Harvey, P.D.3    Gold, J.M.4    Poe, M.P.5    Coughenour, L.6
  • 28
    • 0026485304 scopus 로고
    • Interleukin-6 and its receptor: a paradigm for cytokines
    • Kishimoto T., Akira S., Taga T. Interleukin-6 and its receptor: a paradigm for cytokines. Science 1992, 258:593-597.
    • (1992) Science , vol.258 , pp. 593-597
    • Kishimoto, T.1    Akira, S.2    Taga, T.3
  • 30
    • 0034894803 scopus 로고    scopus 로고
    • Plasma cytokine response to surgical stress in schizophrenic patients
    • Kudoh A., Sakai T., Ishihara H., Matsuki A. Plasma cytokine response to surgical stress in schizophrenic patients. Clin. Exp. Immunol. 2001, 125:89-93.
    • (2001) Clin. Exp. Immunol. , vol.125 , pp. 89-93
    • Kudoh, A.1    Sakai, T.2    Ishihara, H.3    Matsuki, A.4
  • 31
    • 0043236220 scopus 로고    scopus 로고
    • Cortisol responses to mild psychological stress are inversely associated with proinflammatory cytokines
    • Kunz-Ebrecht S.R., Mohamed-Ali V., Feldman P.J., Kirschbaum C., Steptoe A. Cortisol responses to mild psychological stress are inversely associated with proinflammatory cytokines. Brain Behav. Immun. 2003, 17:373-383.
    • (2003) Brain Behav. Immun. , vol.17 , pp. 373-383
    • Kunz-Ebrecht, S.R.1    Mohamed-Ali, V.2    Feldman, P.J.3    Kirschbaum, C.4    Steptoe, A.5
  • 32
    • 0025372712 scopus 로고
    • The effects of psychological stress on plasma interleukin-6 activity in rats
    • LeMay L.G., Vander A.J., Kluger M.J. The effects of psychological stress on plasma interleukin-6 activity in rats. Physiol. Behav. 1990, 47:957-961.
    • (1990) Physiol. Behav. , vol.47 , pp. 957-961
    • LeMay, L.G.1    Vander, A.J.2    Kluger, M.J.3
  • 33
    • 1542342707 scopus 로고    scopus 로고
    • A modified computer version of the paced auditory serial addition task (PASAT) as a laboratory based stressor
    • Lejuez C., Kahler C.W., Brown R.A. A modified computer version of the paced auditory serial addition task (PASAT) as a laboratory based stressor. Behav. Ther. 2003, 26:290-293.
    • (2003) Behav. Ther. , vol.26 , pp. 290-293
    • Lejuez, C.1    Kahler, C.W.2    Brown, R.A.3
  • 34
    • 0025743630 scopus 로고
    • The effect of interleukin-6 on pituitary hormone release in vivo and in vitro
    • Lyson K., McCann S.M. The effect of interleukin-6 on pituitary hormone release in vivo and in vitro. Neuroendocrinology 1991, 54:262-266.
    • (1991) Neuroendocrinology , vol.54 , pp. 262-266
    • Lyson, K.1    McCann, S.M.2
  • 35
    • 0029079357 scopus 로고
    • Interleukin-2 and interleukin-6 in schizophrenia and mania: effects of neuroleptics and mood stabilizers
    • Maes M., Bosmans E., Calabrese J., Smith R., Meltzer H.Y. Interleukin-2 and interleukin-6 in schizophrenia and mania: effects of neuroleptics and mood stabilizers. J Psychiatr. Res 1995, 29:141-152.
    • (1995) J Psychiatr. Res , vol.29 , pp. 141-152
    • Maes, M.1    Bosmans, E.2    Calabrese, J.3    Smith, R.4    Meltzer, H.Y.5
  • 36
    • 0027131202 scopus 로고
    • Recombinant interleukin-6 activates the hypothalamic-pituitary-adrenal axis in humans
    • Mastorakos G., Chrousos G.P., Weber J.S. Recombinant interleukin-6 activates the hypothalamic-pituitary-adrenal axis in humans. J. Clin. Endocrinol. Metab. 1993, 77:1690-1694.
    • (1993) J. Clin. Endocrinol. Metab. , vol.77 , pp. 1690-1694
    • Mastorakos, G.1    Chrousos, G.P.2    Weber, J.S.3
  • 37
    • 80052853015 scopus 로고    scopus 로고
    • Meta-analysis of cytokine alterations in schizophrenia: clinical status and antipsychotic effects
    • Miller B.J., Buckley P., Seabolt W., Mellor A., Kirkpatrick B. Meta-analysis of cytokine alterations in schizophrenia: clinical status and antipsychotic effects. Biol. Psychiatry 2011, 70:663-671.
    • (2011) Biol. Psychiatry , vol.70 , pp. 663-671
    • Miller, B.J.1    Buckley, P.2    Seabolt, W.3    Mellor, A.4    Kirkpatrick, B.5
  • 39
    • 33947203726 scopus 로고    scopus 로고
    • Stress-reactivity in psychosis: evidence for an affective pathway to psychosis
    • Myin-Germeys I., van Os J. Stress-reactivity in psychosis: evidence for an affective pathway to psychosis. Clin. Psychol. Rev. 2007, 27:409-424.
    • (2007) Clin. Psychol. Rev. , vol.27 , pp. 409-424
    • Myin-Germeys, I.1    van Os, J.2
  • 41
    • 84923077204 scopus 로고    scopus 로고
    • Psychiatric genome-wide association study analyses implicate neuronal, immune and histone pathways
    • Network and Pathway Analysis Subgroup of the Psychiatric Genomics Consortium, International Inflammatory Bowel Disease Genetics Consortium (IIBDGC), International Inflammatory Bowel Disease Genetics Consortium IIBDGC Psychiatric genome-wide association study analyses implicate neuronal, immune and histone pathways. Nat. Neurosci. 2015, 18:199-209.
    • (2015) Nat. Neurosci. , vol.18 , pp. 199-209
  • 44
    • 0000503515 scopus 로고
    • The brief psychiatric rating scale
    • Overall J.E., Gorham D.R. The brief psychiatric rating scale. Psychol. Rep. 1962, 10:799-812.
    • (1962) Psychol. Rep. , vol.10 , pp. 799-812
    • Overall, J.E.1    Gorham, D.R.2
  • 45
    • 40949107708 scopus 로고    scopus 로고
    • Inflammatory cytokine alterations in schizophrenia: a systematic quantitative review
    • Potvin S., Stip E., Sepehry A.A., Gendron A., Bah R., Kouassi E. Inflammatory cytokine alterations in schizophrenia: a systematic quantitative review. Biol. Psychiatry 2008, 63:801-808.
    • (2008) Biol. Psychiatry , vol.63 , pp. 801-808
    • Potvin, S.1    Stip, E.2    Sepehry, A.A.3    Gendron, A.4    Bah, R.5    Kouassi, E.6
  • 46
    • 0028107237 scopus 로고
    • Physical association and functional antagonism between the ~65 subunit of transcription factor NF-kappa B and the glucocorticoid receptor
    • Ray A., Prefontaine K.E. Physical association and functional antagonism between the ~65 subunit of transcription factor NF-kappa B and the glucocorticoid receptor. Proc. Natl. Acad. Sci. U. S. A. 1994, 91:752-756.
    • (1994) Proc. Natl. Acad. Sci. U. S. A. , vol.91 , pp. 752-756
    • Ray, A.1    Prefontaine, K.E.2
  • 47
    • 26844433194 scopus 로고    scopus 로고
    • Anti-inflammatory action of glucocorticoids-new mechanisms for old drugs
    • Rhen T., Cidlowski J.A. Anti-inflammatory action of glucocorticoids-new mechanisms for old drugs. N. Engl. J. Med. 2005, 353:1711-1723.
    • (2005) N. Engl. J. Med. , vol.353 , pp. 1711-1723
    • Rhen, T.1    Cidlowski, J.A.2
  • 48
    • 84856582487 scopus 로고    scopus 로고
    • Acute and chronic stress induced changes in sensitivity of peripheral inflammatory pathways to the signals of multiple stress systems-2011Curt Richter Award Winner
    • Rohleder N. Acute and chronic stress induced changes in sensitivity of peripheral inflammatory pathways to the signals of multiple stress systems-2011Curt Richter Award Winner. Psychoneuroendocrinology 2012, 37:307-316.
    • (2012) Psychoneuroendocrinology , vol.37 , pp. 307-316
    • Rohleder, N.1
  • 49
    • 1842818812 scopus 로고    scopus 로고
    • Evidence of basal pituitary-adrenal overactivity in first episode, drug naive patients with schizophrenia
    • Ryan M., Sharifi N., Condren R., Thakore J.H. Evidence of basal pituitary-adrenal overactivity in first episode, drug naive patients with schizophrenia. Psychoneuroendocrinology 2004, 29:1065-1070.
    • (2004) Psychoneuroendocrinology , vol.29 , pp. 1065-1070
    • Ryan, M.1    Sharifi, N.2    Condren, R.3    Thakore, J.H.4
  • 50
    • 84904804929 scopus 로고    scopus 로고
    • Biological insights from 108 schizophrenia-associated genetic loci
    • Schizophrenia Working Group of the Psychiatric Genomics Consortium Biological insights from 108 schizophrenia-associated genetic loci. Nature 2014, 511:421-427.
    • (2014) Nature , vol.511 , pp. 421-427
  • 51
    • 0026474748 scopus 로고
    • Regulation of IL6 gene expression. In: 46th Forum in Immunology
    • Sehgal P.B. Regulation of IL6 gene expression. In: 46th Forum in Immunology. Res. Immunol. 1992, 143:724-734.
    • (1992) Res. Immunol. , vol.143 , pp. 724-734
    • Sehgal, P.B.1
  • 52
    • 84864083173 scopus 로고    scopus 로고
    • Glucocorticoid regulation of inflammation and its functional correlates: from HPA axis to glucocorticoid receptor dysfunction
    • Silverman M.N., Sternberg E.M. Glucocorticoid regulation of inflammation and its functional correlates: from HPA axis to glucocorticoid receptor dysfunction. Ann. N. Y. Acad. Sci. 2012, 1261:55-63.
    • (2012) Ann. N. Y. Acad. Sci. , vol.1261 , pp. 55-63
    • Silverman, M.N.1    Sternberg, E.M.2
  • 53
    • 33645988488 scopus 로고    scopus 로고
    • Interleukin-6 levels in relation to psychosocial factors: studies on serum, saliva, and in vitro production by blood mononuclear cells
    • Sjögren E., Leanderson P., Kristenson M., Ernerudh J. Interleukin-6 levels in relation to psychosocial factors: studies on serum, saliva, and in vitro production by blood mononuclear cells. Brain Behav. Immun. 2006, 20:270-278.
    • (2006) Brain Behav. Immun. , vol.20 , pp. 270-278
    • Sjögren, E.1    Leanderson, P.2    Kristenson, M.3    Ernerudh, J.4
  • 56
    • 34548049265 scopus 로고    scopus 로고
    • The effects of acute psychological stress on circulating inflammatory factors in humans: a review and meta-analysis
    • Steptoe A., Hamer M., Chida Y. The effects of acute psychological stress on circulating inflammatory factors in humans: a review and meta-analysis. Brain Behav. Immun. 2007, 21:901-912.
    • (2007) Brain Behav. Immun. , vol.21 , pp. 901-912
    • Steptoe, A.1    Hamer, M.2    Chida, Y.3
  • 57
    • 84893393902 scopus 로고    scopus 로고
    • Increased serum interleukin-6 levels in early stages of psychosis: associations with at-risk mental states and the severity of psychotic symptoms
    • Stojanovic A., Martorell L., Montalvo I., Ortega L., Monseny R., Vilella E., Labad J. Increased serum interleukin-6 levels in early stages of psychosis: associations with at-risk mental states and the severity of psychotic symptoms. Psychoneuroendocrinology 2014, 41:23-32.
    • (2014) Psychoneuroendocrinology , vol.41 , pp. 23-32
    • Stojanovic, A.1    Martorell, L.2    Montalvo, I.3    Ortega, L.4    Monseny, R.5    Vilella, E.6    Labad, J.7
  • 59
    • 79952145883 scopus 로고    scopus 로고
    • Longitudinal study of stressful life events and daily stressors among adolescents at high risk for psychotic disorders
    • Tessner K.D., Mittal V., Walker E.F. Longitudinal study of stressful life events and daily stressors among adolescents at high risk for psychotic disorders. Schizophr. Bull. 2011, 37:432-441.
    • (2011) Schizophr. Bull. , vol.37 , pp. 432-441
    • Tessner, K.D.1    Mittal, V.2    Walker, E.F.3
  • 60
    • 84899493726 scopus 로고    scopus 로고
    • Cytokine function in medication-naive first episode psychosis: a systematic review and meta-analysis
    • Upthegrove R., Manzanares-Teson N., Barnes N.M. Cytokine function in medication-naive first episode psychosis: a systematic review and meta-analysis. Schizophr. Res. 2014, 155:101-108.
    • (2014) Schizophr. Res. , vol.155 , pp. 101-108
    • Upthegrove, R.1    Manzanares-Teson, N.2    Barnes, N.M.3
  • 61
    • 0031897892 scopus 로고    scopus 로고
    • Prenatal exposure to maternal stress and subsequent schizophrenia. The May 1940 invasion of the Netherlands
    • van Os J., Selten J. Prenatal exposure to maternal stress and subsequent schizophrenia. The May 1940 invasion of the Netherlands. Br. J. Psychiatry 1998, 172:324-326.
    • (1998) Br. J. Psychiatry , vol.172 , pp. 324-326
    • van Os, J.1    Selten, J.2
  • 63
    • 54249120358 scopus 로고    scopus 로고
    • Psychosocial stress and psychosis. A review of the neurobiological mechanisms and the evidence for gene-stress interaction
    • van Winkel R., Stefanis N.C., Myin-Germeys I. Psychosocial stress and psychosis. A review of the neurobiological mechanisms and the evidence for gene-stress interaction. Schizophr. Bull. 2008, 34:1095-1105.
    • (2008) Schizophr. Bull. , vol.34 , pp. 1095-1105
    • van Winkel, R.1    Stefanis, N.C.2    Myin-Germeys, I.3
  • 64
    • 84861647648 scopus 로고    scopus 로고
    • Childhood adversities increase the risk of psychosis: a meta-analysis of patient-control, prospective- and cross-sectional cohort studies
    • Varese F., Smeets F., Drukker M., Lieverse R., Lataster T., Viechtbauer W., Read J., van O., S.J., Bentall R.P. Childhood adversities increase the risk of psychosis: a meta-analysis of patient-control, prospective- and cross-sectional cohort studies. Schizophr. Bull. 2012, 38:661-671.
    • (2012) Schizophr. Bull. , vol.38 , pp. 661-671
    • Varese, F.1    Smeets, F.2    Drukker, M.3    Lieverse, R.4    Lataster, T.5    Viechtbauer, W.6    Read, J.7    van, O.8    Bentall, R.P.9
  • 67
    • 0027131192 scopus 로고
    • Exposure to physical and psychological stressors elevates plasma interleukin 6: relationship to the activation of hypothalamic-pituitary-adrenal axis
    • Zhou D., Kusnecov A.W., Shurin M.R., DePaoli M., Rabin B.S. Exposure to physical and psychological stressors elevates plasma interleukin 6: relationship to the activation of hypothalamic-pituitary-adrenal axis. Endocrinology 1993, 133:2523-2530.
    • (1993) Endocrinology , vol.133 , pp. 2523-2530
    • Zhou, D.1    Kusnecov, A.W.2    Shurin, M.R.3    DePaoli, M.4    Rabin, B.S.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.