Cefsulodin Inspired Potent and Selective Inhibitors of mPTPB, a Virulent Phosphatase from Mycobacterium tuberculosis

ACS Medicinal Chemistry Letters

Volumn 6, Issue 12, 2015, Pages 1231-1235

  He, Rongjun ^a   Yu, Zhi Hong ^a   Zhang, Ruo Yu ^a   Wu, Li ^a   Gunawan, Andrea M ^a   Zhang, Zhong Yin ^a  

^a INDIANA UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

antituberculosis; mPTPB inhibitor; Protein tyrosine phosphatase; pTyr mimetics

Indexed keywords

ACETIC ACID DERIVATIVE; ALPHA SULFOPHENYLACETIC AMIDE; CEFSULODIN; PROTEIN TYROSINE PHOSPHATASE; SULFONE DERIVATIVE; UNCLASSIFIED DRUG;

ANTIBACTERIAL ACTIVITY; ARTICLE; DRUG POTENCY; DRUG SELECTIVITY; DRUG TARGETING; LIGAND BINDING; MACROPHAGE; MOLECULAR DOCKING; MOLECULAR WEIGHT; MYCOBACTERIUM TUBERCULOSIS; NONHUMAN; PHARMACOPHORE; PRIORITY JOURNAL; STRUCTURE ACTIVITY RELATION;

EID: 84949766668     PISSN: None     EISSN: 19485875     Source Type: Journal    
DOI: 10.1021/acsmedchemlett.5b00373     Document Type: Article

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