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Volumn 4, Issue 12, 2015, Pages 1482-1494

A universal and robust integrated platform for the scalable production of human cardiomyocytes from pluripotent stem cells

(19)  Fonoudi, Hananeh a,c,e   Ansari, Hassan a   Abbasalizadeh, Saeed a   Larijani, Mehran Rezaei a   Kiani, Sahar a   Hashemizadeh, Shiva a   Zarchi, Ali Sharifi a   Bosman, Alexis c,e   Blue, Gillian M g,h,i   Pahlavan, Sara a   Perry, Matthew d,e   Orr, Yishay g,h   Mayorchak, Yaroslav h   Vandenberg, Jamie d,e   Talkhabi, Mahmood a   Winlaw, David S g,h,i   Harvey, Richard P c,e,f   Aghdami, Nasser a   Baharvand, Hossein a,b  


Author keywords

Bioreactor; Cardiomyocytes; Cell therapy; Directed differentiation; Embryonic stem; Human pluripotent stem cells; Induced pluripotent stem; Small molecules

Indexed keywords

TRANSFORMING GROWTH FACTOR BETA; DIFFERENTIATION ANTIGEN;

EID: 84949676048     PISSN: 21576564     EISSN: 21576580     Source Type: Journal    
DOI: 10.5966/sctm.2014-0275     Document Type: Article
Times cited : (109)

References (49)
  • 1
    • 0032491416 scopus 로고    scopus 로고
    • Embryonic stem cell lines derived from human blastocysts
    • Thomson JA, Itskovitz-Eldor J, Shapiro SS et al. Embryonic stem cell lines derived from human blastocysts. Science 1998;282:1145–1147.
    • (1998) Science , vol.282 , pp. 1145-1147
    • Thomson, J.A.1    Itskovitz-Eldor, J.2    Shapiro, S.S.3
  • 2
    • 36749043230 scopus 로고    scopus 로고
    • Induced pluripotent stem cell lines derived from human somatic cells
    • Yu J, Vodyanik MA, Smuga-Otto K et al. Induced pluripotent stem cell lines derived from human somatic cells. Science 2007;318:1917–1920.
    • (2007) Science , vol.318 , pp. 1917-1920
    • Yu, J.1    Vodyanik, M.A.2    Smuga-Otto, K.3
  • 3
    • 0034904645 scopus 로고    scopus 로고
    • Human embryonic stem cells can differentiate into myocytes with structural and functional properties of cardiomyocytes
    • Kehat I, Kenyagin-Karsenti D, Snir M et al. Human embryonic stem cells can differentiate into myocytes with structural and functional properties of cardiomyocytes. J Clin Invest 2001;108:407–414.
    • (2001) J Clin Invest , vol.108 , pp. 407-414
    • Kehat, I.1    Kenyagin-Karsenti, D.2    Snir, M.3
  • 4
    • 0038210217 scopus 로고    scopus 로고
    • Differentiation of human embryonic stem cells to cardiomyocytes: Role of coculture with visceral endoderm-like cells
    • Mummery C, Ward-van Oostwaard D, Doevendans P et al. Differentiation of human embryonic stem cells to cardiomyocytes: Role of coculture with visceral endoderm-like cells. Circulation 2003;107:2733–2740.
    • (2003) Circulation , vol.107 , pp. 2733-2740
    • Mummery, C.1    Ward-Van Oostwaard, D.2    Doevendans, P.3
  • 5
    • 34948891467 scopus 로고    scopus 로고
    • Cardiomyocytes derived from human embryonic stem cells in pro-survival factors enhance function of infarcted rat hearts
    • Laflamme MA, Chen KY, Naumova AV et al. Cardiomyocytes derived from human embryonic stem cells in pro-survival factors enhance function of infarcted rat hearts. Nat Biotechnol 2007; 25:1015–1024.
    • (2007) Nat Biotechnol , vol.25 , pp. 1015-1024
    • Laflamme, M.A.1    Chen, K.Y.2    Naumova, A.V.3
  • 6
    • 84873873197 scopus 로고    scopus 로고
    • ISL1 protein transduction promotes cardiomyocyte differentiation from human embryonic stem cells
    • Fonoudi H, Yeganeh M, Fattahi F et al. ISL1 protein transduction promotes cardiomyocyte differentiation from human embryonic stem cells. PLoS One 2013;8: e55577.
    • (2013) Plos One , vol.8
    • Fonoudi, H.1    Yeganeh, M.2    Fattahi, F.3
  • 7
    • 56349150327 scopus 로고    scopus 로고
    • Human embryonic stem cells and cardiac repair
    • Zhu WZ, Hauch KD, Xu C et al. Human embryonic stem cells and cardiac repair. Transplant Rev (Orlando) 2009;23:53–68.
    • (2009) Transplant Rev (Orlando) , vol.23 , pp. 53-68
    • Zhu, W.Z.1    Hauch, K.D.2    Xu, C.3
  • 8
    • 84872013374 scopus 로고    scopus 로고
    • Adapting human pluripotent stem cells to high-throughput and high-content screening
    • Desbordes SC, Studer L. Adapting human pluripotent stem cells to high-throughput and high-content screening. Nat Protoc 2013;8: 111–130.
    • (2013) Nat Protoc , vol.8 , pp. 111-130
    • Desbordes, S.C.1    Studer, L.2
  • 9
    • 84905242471 scopus 로고    scopus 로고
    • Chemically defined generation of human cardiomyocytes
    • Burridge PW, Matsa E, Shukla P et al. Chemically defined generation of human cardiomyocytes. Nat Methods 2014;11:855–860.
    • (2014) Nat Methods , vol.11 , pp. 855-860
    • Burridge, P.W.1    Matsa, E.2    Shukla, P.3
  • 10
    • 84892752194 scopus 로고    scopus 로고
    • Small molecule-mediated directed differentiation of human embryonic stem cells toward ventricular cardiomyocytes
    • Karakikes I, Senyei GD, Hansen J et al. Small molecule-mediated directed differentiation of human embryonic stem cells toward ventricular cardiomyocytes. STEM CELLS TRANSLATIONAL MEDICINE 2014;3:18–31.
    • (2014) STEM CELLS TRANSLATIONAL MEDICINE , vol.3 , pp. 18-31
    • Karakikes, I.1    Senyei, G.D.2    Hansen, J.3
  • 11
    • 79960481605 scopus 로고    scopus 로고
    • Chemical strategies for stem cell biology and regenerative medicine
    • Zhu S, Wei W, Ding S. Chemical strategies for stem cell biology and regenerative medicine. Annu Rev Biomed Eng 2011;13:73–90.
    • (2011) Annu Rev Biomed Eng , vol.13 , pp. 73-90
    • Zhu, S.1    Wei, W.2    Ding, S.3
  • 12
    • 84874669151 scopus 로고    scopus 로고
    • Small molecules, big roles—The chemical manipulation of stem cell fate and somatic cell reprogramming
    • Zhang Y, Li W, Laurent T et al. Small molecules, big roles—The chemical manipulation of stem cell fate and somatic cell reprogramming. J Cell Sci 2012;125:5609–5620.
    • (2012) J Cell Sci , vol.125 , pp. 5609-5620
    • Zhang, Y.1    Li, W.2    Laurent, T.3
  • 13
    • 79952114597 scopus 로고    scopus 로고
    • Small molecules in cellular reprogramming and differentiation
    • Yuan X, Li W, Ding S. Small molecules in cellular reprogramming and differentiation. Prog Drug Res 2011;67:253–266.
    • (2011) Prog Drug Res , vol.67 , pp. 253-266
    • Yuan, X.1    Li, W.2    Ding, S.3
  • 14
    • 81255179215 scopus 로고    scopus 로고
    • Stepwise chemically induced cardiomyocyte specification of human embryonic stem cells
    • Gonzalez R, Lee JW, Schultz PG. Stepwise chemically induced cardiomyocyte specification of human embryonic stem cells. Angew Chem Int Ed Engl 2011;50:11181–11185.
    • (2011) Angew Chem Int Ed Engl , vol.50 , pp. 11181-11185
    • Gonzalez, R.1    Lee, J.W.2    Schultz, P.G.3
  • 15
    • 84863560929 scopus 로고    scopus 로고
    • Robust cardiomyocytedifferentiationfromhumanpluripotent stem cells via temporal modulation of canonical Wnt signaling
    • Lian X, Hsiao C, Wilson G et al. Robust cardiomyocytedifferentiationfromhumanpluripotent stem cells via temporal modulation of canonical Wnt signaling. Proc Natl Acad Sci USA 2012;109: E1848–E1857.
    • (2012) Proc Natl Acad Sci USA , vol.109 , pp. E1848-E1857
    • Lian, X.1    Hsiao, C.2    Wilson, G.3
  • 16
    • 84870421675 scopus 로고    scopus 로고
    • A small molecule that promotes cardiac differentiation of human pluripotent stem cells under defined, cytokine- and xeno-free conditions
    • Minami I, Yamada K, Otsuji TG et al. A small molecule that promotes cardiac differentiation of human pluripotent stem cells under defined, cytokine- and xeno-free conditions. Cell Reports 2012;2:1448–1460.
    • (2012) Cell Reports , vol.2 , pp. 1448-1460
    • Minami, I.1    Yamada, K.2    Otsuji, T.G.3
  • 17
    • 84859188483 scopus 로고    scopus 로고
    • Scalable GMP compliant suspension culture system for human ES cells
    • Chen VC, Couture SM, Ye J et al. Scalable GMP compliant suspension culture system for human ES cells. Stem Cell Res (Amst) 2012;8: 388–402.
    • (2012) Stem Cell Res (Amst) , vol.8 , pp. 388-402
    • Chen, V.C.1    Couture, S.M.2    Ye, J.3
  • 18
    • 77952429809 scopus 로고    scopus 로고
    • Upscaling single cell-inoculated suspension culture of human embryonic stem cells
    • Singh H, Mok P, Balakrishnan T et al. Upscaling single cell-inoculated suspension culture of human embryonic stem cells. Stem Cell Res (Amst) 2010;4:165–179.
    • (2010) Stem Cell Res (Amst) , vol.4 , pp. 165-179
    • Singh, H.1    Mok, P.2    Balakrishnan, T.3
  • 19
    • 78649649709 scopus 로고    scopus 로고
    • Scalable platform for human embryonic stem cell differentiation to cardiomyocytes in suspended microcarrier cultures
    • Lecina M, Ting S, Choo A et al. Scalable platform for human embryonic stem cell differentiation to cardiomyocytes in suspended microcarrier cultures. Tissue Eng Part C Methods 2010;16:1609–1619.
    • (2010) Tissue Eng Part C Methods , vol.16 , pp. 1609-1619
    • Lecina, M.1    Ting, S.2    Choo, A.3
  • 20
    • 58249090413 scopus 로고    scopus 로고
    • Generation of human embryonic stem cell-derived mesoderm and cardiac cells using size-specified aggregates in an oxygen-controlled bioreactor
    • Niebruegge S, Bauwens CL, Peerani R et al. Generation of human embryonic stem cell-derived mesoderm and cardiac cells using size-specified aggregates in an oxygen-controlled bioreactor. Biotechnol Bioeng 2009;102:493–507.
    • (2009) Biotechnol Bioeng , vol.102 , pp. 493-507
    • Niebruegge, S.1    Bauwens, C.L.2    Peerani, R.3
  • 21
    • 79960832802 scopus 로고    scopus 로고
    • Geometric control of cardiomyogenic induction in human pluripotent stem cells
    • Bauwens CL, Song H, Thavandiran N et al. Geometric control of cardiomyogenic induction in human pluripotent stem cells. Tissue Eng Part A 2011;17:1901–1909.
    • (2011) Tissue Eng Part A , vol.17 , pp. 1901-1909
    • Bauwens, C.L.1    Song, H.2    Thavandiran, N.3
  • 22
    • 70350126572 scopus 로고    scopus 로고
    • Microwell-mediated control of embryoid body size regulatesembryonic stemcell fate via differential expression of WNT5a and WNT11
    • Hwang YS, Chung BG, Ortmann D et al. Microwell-mediated control of embryoid body size regulatesembryonic stemcell fate via differential expression of WNT5a and WNT11. Proc Natl Acad Sci USA 2009;106:16978–16983.
    • (2009) Proc Natl Acad Sci USA , vol.106 , pp. 16978-16983
    • Hwang, Y.S.1    Chung, B.G.2    Ortmann, D.3
  • 23
    • 84924220178 scopus 로고    scopus 로고
    • Microscale generation of cardiospheres promotes robust enrichment of cardiomyocytes derived from human pluripotent stem cells
    • Nguyen DC, Hookway TA, Wu Q et al. Microscale generation of cardiospheres promotes robust enrichment of cardiomyocytes derived from human pluripotent stem cells. Stem Cell Rep 2014;3:260–268.
    • (2014) Stem Cell Rep , vol.3 , pp. 260-268
    • Nguyen, D.C.1    Hookway, T.A.2    Wu, Q.3
  • 24
    • 84923796564 scopus 로고    scopus 로고
    • Controlling expansion and cardiomyogenic differentiation of human pluripotent stem cells in scalable suspension culture
    • Kempf H, Olmer R, Kropp C et al. Controlling expansion and cardiomyogenic differentiation of human pluripotent stem cells in scalable suspension culture. Stem Cell Rep 2014;3:1132–1146.
    • (2014) Stem Cell Rep , vol.3 , pp. 1132-1146
    • Kempf, H.1    Olmer, R.2    Kropp, C.3
  • 25
    • 84913525381 scopus 로고    scopus 로고
    • A massive suspension culture system with metabolic purification for human pluripotent stem cell-derived cardiomyocytes
    • Hemmi N, Tohyama S, Nakajima K et al. A massive suspension culture system with metabolic purification for human pluripotent stem cell-derived cardiomyocytes. STEM CELLS TRANSLATIONAL MEDICINE 2014;3:1473–1483.
    • (2014) STEM CELLS TRANSLATIONAL MEDICINE , vol.3 , pp. 1473-1483
    • Hemmi, N.1    Tohyama, S.2    Nakajima, K.3
  • 26
    • 84863424794 scopus 로고    scopus 로고
    • Suspendedinculture—Human pluripotent cells for scalable technologies
    • O’Brien C, Laslett AL. Suspendedinculture—Human pluripotent cells for scalable technologies. Stem Cell Res (Amst) 2012;9:167–170.
    • (2012) Stem Cell Res (Amst) , vol.9 , pp. 167-170
    • O’Brien, C.1    Laslett, A.L.2
  • 27
    • 84868016949 scopus 로고    scopus 로고
    • Bioprocess development for mass production of size-controlled human pluripotent stem cell aggregates in stirred suspension bioreactor
    • Abbasalizadeh S, Larijani MR, Samadian A et al. Bioprocess development for mass production of size-controlled human pluripotent stem cell aggregates in stirred suspension bioreactor. Tissue Eng Part C Methods 2012;18:831–851.
    • (2012) Tissue Eng Part C Methods , vol.18 , pp. 831-851
    • Abbasalizadeh, S.1    Larijani, M.R.2    Samadian, A.3
  • 28
    • 84885108863 scopus 로고    scopus 로고
    • Generation of functional hepatocyte-like cells from human pluripotent stem cells in a scalable suspension culture
    • Vosough M, Omidinia E, Kadivar M et al. Generation of functional hepatocyte-like cells from human pluripotent stem cells in a scalable suspension culture. Stem Cells Dev 2013;22:2693–2705.
    • (2013) Stem Cells Dev , vol.22 , pp. 2693-2705
    • Vosough, M.1    Omidinia, E.2    Kadivar, M.3
  • 29
    • 84872048038 scopus 로고    scopus 로고
    • Distinct metabolic flow enables large-scale purification of mouse and human pluripotent stem cell-derived cardiomyocytes
    • Tohyama S, Hattori F, Sano M et al. Distinct metabolic flow enables large-scale purification of mouse and human pluripotent stem cell-derived cardiomyocytes. Cell Stem Cell 2013;12:127–137.
    • (2013) Cell Stem Cell , vol.12 , pp. 127-137
    • Tohyama, S.1    Hattori, F.2    Sano, M.3
  • 30
    • 33644774914 scopus 로고    scopus 로고
    • Generation of new human embryonic stem cell lines with diploid and triploid karyotypes
    • Baharvand H, Ashtiani SK, Taee A et al. Generation of new human embryonic stem cell lines with diploid and triploid karyotypes. Dev Growth Differ 2006;48:117–128.
    • (2006) Dev Growth Differ , vol.48 , pp. 117-128
    • Baharvand, H.1    Ashtiani, S.K.2    Taee, A.3
  • 31
    • 84885145137 scopus 로고    scopus 로고
    • Enhanced generation of human embryonic stem cells from single blastomeres of fair and poor-quality cleavage embryos via inhibition of glycogen synthase kinase b and Rho-associated kinase signaling
    • Taei A, Hassani SN, Eftekhari-Yazdi P et al. Enhanced generation of human embryonic stem cells from single blastomeres of fair and poor-quality cleavage embryos via inhibition of glycogen synthase kinase b and Rho-associated kinase signaling.HumReprod 2013;28:2661–2671.
    • (2013) .Humreprod , vol.28 , pp. 2661-2671
    • Taei, A.1    Hassani, S.N.2    Eftekhari-Yazdi, P.3
  • 32
    • 79960302745 scopus 로고    scopus 로고
    • Long-term maintenance of undifferentiated human embryonic and induced pluripotent stemcells in suspension
    • Larijani MR, Seifinejad A, Pournasr B et al. Long-term maintenance of undifferentiated human embryonic and induced pluripotent stemcells in suspension. Stem Cells Dev 2011;20:1911–1923.
    • (2011) Stem Cells Dev , vol.20 , pp. 1911-1923
    • Larijani, M.R.1    Seifinejad, A.2    Pournasr, B.3
  • 33
    • 0030305457 scopus 로고    scopus 로고
    • A language and environment for statistical computing
    • Ihaka R, Gentleman RR. A language and environment for statistical computing. J Comput Graph Stat 1996;5:299–314.
    • (1996) J Comput Graph Stat , vol.5 , pp. 299-314
    • Ihaka, R.1    Gentleman, R.R.2
  • 35
    • 84942374527 scopus 로고    scopus 로고
    • Improvement of acquisition and analysis methods in multi-electrode array experiments with iPS cell-derived cardiomyocytes
    • Asakura K, Hayashi S, Ojima A et al. Improvement of acquisition and analysis methods in multi-electrode array experiments with iPS cell-derived cardiomyocytes. J Pharmacol Toxicol Methods 2015 [Epub ahead of print].
    • (2015) J Pharmacol Toxicol Methods
    • Asakura, K.1    Hayashi, S.2    Ojima, A.3
  • 36
    • 83755195408 scopus 로고    scopus 로고
    • In vitro modeling of ryanodine receptor 2 dysfunction using human induced pluripotent stem cells
    • Fatima A, Xu G, Shao K et al. In vitro modeling of ryanodine receptor 2 dysfunction using human induced pluripotent stem cells. Cell Physiol Biochem 2011;28:579–592.
    • (2011) Cell Physiol Biochem , vol.28 , pp. 579-592
    • Fatima, A.1    Xu, G.2    Shao, K.3
  • 37
    • 84892429611 scopus 로고    scopus 로고
    • The disease-specific phenotype in cardiomyocytes derived from induced pluripotent stem cells of two long QT syndrome type 3 patients
    • Fatima A, Kaifeng S, Dittmann S et al. The disease-specific phenotype in cardiomyocytes derived from induced pluripotent stem cells of two long QT syndrome type 3 patients. PLoS One 2013;8:e83005.
    • (2013) Plos One , vol.8
    • Fatima, A.1    Kaifeng, S.2    Dittmann, S.3
  • 38
    • 84861345298 scopus 로고    scopus 로고
    • Process engineering of humanpluripotent stem cells for clinical application
    • Serra M, Brito C, Correia C et al. Process engineering of humanpluripotent stem cells for clinical application. Trends Biotechnol 2012;30: 350–359.
    • (2012) Trends Biotechnol , vol.30 , pp. 350-359
    • Serra, M.1    Brito, C.2    Correia, C.3
  • 39
    • 34250802982 scopus 로고    scopus 로고
    • Biphasic role for Wnt/beta-catenin signaling in cardiac specification in zebrafish and embryonic stem cells
    • Ueno S, Weidinger G, Osugi T et al. Biphasic role for Wnt/beta-catenin signaling in cardiac specification in zebrafish and embryonic stem cells. Proc Natl Acad Sci USA 2007;104: 9685–9690.
    • (2007) Proc Natl Acad Sci USA , vol.104 , pp. 9685-9690
    • Ueno, S.1    Weidinger, G.2    Osugi, T.3
  • 40
    • 84867028809 scopus 로고    scopus 로고
    • EndogenousWnt signalling in human embryonic stem cells generates an equilibrium of distinct lineage-specified progenitors
    • Blauwkamp TA, Nigam S, Ardehali R et al. EndogenousWnt signalling in human embryonic stem cells generates an equilibrium of distinct lineage-specified progenitors. Nat Commun 2012;3:1070.
    • (2012) Nat Commun , vol.3 , pp. 1070
    • Blauwkamp, T.A.1    Nigam, S.2    Ardehali, R.3
  • 41
    • 34147124971 scopus 로고    scopus 로고
    • Improved human embryonic stem cell embryoid body homogeneity and cardiomyocyte differentiation from a novel V-96 plate aggregation system highlights interline variability
    • Burridge PW, Anderson D, Priddle H et al. Improved human embryonic stem cell embryoid body homogeneity and cardiomyocyte differentiation from a novel V-96 plate aggregation system highlights interline variability. STEM CELLS 2007;25: 929–938.
    • (2007) STEM CELLS , vol.25 , pp. 929-938
    • Burridge, P.W.1    Erson, D.2    Priddle, H.3
  • 42
    • 73249125581 scopus 로고    scopus 로고
    • The microwell control of embryoid body size in order to regulate cardiac differentiation of human embryonic stem cells
    • Mohr JC, Zhang J, Azarin SM et al. The microwell control of embryoid body size in order to regulate cardiac differentiation of human embryonic stem cells. Biomaterials 2010;31: 1885–1893.
    • (2010) Biomaterials , vol.31 , pp. 1885-1893
    • Mohr, J.C.1    Zhang, J.2    Azarin, S.M.3
  • 43
    • 84919770033 scopus 로고    scopus 로고
    • Combining hypoxia and bioreactor hydrodynamics boosts induced pluripotent stem cell differentiation towards cardiomyocytes
    • Correia C, Serra M, Espinha N et al. Combining hypoxia and bioreactor hydrodynamics boosts induced pluripotent stem cell differentiation towards cardiomyocytes. Stem Cell Rev 2014;10:786–801.
    • (2014) Stem Cell Rev , vol.10 , pp. 786-801
    • Correia, C.1    Serra, M.2    Espinha, N.3
  • 44
    • 84857643783 scopus 로고    scopus 로고
    • Embryonic stem cell trials for macular degeneration: A preliminary report
    • Schwartz SD, Hubschman JP, Heilwell G et al. Embryonic stem cell trials for macular degeneration: A preliminary report. Lancet 2012; 379:713–720.
    • (2012) Lancet , vol.379 , pp. 713-720
    • Schwartz, S.D.1    Hubschman, J.P.2    Heilwell, G.3
  • 45
    • 84923014395 scopus 로고    scopus 로고
    • Human embryonic stem cell-derived retinal pigment epithelium in patients with agerelatedmacular degeneration and Stargardt’s macular dystrophy: Follow-up of two openlabel phase 1/2 studies
    • Schwartz SD, Regillo CD, Lam BL et al. Human embryonic stem cell-derived retinal pigment epithelium in patients with agerelatedmacular degeneration and Stargardt’s macular dystrophy: Follow-up of two openlabel phase 1/2 studies. Lancet 2015;385: 509–516.
    • (2015) Lancet , vol.385 , pp. 509-516
    • Schwartz, S.D.1    Regillo, C.D.2    Lam, B.L.3
  • 46
    • 84929295709 scopus 로고    scopus 로고
    • Treatment of macular degeneration using embryonic stem cell-derived retinal pigment epithelium: Preliminary results in Asian patients
    • Song WK, Park KM, Kim HJ et al. Treatment of macular degeneration using embryonic stem cell-derived retinal pigment epithelium: Preliminary results in Asian patients. Stem Cell Rep 2015;4:860–872.
    • (2015) Stem Cell Rep , vol.4 , pp. 860-872
    • Song, W.K.1    Park, K.M.2    Kim, H.J.3
  • 47
    • 84907752479 scopus 로고    scopus 로고
    • Japan stem-cell trial stirs envy
    • Reardon S, Cyranoski D. Japan stem-cell trial stirs envy. Nature 2014;513:287–288.
    • (2014) Nature , vol.513 , pp. 287-288
    • Reardon, S.1    Cyranoski, D.2
  • 48
    • 84897864670 scopus 로고    scopus 로고
    • Modeling inherited cardiac disorders
    • Sallam K, Kodo K, Wu JC. Modeling inherited cardiac disorders. Circ J 2014;78: 784–794.
    • (2014) Circ J , vol.78 , pp. 784-794
    • Sallam, K.1    Kodo, K.2    Wu, J.C.3
  • 49
    • 84975191940 scopus 로고    scopus 로고
    • Cardiac diseasemodeling using induced pluripotent stemcell-derived human cardiomyocytes
    • Dell’Era P, Benzoni P, Crescini E et al. Cardiac diseasemodeling using induced pluripotent stemcell-derived human cardiomyocytes.World J Stem Cells 2015;7:329–342.
    • (2015) World J Stem Cells , vol.7 , pp. 329-342
    • Dell’Era, P.1    Benzoni, P.2    Crescini, E.3


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