Sensitivity of neural stem cell survival, differentiation and neurite outgrowth within 3D hydrogels to environmental heavy metals

Toxicology Letters

Volumn 242, Issue , 2016, Pages 9-22

  Tasneem, Sameera ^a   Farrell, Kurt ^a   Lee, Moo Yeal ^a   Kothapalli, Chandrasekhar R ^a  

^a Cleveland State University   (United States)

Author keywords

3D cultures; Heavy metals; Mechanistic pathways; Neural stem cells; Neurotoxicity

Indexed keywords

CADMIUM; COLONY STIMULATING FACTOR 1; EOTAXIN; GAMMA INTERFERON; GAMMA INTERFERON INDUCIBLE PROTEIN 10; GRANULOCYTE COLONY STIMULATING FACTOR; GRANULOCYTE MACROPHAGE COLONY STIMULATING FACTOR; INTERLEUKIN 10; INTERLEUKIN 12P40; INTERLEUKIN 12P70; INTERLEUKIN 13; INTERLEUKIN 15; INTERLEUKIN 17; INTERLEUKIN 1ALPHA; INTERLEUKIN 1BETA; INTERLEUKIN 2; INTERLEUKIN 3; INTERLEUKIN 4; INTERLEUKIN 5; INTERLEUKIN 6; INTERLEUKIN 7; INTERLEUKIN 9; LEAD; MACROPHAGE INFLAMMATORY PROTEIN 1ALPHA; MACROPHAGE INFLAMMATORY PROTEIN 1BETA; MERCURY; MONOCYTE CHEMOTACTIC PROTEIN 1; RANTES; TUMOR NECROSIS FACTOR ALPHA; VASCULOTROPIN; CADMIUM CHLORIDE; CHEMOKINE; COLLAGEN TYPE 1; CYTOKINE; HYDROGEL; LEAD ACETATE; MERCURIC CHLORIDE; ORGANOMETALLIC COMPOUND;

ANIMAL CELL; ARTICLE; CELL DIFFERENTIATION; CELL MEMBRANE PERMEABILITY; CELL SURVIVAL; CELL VIABILITY; CYTOKINE RELEASE; CYTOTOXICITY; DNA DAMAGE; DOPAMINERGIC NERVE CELL; EMBRYONIC STEM CELL; EXPOSURE; HYDROGEL; MITOCHONDRIAL MEMBRANE POTENTIAL; MOUSE; NERVE FIBER GROWTH; NEURAL STEM CELL; NONHUMAN; PRIORITY JOURNAL; ANIMAL; BIOMIMETICS; CELL CULTURE; CELL CULTURE TECHNIQUE; COMPARATIVE STUDY; DOSE RESPONSE; DRUG EFFECTS; GLIA; METABOLISM; MOTONEURON; NERVOUS SYSTEM DEVELOPMENT; NEURITE; PATHOLOGY; PHENOTYPE; TIME FACTOR;

ANIMALS; BIOMIMETICS; CADMIUM CHLORIDE; CELL CULTURE TECHNIQUES; CELL SURVIVAL; CELLS, CULTURED; CHEMOKINES; COLLAGEN TYPE I; CYTOKINES; DOPAMINERGIC NEURONS; DOSE-RESPONSE RELATIONSHIP, DRUG; HYDROGELS; MERCURIC CHLORIDE; MICE; MOTOR NEURONS; NEURAL STEM CELLS; NEURITES; NEUROGENESIS; NEUROGLIA; ORGANOMETALLIC COMPOUNDS; PHENOTYPE; TIME FACTORS;

EID: 84949639174     PISSN: 03784274     EISSN: 18793169     Source Type: Journal    
DOI: 10.1016/j.toxlet.2015.11.021     Document Type: Article

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