Neuroprotection by Kukoamine A against oxidative stress may involve N-methyl-d-aspartate receptors

Biochimica et Biophysica Acta - General Subjects

Volumn 1850, Issue 2, 2015, Pages 287-298

  Hu, Xiao Long ^a,b   Gao, Ling Yue ^b   Niu, Yi Xuan ^b   Tian, Xing ^b   Wang, Jian ^b   Meng, Wei Hong ^b   Zhang, Qiao ^b   Cui, Can ^b   Han, Lu ^b   Zhao, Qing Chun ^a  

^a GENERAL HOSPITAL OF NORTHERN THEATER COMMAND   (China)

^b SHENYANG PHARMACEUTICAL UNIVERSITY   (China)

Author keywords

Hydrogen peroxide; Kukoamine A; Molecular docking; Neuroprotection; NMDA; SH SY5Y

Indexed keywords

CALCIUM ION; CYCLIC AMP RESPONSIVE ELEMENT BINDING PROTEIN; KUKOAMINE A; LACTATE DEHYDROGENASE; LIPOCORTIN 5; MALONALDEHYDE; MITOGEN ACTIVATED PROTEIN KINASE 1; MITOGEN ACTIVATED PROTEIN KINASE 3; MITOGEN ACTIVATED PROTEIN KINASE P38; N METHYL DEXTRO ASPARTIC ACID RECEPTOR; N METHYL DEXTRO ASPARTIC ACID RECEPTOR 2A; N METHYL DEXTRO ASPARTIC ACID RECEPTOR 2B; N METHYL DEXTRO ASPARTIC ACID RECEPTOR BLOCKING AGENT; NEUROPROTECTIVE AGENT; PROCASPASE 3; PROCASPASE 9; PROTEIN BAX; PROTEIN BCL 2; PROTEIN KINASE B; PROTEIN P53; REACTIVE OXYGEN METABOLITE; SUPEROXIDE DISMUTASE; UNCLASSIFIED DRUG; APOPTOSIS REGULATORY PROTEIN; CALCIUM; HYDROGEN PEROXIDE; OXIDIZING AGENT; SPERMINE;

ANTIOXIDANT ACTIVITY; APOPTOSIS; ARTICLE; BRAIN INJURY; CALCIUM CELL LEVEL; CALCIUM TRANSPORT; CELL SURVIVAL; CELL VIABILITY; CONCENTRATION RESPONSE; CONFOCAL MICROSCOPY; CONTROLLED STUDY; DRUG MECHANISM; DRUG SCREENING; ENZYME ACTIVITY; ENZYME RELEASE; FLOW CYTOMETRY; HUMAN; HUMAN CELL; MITOCHONDRIAL MEMBRANE POTENTIAL; MOLECULAR DOCKING; MTT ASSAY; NEUROPROTECTION; OXIDATIVE STRESS; PROTEIN EXPRESSION; RECEPTOR BLOCKING; STAINING; VIRTUAL REALITY; WESTERN BLOTTING; ANALOGS AND DERIVATIVES; ANTAGONISTS AND INHIBITORS; BRAIN INJURIES; DRUG EFFECTS; METABOLISM; PATHOLOGY; TUMOR CELL LINE;

APOPTOSIS; APOPTOSIS REGULATORY PROTEINS; BRAIN INJURIES; CALCIUM; CELL LINE, TUMOR; HUMANS; HYDROGEN PEROXIDE; L-LACTATE DEHYDROGENASE; MALONDIALDEHYDE; NEUROPROTECTIVE AGENTS; OXIDANTS; OXIDATIVE STRESS; RECEPTORS, N-METHYL-D-ASPARTATE; SPERMINE; SUPEROXIDE DISMUTASE;

EID: 84911930888     PISSN: 03044165     EISSN: 18728006     Source Type: Journal    
DOI: 10.1016/j.bbagen.2014.11.006     Document Type: Article

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