Neuroprotective effects of Arctium lappa L. roots against glutamate-induced oxidative stress by inhibiting phosphorylation of p38, JNK and ERK 1/2 MAPKs in PC12 cells

Environmental Toxicology and Pharmacology

Volumn 38, Issue 1, 2014, Pages 189-198

  Tian, Xing ^a,b   Sui, Shuang ^a   Huang, Jin ^a   Bai, Jun Peng ^a   Ren, Tian Shu ^b   Zhao, Qing Chun ^a,b  

^a SHENYANG PHARMACEUTICAL UNIVERSITY   (China)

^b GENERAL HOSPITAL OF NORTHERN THEATER COMMAND   (China)

Author keywords

Arctium lappa; Glutamate; Neuroprotection; Oxidative stress; PC12 cells

Indexed keywords

ACETIC ACID ETHYL ESTER; ARCTIUM LAPPA EXTRACT; CASPASE 3; CYTOCHROME C; GLUTAMIC ACID; GLUTATHIONE PEROXIDASE; LACTATE DEHYDROGENASE; MITOGEN ACTIVATED PROTEIN KINASE 1; MITOGEN ACTIVATED PROTEIN KINASE 3; MITOGEN ACTIVATED PROTEIN KINASE P38; NEUROPROTECTIVE AGENT; PLANT EXTRACT; PROTEIN BAX; PROTEIN BCL 2; REACTIVE OXYGEN METABOLITE; STRESS ACTIVATED PROTEIN KINASE; SUPEROXIDE DISMUTASE; UNCLASSIFIED DRUG; ACETIC ACID DERIVATIVE; BAX PROTEIN, RAT; CASP3 PROTEIN, RAT; MALONALDEHYDE; MITOGEN ACTIVATED PROTEIN KINASE; SOLVENT;

ANTIOXIDANT ACTIVITY; ARCTIUM LAPPA; ARTICLE; CELL VIABILITY; CONTROLLED STUDY; CYTOTOXICITY; ENZYME ACTIVITY; ENZYME PHOSPHORYLATION; INHIBITION KINETICS; MITOCHONDRIAL MEMBRANE POTENTIAL; NEUROPROTECTION; OXIDATIVE STRESS; PC12 CELL LINE; PLANT ROOT; PRIORITY JOURNAL; PROTEIN EXPRESSION; SIGNAL TRANSDUCTION; UPREGULATION; WESTERN BLOTTING; ANIMAL; ARCTIUM; CHEMISTRY; DRUG EFFECTS; METABOLISM; PHOSPHORYLATION; RAT;

ACETATES; ANIMALS; ARCTIUM; BCL-2-ASSOCIATED X PROTEIN; CASPASE 3; CYTOCHROMES C; GLUTAMIC ACID; GLUTATHIONE PEROXIDASE; MALONDIALDEHYDE; MITOGEN-ACTIVATED PROTEIN KINASES; NEUROPROTECTIVE AGENTS; OXIDATIVE STRESS; PC12 CELLS; PHOSPHORYLATION; PLANT EXTRACTS; PLANT ROOTS; PROTO-ONCOGENE PROTEINS C-BCL-2; RATS; REACTIVE OXYGEN SPECIES; SOLVENTS; SUPEROXIDE DISMUTASE;

EID: 84904639546     PISSN: 13826689     EISSN: 18727077     Source Type: Journal    
DOI: 10.1016/j.etap.2014.05.017     Document Type: Article

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