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Volumn 11, Issue 1, 2016, Pages 164-170

Bioavailability and safety study of resveratrol 500 mg tablets in healthy male and female volunteers

Author keywords

Absorption; Bioavailability; Metabolism; Resveratrol; Safety; Supplements

Indexed keywords

RESVERATROL;

EID: 84949477526     PISSN: 17920981     EISSN: 17921015     Source Type: Journal    
DOI: 10.3892/etm.2015.2895     Document Type: Article
Times cited : (156)

References (34)
  • 1
    • 0019940467 scopus 로고
    • Effects of stilbene components of the roots of Polygonum cuspidatum Sieb. et Zucc. on lipid metabolism
    • Arichi H, Kimura Y, Okuda H, Baba K, Kozawa M and Arichi S: Effects of stilbene components of the roots of Polygonum cuspidatum Sieb. et Zucc. on lipid metabolism. Chem Pharm Bull (Tokyo) 30: 1766-1770, 1982.
    • (1982) Chem Pharm Bull (Tokyo) , vol.30 , pp. 1766-1770
    • Arichi, H.1    Kimura, Y.2    Okuda, H.3    Baba, K.4    Kozawa, M.5    Arichi, S.6
  • 2
    • 33745962138 scopus 로고    scopus 로고
    • Therapeutic potential of resveratrol: The in vivo evidence
    • Baur JA and Sinclair DA: Therapeutic potential of resveratrol: The in vivo evidence. Nat Rev Drug Discov 5: 493-506, 2006.
    • (2006) Nat Rev Drug Discov , vol.5 , pp. 493-506
    • Baur, J.A.1    Sinclair, D.A.2
  • 4
    • 74949098826 scopus 로고    scopus 로고
    • Grapes, wines, resveratrol, and heart health
    • Bertell AA and Das DK: Grapes, wines, resveratrol, and heart health. J Cardiovasc Pharmacol 54: 468-476 2009.
    • (2009) J Cardiovasc Pharmacol , vol.54 , pp. 468-476
    • Bertell, A.A.1    Das, D.K.2
  • 5
    • 79551557055 scopus 로고    scopus 로고
    • Resveratrol and liver disease: From bench to bedside and community
    • Bishayee A, Darvesh AS, Politis T and McGory R: Resveratrol and liver disease: From bench to bedside and community. Liver Int 30: 1103-1114, 2010.
    • (2010) Liver Int , vol.30 , pp. 1103-1114
    • Bishayee, A.1    Darvesh, A.S.2    Politis, T.3    McGory, R.4
  • 6
    • 84879799217 scopus 로고    scopus 로고
    • Resveratrol metabolites inhibit human metastatic colon cancer cells progression and synergize with chemotherapeutic drugs to induce cell death
    • Aires V, Limagne E, Cotte AK, Latruffe N, Ghiringhelli F and Delmas D: Resveratrol metabolites inhibit human metastatic colon cancer cells progression and synergize with chemotherapeutic drugs to induce cell death. Mol Nutr Food Res 57: 1170-1181, 2013.
    • (2013) Mol Nutr Food Res , vol.57 , pp. 1170-1181
    • Aires, V.1    Limagne, E.2    Cotte, A.K.3    Latruffe, N.4    Ghiringhelli, F.5    Delmas, D.6
  • 7
    • 0346074656 scopus 로고    scopus 로고
    • Cancer chemoprevention by resveratrol: In vitro and in vivo studies and the underlying mechanisms (review)
    • Aziz MH, Kumar R and Ahmad N: Cancer chemoprevention by resveratrol: In vitro and in vivo studies and the underlying mechanisms (review). Int J Oncol 23: 17-28, 2003.
    • (2003) Int J Oncol , vol.23 , pp. 17-28
    • Aziz, M.H.1    Kumar, R.2    Ahmad, N.3
  • 9
    • 0034645693 scopus 로고    scopus 로고
    • Biological effects of resveratrol
    • Frémont L: Biological effects of resveratrol. Life Sci 66: 663-673, 2000.
    • (2000) Life Sci , vol.66 , pp. 663-673
    • Frémont, L.1
  • 10
    • 0034682983 scopus 로고    scopus 로고
    • Cardioprotective effect of resveratrol, a natural antioxidant derived from grapes
    • Hung LM, Chen JK, Huang SS, Lee RS and Su MJ: Cardioprotective effect of resveratrol, a natural antioxidant derived from grapes. Cardiovasc Res 47: 549-555, 2000.
    • (2000) Cardiovasc Res , vol.47 , pp. 549-555
    • Hung, L.M.1    Chen, J.K.2    Huang, S.S.3    Lee, R.S.4    Su, M.J.5
  • 12
    • 20344407841 scopus 로고    scopus 로고
    • Resveratrol as an anti-inflammatory and anti-aging agent: Mechanisms and clinical implications
    • de la Lastra CA and Villegas I: Resveratrol as an anti-inflammatory and anti-aging agent: Mechanisms and clinical implications. Mol Nutr Food Res 49: 405-430, 2005.
    • (2005) Mol Nutr Food Res , vol.49 , pp. 405-430
    • de la Lastra, C.A.1    Villegas, I.2
  • 13
    • 20344401095 scopus 로고    scopus 로고
    • Molecular mechanisms of the chemopreventive effects of resveratrol and its analogs in carcinogenesis
    • Ulrich S, Wolter F and Stein JM: Molecular mechanisms of the chemopreventive effects of resveratrol and its analogs in carcinogenesis. Mol Nutr Food Res 49: 452-461, 2005.
    • (2005) Mol Nutr Food Res , vol.49 , pp. 452-461
    • Ulrich, S.1    Wolter, F.2    Stein, J.M.3
  • 17
    • 0032830226 scopus 로고    scopus 로고
    • Capillary electrophoretic determination of resveratrol in wines
    • Gu X, Creasy L, Kester A and Zeece M: Capillary electrophoretic determination of resveratrol in wines. J Agric Food Chem 47: 3223-3227, 1999.
    • (1999) J Agric Food Chem , vol.47 , pp. 3223-3227
    • Gu, X.1    Creasy, L.2    Kester, A.3    Zeece, M.4
  • 21
    • 84866740513 scopus 로고    scopus 로고
    • Pharmacokinetics of resveratrol metabolic profile in healthy humans after moderate consumption of red wine and grape extract tablets
    • Rotches-Ribalta M, Andres-Lacueva C, Estruch R, Escribano E and Urpi-Sarda M: Pharmacokinetics of resveratrol metabolic profile in healthy humans after moderate consumption of red wine and grape extract tablets. Pharmacol Res 66: 375-382, 2012.
    • (2012) Pharmacol Res , vol.66 , pp. 375-382
    • Rotches-Ribalta, M.1    Andres-Lacueva, C.2    Estruch, R.3    Escribano, E.4    Urpi-Sarda, M.5
  • 22
    • 78549288940 scopus 로고    scopus 로고
    • Repeat dose study of the cancer chemopreventive agent resveratrol in healthy volunteers: Safety, pharmacokinetics, and effect on the insulin-like growth factor axis
    • Brown A, Patel KR, Viskaduraki M, Crowell JA, Perloff M, Booth TD, Vasilinin G, Sen A, Schinas AM, Piccirilli G, et al: Repeat dose study of the cancer chemopreventive agent resveratrol in healthy volunteers: Safety, pharmacokinetics, and effect on the insulin-like growth factor axis. Cancer Res 70: 9003-9011, 2010.
    • (2010) Cancer Res , vol.70 , pp. 9003-9011
    • Brown, A.1    Patel, K.R.2    Viskaduraki, M.3    Crowell, J.A.4    Perloff, M.5    Booth, T.D.6    Vasilinin, G.7    Sen, A.8    Schinas, A.M.9    Piccirilli, G.10
  • 23
    • 28844475210 scopus 로고    scopus 로고
    • Identification of the major metabolites of resveratrol in rat urine by HPLC-MS/MS
    • Wang D, Hang T, Wu C and Liu W: Identification of the major metabolites of resveratrol in rat urine by HPLC-MS/MS. J Chromatogr B Analyt Technol Biomed Life Sci 829: 97-106, 2005.
    • (2005) J Chromatogr B Analyt Technol Biomed Life Sci , vol.829 , pp. 97-106
    • Wang, D.1    Hang, T.2    Wu, C.3    Liu, W.4
  • 24
    • 78851469101 scopus 로고    scopus 로고
    • Bioavailability of resveratrol
    • Walle T: Bioavailability of resveratrol. Ann N Y Acad Sci 1215: 9-15, 2011.
    • (2011) Ann N Y Acad Sci , vol.1215 , pp. 9-15
    • Walle, T.1
  • 25
  • 27
    • 76449091433 scopus 로고    scopus 로고
    • High performance liquid chromatography-tandem mass spectrometric determination of resveratrol and its metabolites in rat tissues
    • Liu X, Teng Z, Zhang Y, Huan M and Zhou S: High performance liquid chromatography-tandem mass spectrometric determination of resveratrol and its metabolites in rat tissues. Anal Lett 43: 557-569, 2010.
    • (2010) Anal Lett , vol.43 , pp. 557-569
    • Liu, X.1    Teng, Z.2    Zhang, Y.3    Huan, M.4    Zhou, S.5
  • 28
    • 82255182998 scopus 로고    scopus 로고
    • Determination of resveratrol and its sulfate and glucuronide metabolites in plasma by LC-MS/MS and their pharmacokinetics in dogs
    • Muzzio M, Huang Z, Hu SC, Johnson WD, McCormick DL and Kapetanovic IM: Determination of resveratrol and its sulfate and glucuronide metabolites in plasma by LC-MS/MS and their pharmacokinetics in dogs. J Pharm Biomed Anal 59: 201-208, 2012.
    • (2012) J Pharm Biomed Anal , vol.59 , pp. 201-208
    • Muzzio, M.1    Huang, Z.2    Hu, S.C.3    Johnson, W.D.4    McCormick, D.L.5    Kapetanovic, I.M.6
  • 29
    • 77957315722 scopus 로고    scopus 로고
    • Determination of quercetin and resveratrol in whole blood-implications for bioavailability studies
    • Biasutto L, Marotta E, Garbisa S, Zoratti M and Paradisi C: Determination of quercetin and resveratrol in whole blood-implications for bioavailability studies. Molecules 15: 6570-6579, 2010.
    • (2010) Molecules , vol.15 , pp. 6570-6579
    • Biasutto, L.1    Marotta, E.2    Garbisa, S.3    Zoratti, M.4    Paradisi, C.5
  • 33
    • 84865181393 scopus 로고    scopus 로고
    • Resveratrol supplementation improves glycemic control in type 2 diabetes mellitus
    • Bhatt JK, Thomas S and Nanjan MJ: Resveratrol supplementation improves glycemic control in type 2 diabetes mellitus. Nutr Res 32: 537-541, 2012.
    • (2012) Nutr Res , vol.32 , pp. 537-541
    • Bhatt, J.K.1    Thomas, S.2    Nanjan, M.J.3
  • 34
    • 84901810516 scopus 로고    scopus 로고
    • Effects of resveratrol on memory performance, hippocampal functional connectivity, and glucose metabolism in healthy older adults
    • Witte AV, Kerti L, Margulies DS and Flöel A: Effects of resveratrol on memory performance, hippocampal functional connectivity, and glucose metabolism in healthy older adults. J Neurosci 34: 7862-7870, 2014.
    • (2014) J Neurosci , vol.34 , pp. 7862-7870
    • Witte, A.V.1    Kerti, L.2    Margulies, D.S.3    Flöel, A.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.