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Volumn 339, Issue , 2016, Pages 40-50

Roles of NMDARs in maintenance of the mouse cerebrovascular endothelial cell-constructed tight junction barrier

Author keywords

BBB; Cerebrovascular endothelial cells; MAPKs; MMPs; NMDA receptor; Occludin tight junction

Indexed keywords

2 (2 AMINO 3 METHOXYPHENYL)CHROMONE; DIZOCILPINE; GELATINASE A; GELATINASE B; MESSENGER RNA; MITOGEN ACTIVATED PROTEIN KINASE 1; MITOGEN ACTIVATED PROTEIN KINASE 3; N METHYL DEXTRO ASPARTIC ACID RECEPTOR; OCCLUDIN; RECEPTOR SUBUNIT; AMINO ACID RECEPTOR BLOCKING AGENT; BLOOD CLOTTING FACTOR 8; DIZOCILPINE MALEATE; GPRIN1 PROTEIN, MOUSE; NERVE PROTEIN; NR2B NMDA RECEPTOR;

EID: 84949446876     PISSN: 0300483X     EISSN: 18793185     Source Type: Journal    
DOI: 10.1016/j.tox.2015.11.006     Document Type: Article
Times cited : (28)

References (53)
  • 2
    • 78651354592 scopus 로고    scopus 로고
    • Functional NMDA receptors with atypical properties are expressed in podocytes
    • Anderson M., Suh J.M., Kim E.Y., Dryer S.E. Functional NMDA receptors with atypical properties are expressed in podocytes. Am. J. Physiol. Cell Physiol. 2011, 300:C22-C32.
    • (2011) Am. J. Physiol. Cell Physiol. , vol.300 , pp. C22-C32
    • Anderson, M.1    Suh, J.M.2    Kim, E.Y.3    Dryer, S.E.4
  • 3
    • 34547113059 scopus 로고    scopus 로고
    • The NMDA and AMPA/KA receptors are involved in glutamate-induced alterations of occludin expression and phosphorylation in brain endothelial cells
    • András I.E., Deli M.A., Veszelka S., Hayashi K., Hennig B., Toborek M. The NMDA and AMPA/KA receptors are involved in glutamate-induced alterations of occludin expression and phosphorylation in brain endothelial cells. J. Cereb. Blood Flow Metab. 2007, 27:1431-1443.
    • (2007) J. Cereb. Blood Flow Metab. , vol.27 , pp. 1431-1443
    • András, I.E.1    Deli, M.A.2    Veszelka, S.3    Hayashi, K.4    Hennig, B.5    Toborek, M.6
  • 4
    • 2342471420 scopus 로고    scopus 로고
    • The blood-brain barrier: an overview: structure, regulation, and clinical implications
    • Ballabh P., Braun A., Nedergaard M. The blood-brain barrier: an overview: structure, regulation, and clinical implications. Neurobiol. Dis. 2004, 16:1-13.
    • (2004) Neurobiol. Dis. , vol.16 , pp. 1-13
    • Ballabh, P.1    Braun, A.2    Nedergaard, M.3
  • 5
    • 0024232895 scopus 로고
    • Absence of N-methyl-d-aspartate receptors on ovine cerebral microvessels
    • Beart P.M., Sheehan K.A., Manallack D.T. Absence of N-methyl-d-aspartate receptors on ovine cerebral microvessels. J. Cereb. Blood Flow Metab. 1988, 8:879-882.
    • (1988) J. Cereb. Blood Flow Metab. , vol.8 , pp. 879-882
    • Beart, P.M.1    Sheehan, K.A.2    Manallack, D.T.3
  • 6
    • 84924762753 scopus 로고    scopus 로고
    • Glutamate efflux at the blood-brain barrier: cellular mechanisms and potential clinical relevance
    • Cederberg-Helms H.C., Uhd-Nielsen C., Brodin B. Glutamate efflux at the blood-brain barrier: cellular mechanisms and potential clinical relevance. Arch. Med. Res. 2014, 45:639-645.
    • (2014) Arch. Med. Res. , vol.45 , pp. 639-645
    • Cederberg-Helms, H.C.1    Uhd-Nielsen, C.2    Brodin, B.3
  • 7
    • 77951429357 scopus 로고    scopus 로고
    • Lipoteichoic acid-induced TNF-α and IL-6 gene expressions and oxidative stress production in macrophages are suppressed by ketamine through downregulating Toll-like receptor 2-mediated activation of ERK1/2 and NFκB
    • Chang H.C., Lin K.H., Tai Y.T., Chen J.T., Chen R.M. Lipoteichoic acid-induced TNF-α and IL-6 gene expressions and oxidative stress production in macrophages are suppressed by ketamine through downregulating Toll-like receptor 2-mediated activation of ERK1/2 and NFκB. Shock 2010, 33:485-492.
    • (2010) Shock , vol.33 , pp. 485-492
    • Chang, H.C.1    Lin, K.H.2    Tai, Y.T.3    Chen, J.T.4    Chen, R.M.5
  • 8
    • 79952195776 scopus 로고    scopus 로고
    • Resveratrol attenuates oxidized LDL-evoked Lox-1 signaling and consequently protects against apoptotic insults to cerebrovascular endothelial cells
    • Chang H.C., Chen T.G., Tai Y.T., Chen T.L., Chiu W.T., Chen R.M. Resveratrol attenuates oxidized LDL-evoked Lox-1 signaling and consequently protects against apoptotic insults to cerebrovascular endothelial cells. J. Cereb. Blood Flow Metab. 2011, 31:842-854.
    • (2011) J. Cereb. Blood Flow Metab. , vol.31 , pp. 842-854
    • Chang, H.C.1    Chen, T.G.2    Tai, Y.T.3    Chen, T.L.4    Chiu, W.T.5    Chen, R.M.6
  • 9
    • 84898977561 scopus 로고    scopus 로고
    • Resveratrol attenuates high-fat diet-induced disruption of the blood-brain barrier and protects brain neurons from apoptotic insults
    • Chang H.C., Tai Y.T., Cherng Y.G., Lin J.W., Liu S.H., Chen T.L., Chen R.M. Resveratrol attenuates high-fat diet-induced disruption of the blood-brain barrier and protects brain neurons from apoptotic insults. J. Agric. Food Chem. 2014, 62:3466-3475.
    • (2014) J. Agric. Food Chem. , vol.62 , pp. 3466-3475
    • Chang, H.C.1    Tai, Y.T.2    Cherng, Y.G.3    Lin, J.W.4    Liu, S.H.5    Chen, T.L.6    Chen, R.M.7
  • 11
    • 0026757051 scopus 로고
    • Activation of MAP kinases by calcium-dependent and calcium-independent pathways. Stimulation by thapsigargin and epidermal growth factor
    • Chao T.S., Byron K.L., Lee K.M., Villereal M., Rosner M.R. Activation of MAP kinases by calcium-dependent and calcium-independent pathways. Stimulation by thapsigargin and epidermal growth factor. J. Biol. Chem. 1992, 267:19876-19883.
    • (1992) J. Biol. Chem. , vol.267 , pp. 19876-19883
    • Chao, T.S.1    Byron, K.L.2    Lee, K.M.3    Villereal, M.4    Rosner, M.R.5
  • 12
    • 0034099223 scopus 로고    scopus 로고
    • Restoration of tight junction structure and barrier function by downregulation of the mitogen-activated protein kinase pathway in ras-transformed Madin-Darby canine kidney cells
    • Chen Y., Lu Q., Schneeberger E.E., Goodenough D.A. Restoration of tight junction structure and barrier function by downregulation of the mitogen-activated protein kinase pathway in ras-transformed Madin-Darby canine kidney cells. Mol. Biol. Cell 2000, 11:849-862.
    • (2000) Mol. Biol. Cell , vol.11 , pp. 849-862
    • Chen, Y.1    Lu, Q.2    Schneeberger, E.E.3    Goodenough, D.A.4
  • 13
    • 18344377024 scopus 로고    scopus 로고
    • Ketamine reduces nitric oxide biosynthesis in human umbilical vein endothelial cells by down-regulating endothelial nitric oxide synthase expression and intracellular calcium levels
    • Chen R.M., Chen T.L., Lin Y.L., Chen T.G., Tai Y.T. Ketamine reduces nitric oxide biosynthesis in human umbilical vein endothelial cells by down-regulating endothelial nitric oxide synthase expression and intracellular calcium levels. Crit. Care Med. 2005, 33:1044-1049.
    • (2005) Crit. Care Med. , vol.33 , pp. 1044-1049
    • Chen, R.M.1    Chen, T.L.2    Lin, Y.L.3    Chen, T.G.4    Tai, Y.T.5
  • 14
    • 33846867270 scopus 로고    scopus 로고
    • Oxidized low-density lipoprotein induces apoptotic insults to mouse cerebral endothelial cells via a Bax-mitochondria-caspase protease pathway
    • Chen T.G., Chen T.L., Chang H.C., Tai Y.T., Cherng Y.G., Chang Y.T., Chen R.M. Oxidized low-density lipoprotein induces apoptotic insults to mouse cerebral endothelial cells via a Bax-mitochondria-caspase protease pathway. Toxicol. Appl. Pharmacol. 2007, 219:42-53.
    • (2007) Toxicol. Appl. Pharmacol. , vol.219 , pp. 42-53
    • Chen, T.G.1    Chen, T.L.2    Chang, H.C.3    Tai, Y.T.4    Cherng, Y.G.5    Chang, Y.T.6    Chen, R.M.7
  • 15
    • 0025265926 scopus 로고
    • The role of glutamate neurotoxicity in hypoxic-ischemic neuronal death
    • Choi D.W., Rothman S.M. The role of glutamate neurotoxicity in hypoxic-ischemic neuronal death. Annu. Rev. Neurosci. 1990, 13:171-182.
    • (1990) Annu. Rev. Neurosci. , vol.13 , pp. 171-182
    • Choi, D.W.1    Rothman, S.M.2
  • 16
    • 84878845628 scopus 로고    scopus 로고
    • MicroRNA-210 targets antiapoptotic Bcl-2 expression and mediates hypoxia-induced apoptosis of neuroblastoma cells
    • Chio C.C., Lin J.W., Cheng H.A., Chiu W.T., Wang Y.H., Wang J.J., Hsing C.H., Chen R.M. MicroRNA-210 targets antiapoptotic Bcl-2 expression and mediates hypoxia-induced apoptosis of neuroblastoma cells. Arch. Toxicol. 2013, 87:458-468.
    • (2013) Arch. Toxicol. , vol.87 , pp. 458-468
    • Chio, C.C.1    Lin, J.W.2    Cheng, H.A.3    Chiu, W.T.4    Wang, Y.H.5    Wang, J.J.6    Hsing, C.H.7    Chen, R.M.8
  • 17
    • 80053390173 scopus 로고    scopus 로고
    • Long term potentiation is impaired in membrane glycoprotein CD200-deficient mice: a role for toll-like receptor activation
    • Costello D.A., Lyons A., Denieffe S., Browne T.C., Cox F.F., Lynch M.A. Long term potentiation is impaired in membrane glycoprotein CD200-deficient mice: a role for toll-like receptor activation. J. Biol. Chem. 2011, 286:34722-34732.
    • (2011) J. Biol. Chem. , vol.286 , pp. 34722-34732
    • Costello, D.A.1    Lyons, A.2    Denieffe, S.3    Browne, T.C.4    Cox, F.F.5    Lynch, M.A.6
  • 18
    • 0020081135 scopus 로고
    • Electrical resistance of brain microvascular endothelium
    • Crone C., Olesen S.P. Electrical resistance of brain microvascular endothelium. Brain Res. 1982, 241:49-55.
    • (1982) Brain Res. , vol.241 , pp. 49-55
    • Crone, C.1    Olesen, S.P.2
  • 20
    • 0242573129 scopus 로고    scopus 로고
    • Development of the blood-brain barrier
    • Engelhardt B. Development of the blood-brain barrier. Cell Tissue Res. 2003, 314:119-129.
    • (2003) Cell Tissue Res. , vol.314 , pp. 119-129
    • Engelhardt, B.1
  • 21
    • 0035906274 scopus 로고    scopus 로고
    • Activation of p44/p42 MAP kinase in striatal neurons via kainate receptors and P13 kinase
    • Fuller G., Veitch K., Ho L.K., Cruise L., Morris B.J. Activation of p44/p42 MAP kinase in striatal neurons via kainate receptors and P13 kinase. Mol. Brain Res. 2001, 89:126-132.
    • (2001) Mol. Brain Res. , vol.89 , pp. 126-132
    • Fuller, G.1    Veitch, K.2    Ho, L.K.3    Cruise, L.4    Morris, B.J.5
  • 22
    • 70450182118 scopus 로고    scopus 로고
    • Coupling of the NMDA receptor to neuroprotective and neurodestructive events
    • Hardingham G.E. Coupling of the NMDA receptor to neuroprotective and neurodestructive events. Biochem. Soc. Trans. 2009, 37:1147-1160.
    • (2009) Biochem. Soc. Trans. , vol.37 , pp. 1147-1160
    • Hardingham, G.E.1
  • 23
    • 70349582346 scopus 로고    scopus 로고
    • The blood-brain barrier and glutamate
    • Hawkins R.A. The blood-brain barrier and glutamate. Am. J. Clin. Nutr. 2009, 90:867S-874S.
    • (2009) Am. J. Clin. Nutr. , vol.90 , pp. 867S-874S
    • Hawkins, R.A.1
  • 24
    • 77957780905 scopus 로고    scopus 로고
    • Progesterone and allopregnanolone attenuate blood-brain barrier dysfunction following permanent focal ischemia by regulating the expression of matrix metalloproteinases
    • Ishrat T., Sayeed I., Atif F., Hua F., Stein D.G. Progesterone and allopregnanolone attenuate blood-brain barrier dysfunction following permanent focal ischemia by regulating the expression of matrix metalloproteinases. Exp. Neurol. 2010, 226:183-190.
    • (2010) Exp. Neurol. , vol.226 , pp. 183-190
    • Ishrat, T.1    Sayeed, I.2    Atif, F.3    Hua, F.4    Stein, D.G.5
  • 25
    • 0035029425 scopus 로고    scopus 로고
    • Cerebral edema
    • Kempski O. Cerebral edema. Semin. Nephrol. 2001, 21:303-307.
    • (2001) Semin. Nephrol. , vol.21 , pp. 303-307
    • Kempski, O.1
  • 28
    • 78649553696 scopus 로고    scopus 로고
    • Resveratrol protects against oxidized LDL-induced breakage of the blood-brain barrier by lessening disruption of tight junctions and apoptotic insults to mouse cerebrovascular endothelial cells
    • Lin Y.L., Chang H.C., Chen T.L., Chang J.H., Chiu W.T., Lin J.W., Chen R.M. Resveratrol protects against oxidized LDL-induced breakage of the blood-brain barrier by lessening disruption of tight junctions and apoptotic insults to mouse cerebrovascular endothelial cells. J. Nutr. 2010, 140:2187-2192.
    • (2010) J. Nutr. , vol.140 , pp. 2187-2192
    • Lin, Y.L.1    Chang, H.C.2    Chen, T.L.3    Chang, J.H.4    Chiu, W.T.5    Lin, J.W.6    Chen, R.M.7
  • 29
    • 79952274662 scopus 로고    scopus 로고
    • Role of rho kinase in microvascular damage following cerebral ischemia reperfusion in rats
    • Liu K., Li Z., Wu T., Ding S. Role of rho kinase in microvascular damage following cerebral ischemia reperfusion in rats. Int. J. Mol. Sci. 2011, 12:1222-1231.
    • (2011) Int. J. Mol. Sci. , vol.12 , pp. 1222-1231
    • Liu, K.1    Li, Z.2    Wu, T.3    Ding, S.4
  • 30
    • 84864760434 scopus 로고    scopus 로고
    • Tight junction in blood-brain barrier: an overview of structure, regulation, and regulator substances
    • Liu W.Y., Wang Z.B., Zhang L.C., Wei X., Li L. Tight junction in blood-brain barrier: an overview of structure, regulation, and regulator substances. CNS Neurosci. Ther. 2012, 18:609-615.
    • (2012) CNS Neurosci. Ther. , vol.18 , pp. 609-615
    • Liu, W.Y.1    Wang, Z.B.2    Zhang, L.C.3    Wei, X.4    Li, L.5
  • 31
    • 0032924640 scopus 로고    scopus 로고
    • Oxidative stress in brain ischemia
    • Love S. Oxidative stress in brain ischemia. Brain Pathol. 1999, 9:119-131.
    • (1999) Brain Pathol. , vol.9 , pp. 119-131
    • Love, S.1
  • 32
    • 33644803284 scopus 로고    scopus 로고
    • Activation of matrix metalloproteinase-9 via neuronal nitric oxide synthase contributes to NMDA-induced retinal ganglion cell death
    • Manabe S.I., Gu Z., Lipton S.A. Activation of matrix metalloproteinase-9 via neuronal nitric oxide synthase contributes to NMDA-induced retinal ganglion cell death. Investig. Ophthalmol. Vis. Sci. 2005, 46:4747-4753.
    • (2005) Investig. Ophthalmol. Vis. Sci. , vol.46 , pp. 4747-4753
    • Manabe, S.I.1    Gu, Z.2    Lipton, S.A.3
  • 33
    • 77956187507 scopus 로고    scopus 로고
    • NMDA receptors are expressed in lymphocytes activated both in vitro and in vivo
    • Mashkina A.P., Cizkova D., Vanicky I., Boldyrev A.A. NMDA receptors are expressed in lymphocytes activated both in vitro and in vivo. Cell. Mol. Neurobiol. 2010, 38:901-907.
    • (2010) Cell. Mol. Neurobiol. , vol.38 , pp. 901-907
    • Mashkina, A.P.1    Cizkova, D.2    Vanicky, I.3    Boldyrev, A.A.4
  • 35
    • 84872071680 scopus 로고    scopus 로고
    • Neurokinin-1 receptor directly mediates glioma cell migration by up-regulation of matrix metalloproteinase-2 (MMP-2) and membrane type 1-matrix metalloproteinase (MT1-MMP)
    • Mou L., Kang Y., Zhou Y., Zeng Q., Song H., Wang R. Neurokinin-1 receptor directly mediates glioma cell migration by up-regulation of matrix metalloproteinase-2 (MMP-2) and membrane type 1-matrix metalloproteinase (MT1-MMP). J. Biol. Chem. 2013, 288:306-318.
    • (2013) J. Biol. Chem. , vol.288 , pp. 306-318
    • Mou, L.1    Kang, Y.2    Zhou, Y.3    Zeng, Q.4    Song, H.5    Wang, R.6
  • 37
    • 7744223842 scopus 로고    scopus 로고
    • A two-hour window for hypothermic modulation of early events that impact delayed opening of the rat blood-brain barrier after ischemia
    • Preston E., Webster J. A two-hour window for hypothermic modulation of early events that impact delayed opening of the rat blood-brain barrier after ischemia. Acta Neuropathol. 2004, 108:406-412.
    • (2004) Acta Neuropathol. , vol.108 , pp. 406-412
    • Preston, E.1    Webster, J.2
  • 38
    • 67249146480 scopus 로고    scopus 로고
    • Occludin phosphorylation in regulation of epithelial tight junctions
    • Rao R. Occludin phosphorylation in regulation of epithelial tight junctions. Ann. N.Y. Acad. Sci. 2009, 1165:62-68.
    • (2009) Ann. N.Y. Acad. Sci. , vol.1165 , pp. 62-68
    • Rao, R.1
  • 40
    • 84871558287 scopus 로고    scopus 로고
    • Diversity in NMDA receptor composition: many regulators, many consequences
    • Sanz-Clemente A., Nicoll R.A., Roche K.W. Diversity in NMDA receptor composition: many regulators, many consequences. Neuroscientist 2013, 19:62-75.
    • (2013) Neuroscientist , vol.19 , pp. 62-75
    • Sanz-Clemente, A.1    Nicoll, R.A.2    Roche, K.W.3
  • 42
    • 3042786368 scopus 로고    scopus 로고
    • Molecular biology and ontogeny of glutamate receptors in the mammalian central nervous system
    • Simeone T.A., Sanchez R.M., Rho J.M. Molecular biology and ontogeny of glutamate receptors in the mammalian central nervous system. J. Child Neurol. 2004, 19:343-360.
    • (2004) J. Child Neurol. , vol.19 , pp. 343-360
    • Simeone, T.A.1    Sanchez, R.M.2    Rho, J.M.3
  • 43
    • 84878678457 scopus 로고    scopus 로고
    • Advances in the critical care management of ischemic stroke
    • Singh V., Edwards N.J. Advances in the critical care management of ischemic stroke. Stroke Res. Treat. 2013, 2013:510481.
    • (2013) Stroke Res. Treat. , vol.2013 , pp. 510481
    • Singh, V.1    Edwards, N.J.2
  • 44
    • 0344688189 scopus 로고    scopus 로고
    • Activation of ERK1/2 MAP kinase pathway induces tight junction disruption in human corneal epithelial cells
    • Wang Y., Zhang J., Yi X.J., Yu F.S. Activation of ERK1/2 MAP kinase pathway induces tight junction disruption in human corneal epithelial cells. Exp. Eye Res. 2004, 78:125-136.
    • (2004) Exp. Eye Res. , vol.78 , pp. 125-136
    • Wang, Y.1    Zhang, J.2    Yi, X.J.3    Yu, F.S.4
  • 46
    • 70449519075 scopus 로고    scopus 로고
    • Lipopolysaccharide triggers macrophage activation of inflammatory cytokine expression, chemotaxis, phagocytosis, and oxidative ability via a toll-like receptor 4-dependent pathway: validated by RNA interference
    • Wu T.T., Chen T.L., Chen R.M. Lipopolysaccharide triggers macrophage activation of inflammatory cytokine expression, chemotaxis, phagocytosis, and oxidative ability via a toll-like receptor 4-dependent pathway: validated by RNA interference. Toxicol. Lett. 2009, 191:195-202.
    • (2009) Toxicol. Lett. , vol.191 , pp. 195-202
    • Wu, T.T.1    Chen, T.L.2    Chen, R.M.3
  • 47
    • 79956370275 scopus 로고    scopus 로고
    • Lipopolysaccharide stimulates syntheses of toll-like receptor 2 and surfactant protein-A in human alveolar epithelial A549 cells through upregulating phosphorylation of MEK1 and ERK1/2 and sequential activation of NF-κB
    • Wu T.T., Chen T.L., Loon W.S., Tai Y.T., Cherng Y.G., Chen R.M. Lipopolysaccharide stimulates syntheses of toll-like receptor 2 and surfactant protein-A in human alveolar epithelial A549 cells through upregulating phosphorylation of MEK1 and ERK1/2 and sequential activation of NF-κB. Cytokine 2011, 55:40-47.
    • (2011) Cytokine , vol.55 , pp. 40-47
    • Wu, T.T.1    Chen, T.L.2    Loon, W.S.3    Tai, Y.T.4    Cherng, Y.G.5    Chen, R.M.6
  • 48
    • 0028107496 scopus 로고
    • Reduction of vasogenic edema and infarction by MK-801 in rats after temporary focal cerebral ischemia
    • Yang G., Chan P.H., Chen S.F., Babuna O.A., Simon R.P., Weinstein P.R. Reduction of vasogenic edema and infarction by MK-801 in rats after temporary focal cerebral ischemia. Neurosurgery 1994, 34:339-345.
    • (1994) Neurosurgery , vol.34 , pp. 339-345
    • Yang, G.1    Chan, P.H.2    Chen, S.F.3    Babuna, O.A.4    Simon, R.P.5    Weinstein, P.R.6
  • 49
    • 33947493391 scopus 로고    scopus 로고
    • Matrix metalloproteinase-mediated disruption of tight junction proteins in cerebral vessels is reversed by synthetic matrix metalloproteinase inhibitor in focal ischemia in rat
    • Yang Y., Estrada E.Y., Thompson J.F., Liu W., Rosenberg G.A. Matrix metalloproteinase-mediated disruption of tight junction proteins in cerebral vessels is reversed by synthetic matrix metalloproteinase inhibitor in focal ischemia in rat. J. Cereb. Blood Flow Metab. 2007, 27:697-709.
    • (2007) J. Cereb. Blood Flow Metab. , vol.27 , pp. 697-709
    • Yang, Y.1    Estrada, E.Y.2    Thompson, J.F.3    Liu, W.4    Rosenberg, G.A.5
  • 50
    • 0035853827 scopus 로고    scopus 로고
    • CAMP-dependent protein kinase induces cAMP-response element-binding protein phosphorylation via an intracellular calcium release/ERK-dependent pathway in striatal neurons
    • Zanassi P., Paolillo M., Feliciello A., Avvedimento E.V., Gallo V., Schinelli S. cAMP-dependent protein kinase induces cAMP-response element-binding protein phosphorylation via an intracellular calcium release/ERK-dependent pathway in striatal neurons. J. Biol. Chem. 2001, 276:11487-11495.
    • (2001) J. Biol. Chem. , vol.276 , pp. 11487-11495
    • Zanassi, P.1    Paolillo, M.2    Feliciello, A.3    Avvedimento, E.V.4    Gallo, V.5    Schinelli, S.6
  • 52
    • 34250754825 scopus 로고    scopus 로고
    • Haloperidol induces neurotoxicity by the NMDA receptor downstream signaling pathway, alternative from glutamate excitotoxicity
    • Zhuravliova E., Barbakadze T., Natsvlishvili N., Mikeladze D.G. Haloperidol induces neurotoxicity by the NMDA receptor downstream signaling pathway, alternative from glutamate excitotoxicity. Neurochem. Int. 2007, 50:976-982.
    • (2007) Neurochem. Int. , vol.50 , pp. 976-982
    • Zhuravliova, E.1    Barbakadze, T.2    Natsvlishvili, N.3    Mikeladze, D.G.4
  • 53
    • 33747890559 scopus 로고    scopus 로고
    • The brain as a target of inflammation: common pathways link inflammatory and neurodegenerative diseases
    • Zipp F., Aktas O. The brain as a target of inflammation: common pathways link inflammatory and neurodegenerative diseases. Trends Neurosci. 2006, 29:518-527.
    • (2006) Trends Neurosci. , vol.29 , pp. 518-527
    • Zipp, F.1    Aktas, O.2


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