메뉴 건너뛰기




Volumn 55, Issue 1, 2011, Pages 40-47

Lipopolysaccharide stimulates syntheses of toll-like receptor 2 and surfactant protein-A in human alveolar epithelial A549 cells through upregulating phosphorylation of MEK1 and ERK1/2 and sequential activation of NF-κB

Author keywords

Acute lung injury; Alveolar epithelial cells; LPS; SP A; TLR2

Indexed keywords

2 (2 AMINO 3 METHOXYPHENYL)CHROMONE; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; LIPOPOLYSACCHARIDE; MESSENGER RNA; MITOGEN ACTIVATED PROTEIN KINASE 1; MITOGEN ACTIVATED PROTEIN KINASE KINASE 1; MITOGEN ACTIVATED PROTEIN KINASE P38; OLIGONUCLEOTIDE; SURFACTANT PROTEIN A; TOLL LIKE RECEPTOR 2;

EID: 79956370275     PISSN: 10434666     EISSN: 10960023     Source Type: Journal    
DOI: 10.1016/j.cyto.2011.03.005     Document Type: Article
Times cited : (36)

References (33)
  • 1
    • 0034958947 scopus 로고    scopus 로고
    • Epidemiology of severe sepsis in the United States: analysis of incidence, outcome, and associated costs of care
    • Angus D.C., Linde-Zwirble W.T., Lidicker J., Clermont G., Carcillo J., Pinsky M.R. Epidemiology of severe sepsis in the United States: analysis of incidence, outcome, and associated costs of care. Crit Care Med 2001, 29:1303-1310.
    • (2001) Crit Care Med , vol.29 , pp. 1303-1310
    • Angus, D.C.1    Linde-Zwirble, W.T.2    Lidicker, J.3    Clermont, G.4    Carcillo, J.5    Pinsky, M.R.6
  • 2
    • 0026062620 scopus 로고
    • Gram-negative endotoxin: an extraordinary lipid with profound effects on eukaryotic signal transduction
    • Raetz C.R., Ulevitch R.J., Wright S.D., Sibley C.H., Ding A., Nathan C.F. Gram-negative endotoxin: an extraordinary lipid with profound effects on eukaryotic signal transduction. FASEB J 1991, 5:2652-2660.
    • (1991) FASEB J , vol.5 , pp. 2652-2660
    • Raetz, C.R.1    Ulevitch, R.J.2    Wright, S.D.3    Sibley, C.H.4    Ding, A.5    Nathan, C.F.6
  • 3
    • 0033860933 scopus 로고    scopus 로고
    • Role of transcription factors in fetal lung development and surfactant protein gene expression
    • Mendelson C.R. Role of transcription factors in fetal lung development and surfactant protein gene expression. Ann Rev Physiol 2000, 62:875-915.
    • (2000) Ann Rev Physiol , vol.62 , pp. 875-915
    • Mendelson, C.R.1
  • 4
    • 0034292361 scopus 로고    scopus 로고
    • Distinct effects of surfactant protein A or D deficiency during bacterial infection on the lung
    • LeVine A.M., Whitsett J.A., Gwozdz J.A., Richardson T.R., Fisher J.H., Burhans M.S., et al. Distinct effects of surfactant protein A or D deficiency during bacterial infection on the lung. J Immunol 2000, 165:3934-3940.
    • (2000) J Immunol , vol.165 , pp. 3934-3940
    • LeVine, A.M.1    Whitsett, J.A.2    Gwozdz, J.A.3    Richardson, T.R.4    Fisher, J.H.5    Burhans, M.S.6
  • 5
    • 0034999477 scopus 로고    scopus 로고
    • Regulation of surfactant secretion
    • Rooney S.A. Regulation of surfactant secretion. Comp Biochem Physiol 2001, 129:233-243.
    • (2001) Comp Biochem Physiol , vol.129 , pp. 233-243
    • Rooney, S.A.1
  • 6
    • 0035048532 scopus 로고    scopus 로고
    • Surfactant proteins A and D and pulmonary host defense
    • Crouch E., Wright J.R. Surfactant proteins A and D and pulmonary host defense. Ann Rev Physiol 2001, 63:521-554.
    • (2001) Ann Rev Physiol , vol.63 , pp. 521-554
    • Crouch, E.1    Wright, J.R.2
  • 7
    • 0035175493 scopus 로고    scopus 로고
    • Surfactant protein A (SP-A): the alveolus and beyond
    • Khubchandani K.R., Snyder J.M. Surfactant protein A (SP-A): the alveolus and beyond. FASEB J 2001, 15:59-69.
    • (2001) FASEB J , vol.15 , pp. 59-69
    • Khubchandani, K.R.1    Snyder, J.M.2
  • 8
    • 65649123377 scopus 로고    scopus 로고
    • Toll-like receptors and their role in hematologic malignancies
    • Wolska A., Lech-Maranda E., Robak T. Toll-like receptors and their role in hematologic malignancies. Curr Mol Med 2009, 9:324-335.
    • (2009) Curr Mol Med , vol.9 , pp. 324-335
    • Wolska, A.1    Lech-Maranda, E.2    Robak, T.3
  • 9
    • 0037297756 scopus 로고    scopus 로고
    • Toll-like receptor 2 is expressed by alveolar epithelial cells type II and macrophages in the human lung
    • Droemann D., Goldmann T., Branscheid D., Clark R., Dalhoff K., Zabel P., et al. Toll-like receptor 2 is expressed by alveolar epithelial cells type II and macrophages in the human lung. Histochem Cell Biol 2003, 119:103-108.
    • (2003) Histochem Cell Biol , vol.119 , pp. 103-108
    • Droemann, D.1    Goldmann, T.2    Branscheid, D.3    Clark, R.4    Dalhoff, K.5    Zabel, P.6
  • 10
    • 54549099000 scopus 로고    scopus 로고
    • CEACAM1 inhibits Toll-like receptor 2-triggered antibacterial responses of human pulmonary epithelial cells
    • Slevogt H., Zabel S., Opitz B., Hocke A., Eitel J., N'guessan P.D., et al. CEACAM1 inhibits Toll-like receptor 2-triggered antibacterial responses of human pulmonary epithelial cells. Nat Immunol 2008, 9:1270-1278.
    • (2008) Nat Immunol , vol.9 , pp. 1270-1278
    • Slevogt, H.1    Zabel, S.2    Opitz, B.3    Hocke, A.4    Eitel, J.5    N'guessan, P.D.6
  • 11
    • 1842477227 scopus 로고    scopus 로고
    • A toll-like receptor 2 ligand stimulates Th2 responses in vivo, via induction of extracellular signal-regulated kinase mitogen-activated protein kinase and c-Fos in dendritic cells
    • Dillon S., Agrawal A., van Dyke T., Landreth G., McCauley L., Koh A., et al. A toll-like receptor 2 ligand stimulates Th2 responses in vivo, via induction of extracellular signal-regulated kinase mitogen-activated protein kinase and c-Fos in dendritic cells. J Immunol 2004, 172:4733-4743.
    • (2004) J Immunol , vol.172 , pp. 4733-4743
    • Dillon, S.1    Agrawal, A.2    van Dyke, T.3    Landreth, G.4    McCauley, L.5    Koh, A.6
  • 12
    • 0034043956 scopus 로고    scopus 로고
    • Inhibition of lipopolysaccharide-induced signal transduction in endotoxin-tolerized mouse macrophages: dysregulation of cytokine, chemokine, and toll-like receptor 2 and 4 gene expression
    • Medvedev A.E., Kopydlowski K.M., Vogel S.N. Inhibition of lipopolysaccharide-induced signal transduction in endotoxin-tolerized mouse macrophages: dysregulation of cytokine, chemokine, and toll-like receptor 2 and 4 gene expression. J Immunol 2000, 64:5564-5574.
    • (2000) J Immunol , vol.64 , pp. 5564-5574
    • Medvedev, A.E.1    Kopydlowski, K.M.2    Vogel, S.N.3
  • 13
    • 0028204888 scopus 로고
    • Secretion of cytokines by rat alveolar epithelial cells: possible regulatory role for SP-A
    • Blau H., Riklis S., Kravtsov V., Kalina M. Secretion of cytokines by rat alveolar epithelial cells: possible regulatory role for SP-A. Am J Physiol 1994, 266:L148-L155.
    • (1994) Am J Physiol , vol.266
    • Blau, H.1    Riklis, S.2    Kravtsov, V.3    Kalina, M.4
  • 14
    • 70449528492 scopus 로고    scopus 로고
    • Molecular mechanisms of lipopolysaccharide-caused induction of surfactant protein-A gene expression in human alveolar epithelial A549 cells
    • Chuang C.Y., Chen T.L., Chen R.M. Molecular mechanisms of lipopolysaccharide-caused induction of surfactant protein-A gene expression in human alveolar epithelial A549 cells. Toxicol Lett 2009, 191:132-139.
    • (2009) Toxicol Lett , vol.191 , pp. 132-139
    • Chuang, C.Y.1    Chen, T.L.2    Chen, R.M.3
  • 15
    • 77951429357 scopus 로고    scopus 로고
    • Lipoteichoic acid-induced TNF-α and IL-6 gene expressions and oxidative stress production in macrophages are suppressed by ketamine through downregulating toll-like receptor 2-mediated activation of ERK1/2 and NFκB
    • Chuang H.C., Lin K.H., Tai Y.T., Chen J.T., Chen R.M. Lipoteichoic acid-induced TNF-α and IL-6 gene expressions and oxidative stress production in macrophages are suppressed by ketamine through downregulating toll-like receptor 2-mediated activation of ERK1/2 and NFκB. Shock 2010, 33:485-492.
    • (2010) Shock , vol.33 , pp. 485-492
    • Chuang, H.C.1    Lin, K.H.2    Tai, Y.T.3    Chen, J.T.4    Chen, R.M.5
  • 16
    • 72449145457 scopus 로고    scopus 로고
    • Runx2-mediated Bcl-2 gene expression contributes to nitric oxide protection against oxidative stress-induced osteoblast apoptosis
    • Ho W.P., Chan L.P., Hsieh M.S., Chen R.M. Runx2-mediated Bcl-2 gene expression contributes to nitric oxide protection against oxidative stress-induced osteoblast apoptosis. J Cell Biochem 2009, 108:1084-1093.
    • (2009) J Cell Biochem , vol.108 , pp. 1084-1093
    • Ho, W.P.1    Chan, L.P.2    Hsieh, M.S.3    Chen, R.M.4
  • 17
    • 70449519075 scopus 로고    scopus 로고
    • Lipopolysaccharide triggers macrophage activation of inflammatory cytokine expression, chemotaxis, phagocytosis, and oxidative ability via a toll-like receptor 4-dependent pathway: validated by RNA interference
    • Wu T.T., Chen T.L., Chen R.M. Lipopolysaccharide triggers macrophage activation of inflammatory cytokine expression, chemotaxis, phagocytosis, and oxidative ability via a toll-like receptor 4-dependent pathway: validated by RNA interference. Toxicol Lett 2009, 191:195-202.
    • (2009) Toxicol Lett , vol.191 , pp. 195-202
    • Wu, T.T.1    Chen, T.L.2    Chen, R.M.3
  • 18
    • 40849086200 scopus 로고    scopus 로고
    • Ketamine inhibits tumor necrosis factor-α and interleukin-6 gene expressions in lipopolysaccharide-stimulated macrophages through suppression of toll-like receptor 4-mediated c-Jun N-terminal kinase phosphorylation and activator protein-1 activation
    • Wu G.J., Chen T.L., Ueng Y.F., Chen R.M. Ketamine inhibits tumor necrosis factor-α and interleukin-6 gene expressions in lipopolysaccharide-stimulated macrophages through suppression of toll-like receptor 4-mediated c-Jun N-terminal kinase phosphorylation and activator protein-1 activation. Toxicol Appl Pharmacol 2008, 228:105-113.
    • (2008) Toxicol Appl Pharmacol , vol.228 , pp. 105-113
    • Wu, G.J.1    Chen, T.L.2    Ueng, Y.F.3    Chen, R.M.4
  • 19
    • 70249119956 scopus 로고    scopus 로고
    • Propofol inhibits lipoteichoic acid-induced iNOS gene expression in macrophages possibly through downregulation of toll-like receptor 2-mediated activation of Raf-MEK1/2-ERK1/2-IKK-NFκB
    • Chiu W.T., Lin Y.L., Chou C.W., Chen R.M. Propofol inhibits lipoteichoic acid-induced iNOS gene expression in macrophages possibly through downregulation of toll-like receptor 2-mediated activation of Raf-MEK1/2-ERK1/2-IKK-NFκB. Chem-Biol Interact 2009, 181:430-439.
    • (2009) Chem-Biol Interact , vol.181 , pp. 430-439
    • Chiu, W.T.1    Lin, Y.L.2    Chou, C.W.3    Chen, R.M.4
  • 20
    • 73849150748 scopus 로고    scopus 로고
    • Molecular mechanisms of propofol-involved suppression of nitric oxide biosynthesis and inducible nitric oxide synthase gene expression in lipopolysaccharide-stimulated macrophage-like RAW 264.7 cells
    • Lee C.J., Tai Y.T., Lin Y.L., Chen R.M. Molecular mechanisms of propofol-involved suppression of nitric oxide biosynthesis and inducible nitric oxide synthase gene expression in lipopolysaccharide-stimulated macrophage-like RAW 264.7 cells. Shock 2010, 33:93-100.
    • (2010) Shock , vol.33 , pp. 93-100
    • Lee, C.J.1    Tai, Y.T.2    Lin, Y.L.3    Chen, R.M.4
  • 21
    • 69549086363 scopus 로고    scopus 로고
    • Signal-transducing mechanisms of ketamine-caused inhibition of interleukin-1β gene expression in lipopolysaccharide-stimulated murine macrophage-like RAW 264.7 cells
    • Chen T.L., Chang C.C., Lin Y.L., Ueng Y.F., Chen R.M. Signal-transducing mechanisms of ketamine-caused inhibition of interleukin-1β gene expression in lipopolysaccharide-stimulated murine macrophage-like RAW 264.7 cells. Toxicol Appl Pharmacol 2009, 240:15-25.
    • (2009) Toxicol Appl Pharmacol , vol.240 , pp. 15-25
    • Chen, T.L.1    Chang, C.C.2    Lin, Y.L.3    Ueng, Y.F.4    Chen, R.M.5
  • 22
    • 0242668724 scopus 로고    scopus 로고
    • Propofol suppresses macrophage functions through modulating mitochondrial membrane potential and cellular adenosine triphosphate levels
    • Chen R.M., Wu C.H., Chang H.C., Wu G.J., Lin Y.L., Sheu J.R., et al. Propofol suppresses macrophage functions through modulating mitochondrial membrane potential and cellular adenosine triphosphate levels. Anesthesiology 2003, 98:1178-1185.
    • (2003) Anesthesiology , vol.98 , pp. 1178-1185
    • Chen, R.M.1    Wu, C.H.2    Chang, H.C.3    Wu, G.J.4    Lin, Y.L.5    Sheu, J.R.6
  • 23
    • 34548668886 scopus 로고    scopus 로고
    • Toll-like receptor 2 participates in the response to lung injury in a murine model of pulmonary contusion
    • Hoth J.J., Hudson W.P., Brownlee N.A., Yoza B.K., Hiltbold E.M., Meredith J.W., et al. Toll-like receptor 2 participates in the response to lung injury in a murine model of pulmonary contusion. Shock 2007, 28:447-452.
    • (2007) Shock , vol.28 , pp. 447-452
    • Hoth, J.J.1    Hudson, W.P.2    Brownlee, N.A.3    Yoza, B.K.4    Hiltbold, E.M.5    Meredith, J.W.6
  • 24
    • 0025258893 scopus 로고
    • Nuclear proto-oncogenes fos and jun
    • Ransone L.J., Verma I.M. Nuclear proto-oncogenes fos and jun. Ann Rev Cell Biol 1990, 6:539-557.
    • (1990) Ann Rev Cell Biol , vol.6 , pp. 539-557
    • Ransone, L.J.1    Verma, I.M.2
  • 25
    • 0036098552 scopus 로고    scopus 로고
    • AP-1 as a regulator of cell life and death
    • Shaulian E., Karin M. AP-1 as a regulator of cell life and death. Nat Cell Biol 2002, 4:E131-E136.
    • (2002) Nat Cell Biol , vol.4
    • Shaulian, E.1    Karin, M.2
  • 26
    • 67349279148 scopus 로고    scopus 로고
    • Propofol suppresses tumor necrosis factor-α biosynthesis in lipopolysaccharide-stimulated macrophages possibly through downregulation of nuclear factor-kappa B-mediated toll-like receptor 4 gene expression
    • Wu G.J., Chen T.L., Chang C.C., Chen R.M. Propofol suppresses tumor necrosis factor-α biosynthesis in lipopolysaccharide-stimulated macrophages possibly through downregulation of nuclear factor-kappa B-mediated toll-like receptor 4 gene expression. Chem-Biol Interact 2009, 180:465-471.
    • (2009) Chem-Biol Interact , vol.180 , pp. 465-471
    • Wu, G.J.1    Chen, T.L.2    Chang, C.C.3    Chen, R.M.4
  • 27
    • 0033553429 scopus 로고    scopus 로고
    • Very low-density lipoprotein activates nuclear factor-kappaB in endothelial cells
    • Dichtl W., Nilsson L., Goncalves I., Ares M.P., Banfi C., Calara F., et al. Very low-density lipoprotein activates nuclear factor-kappaB in endothelial cells. Circ Res 1999, 84:1085-1094.
    • (1999) Circ Res , vol.84 , pp. 1085-1094
    • Dichtl, W.1    Nilsson, L.2    Goncalves, I.3    Ares, M.P.4    Banfi, C.5    Calara, F.6
  • 28
    • 33846410348 scopus 로고    scopus 로고
    • Macrophage-secreted factors impair human adipogenesis: involvement of proinflammatory state in preadipocytes
    • Lacasa D., Taleb S., Keophiphath M., Miranville A., Clement K. Macrophage-secreted factors impair human adipogenesis: involvement of proinflammatory state in preadipocytes. Endocrinology 2007, 148:868-877.
    • (2007) Endocrinology , vol.148 , pp. 868-877
    • Lacasa, D.1    Taleb, S.2    Keophiphath, M.3    Miranville, A.4    Clement, K.5
  • 29
    • 0030271387 scopus 로고    scopus 로고
    • NF-κB: ten years after
    • Baeuerle P.A., Baltimore D. NF-κB: ten years after. Cell 1996, 87:13-20.
    • (1996) Cell , vol.87 , pp. 13-20
    • Baeuerle, P.A.1    Baltimore, D.2
  • 30
    • 0031906550 scopus 로고    scopus 로고
    • Signal transduction through NF-κB
    • May M.J., Ghosh S. Signal transduction through NF-κB. Immunol Today 1998, 19:80-88.
    • (1998) Immunol Today , vol.19 , pp. 80-88
    • May, M.J.1    Ghosh, S.2
  • 32
    • 34248544993 scopus 로고    scopus 로고
    • C-type lectin DC-SIGN modulates Toll-like receptor signaling via Raf-1 kinase-dependent acetylation of transcription factor NF-κB
    • Gringhuis S.I., den Dunnen J., Litjens M., van Het Hof B., van Kooyk Y., Geijtenbeek T.B. C-type lectin DC-SIGN modulates Toll-like receptor signaling via Raf-1 kinase-dependent acetylation of transcription factor NF-κB. Immunity 2007, 26:605-616.
    • (2007) Immunity , vol.26 , pp. 605-616
    • Gringhuis, S.I.1    den Dunnen, J.2    Litjens, M.3    van Het Hof, B.4    van Kooyk, Y.5    Geijtenbeek, T.B.6
  • 33
    • 33747792064 scopus 로고    scopus 로고
    • MAPK signalling: ERK5 versus ERK1/2
    • Nishimoto S., Nishida E. MAPK signalling: ERK5 versus ERK1/2. EMBO Rep 2006, 7:782-786.
    • (2006) EMBO Rep , vol.7 , pp. 782-786
    • Nishimoto, S.1    Nishida, E.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.