-
1
-
-
70350504453
-
The DNA-damage response in human biology and disease
-
Jackson SP, Bartek J. The DNA-damage response in human biology and disease. Nature 2009;461:1071-1078.
-
(2009)
Nature
, vol.461
, pp. 1071-1078
-
-
Jackson, S.P.1
Bartek, J.2
-
2
-
-
0036674617
-
Live or let die: The cell's response to p53
-
Vousden KH, Lu X. Live or let die: the cell's response to p53. Nat Rev Cancer 2002;8:594-604.
-
(2002)
Nat Rev Cancer
, vol.8
, pp. 594-604
-
-
Vousden, K.H.1
Lu, X.2
-
3
-
-
72949096551
-
Transcriptional control of the proliferation cluster by the tumor suppressor p53
-
Brosh R, Rotter V. Transcriptional control of the proliferation cluster by the tumor suppressor p53. Mol Biosyst 2010;1:17-29.
-
(2010)
Mol Biosyst
, vol.1
, pp. 17-29
-
-
Brosh, R.1
Rotter, V.2
-
4
-
-
77955858336
-
Posttranslational modification of p53: Cooperative integrators of function
-
Meek DW, Anderson CW. Posttranslational modification of p53: cooperative integrators of function. Cold Spring Harb Perspect Biol 2009;6:a000950.
-
(2009)
Cold Spring Harb Perspect Biol
, vol.6
, pp. a000950
-
-
Meek, D.W.1
Anderson, C.W.2
-
5
-
-
65349103899
-
Blinded by light: The growing complexity of p53
-
Vousden KH, Prives C. Blinded by light: the growing complexity of p53. Cell 2009;3:413-431.
-
(2009)
Cell
, vol.3
, pp. 413-431
-
-
Vousden, K.H.1
Prives, C.2
-
6
-
-
0034185612
-
Identification of a novel partner of RNA polymerase II subunit 11, Che-1, which interacts with and affects the growth suppression function of Rb
-
Fanciulli M, Bruno T, Di Padova M, De Angelis R, Iezzi S, Iacobini C et al. Identification of a novel partner of RNA polymerase II subunit 11, Che-1, which interacts with and affects the growth suppression function of Rb. FASEB J 2000;7:904-912.
-
(2000)
FASEB J
, vol.7
, pp. 904-912
-
-
Fanciulli, M.1
Bruno, T.2
Di Padova, M.3
De Angelis, R.4
Iezzi, S.5
Iacobini, C.6
-
7
-
-
0034669077
-
The murine gene, Traube, is essential for the growth of preimplantation embryos
-
Thomas T, Voss AK, Petrou P, Gruss P. The murine gene, Traube, is essential for the growth of preimplantation embryos. Dev Biol 2000;2:324-342.
-
(2000)
Dev Biol
, vol.2
, pp. 324-342
-
-
Thomas, T.1
Voss, A.K.2
Petrou, P.3
Gruss, P.4
-
8
-
-
19044373625
-
Che-1 affects cell growth by interfering with the recruitment of HDAC1 by Rb
-
Bruno T, De Angelis R, De Nicola F, Barbato C, Di Padova M, Corbi N et al. Che-1 affects cell growth by interfering with the recruitment of HDAC1 by Rb. Cancer Cell 2002;5:387-399.
-
(2002)
Cancer Cell
, vol.5
, pp. 387-399
-
-
Bruno, T.1
De Angelis, R.2
De Nicola, F.3
Barbato, C.4
Di Padova, M.5
Corbi, N.6
-
9
-
-
0344614655
-
AATF, a novel transcription factor that interacts with Dlk/ZIP kinase and interferes with apoptosis
-
Page G, Lödige I, Kögel D, Scheidtmann KH. AATF, a novel transcription factor that interacts with Dlk/ZIP kinase and interferes with apoptosis. FEBS Lett 1999;1-2:187-191.
-
(1999)
FEBS Lett
, vol.1-2
, pp. 187-191
-
-
Page, G.1
Lödige, I.2
Kögel, D.3
Scheidtmann, K.H.4
-
10
-
-
1042301394
-
AATF inhibits aberrant production of amyloid beta peptide 1-42 by interacting directly with Par-4
-
Guo Q, Xie J. AATF inhibits aberrant production of amyloid beta peptide 1-42 by interacting directly with Par-4. J Biol Chem 2004;6:4596-4603.
-
(2004)
J Biol Chem
, vol.6
, pp. 4596-4603
-
-
Guo, Q.1
Xie, J.2
-
11
-
-
39449136197
-
Che-1 activates XIAP expression in response to DNA damage
-
Bruno T, Iezzi S, De Nicola F, Di Padova M, Desantis A, Scarsella M et al. Che-1 activates XIAP expression in response to DNA damage. Cell Death Differ 2008;3:515-520.
-
(2008)
Cell Death Differ
, vol.3
, pp. 515-520
-
-
Bruno, T.1
Iezzi, S.2
De Nicola, F.3
Di Padova, M.4
Desantis, A.5
Scarsella, M.6
-
12
-
-
34547132819
-
The prolyl isomerase Pin1 affects Che-1 stability in response to apoptotic DNA damage
-
De Nicola F, Bruno T, Iezzi S, Di Padova M, Floridi A, Passananti C et al. The prolyl isomerase Pin1 affects Che-1 stability in response to apoptotic DNA damage. J Biol Chem 2007;27:19685-19691.
-
(2007)
J Biol Chem
, vol.27
, pp. 19685-19691
-
-
De Nicola, F.1
Bruno, T.2
Iezzi, S.3
Di Padova, M.4
Floridi, A.5
Passananti, C.6
-
13
-
-
34250802643
-
NRAGE associates with the anti-apoptotic factor Che-1 and regulates its degradation to induce cell death
-
Di Certo MG, Corbi N, Bruno T, Iezzi S, De Nicola F, Desantis A et al. NRAGE associates with the anti-apoptotic factor Che-1 and regulates its degradation to induce cell death. J Cell Sci 2007;11:1852-1858.
-
(2007)
J Cell Sci
, vol.11
, pp. 1852-1858
-
-
Di Certo, M.G.1
Corbi, N.2
Bruno, T.3
Iezzi, S.4
De Nicola, F.5
Desantis, A.6
-
14
-
-
33845187365
-
Che-1 phosphorylation by ATM/ATR and Chk2 kinases activates p53 transcription and the G2/M checkpoint
-
Bruno T, De Nicola F, Iezzi S, Lecis D, D'Angelo C, Di Padova M et al. Che-1 phosphorylation by ATM/ATR and Chk2 kinases activates p53 transcription and the G2/M checkpoint. Cancer Cell 2006;6:473-486.
-
(2006)
Cancer Cell
, vol.6
, pp. 473-486
-
-
Bruno, T.1
De Nicola, F.2
Iezzi, S.3
Lecis, D.4
D'Angelo, C.5
Di Padova, M.6
-
15
-
-
84867574821
-
AATF/Che-1 acts as a phosphorylation-dependent molecular modulator to repress p53-driven apoptosis
-
Höpker K, Hagmann H, Khurshid S, Chen S, Hasskamp P, Seeger-Nukpezah T et al. AATF/Che-1 acts as a phosphorylation-dependent molecular modulator to repress p53-driven apoptosis. EMBO J 2012;20:3961-3975.
-
(2012)
EMBO J
, vol.20
, pp. 3961-3975
-
-
Höpker, K.1
Hagmann, H.2
Khurshid, S.3
Chen, S.4
Hasskamp, P.5
Seeger-Nukpezah, T.6
-
16
-
-
18644384283
-
The prolyl isomerase Pin1 reveals a mechanism to control p53 functions after genotoxic insults
-
Zacchi P, Gostissa M, Uchida T, Salvagno C, Avolio F, Volinia S et al. The prolyl isomerase Pin1 reveals a mechanism to control p53 functions after genotoxic insults. Nature 2002;6909:853-857.
-
(2002)
Nature
, vol.6909
, pp. 853-857
-
-
Zacchi, P.1
Gostissa, M.2
Uchida, T.3
Salvagno, C.4
Avolio, F.5
Volinia, S.6
-
17
-
-
18644384688
-
The prolyl isomerase Pin1 is a regulator of p53 in genotoxic response
-
Zheng H, You H, Zhou XZ, Murray SA, Uchida T, Wulf G et al. The prolyl isomerase Pin1 is a regulator of p53 in genotoxic response. Nature 2002;6909:849-853.
-
(2002)
Nature
, vol.6909
, pp. 849-853
-
-
Zheng, H.1
You, H.2
Zhou, X.Z.3
Murray, S.A.4
Uchida, T.5
Wulf, G.6
-
18
-
-
0034664733
-
p53AIP1, a potential mediator of p53-dependent apoptosis, and its regulation by Ser-46-phosphorylated p53
-
Oda K, Arakawa H, Tanaka T, Matsuda K, Tanikawa C, Mori T et al. p53AIP1, a potential mediator of p53-dependent apoptosis, and its regulation by Ser-46-phosphorylated p53. Cell 2000;6:849-862.
-
(2000)
Cell
, vol.6
, pp. 849-862
-
-
Oda, K.1
Arakawa, H.2
Tanaka, T.3
Matsuda, K.4
Tanikawa, C.5
Mori, T.6
-
19
-
-
34948830225
-
The prolyl isomerase Pin1 orchestrates p53 acetylation and dissociation from the apoptosis inhibitor iASPP
-
Mantovani F, Tocco F, Girardini J, Smith P, Gasco M, Lu X et al. The prolyl isomerase Pin1 orchestrates p53 acetylation and dissociation from the apoptosis inhibitor iASPP. Nat Struct Mol Biol 2007;10:912-920.
-
(2007)
Nat Struct Mol Biol
, vol.10
, pp. 912-920
-
-
Mantovani, F.1
Tocco, F.2
Girardini, J.3
Smith, P.4
Gasco, M.5
Lu, X.6
-
20
-
-
0032473879
-
BRCA1 physically associates with p53 and stimulates its transcriptional activity
-
Zhang H, Somasundaram K, Peng Y, Tian H, Zhang H, Bi D et al. BRCA1 physically associates with p53 and stimulates its transcriptional activity. Oncogene 1998;13:1713-1721.
-
(1998)
Oncogene
, vol.13
, pp. 1713-1721
-
-
Zhang, H.1
Somasundaram, K.2
Peng, Y.3
Tian, H.4
Zhang, H.5
Bi, D.6
-
21
-
-
0036261733
-
BRCA1 directs a selective p53-dependent transcriptional response towards growth arrest and DNA repair targets
-
MacLachlan TK, Takimoto R, El-Deiry WS. BRCA1 directs a selective p53-dependent transcriptional response towards growth arrest and DNA repair targets. Mol Cell Biol 2002;12:4280-4292.
-
(2002)
Mol Cell Biol
, vol.12
, pp. 4280-4292
-
-
MacLachlan, T.K.1
Takimoto, R.2
El-Deiry, W.S.3
-
22
-
-
0038209424
-
BRCA1 shifts p53-mediated cellular outcomes towards irreversible growth arrest
-
Ongusaha PP, Ouchi T, Kim KT, Nytko E, Kwak JC, Duda RB et al. BRCA1 shifts p53-mediated cellular outcomes towards irreversible growth arrest. Oncogene 2003;24:3749-3758.
-
(2003)
Oncogene
, vol.24
, pp. 3749-3758
-
-
Ongusaha, P.P.1
Ouchi, T.2
Kim, K.T.3
Nytko, E.4
Kwak, J.C.5
Duda, R.B.6
-
23
-
-
17244367849
-
DNA damage response as a candidate anti-cancer barrier in early human tumorigenesis
-
Bartkova J, Horejsi Z, Koed K, Kramer A, Tort F, Zieger K et al. DNA damage response as a candidate anti-cancer barrier in early human tumorigenesis. Nature 2005;434:864-870.
-
(2005)
Nature
, vol.434
, pp. 864-870
-
-
Bartkova, J.1
Horejsi, Z.2
Koed, K.3
Kramer, A.4
Tort, F.5
Zieger, K.6
-
24
-
-
17244366865
-
Activation of the DNA damage checkpoint and genomic instability in human precancerous lesions
-
Gorgoulis VG, Vassiliou L-V F, Karakaidos P, Zacharatos P, Kotsinas A, Liloglou T et al. Activation of the DNA damage checkpoint and genomic instability in human precancerous lesions. Nature 2005;434:907-913.
-
(2005)
Nature
, vol.434
, pp. 907-913
-
-
Gorgoulis, V.G.1
Vassiliou, F.L.-V.2
Karakaidos, P.3
Zacharatos, P.4
Kotsinas, A.5
Liloglou, T.6
-
25
-
-
0036902410
-
53BP1 functions in an ATM-dependent checkpoint pathway that is constitutively activated in human cancer
-
DiTullio RA, Mochan TA, Venere M, Bartkova J, Schested M, Bartek J et al. 53BP1 functions in an ATM-dependent checkpoint pathway that is constitutively activated in human cancer. Nat Cell Biol 2002;4:998-1002.
-
(2002)
Nat Cell Biol
, vol.4
, pp. 998-1002
-
-
DiTullio, R.A.1
Mochan, T.A.2
Venere, M.3
Bartkova, J.4
Schested, M.5
Bartek, J.6
-
26
-
-
35848949304
-
DNA damage response as an anti-cancer barrier
-
Bartek J, Lukas J, Bartkova J. DNA damage response as an anti-cancer barrier. Cell Cycle 2007;6:2344-2347.
-
(2007)
Cell Cycle
, vol.6
, pp. 2344-2347
-
-
Bartek, J.1
Lukas, J.2
Bartkova, J.3
-
27
-
-
34548312368
-
Tip60 is a haplo-insufficient tumour suppressor required for an oncogene-induced DNA damage response
-
Gorrini C, Squatrito M, Luise C, Syed N, Perna D, Wark L et al. Tip60 is a haplo-insufficient tumour suppressor required for an oncogene-induced DNA damage response. Nature 2007;448:1063-1069.
-
(2007)
Nature
, vol.448
, pp. 1063-1069
-
-
Gorrini, C.1
Squatrito, M.2
Luise, C.3
Syed, N.4
Perna, D.5
Wark, L.6
-
28
-
-
0027319521
-
p53 is required for radiationinduced apoptosis in mouse thymocytes
-
Lowe SW, Schmitt EM, Smith SW, Osborne BA, Jacks T. p53 is required for radiationinduced apoptosis in mouse thymocytes. Nature 1993;362:847-849.
-
(1993)
Nature
, vol.362
, pp. 847-849
-
-
Lowe, S.W.1
Schmitt, E.M.2
Smith, S.W.3
Osborne, B.A.4
Jacks, T.5
-
29
-
-
0027258466
-
Thymocyte apoptosis induced by p53-dependent and independent pathways
-
Clarke AR, Purdie CA, Harrison DJ, Morris RG, Bird CC, Hooper ML et al. Thymocyte apoptosis induced by p53-dependent and independent pathways. Nature 1993;362:849-852.
-
(1993)
Nature
, vol.362
, pp. 849-852
-
-
Clarke, A.R.1
Purdie, C.A.2
Harrison, D.J.3
Morris, R.G.4
Bird, C.C.5
Hooper, M.L.6
-
30
-
-
33646757232
-
The complexity of p53 stabilization and activation
-
Lavin MF, Gueven N. The complexity of p53 stabilization and activation. Cell Death Diff 2006;13:941-950.
-
(2006)
Cell Death Diff
, vol.13
, pp. 941-950
-
-
Lavin, M.F.1
Gueven, N.2
-
31
-
-
84877574804
-
Another fork in the road-life or death decisions by the tumour suppressor p53
-
Carvajal LA, Manfredi JJ. Another fork in the road-life or death decisions by the tumour suppressor p53. EMBO Rep 2013;5:414-421.
-
(2013)
EMBO Rep
, vol.5
, pp. 414-421
-
-
Carvajal, L.A.1
Manfredi, J.J.2
-
32
-
-
33845668241
-
Tip60-dependent acetylation of p53 modulates the decision between cell-cycle arrest and apoptosis
-
Tang Y, Luo J, Zhang W, Gu W. Tip60-dependent acetylation of p53 modulates the decision between cell-cycle arrest and apoptosis. Mol Cell 2006;6:827-839.
-
(2006)
Mol Cell
, vol.6
, pp. 827-839
-
-
Tang, Y.1
Luo, J.2
Zhang, W.3
Gu, W.4
-
33
-
-
33845656738
-
Acetylation of the p53 DNA-binding domain regulates apoptosis induction
-
Sykes SM, Mellert HS, Holbert MA, Li K, Marmorstein R, Lane WS et al. Acetylation of the p53 DNA-binding domain regulates apoptosis induction. Mol Cell 2006;6:841-851.
-
(2006)
Mol Cell
, vol.6
, pp. 841-851
-
-
Sykes, S.M.1
Mellert, H.S.2
Holbert, M.A.3
Li, K.4
Marmorstein, R.5
Lane, W.S.6
-
34
-
-
53849146020
-
Model basis analysis of ChIP (MACS)
-
Zhang Y, Liu T, Meyer CA, Eeckhoute J, Johnson DS, Bernstein BE et al. Model basis analysis of ChIP (MACS). Genome Biol 2008;9:R137.
-
(2008)
Genome Biol
, vol.9
, pp. R137
-
-
Zhang, Y.1
Liu, T.2
Meyer, C.A.3
Eeckhoute, J.4
Johnson, D.S.5
Bernstein, B.E.6
-
35
-
-
77952567987
-
Simple combinations of lineage-determining transcription factors prime cis-regulatory elements required for macrophage and B cell identities
-
Heinz S, Benner C, Spann N, Bertolino E, Lin YC, Laslo P et al. Simple combinations of lineage-determining transcription factors prime cis-regulatory elements required for macrophage and B cell identities. Mol Cell 2010;38:576-589.
-
(2010)
Mol Cell
, vol.38
, pp. 576-589
-
-
Heinz, S.1
Benner, C.2
Spann, N.3
Bertolino, E.4
Lin, Y.C.5
Laslo, P.6
-
36
-
-
77952214662
-
GREAT improves functional interpretation of cis-regulatory regions
-
McLean YC, Bristor D, Hiller M, Clarke SL, Schaar BT, Lowe CB et al. GREAT improves functional interpretation of cis-regulatory regions. Nat Biotechnol 2010;28:495-501.
-
(2010)
Nat Biotechnol
, vol.28
, pp. 495-501
-
-
McLean, Y.C.1
Bristor, D.2
Hiller, M.3
Clarke, S.L.4
Schaar, B.T.5
Lowe, C.B.6
-
37
-
-
79960610118
-
REVIGO summarizes and visualizes long lists of Gene Ontology terms
-
Supek F, Bošnjak M, Škunca N, Šmuc T. REVIGO summarizes and visualizes long lists of Gene Ontology terms. PLoS ONE 2011;6:e21800.
-
(2011)
PLoS ONE
, vol.6
, pp. e21800
-
-
Supek, F.1
Bošnjak, M.2
Škunca, N.3
Šmuc, T.4
|