Che-1 activates XIAP expression in response to DNA damage

Cell Death and Differentiation

Volumn 15, Issue 3, 2008, Pages 515-520

  Bruno, T ^a   Iezzi, S ^a   De Nicola, F ^a   Di Padova, M ^b   Desantis, A ^b   Scarsella, M ^a   Di Certo, M G ^b,c   Leonetti, C ^a   Floridi, A ^a,b   Passananti, C ^a   Fanciulli, M ^a  

^a REGINA ELENA NATIONAL CANCER INSTITUTE   (Italy)

^b UNIVERSITY OF L'AQUILA   (Italy)

^c EUROPEAN BRAIN RESEARCH INSTITUTE   (Italy)

Author keywords

[No Author keywords available]

Indexed keywords

ANTINEOPLASTIC AGENT; BINDING PROTEIN; CHE 1 PROTEIN; CISPLATIN; DOXORUBICIN; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; SMALL INTERFERING RNA; UNCLASSIFIED DRUG; X LINKED INHIBITOR OF APOPTOSIS;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANTINEOPLASTIC ACTIVITY; ARTICLE; CANCER INHIBITION; CONTROLLED STUDY; DNA DAMAGE; DOWN REGULATION; DRUG CYTOTOXICITY; DRUG POTENTIATION; DRUG SENSITIVITY; DRUG TARGETING; GENE TARGETING; HUMAN; HUMAN CELL; IN VIVO STUDY; LARYNX CARCINOMA; MALE; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN PHOSPHORYLATION; SINGLE DRUG DOSE;

ANIMALS; APOPTOSIS; APOPTOSIS REGULATORY PROTEINS; CELL LINE, TUMOR; DNA DAMAGE; DRUG RESISTANCE, NEOPLASM; HUMANS; MALE; MICE; MICE, NUDE; NF-KAPPA B; NIH 3T3 CELLS; REPRESSOR PROTEINS; RNA INTERFERENCE; TRANS-ACTIVATION (GENETICS); TRANSCRIPTION FACTORS; UP-REGULATION; X-LINKED INHIBITOR OF APOPTOSIS PROTEIN;

EID: 39449136197     PISSN: 13509047     EISSN: 14765403     Source Type: Journal    
DOI: 10.1038/sj.cdd.4402284     Document Type: Article

References (22)

1. Jin Z, El-Deiry WS. Overview of cell death signaling pathways. Cancer Biol Ther 2005; 4: 139-163.
2. Salvesen GS, Dixit VM. Caspases: Intracellular signalling by proteolysis. Cell 1997; 91: 443-446.
3. Deveraux QL, Reed JC. IAP family proteins-suppressors of apoptosis. Genes Dev 1999; 13: 239-252.
4. Salvesen GS, Duckett CS. IAP proteins: Blocking the road to death's door. Nat Rev Mol Cell Biol 2002; 3: 401-410.
5. Eckelman BP, Salvesen GS, Scott FL. Human inhibitor of apoptosis proteins: Why XIAP is the black sheep of the family. EMBO Rep 2006; 7: 988-994.
6. LaCasse EC, Baird S, Korneluk RG, MacKenzie AE. The inhibitors of apoptosis (IAPs) and their emerging role in cancer. Oncogene 1998; 17: 3247-3259.
7. Schimmer AD, Dalili S, Batey RA, Riedl SJ. Targeting XIAP for the treatment of malignancy. Cell Death Differ 2006; 13: 179-188.
8. Fanciulli M, Bruno T, Di Padova M, De Angelis R, Iezzi S, Iacobini C et al Identification of a novel partner of RNA polymerase II subunit 11, Che-1, which interacts with and affects the growth suppression function of Rb. FASEB J 2000; 14: 904-912.
9. Thomas T, Voss AK, Petrou P, Gruss P. The murine gene, Traube, is essential for the growth of preimplantation embryos. Dev Biol 2000; 227: 324-342.
10. Lindfors K, Halttunen T, Huotari P, Nupponen N, Vihinen M, Visakorpi T et al Identification of novel transcription factor-like gene from human intestinal cells. Biochem Biophys Res Commun 2000; 276 660-666.
11. Page G, Lodige I, Kogel D, Scheidtmann KH. AATF, a novel transcription factor that interacts with Dlk/ZIP kinase and interferes with apoptosis. FEBS Letts 1999; 462: 187-191.
12. Burgdorf S, Leister P, Scheidtmann KH. TSG101 interacts with AATF and enhances AR-mediated transcription by promoting its mono-ubiquitination. J Biol Chem 2004; 279: 17524-17534.
13. Bruno T, De Angelis R, De Nicola F, Barbato C, Di Padova M, Corbi N et al Che-1 affects cell growth by interfering with the recruitment of HDAC1 by Rb. Cancer Cell 2002; 2: 387-399.
14. Guo Q, Xie J. AATF inhibits aberrant production of amyloid beta peptide 1-42 by interacting directly with Par-4. J Biol Chem 2004; 279 4596-4603.
15. De Nicola F, Bruno T, Iezzi S, Di Padova M, Floridi F, Passananti C et al The prolyl isomerase Pin1 affects Che-1 stability in response to apoptotic DNA damage. J Biol Chem 2007; 282: 19685-19691.
16. Di Certo MG, Corbi N, Bruno T, Iezzi S, De Nicola F, Desantis A et al NRAGE associates with the anti-apoptotic factor Che-1 and regulates its degradation to induce cell death. J Cell Sci 2007; 120: 1852-1858.
17. Di Padova M, Bruno T, De Nicola F, Iezzi S, D'Angelo C, Gallo R et al Che-1 arrests human colon carcinoma cell proliferation by displacing HDAC1 from the p21WAF1/CIP1 promoter. J Biol Chem 2003; 78: 36496-36504.
18. 2/M checkpoint. Cancer Cell 2006; 10 479-486.
19. Vousden KH, Lu X. Live or let die: The cell's response to p53. Nat Rev Cancer 2002; 2: 594-604.
20. Tang G, Minemoto Y, Dibling B, Purcell NH, Li Z, Karin M et al Inhibition of JNK activation through NF-kappa-B target genes. Nature 2001; 414: 313-317.
21. Geran RI, Greenberg NH, Macdonald MM, Shumacher AM, Abbott BJ. Protocols for screening chemical agents and natural products against animal tumors and other biological systems. Ed 3 Cancer Chemother Rep 1972; 3 1-88.
22. Schimmer AD. Inhibitor of apoptosis proteins: Translating basic knowledge into clinical practice. Cancer Res 2004; 64: 7183-7190.