메뉴 건너뛰기




Volumn 28, Issue 2, 2016, Pages 94-107

Necdin controls EGFR signaling linked to astrocyte differentiation in primary cortical progenitor cells

Author keywords

EGFR; ERK; Gliogenesis; MAGE family; Necdin

Indexed keywords

EPIDERMAL GROWTH FACTOR RECEPTOR; GROWTH FACTOR RECEPTOR BOUND PROTEIN 2; MITOGEN ACTIVATED PROTEIN KINASE; NECDIN; FIBROBLAST GROWTH FACTOR 2; NERVE PROTEIN; NUCLEAR PROTEIN;

EID: 84949309746     PISSN: 08986568     EISSN: 18733913     Source Type: Journal    
DOI: 10.1016/j.cellsig.2015.11.016     Document Type: Article
Times cited : (17)

References (72)
  • 1
    • 0026526516 scopus 로고
    • A multipotent EGF-responsive striatal embryonic progenitor cell produces neurons and astrocytes
    • Reynolds B.A., Tetzlaff W., Weiss S. A multipotent EGF-responsive striatal embryonic progenitor cell produces neurons and astrocytes. J. Neurosci. 1992, 12:4565-4574.
    • (1992) J. Neurosci. , vol.12 , pp. 4565-4574
    • Reynolds, B.A.1    Tetzlaff, W.2    Weiss, S.3
  • 2
    • 1642445643 scopus 로고    scopus 로고
    • Distinct neural stem cells proliferate in response to EGF and FGF in the developing mouse telencephalon
    • Tropepe V., Sibilia M., Ciruna B.G., Rossant J., Wagner E.F., van der Kooy D. Distinct neural stem cells proliferate in response to EGF and FGF in the developing mouse telencephalon. Dev. Biol. 1999, 208:166-188.
    • (1999) Dev. Biol. , vol.208 , pp. 166-188
    • Tropepe, V.1    Sibilia, M.2    Ciruna, B.G.3    Rossant, J.4    Wagner, E.F.5    van der Kooy, D.6
  • 3
    • 0037220756 scopus 로고    scopus 로고
    • Prospective cell sorting of embryonic rat neural stem cells and neuronal and glial progenitors reveals selective effects of basic fibroblast growth factor and epidermal growth factor on self-renewal and differentiation
    • Maric D., Maric I., Chang Y.H., Barker J.L. Prospective cell sorting of embryonic rat neural stem cells and neuronal and glial progenitors reveals selective effects of basic fibroblast growth factor and epidermal growth factor on self-renewal and differentiation. J. Neurosci. 2003, 23:240-251.
    • (2003) J. Neurosci. , vol.23 , pp. 240-251
    • Maric, D.1    Maric, I.2    Chang, Y.H.3    Barker, J.L.4
  • 4
    • 0029018239 scopus 로고
    • Cloned multipotential precursors from the mouse cerebrum require FGF-2, whereas glial restricted precursors are stimulated with either FGF-2 or EGF
    • Kilpatrick T.J., Bartlett P.F. Cloned multipotential precursors from the mouse cerebrum require FGF-2, whereas glial restricted precursors are stimulated with either FGF-2 or EGF. J. Neurosci. 1995, 15:3653-3661.
    • (1995) J. Neurosci. , vol.15 , pp. 3653-3661
    • Kilpatrick, T.J.1    Bartlett, P.F.2
  • 5
    • 0030869136 scopus 로고    scopus 로고
    • Response diversity and the timing of progenitor cell maturation are regulated by developmental changes in EGFR expression in the cortex
    • Burrows R.C., Wancio D., Levitt P., Lillien L. Response diversity and the timing of progenitor cell maturation are regulated by developmental changes in EGFR expression in the cortex. Neuron 1997, 19:251-267.
    • (1997) Neuron , vol.19 , pp. 251-267
    • Burrows, R.C.1    Wancio, D.2    Levitt, P.3    Lillien, L.4
  • 6
    • 0033636521 scopus 로고    scopus 로고
    • Timing of CNS cell generation: a programmed sequence of neuron and glial cell production from isolated murine cortical stem cells
    • Qian X., Shen Q., Goderie S.K., He W., Capela A., Davis A.A., Temple S. Timing of CNS cell generation: a programmed sequence of neuron and glial cell production from isolated murine cortical stem cells. Neuron 2000, 28:69-80.
    • (2000) Neuron , vol.28 , pp. 69-80
    • Qian, X.1    Shen, Q.2    Goderie, S.K.3    He, W.4    Capela, A.5    Davis, A.A.6    Temple, S.7
  • 7
    • 0033638139 scopus 로고    scopus 로고
    • BMP and FGF regulate the development of EGF-responsive neural progenitor cells
    • Lillien L., Raphael H. BMP and FGF regulate the development of EGF-responsive neural progenitor cells. Development 2000, 127:4993-5005.
    • (2000) Development , vol.127 , pp. 4993-5005
    • Lillien, L.1    Raphael, H.2
  • 8
    • 15444368299 scopus 로고    scopus 로고
    • Asymmetric distribution of EGFR receptor during mitosis generates diverse CNS progenitor cells
    • Sun Y., Goderie S.K., Temple S. Asymmetric distribution of EGFR receptor during mitosis generates diverse CNS progenitor cells. Neuron 2005, 45:873-886.
    • (2005) Neuron , vol.45 , pp. 873-886
    • Sun, Y.1    Goderie, S.K.2    Temple, S.3
  • 9
    • 0035499887 scopus 로고    scopus 로고
    • The development of neural stem cells
    • Temple S. The development of neural stem cells. Nature 2001, 414:112-117.
    • (2001) Nature , vol.414 , pp. 112-117
    • Temple, S.1
  • 10
    • 0030938231 scopus 로고    scopus 로고
    • Prenatal ontogeny of the epidermal growth factor receptor and its ligand, transforming growth factor alpha, in the rat brain
    • Kornblum H.I., Hussain R.J., Bronstein J.M., Gall C.M., Lee D.C., Seroogy K.B. Prenatal ontogeny of the epidermal growth factor receptor and its ligand, transforming growth factor alpha, in the rat brain. J. Comp. Neurol. 1997, 380:243-261.
    • (1997) J. Comp. Neurol. , vol.380 , pp. 243-261
    • Kornblum, H.I.1    Hussain, R.J.2    Bronstein, J.M.3    Gall, C.M.4    Lee, D.C.5    Seroogy, K.B.6
  • 12
    • 0032472938 scopus 로고    scopus 로고
    • A strain-independent postnatal neurodegeneration in mice lacking the EGF receptor
    • Sibilia M., Steinbach J.P., Stingl L., Aguzzi A., Wagner E.F. A strain-independent postnatal neurodegeneration in mice lacking the EGF receptor. EMBO J. 1998, 17:719-731.
    • (1998) EMBO J. , vol.17 , pp. 719-731
    • Sibilia, M.1    Steinbach, J.P.2    Stingl, L.3    Aguzzi, A.4    Wagner, E.F.5
  • 13
    • 0038673084 scopus 로고    scopus 로고
    • Epidermal growth factor receptors control competence to interpret leukemia inhibitory factor as an astrocyte inducer in developing cortex
    • Viti J., Feathers A., Phillips J., Lillien L. Epidermal growth factor receptors control competence to interpret leukemia inhibitory factor as an astrocyte inducer in developing cortex. J. Neurosci. 2003, 23:3385-3393.
    • (2003) J. Neurosci. , vol.23 , pp. 3385-3393
    • Viti, J.1    Feathers, A.2    Phillips, J.3    Lillien, L.4
  • 14
    • 0025871554 scopus 로고
    • A novel brain-specific mRNA encoding nuclear protein (necdin) expressed in neurally differentiated embryonal carcinoma cells
    • Maruyama K., Usami M., Aizawa T., Yoshikawa K. A novel brain-specific mRNA encoding nuclear protein (necdin) expressed in neurally differentiated embryonal carcinoma cells. Biochem. Biophys. Res. Commun. 1991, 178:291-296.
    • (1991) Biochem. Biophys. Res. Commun. , vol.178 , pp. 291-296
    • Maruyama, K.1    Usami, M.2    Aizawa, T.3    Yoshikawa, K.4
  • 15
    • 0030063033 scopus 로고    scopus 로고
    • Structure and expression of the mouse necdin gene. Identification of a postmitotic neuron-restrictive core promoter
    • Uetsuki T., Takagi K., Sugiura H., Yoshikawa K. Structure and expression of the mouse necdin gene. Identification of a postmitotic neuron-restrictive core promoter. J. Biol. Chem. 1996, 271:918-924.
    • (1996) J. Biol. Chem. , vol.271 , pp. 918-924
    • Uetsuki, T.1    Takagi, K.2    Sugiura, H.3    Yoshikawa, K.4
  • 16
    • 84879165939 scopus 로고    scopus 로고
    • Necdin controls proliferation and apoptosis of embryonic neural stem cells in an oxygen tension-dependent manner
    • Huang Z., Fujiwara K., Minamide R., Hasegawa K., Yoshikawa K. Necdin controls proliferation and apoptosis of embryonic neural stem cells in an oxygen tension-dependent manner. J. Neurosci. 2013, 33:10362-10373.
    • (2013) J. Neurosci. , vol.33 , pp. 10362-10373
    • Huang, Z.1    Fujiwara, K.2    Minamide, R.3    Hasegawa, K.4    Yoshikawa, K.5
  • 17
    • 84894275812 scopus 로고    scopus 로고
    • Antagonistic interplay between necdin and Bmi1 controls proliferation of neural precursor cells in the embryonic mouse neocortex
    • Minamide R., Fujiwara K., Hasegawa K., Yoshikawa K. Antagonistic interplay between necdin and Bmi1 controls proliferation of neural precursor cells in the embryonic mouse neocortex. PLoS One 2014, 9:e84460.
    • (2014) PLoS One , vol.9 , pp. e84460
    • Minamide, R.1    Fujiwara, K.2    Hasegawa, K.3    Yoshikawa, K.4
  • 18
    • 0031964697 scopus 로고    scopus 로고
    • Necdin, a postmitotic neuron-specific growth suppressor, interacts with viral transforming proteins and cellular transcription factor E2F1
    • Taniura H., Taniguchi N., Hara M., Yoshikawa K. Necdin, a postmitotic neuron-specific growth suppressor, interacts with viral transforming proteins and cellular transcription factor E2F1. J. Biol. Chem. 1998, 273:720-728.
    • (1998) J. Biol. Chem. , vol.273 , pp. 720-728
    • Taniura, H.1    Taniguchi, N.2    Hara, M.3    Yoshikawa, K.4
  • 19
    • 0033522919 scopus 로고    scopus 로고
    • Physical and functional interactions of neuronal growth suppressor necdin with p53
    • Taniura H., Matsumoto K., Yoshikawa K. Physical and functional interactions of neuronal growth suppressor necdin with p53. J. Biol. Chem. 1999, 274:16242-16248.
    • (1999) J. Biol. Chem. , vol.274 , pp. 16242-16248
    • Taniura, H.1    Matsumoto, K.2    Yoshikawa, K.3
  • 20
    • 33751081032 scopus 로고    scopus 로고
    • Necdin downregulates cdc2 expression to attenuate neuronal apoptosis
    • Kurita M., Kuwajima T., Nishimura I., Yoshikawa K. Necdin downregulates cdc2 expression to attenuate neuronal apoptosis. J. Neurosci. 2006, 26:12003-12013.
    • (2006) J. Neurosci. , vol.26 , pp. 12003-12013
    • Kurita, M.1    Kuwajima, T.2    Nishimura, I.3    Yoshikawa, K.4
  • 21
    • 52049096152 scopus 로고    scopus 로고
    • Necdin regulates p53 acetylation via Sirtuin1 to modulate DNA damage response in cortical neurons
    • Hasegawa K., Yoshikawa K. Necdin regulates p53 acetylation via Sirtuin1 to modulate DNA damage response in cortical neurons. J. Neurosci. 2008, 28:8772-8784.
    • (2008) J. Neurosci. , vol.28 , pp. 8772-8784
    • Hasegawa, K.1    Yoshikawa, K.2
  • 24
    • 0033798523 scopus 로고    scopus 로고
    • Cellular and subcellular localization of necdin in fetal and adult mouse brain
    • Niinobe M., Koyama K., Yoshikawa K. Cellular and subcellular localization of necdin in fetal and adult mouse brain. Dev. Neurosci. 2000, 22:310-319.
    • (2000) Dev. Neurosci. , vol.22 , pp. 310-319
    • Niinobe, M.1    Koyama, K.2    Yoshikawa, K.3
  • 25
    • 78650219793 scopus 로고    scopus 로고
    • Neural stem cell-like gene expression in a mouse ependymoma cell line transformed by human BK polyomavirus
    • Aizawa T., Hasegawa K., Ohkumo T., Haga S., Ikeda K., Yoshikawa K. Neural stem cell-like gene expression in a mouse ependymoma cell line transformed by human BK polyomavirus. Cancer Sci. 2011, 102:122-129.
    • (2011) Cancer Sci. , vol.102 , pp. 122-129
    • Aizawa, T.1    Hasegawa, K.2    Ohkumo, T.3    Haga, S.4    Ikeda, K.5    Yoshikawa, K.6
  • 26
    • 20444395224 scopus 로고    scopus 로고
    • Functional domains of necdin for protein-protein interaction, nuclear matrix targeting, and cell growth suppression
    • Taniura H., Kobayashi M., Yoshikawa K. Functional domains of necdin for protein-protein interaction, nuclear matrix targeting, and cell growth suppression. J. Cell. Biochem. 2005, 94:804-815.
    • (2005) J. Cell. Biochem. , vol.94 , pp. 804-815
    • Taniura, H.1    Kobayashi, M.2    Yoshikawa, K.3
  • 27
    • 84902590389 scopus 로고    scopus 로고
    • Necdin promotes ubiquitin-dependent degradation of PIAS1 SUMO E3 ligase
    • Gur I., Fujiwara K., Hasegawa K., Yoshikawa K. Necdin promotes ubiquitin-dependent degradation of PIAS1 SUMO E3 ligase. PLoS One 2014, 9:e99503.
    • (2014) PLoS One , vol.9 , pp. e99503
    • Gur, I.1    Fujiwara, K.2    Hasegawa, K.3    Yoshikawa, K.4
  • 28
    • 0030448423 scopus 로고    scopus 로고
    • Single factors direct the differentiation of stem cells from the fetal and adult central nervous system
    • Johe K.K., Hazel T.G., Muller T., Dugich-Djordjevic M.M., McKay R.D. Single factors direct the differentiation of stem cells from the fetal and adult central nervous system. Genes Dev. 1996, 10:3129-3140.
    • (1996) Genes Dev. , vol.10 , pp. 3129-3140
    • Johe, K.K.1    Hazel, T.G.2    Muller, T.3    Dugich-Djordjevic, M.M.4    McKay, R.D.5
  • 31
    • 0035821609 scopus 로고    scopus 로고
    • Astrocyte differentiation of fetal neuroepithelial cells involving cardiotrophin-1-induced activation of STAT3
    • Ochiai W., Yanagisawa M., Takizawa T., Nakashima K., Taga T. Astrocyte differentiation of fetal neuroepithelial cells involving cardiotrophin-1-induced activation of STAT3. Cytokine 2001, 14:264-271.
    • (2001) Cytokine , vol.14 , pp. 264-271
    • Ochiai, W.1    Yanagisawa, M.2    Takizawa, T.3    Nakashima, K.4    Taga, T.5
  • 33
    • 33846218204 scopus 로고    scopus 로고
    • Epidermal growth factor receptor-mediated signal transduction in the development and therapy of gliomas
    • Nicholas M.K., Lukas R.V., Jafri N.F., Faoro L., Salgia R. Epidermal growth factor receptor-mediated signal transduction in the development and therapy of gliomas. Clin. Cancer Res. 2006, 12:7261-7270.
    • (2006) Clin. Cancer Res. , vol.12 , pp. 7261-7270
    • Nicholas, M.K.1    Lukas, R.V.2    Jafri, N.F.3    Faoro, L.4    Salgia, R.5
  • 34
    • 0036675901 scopus 로고    scopus 로고
    • The molecular and genetic basis of neurological tumours
    • Zhu Y., Parada L.F. The molecular and genetic basis of neurological tumours. Nat. Rev. Cancer 2002, 2:616-626.
    • (2002) Nat. Rev. Cancer , vol.2 , pp. 616-626
    • Zhu, Y.1    Parada, L.F.2
  • 35
    • 20444363057 scopus 로고    scopus 로고
    • Neurofibromin regulates neural stem cell proliferation, survival, and astroglial differentiation in vitro and in vivo
    • Dasgupta B., Gutmann D.H. Neurofibromin regulates neural stem cell proliferation, survival, and astroglial differentiation in vitro and in vivo. J. Neurosci. 2005, 25:5584-5594.
    • (2005) J. Neurosci. , vol.25 , pp. 5584-5594
    • Dasgupta, B.1    Gutmann, D.H.2
  • 37
    • 84865229731 scopus 로고    scopus 로고
    • ERK inhibition rescues defects in fate specification of Nf1-deficient neural progenitors and brain abnormalities
    • Wang Y., Kim E., Wang X., Novitch B.G., Yoshikawa K., Chang L.S., Zhu Y. ERK inhibition rescues defects in fate specification of Nf1-deficient neural progenitors and brain abnormalities. Cell 2012, 150:816-830.
    • (2012) Cell , vol.150 , pp. 816-830
    • Wang, Y.1    Kim, E.2    Wang, X.3    Novitch, B.G.4    Yoshikawa, K.5    Chang, L.S.6    Zhu, Y.7
  • 41
    • 33745002702 scopus 로고    scopus 로고
    • An allosteric mechanism for activation of the kinase domain of epidermal growth factor receptor
    • Zhang X., Gureasko J., Shen K., Cole P.A., Kuriyan J. An allosteric mechanism for activation of the kinase domain of epidermal growth factor receptor. Cell 2006, 125:1137-1149.
    • (2006) Cell , vol.125 , pp. 1137-1149
    • Zhang, X.1    Gureasko, J.2    Shen, K.3    Cole, P.A.4    Kuriyan, J.5
  • 43
    • 36749011864 scopus 로고    scopus 로고
    • Inhibition of the EGF receptor by binding of MIG6 to an activating kinase domain interface
    • Zhang X., Pickin K.A., Bose R., Jura N., Cole P.A., Kuriyan J. Inhibition of the EGF receptor by binding of MIG6 to an activating kinase domain interface. Nature 2007, 450:741-744.
    • (2007) Nature , vol.450 , pp. 741-744
    • Zhang, X.1    Pickin, K.A.2    Bose, R.3    Jura, N.4    Cole, P.A.5    Kuriyan, J.6
  • 44
    • 79958154460 scopus 로고    scopus 로고
    • Regulation of epidermal growth factor receptor signalling by inducible feedback inhibitors
    • Segatto O., Anastasi S., Alema S. Regulation of epidermal growth factor receptor signalling by inducible feedback inhibitors. J. Cell Sci. 2011, 124:1785-1793.
    • (2011) J. Cell Sci. , vol.124 , pp. 1785-1793
    • Segatto, O.1    Anastasi, S.2    Alema, S.3
  • 45
    • 37149025094 scopus 로고    scopus 로고
    • The evolutionarily conserved EBR module of RALT/MIG6 mediates suppression of the EGFR catalytic activity
    • Anastasi S., Baietti M.F., Frosi Y., Alema S., Segatto O. The evolutionarily conserved EBR module of RALT/MIG6 mediates suppression of the EGFR catalytic activity. Oncogene 2007, 26:7833-7846.
    • (2007) Oncogene , vol.26 , pp. 7833-7846
    • Anastasi, S.1    Baietti, M.F.2    Frosi, Y.3    Alema, S.4    Segatto, O.5
  • 47
    • 10344239413 scopus 로고    scopus 로고
    • Gefitinib-a novel targeted approach to treating cancer
    • Herbst R.S., Fukuoka M., Baselga J. Gefitinib-a novel targeted approach to treating cancer. Nat. Rev. Cancer 2004, 4:956-965.
    • (2004) Nat. Rev. Cancer , vol.4 , pp. 956-965
    • Herbst, R.S.1    Fukuoka, M.2    Baselga, J.3
  • 49
    • 0035879005 scopus 로고    scopus 로고
    • An overview of the MAGE gene family with the identification of all human members of the family
    • Chomez P., De Backer O., Bertrand M., De Plaen E., Boon T., Lucas S. An overview of the MAGE gene family with the identification of all human members of the family. Cancer Res. 2001, 61:5544-5551.
    • (2001) Cancer Res. , vol.61 , pp. 5544-5551
    • Chomez, P.1    De Backer, O.2    Bertrand, M.3    De Plaen, E.4    Boon, T.5    Lucas, S.6
  • 50
    • 0026729978 scopus 로고
    • Expression of necdin, an embryonal carcinoma-derived nuclear protein, in developing mouse brain
    • Aizawa T., Maruyama K., Kondo H., Yoshikawa K. Expression of necdin, an embryonal carcinoma-derived nuclear protein, in developing mouse brain. Brain Res. Dev. Brain Res. 1992, 68:265-274.
    • (1992) Brain Res. Dev. Brain Res. , vol.68 , pp. 265-274
    • Aizawa, T.1    Maruyama, K.2    Kondo, H.3    Yoshikawa, K.4
  • 51
    • 0036829043 scopus 로고    scopus 로고
    • Ectopic expression of necdin induces differentiation of mouse neuroblastoma cells
    • Kobayashi M., Taniura H., Yoshikawa K. Ectopic expression of necdin induces differentiation of mouse neuroblastoma cells. J. Biol. Chem. 2002, 277:42128-42135.
    • (2002) J. Biol. Chem. , vol.277 , pp. 42128-42135
    • Kobayashi, M.1    Taniura, H.2    Yoshikawa, K.3
  • 53
    • 84924536829 scopus 로고    scopus 로고
    • Evaluation of melanoma antigen (MAGE) gene expression in human cancers using The Cancer Genome Atlas
    • Li X., Hughes S.C., Wevrick R. Evaluation of melanoma antigen (MAGE) gene expression in human cancers using The Cancer Genome Atlas. Cancer Genet. 2015, 208:25-34.
    • (2015) Cancer Genet. , vol.208 , pp. 25-34
    • Li, X.1    Hughes, S.C.2    Wevrick, R.3
  • 55
    • 0032525844 scopus 로고    scopus 로고
    • The human chromosomal gene for necdin, a neuronal growth suppressor, in the Prader-Willi syndrome deletion region
    • Nakada Y., Taniura H., Uetsuki T., Inazawa J., Yoshikawa K. The human chromosomal gene for necdin, a neuronal growth suppressor, in the Prader-Willi syndrome deletion region. Gene 1998, 213:65-72.
    • (1998) Gene , vol.213 , pp. 65-72
    • Nakada, Y.1    Taniura, H.2    Uetsuki, T.3    Inazawa, J.4    Yoshikawa, K.5
  • 57
    • 0030773594 scopus 로고    scopus 로고
    • The necdin gene is deleted in Prader-Willi syndrome and is imprinted in human and mouse
    • MacDonald H.R., Wevrick R. The necdin gene is deleted in Prader-Willi syndrome and is imprinted in human and mouse. Hum. Mol. Genet. 1997, 6:1873-1878.
    • (1997) Hum. Mol. Genet. , vol.6 , pp. 1873-1878
    • MacDonald, H.R.1    Wevrick, R.2
  • 58
    • 0345062183 scopus 로고    scopus 로고
    • Disruption of the mouse necdin gene results in early post-natal lethality
    • Gerard M., Hernandez L., Wevrick R., Stewart C.L. Disruption of the mouse necdin gene results in early post-natal lethality. Nat. Genet. 1999, 23:199-202.
    • (1999) Nat. Genet. , vol.23 , pp. 199-202
    • Gerard, M.1    Hernandez, L.2    Wevrick, R.3    Stewart, C.L.4
  • 59
    • 0034642301 scopus 로고    scopus 로고
    • Disruption of the mouse necdin gene results in hypothalamic and behavioral alterations reminiscent of the human Prader-Willi syndrome
    • Muscatelli F., Abrous D.N., Massacrier A., Boccaccio I., Le Moal M., Cau P., Cremer H. Disruption of the mouse necdin gene results in hypothalamic and behavioral alterations reminiscent of the human Prader-Willi syndrome. Hum. Mol. Genet. 2000, 9:3101-3110.
    • (2000) Hum. Mol. Genet. , vol.9 , pp. 3101-3110
    • Muscatelli, F.1    Abrous, D.N.2    Massacrier, A.3    Boccaccio, I.4    Le Moal, M.5    Cau, P.6    Cremer, H.7
  • 62
    • 0037335439 scopus 로고    scopus 로고
    • Absence of Ndn, encoding the Prader-Willi syndrome-deleted gene necdin, results in congenital deficiency of central respiratory drive in neonatal mice
    • Ren J., Lee S., Pagliardini S., Gerard M., Stewart C.L., Greer J.J., Wevrick R. Absence of Ndn, encoding the Prader-Willi syndrome-deleted gene necdin, results in congenital deficiency of central respiratory drive in neonatal mice. J. Neurosci. 2003, 23:1569-1573.
    • (2003) J. Neurosci. , vol.23 , pp. 1569-1573
    • Ren, J.1    Lee, S.2    Pagliardini, S.3    Gerard, M.4    Stewart, C.L.5    Greer, J.J.6    Wevrick, R.7
  • 63
    • 33744996959 scopus 로고    scopus 로고
    • Necdin promotes GABAergic neuron differentiation in cooperation with Dlx homeodomain proteins
    • Kuwajima T., Nishimura I., Yoshikawa K. Necdin promotes GABAergic neuron differentiation in cooperation with Dlx homeodomain proteins. J. Neurosci. 2006, 26:5383-5392.
    • (2006) J. Neurosci. , vol.26 , pp. 5383-5392
    • Kuwajima, T.1    Nishimura, I.2    Yoshikawa, K.3
  • 64
    • 77949342623 scopus 로고    scopus 로고
    • Necdin promotes tangential migration of neocortical interneurons from basal forebrain
    • Kuwajima T., Hasegawa K., Yoshikawa K. Necdin promotes tangential migration of neocortical interneurons from basal forebrain. J. Neurosci. 2010, 30:3709-3714.
    • (2010) J. Neurosci. , vol.30 , pp. 3709-3714
    • Kuwajima, T.1    Hasegawa, K.2    Yoshikawa, K.3
  • 66
    • 46949100270 scopus 로고    scopus 로고
    • Loss of the Prader-Willi syndrome protein necdin causes defective migration, axonal outgrowth, and survival of embryonic sympathetic neurons
    • Tennese A.A., Gee C.B., Wevrick R. Loss of the Prader-Willi syndrome protein necdin causes defective migration, axonal outgrowth, and survival of embryonic sympathetic neurons. Dev. Dyn. 2008, 237:1935-1943.
    • (2008) Dev. Dyn. , vol.237 , pp. 1935-1943
    • Tennese, A.A.1    Gee, C.B.2    Wevrick, R.3
  • 67
    • 58049209787 scopus 로고    scopus 로고
    • Necdin, a Prader-Willi syndrome candidate gene, regulates gonadotropin-releasing hormone neurons during development
    • Miller N.L., Wevrick R., Mellon P.L. Necdin, a Prader-Willi syndrome candidate gene, regulates gonadotropin-releasing hormone neurons during development. Hum. Mol. Genet. 2009, 18:248-260.
    • (2009) Hum. Mol. Genet. , vol.18 , pp. 248-260
    • Miller, N.L.1    Wevrick, R.2    Mellon, P.L.3
  • 68
    • 77957363111 scopus 로고    scopus 로고
    • Loss of necdin impairs myosin activation and delays cell polarization
    • Bush J.R., Wevrick R. Loss of necdin impairs myosin activation and delays cell polarization. Genesis 2010, 48:540-553.
    • (2010) Genesis , vol.48 , pp. 540-553
    • Bush, J.R.1    Wevrick, R.2
  • 71
    • 84857797436 scopus 로고    scopus 로고
    • Loss of the Prader-Willi obesity syndrome protein necdin promotes adipogenesis
    • Bush J.R., Wevrick R. Loss of the Prader-Willi obesity syndrome protein necdin promotes adipogenesis. Gene 2012, 497:45-51.
    • (2012) Gene , vol.497 , pp. 45-51
    • Bush, J.R.1    Wevrick, R.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.