ROS activates JNK-mediated autophagy to counteract apoptosis in mouse mesenchymal stem cells in vitro

Acta Pharmacologica Sinica

Volumn 36, Issue 12, 2015, Pages 1473-1479

  Liu, Guan Yu ^a   Jiang, Xiao Xue ^a   Zhu, Xin ^a   He, Wei Yang ^a   Kuang, You Lin ^a   Ren, Ke ^a   Lin, Yong ^b   Gou, Xin ^a  

^a THE FIRST AFFILIATED HOSPITAL OF CHONGQING MEDICAL UNIVERSITY   (China)

^b LOVELACE RESPIRATORY RESEARCH INSTITUTE   (United States)

Author keywords

3 methyladenine; apoptosis; autophagy; chloroquine; diabetes mellitus; erectile dysfunction; mesenchymal stem cell; ROS; SP600125

Indexed keywords

3 METHYLADENINE; ANTHRA[1,9 CD]PYRAZOL 6(2H) ONE; CHLOROQUINE; HYDROGEN PEROXIDE; PROTEIN BCL 2; REACTIVE OXYGEN METABOLITE; STRESS ACTIVATED PROTEIN KINASE; MITOGEN ACTIVATED PROTEIN KINASE KINASE 4;

ANIMAL CELL; APOPTOSIS; ARTICLE; AUTOPHAGOSOME; AUTOPHAGY; CELL DEATH; CELL SURVIVAL; CELL VIABILITY; CONTROLLED STUDY; FLOW CYTOMETRY; IN VITRO STUDY; MESENCHYMAL STEM CELL; MOUSE; MTT ASSAY; NONHUMAN; PROTEIN DEGRADATION; TRANSMISSION ELECTRON MICROSCOPY; WESTERN BLOTTING; ANIMAL; CELL LINE; CYTOLOGY; ENZYME ACTIVATION; ERECTILE DYSFUNCTION; MALE; MESENCHYMAL STEM CELL TRANSPLANTATION; MESENCHYMAL STROMA CELL; METABOLISM; OXIDATIVE STRESS;

ANIMALS; APOPTOSIS; AUTOPHAGY; CELL LINE; CELL SURVIVAL; ENZYME ACTIVATION; ERECTILE DYSFUNCTION; HYDROGEN PEROXIDE; MALE; MAP KINASE KINASE 4; MESENCHYMAL STEM CELL TRANSPLANTATION; MESENCHYMAL STROMAL CELLS; MICE; OXIDATIVE STRESS; REACTIVE OXYGEN SPECIES;

EID: 84949195095     PISSN: 16714083     EISSN: 17457254     Source Type: Journal    
DOI: 10.1038/aps.2015.101     Document Type: Article

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