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Volumn 9781461462965, Issue , 2013, Pages 375-400

Applying the AIM concept in support of developing improved in vitro-in vivo relationships for OIPs

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EID: 84949178643     PISSN: None     EISSN: None     Source Type: Book    
DOI: 10.1007/978-1-4614-6296-5_12     Document Type: Chapter
Times cited : (3)

References (66)
  • 1
    • 38049138950 scopus 로고    scopus 로고
    • In vitro and in vivo aspects of cascade impactor tests and inhaler performance: A review
    • Accessed 23 Jan 2012
    • Mitchell JP, Newman SP, Chan H-K (2007) In vitro and in vivo aspects of cascade impactor tests and inhaler performance: a review. AAPS PharmSciTech 8(4): article 24 at: http://www.aapspharmscitech.org/view.asp?art=pt0804110. Accessed 23 Jan 2012
    • (2007) AAPS PharmSciTech , vol.8 , Issue.4
    • Mitchell, J.P.1    Newman, S.P.2    Chan, H.-K.3
  • 2
    • 45949112470 scopus 로고    scopus 로고
    • In vitro/in vivo comparisons in pulmonary drug delivery
    • Newman SP, Chan H-K (2008) In vitro/in vivo comparisons in pulmonary drug delivery. J Aerosol Med 21(1):1-8
    • (2008) J Aerosol Med , vol.21 , Issue.1 , pp. 1-8
    • Newman, S.P.1    Chan, H.-K.2
  • 3
    • 0025345250 scopus 로고
    • Aerosols for delivery of therapeutic and diagnostic agents to the respiratory tract
    • Gonda I (1990) Aerosols for delivery of therapeutic and diagnostic agents to the respiratory tract. Crit Rev Ther Drug Carrier Syst 7:273-313
    • (1990) Crit Rev Ther Drug Carrier Syst , vol.7 , pp. 273-313
    • Gonda, I.1
  • 4
    • 6044257275 scopus 로고    scopus 로고
    • Clinical pharmacokinetics and pharmacodynamics of inhaled insulin
    • Patton JS, Bukar JG, Eldon MA (2004) Clinical pharmacokinetics and pharmacodynamics of inhaled insulin. Clin Pharmacokinet 43(12):781-801
    • (2004) Clin Pharmacokinet , vol.43 , Issue.12 , pp. 781-801
    • Patton, J.S.1    Bukar, J.G.2    Eldon, M.A.3
  • 6
    • 30444452988 scopus 로고    scopus 로고
    • Regional lung deposition and bronchodilator response as a Function of ?2-agonist particle size
    • Usmani OS, Biddiscombe MF, Barnes PJ (2005) Regional lung deposition and bronchodilator response as a Function of ?2-agonist particle size. Am J Respir Crit Care Med 172(12): 1497-1504
    • (2005) Am J Respir Crit Care Med , vol.172 , Issue.12 , pp. 1497-1504
    • Usmani, O.S.1    Biddiscombe, M.F.2    Barnes, P.J.3
  • 7
    • 29844443399 scopus 로고    scopus 로고
    • Analysis of cascade impactor mass distributions
    • Dunbar C, Mitchell JP (2005) Analysis of cascade impactor mass distributions. J Aerosol Med 18(4):439-451
    • (2005) J Aerosol Med , vol.18 , Issue.4 , pp. 439-451
    • Dunbar, C.1    Mitchell, J.P.2
  • 8
    • 47249149520 scopus 로고
    • The inhalation of aerosols
    • Vincent JH (ed) Pergamon Press, Oxford
    • Vincent JH (1995) The inhalation of aerosols. In: Vincent JH (ed) Aerosol science for industrial hygienists. Pergamon Press, Oxford, pp 136-155
    • (1995) Aerosol Science for Industrial Hygienists , pp. 136-155
    • Vincent, J.H.1
  • 9
    • 7144235822 scopus 로고    scopus 로고
    • Impact of oropharyngeal deposition on inhaled dose
    • Dolovich MB, Rhem R (1998) Impact of oropharyngeal deposition on inhaled dose. J Aerosol Med 11(S1):S112-S115
    • (1998) J Aerosol Med , vol.11 , Issue.S1 , pp. S112-S115
    • Dolovich, M.B.1    Rhem, R.2
  • 10
    • 33846076698 scopus 로고    scopus 로고
    • Degree of throat deposition can explain the variability in lung deposition of inhaled drugs
    • Borgström L, Olsson B, Thorsson L (2006) Degree of throat deposition can explain the variability in lung deposition of inhaled drugs. J Aerosol Med 19(4):473-483
    • (2006) J Aerosol Med , vol.19 , Issue.4 , pp. 473-483
    • Borgström, L.1    Olsson, B.2    Thorsson, L.3
  • 11
    • 0033286451 scopus 로고    scopus 로고
    • Particle deposition in a cast of human oral airways
    • Cheng YS, Zhou Y, Chen BT (1999) Particle deposition in a cast of human oral airways. Aerosol Sci Technol 31(4):286-300
    • (1999) Aerosol Sci Technol , vol.31 , Issue.4 , pp. 286-300
    • Cheng, Y.S.1    Zhou, Y.2    Chen, B.T.3
  • 12
    • 0026995555 scopus 로고
    • Apparatus and method for measuring regional distribution of therapeutic aerosols and comparing delivery systems
    • Swift DL (1992) Apparatus and method for measuring regional distribution of therapeutic aerosols and comparing delivery systems. J Aerosol Sci 23(S1):S495-S498
    • (1992) J Aerosol Sci , vol.23 , Issue.S1 , pp. S495-S498
    • Swift, D.L.1
  • 13
    • 0029144971 scopus 로고
    • In vitro properties of pressurized metered dose inhalers with and without spacer devices
    • Berg E (1995) In vitro properties of pressurized metered dose inhalers with and without spacer devices. J Aerosol Med 8(S3):S3-S11
    • (1995) J Aerosol Med , vol.8 , Issue.S3 , pp. S3-S11
    • Berg, E.1
  • 14
    • 0031832650 scopus 로고    scopus 로고
    • Metered dose inhaler aerosol deposition in a model of the human respiratory system and a comparison with clinical deposition studies
    • Velasquez DJ, Gabrio B (1998) Metered dose inhaler aerosol deposition in a model of the human respiratory system and a comparison with clinical deposition studies. J Aerosol Med 11(S1):S23-S28
    • (1998) J Aerosol Med , vol.11 , Issue.S1 , pp. S23-S28
    • Velasquez, D.J.1    Gabrio, B.2
  • 15
    • 62149094354 scopus 로고    scopus 로고
    • Pharmacokinetic, pharmacodynamic, effi cacy, and safety data from two randomized, doubleblind studies in patients with asthma and an in vitro study comparing two dry-powder inhalers delivering a combination of salmeterol 50 ?g and fl uticasone propionate 250 ?g: Implications for establishing bioequivalence of inhaled products
    • Daley-Yates PT, Parkins DA, Thomas MJ, Gillett B, House KW, Ortega HG (2009) Pharmacokinetic, pharmacodynamic, effi cacy, and safety data from two randomized, doubleblind studies in patients with asthma and an in vitro study comparing two dry-powder inhalers delivering a combination of salmeterol 50 ?g and fl uticasone propionate 250 ?g: implications for establishing bioequivalence of inhaled products. Clin Thera 31(2):370-385
    • (2009) Clin Thera , vol.31 , Issue.2 , pp. 370-385
    • Daley-Yates, P.T.1    Parkins, D.A.2    Thomas, M.J.3    Gillett, B.4    House, K.W.5    Ortega, H.G.6
  • 16
    • 3242722612 scopus 로고    scopus 로고
    • In vitro intersubject and intrasubject deposition measurements in realistic mouth-throat geometries
    • Grgic B, Finlay WH, Burnell PKP, Heenan AF (2004) In vitro intersubject and intrasubject deposition measurements in realistic mouth-throat geometries. J Aerosol Sci 35(8):1025-1040
    • (2004) J Aerosol Sci , vol.35 , Issue.8 , pp. 1025-1040
    • Grgic, B.1    Finlay, W.H.2    Burnell, P.K.P.3    Heenan, A.F.4
  • 17
    • 84871426935 scopus 로고    scopus 로고
    • New validated extrathoracic and pulmonary deposition models for infants and children
    • Dalby RN, Byron PR, Peart J, Suman JD, Farr SJ, Young PM (eds). Davis HealthCare International Publishing, River Grove, IL
    • Finlay WH (2012) New validated extrathoracic and pulmonary deposition models for infants and children. In: Dalby RN, Byron PR, Peart J, Suman JD, Farr SJ, Young PM (eds) Respiratory drug delivery-2012. Davis HealthCare International Publishing, River Grove, IL, pp 325-336
    • (2012) Respiratory Drug delivery-2012 , pp. 325-336
    • Finlay, W.H.1
  • 18
    • 79955974555 scopus 로고    scopus 로고
    • In vitro deposition measurement of inhaled micrometer-sized particles in nasal airways of children and adolescents during nose breathing
    • Golshahi L, Noga ML, Thompson RB, Finlay WH (2011) In vitro deposition measurement of inhaled micrometer-sized particles in nasal airways of children and adolescents during nose breathing. J Aerosol Sci 42(7):474-488
    • (2011) J Aerosol Sci , vol.42 , Issue.7 , pp. 474-488
    • Golshahi, L.1    Noga, M.L.2    Thompson, R.B.3    Finlay, W.H.4
  • 19
    • 84859601531 scopus 로고    scopus 로고
    • Deposition of inhaled micrometer-sized particles in oropharyngeal airway replicas of children at constant fl ow rates
    • Golshahi L, Noga ML, Finlay WH (2012) Deposition of inhaled micrometer-sized particles in oropharyngeal airway replicas of children at constant fl ow rates. J Aerosol Sci 49(1):21-31
    • (2012) J Aerosol Sci , vol.49 , Issue.1 , pp. 21-31
    • Golshahi, L.1    Noga, M.L.2    Finlay, W.H.3
  • 20
    • 85192417265 scopus 로고    scopus 로고
    • Anticholinergics in combination bronchodilator therapy in COPD
    • Spector SL (ed). Dekker, New York, NY
    • Rennard SI (2005) Anticholinergics in combination bronchodilator therapy in COPD. In: Spector SL (ed) Anticholinergic agents in the lower and upper airways. Dekker, New York, NY, pp 97-111
    • (2005) Anticholinergic Agents in the Lower and Upper Airways , pp. 97-111
    • Rennard, S.I.1
  • 22
    • 84944042354 scopus 로고    scopus 로고
    • In vivo measurements of lung dose
    • Bisgaard H, O?Callaghan C, Smaldone GC (eds). Dekker, New York, NY
    • Everard ML, Dolovich MB (2002) In vivo measurements of lung dose. In: Bisgaard H, O?Callaghan C, Smaldone GC (eds) Drug delivery to the lung. Dekker, New York, NY, pp 173-209
    • (2002) Drug Delivery to the Lung , pp. 173-209
    • Everard, M.L.1    Dolovich, M.B.2
  • 23
    • 0027532038 scopus 로고
    • Lung dose, distribution, and clinical response to therapeutic aerosols
    • Dolovich MB (1993) Lung dose, distribution, and clinical response to therapeutic aerosols. Aerosol Sci Technol 18(3):230-240
    • (1993) Aerosol Sci Technol , vol.18 , Issue.3 , pp. 230-240
    • Dolovich, M.B.1
  • 26
    • 1642515071 scopus 로고    scopus 로고
    • Cascade impactors for the size characterization of aerosols from medical inhalers: Their uses and limitations
    • Mitchell JP, Nagel MW (2003) Cascade impactors for the size characterization of aerosols from medical inhalers: their uses and limitations. J Aerosol Med 16(4):341-377
    • (2003) J Aerosol Med , vol.16 , Issue.4 , pp. 341-377
    • Mitchell, J.P.1    Nagel, M.W.2
  • 27
    • 0000913821 scopus 로고    scopus 로고
    • Effect of inlet throat on the correlation between measured fi ne particle dose and lung deposition
    • Dalby RN, Byron PR, Farr SJ (eds). Interpharm Press, Buffalo Grove, IL
    • Olsson B, Borgstrom L, Asking L, Bondesson E (1996) Effect of inlet throat on the correlation between measured fi ne particle dose and lung deposition. In: Dalby RN, Byron PR, Farr SJ (eds) Respiratory drug delivery-V. Interpharm Press, Buffalo Grove, IL, pp 273-282
    • (1996) Respiratory Drug Delivery-V , pp. 273-282
    • Olsson, B.1    Borgstrom, L.2    Asking, L.3    Bondesson, E.4
  • 28
    • 12244259864 scopus 로고    scopus 로고
    • Dynamic change of the upper airway during inhalation via aerosol devices
    • Ehtezazi T, Horsfi eld MA, Barry PW, OCallaghan C (2004) Dynamic change of the upper airway during inhalation via aerosol devices. J Aerosol Med 17(4):325-334
    • (2004) J Aerosol Med , vol.17 , Issue.4 , pp. 325-334
    • Ehtezazi, T.1    Horsfield, M.A.2    Barry, P.W.3    Ocallaghan, C.4
  • 29
    • 17644387588 scopus 로고    scopus 로고
    • Suitability of the upper airway models obtained from MRI studies in simulating drug lung deposition from inhalers
    • Ehtezazi T, Southern KW, Allanson D, Jenkinson I, Ocallaghan C (2005) Suitability of the upper airway models obtained from MRI studies in simulating drug lung deposition from inhalers. Pharm Res 22(1):166-170
    • (2005) Pharm Res , vol.22 , Issue.1 , pp. 166-170
    • Ehtezazi, T.1    Southern, K.W.2    Allanson, D.3    Jenkinson, I.4    Ocallaghan, C.5
  • 30
    • 0000696217 scopus 로고
    • The oral airway-A conduit or collector for pharmaceutical aerosols
    • Byron P, Dalby RN, Farr SJ (eds). Interpharm Press, Buffalo Grove, IL
    • Swift DL (1994) The oral airway-a conduit or collector for pharmaceutical aerosols. In: Byron P, Dalby RN, Farr SJ (eds) Respiratory drug delivery IV. Interpharm Press, Buffalo Grove, IL, pp 187-195
    • (1994) Respiratory Drug Delivery IV , pp. 187-195
    • Swift, D.L.1
  • 32
    • 1642515060 scopus 로고    scopus 로고
    • Studies of the human oropharyngeal airspaces using magnetic resonance imaging. I. Validation of a three-dimensional MRI method for producing ex vivo virtual and physical casts of the oropharyngeal airways during inspiration
    • McRobbie DW, Pritchard S, Quest RA (2003) Studies of the human oropharyngeal airspaces using magnetic resonance imaging. I. Validation of a three-dimensional MRI method for producing ex vivo virtual and physical casts of the oropharyngeal airways during inspiration. J Aerosol Med 16(4):401-415
    • (2003) J Aerosol Med , vol.16 , Issue.4 , pp. 401-415
    • McRobbie, D.W.1    Pritchard, S.2    Quest, R.A.3
  • 33
    • 38049123487 scopus 로고    scopus 로고
    • Asymmetrical aerosol deposition in an idealized mouth with a DPI mouthpiece inlet
    • Ilie M, Matida EA, Finlay WH (2008) Asymmetrical aerosol deposition in an idealized mouth with a DPI mouthpiece inlet. Aerosol Sci Technol 42(1):10-17
    • (2008) Aerosol Sci Technol , vol.42 , Issue.1 , pp. 10-17
    • Ilie, M.1    Matida, E.A.2    Finlay, W.H.3
  • 34
    • 34648816355 scopus 로고    scopus 로고
    • In vivo-in vitro comparison of deposition in three mouth-throat models with Qvar and Turbuhaler inhalers
    • Zhang Y, Gilbertson K, Finlay WH (2007) In vivo-in vitro comparison of deposition in three mouth-throat models with Qvar and Turbuhaler inhalers. J Aerosol Med 20(3):227-235
    • (2007) J Aerosol Med , vol.20 , Issue.3 , pp. 227-235
    • Zhang, Y.1    Gilbertson, K.2    Finlay, W.H.3
  • 35
    • 0034019232 scopus 로고    scopus 로고
    • On the suitability of k- turbulence modeling for aerosol deposition in the mouth and throat: A comparison with experiment
    • Stapleton KW, Guentsch E, Hoskinson MK, Finlay WH (2000) On the suitability of k- turbulence modeling for aerosol deposition in the mouth and throat: a comparison with experiment. J Aerosol Sci 31(6):731-749
    • (2000) J Aerosol Sci , vol.31 , Issue.6 , pp. 731-749
    • Stapleton, K.W.1    Guentsch, E.2    Hoskinson, M.K.3    Finlay, W.H.4
  • 36
    • 0345256446 scopus 로고    scopus 로고
    • Regional aerosol deposition and fl ow measurements in an idealized mouth and throat
    • Grgic B, Finlay WH, Heenan AF (2004) Regional aerosol deposition and fl ow measurements in an idealized mouth and throat. J Aerosol Sci 35(1):21-32
    • (2004) J Aerosol Sci , vol.35 , Issue.1 , pp. 21-32
    • Grgic, B.1    Finlay, W.H.2    Heenan, A.F.3
  • 37
    • 79551504542 scopus 로고    scopus 로고
    • Structure and function of the respiratory system
    • Bisgaard H, O?Callaghan C, Smaldone GC (eds). Dekker, New York, NY
    • Stocks J, Hislop AA (2002) Structure and function of the respiratory system. In: Bisgaard H, O?Callaghan C, Smaldone GC (eds) Drug delivery to the lung. Dekker, New York, NY, pp 47-104
    • (2002) Drug Delivery to the Lung , pp. 47-104
    • Stocks, J.1    Hislop, A.A.2
  • 38
    • 3242687759 scopus 로고    scopus 로고
    • Inhaler devices in infants and children: Challenges and solutions
    • Everard ML (2004) Inhaler devices in infants and children: challenges and solutions. J Aerosol Med 17(2):186-195
    • (2004) J Aerosol Med , vol.17 , Issue.2 , pp. 186-195
    • Everard, M.L.1
  • 40
    • 78649933012 scopus 로고    scopus 로고
    • Relative precision of inhaler aerodynamic particle size distribution (APSD) metrics by full resolution and abbreviated Andersen Cascade Impactors (ACIs): Part 2-Investigation of bias in extra-fi ne mass fraction with AIM-HRT impactor
    • Mitchell JP, Nagel MW, Doyle C, Ali RS, Avvakoumova V, Christopher D, Quiroz J, Strickland H, Tougas T, Lyapustina S (2010) Relative precision of inhaler aerodynamic particle size distribution (APSD) metrics by full resolution and abbreviated Andersen Cascade Impactors (ACIs): Part 2-Investigation of bias in extra-fi ne mass fraction with AIM-HRT impactor. AAPS PharmSciTech 11(3):1115-1118
    • (2010) AAPS Pharm. Sci. Tech , vol.11 , Issue.3 , pp. 1115-1118
    • Mitchell, J.P.1    Nagel, M.W.2    Doyle, C.3    Ali, R.S.4    Avvakoumova, V.5    Christopher, D.6    Quiroz, J.7    Strickland, H.8    Tougas, T.9    Lyapustina, S.10
  • 41
    • 84890233842 scopus 로고    scopus 로고
    • Comparative performance evaluation of the Westech Fine Particle Dose (FPD) impactor
    • Dalby RN, Byron PR, Peart J, Suman JD, Farr SJ, Young PM (eds). Davis HealthCare International Publishing, River Grove, IL
    • Chambers FE, Smurthwaite M (2012) Comparative performance evaluation of the Westech Fine Particle Dose (FPD) impactor. In: Dalby RN, Byron PR, Peart J, Suman JD, Farr SJ, Young PM (eds) Respiratory drug delivery-2012. Davis HealthCare International Publishing, River Grove, IL, pp 553-558
    • (2012) Respiratory Drug delivery-2012 , pp. 553-558
    • Chambers, F.E.1    Smurthwaite, M.2
  • 42
    • 84864714719 scopus 로고    scopus 로고
    • Adapting the Abbreviated Impactor Measurement (AIM) concept to make appropriate inhaler aerosol measurements to compare with clinical data: A scoping study with the "alberta" Idealized Throat (AIT) inlet
    • Mitchell JP, Copley M, Sizer Y, Russell T, Solomon D (2012) Adapting the Abbreviated Impactor Measurement (AIM) concept to make appropriate inhaler aerosol measurements to compare with clinical data: a scoping study with the "Alberta" Idealized Throat (AIT) inlet. J Aerosol Med Pulm Drug Deliv 25(4):188-197
    • (2012) J Aerosol Med Pulm Drug Deliv , vol.25 , Issue.4 , pp. 188-197
    • Mitchell, J.P.1    Copley, M.2    Sizer, Y.3    Russell, T.4    Solomon, D.5
  • 43
    • 72949109105 scopus 로고    scopus 로고
    • The interaction between the oropharyngeal geometry and aerosols via pressurized metered dose inhalers
    • Ehtezazi T, Saleem I, Shrubb I, Allanson ID, Ocallaghan C (2010) The interaction between the oropharyngeal geometry and aerosols via pressurized metered dose inhalers. Pharm Res 27(1):175-186
    • (2010) Pharm Res , vol.27 , Issue.1 , pp. 175-186
    • Ehtezazi, T.1    Saleem, I.2    Shrubb, I.3    Allanson, I.D.4    Ocallaghan, C.5
  • 44
    • 67549136514 scopus 로고    scopus 로고
    • The abbreviated impactor measurement (AIM) concept: Part 1-infl uence of particle bounce and re-entrainment-evaluation with a "dry" pressurized metered dose inhaler (MDI)-based formulation
    • Mitchell JP, Nagel MW, Avvakoumova V, MacKay H, Ali R (2009) The abbreviated impactor measurement (AIM) concept: part 1-infl uence of particle bounce and re-entrainment-evaluation with a "dry" pressurized metered dose inhaler (MDI)-based formulation. AAPS PharmSciTech 10(1):243-251
    • (2009) AAPS Pharm Sci Tech , vol.10 , Issue.1 , pp. 243-251
    • Mitchell, J.P.1    Nagel, M.W.2    Avvakoumova, V.3    Mackay, H.4    Ali, R.5
  • 45
    • 84864678487 scopus 로고    scopus 로고
    • Evaluating the Alberta throat: An innovation to support the acquisition of more clinically applicable aerosol aerodynamic particle size distribution (APSD) data in oral inhaled product (OIP) development
    • Copley M, Mitchell J, Solomon D (2011) Evaluating the Alberta throat: an innovation to support the acquisition of more clinically applicable aerosol aerodynamic particle size distribution (APSD) data in oral inhaled product (OIP) development. Inhalation 5(4):12-16
    • (2011) Inhalation , vol.5 , Issue.4 , pp. 12-16
    • Copley, M.1    Mitchell, J.2    Solomon, D.3
  • 46
    • 84864692372 scopus 로고    scopus 로고
    • Infl uence of stage effi ciency curves on interpretation of abbreviated impactor data
    • The Aerosol Society, Edinburgh, UK. Visited 4 Aug 2012
    • Roberts DL, Mitchell JP (2011) Infl uence of stage effi ciency curves on interpretation of abbreviated impactor data. Drug delivery to the lungs-22, The Aerosol Society, Edinburgh, UK, pp 177-180. Available at: http://ddl-conference.org.uk/index.php?q=previous-conferences. Visited 4 Aug 2012
    • (2011) Drug Delivery to the lungs-22 , pp. 177-180
    • Roberts, D.L.1    Mitchell, J.P.2
  • 47
    • 9244228466 scopus 로고    scopus 로고
    • Canadian Standards Association standard CAN/CSA/Z264.1-02:2002: A new voluntary standard for spacers and holding chambers used with pressurized metered-dose inhalers
    • Dolovich MB, Mitchell JP (2004) Canadian Standards Association standard CAN/CSA/Z264.1-02:2002: a new voluntary standard for spacers and holding chambers used with pressurized metered-dose inhalers. Can Respir J 11(7):489-495
    • (2004) Can Respir J , vol.11 , Issue.7 , pp. 489-495
    • Dolovich, M.B.1    Mitchell, J.P.2
  • 48
    • 84864701331 scopus 로고    scopus 로고
    • Advances in models for laboratory testing of inhalers: There?s more to it than meets the nose or mouth-The ADAM face models
    • Dalby RN, Byron PR, Peart J, Suman JD, Farr SJ, Young PM (eds). Davis Healthcare International Publishing LLC, River Grove, IL
    • Mitchell JP, Nagel M, Finlay B (2011) Advances in models for laboratory testing of inhalers: there?s more to it than meets the nose or mouth-The ADAM face models. In: Dalby RN, Byron PR, Peart J, Suman JD, Farr SJ, Young PM (eds) Respiratory drug delivery Europe-2011. Davis Healthcare International Publishing LLC, River Grove, IL, pp 457-461
    • (2011) Respiratory Drug Delivery Europe-2011 , pp. 457-461
    • Mitchell, J.P.1    Nagel, M.2    Finlay, B.3
  • 51
    • 0034278559 scopus 로고    scopus 로고
    • In-vitro characterisation of metered dose inhaler versus dry powder inhaler glucocorticoid products: Infl uence of inspiratory fl ow rates
    • Feddah MR, Brown KF, Gipps EM, Davies NM (2000) In-vitro characterisation of metered dose inhaler versus dry powder inhaler glucocorticoid products: infl uence of inspiratory fl ow rates. J Pharm Pharm Sci 3(3):317-324
    • (2000) J Pharm Pharm Sci , vol.3 , Issue.3 , pp. 317-324
    • Feddah, M.R.1    Brown, K.F.2    Gipps, E.M.3    Davies, N.M.4
  • 52
    • 0032171467 scopus 로고    scopus 로고
    • Design, validation and initial testing of the Electronic Lung™ device
    • Burnell PKP, Malton A, Reavill K, Ball MHE (1998) Design, validation and initial testing of the Electronic Lung™ device. J Aerosol Sci 29(8):1011-1025
    • (1998) J Aerosol Sci , vol.29 , Issue.8 , pp. 1011-1025
    • Burnell, P.K.P.1    Malton, A.2    Reavill, K.3    Ball, M.H.E.4
  • 53
    • 84907873432 scopus 로고    scopus 로고
    • Assessment of early screening methodology using the Next Generation and Fast Screen Impactor systems
    • The Aerosol Society, Edinburgh, UK,. Visited 4 Aug 2012
    • Hamilton M, Daniels G (2011) Assessment of early screening methodology using the Next Generation and Fast Screen Impactor systems. Drug Delivery to the Lungs-22, The Aerosol Society, Edinburgh, UK, 22:355-358. Available at: http://ddl-conference.org.uk/index.php?q=previous-conferences. Visited 4 Aug 2012
    • (2011) Drug Delivery to the Lungs-22 , vol.22 , pp. 355-358
    • Hamilton, M.1    Daniels, G.2
  • 54
    • 84903478236 scopus 로고    scopus 로고
    • Apparatus and process for aerosol size measurement at varying gas flow rates
    • US Patent
    • Miller NC (2002) Apparatus and process for aerosol size measurement at varying gas fl ow rates. US Patent 6,435,004-B1
    • (2002)
    • Miller, N.C.1
  • 55
    • 79954424758 scopus 로고    scopus 로고
    • Comparing aerosol size distributions that penetrate mouth-throat models under realistic inhalation conditions
    • Dalby RN, Byron PR, Peart J, Suman JD, Farr SJ, Young PM (eds). Davis Healthcare International Publishing, River Grove, IL
    • Olson B, Berg E, Svensson M (2010) Comparing aerosol size distributions that penetrate mouth-throat models under realistic inhalation conditions. In: Dalby RN, Byron PR, Peart J, Suman JD, Farr SJ, Young PM (eds) Respiratory drug delivery-2010. Davis Healthcare International Publishing, River Grove, IL, pp 225-234
    • (2010) Respiratory Drug delivery-2010 , pp. 225-234
    • Olson, B.1    Berg, E.2    Svensson, M.3
  • 56
    • 84864664212 scopus 로고    scopus 로고
    • Clinically relevant test methods to establish in vitro equivalence for spacers and valved holding chambers used with pressurized metered dose inhalers (MDIs)
    • Mitchell JP, Dolovich MB (2012) Clinically relevant test methods to establish in vitro equivalence for spacers and valved holding chambers used with pressurized metered dose inhalers (MDIs). J Aerosol Med Pulm Drug Deliv 25(4):217-242
    • (2012) J Aerosol Med Pulm Drug Deliv , vol.25 , Issue.4 , pp. 217-242
    • Mitchell, J.P.1    Dolovich, M.B.2
  • 57
    • 13544258981 scopus 로고    scopus 로고
    • In my opinion: Interview with the expert
    • Dolovich MB (2004) In my opinion: interview with the expert. Pediatr Asthma Allergy Immunol 17(4):292-300
    • (2004) Pediatr Asthma Allergy Immunol , vol.17 , Issue.4 , pp. 292-300
    • Dolovich, M.B.1
  • 58
    • 34247595354 scopus 로고    scopus 로고
    • Design of facemasks for delivery of aerosol-based medication via pressurized metered dose inhaler with valved holding chamber: Key issues that affect performance
    • Morton RW, Mitchell JP (2007) Design of facemasks for delivery of aerosol-based medication via pressurized metered dose inhaler with valved holding chamber: Key issues that affect performance. J Aerosol Med 20(S1):S29-S45
    • (2007) J Aerosol Med , vol.20 , Issue.S1 , pp. S29-S45
    • Morton, R.W.1    Mitchell, J.P.2
  • 59
    • 0032762858 scopus 로고    scopus 로고
    • In vitro comparison of salbutamol hydrofl uoroalkane (Airomir) metered dose inhaler aerosols inhaled during pediatric tidal breathing from fi ve valved holding chambers
    • Finlay WH, Zuberbuhler P (1999) In vitro comparison of salbutamol hydrofl uoroalkane (Airomir) metered dose inhaler aerosols inhaled during pediatric tidal breathing from fi ve valved holding chambers. J Aerosol Med 12(4):285-291
    • (1999) J Aerosol Med , vol.12 , Issue.4 , pp. 285-291
    • Finlay, W.H.1    Zuberbuhler, P.2
  • 60
    • 33748155376 scopus 로고    scopus 로고
    • Force-dependent static dead space of face masks used with holding chambers
    • Shah SA, Berlinski A, Rubin BK (2006) Force-dependent static dead space of face masks used with holding chambers. Respir Care 51(2):140-144
    • (2006) Respir Care , vol.51 , Issue.2 , pp. 140-144
    • Shah, S.A.1    Berlinski, A.2    Rubin, B.K.3
  • 61
    • 80053141725 scopus 로고    scopus 로고
    • Validation of a new model infant face with nasopharynx for the testing of valved holding chambers (VHCs) with facemask as a patient interface
    • Dalby RN, Byron PR, Peart J, Suman JD, Farr SJ (eds). Davis Healthcare International Publishing LLC, River Grove, IL
    • Mitchell JP, Finlay JB, Nuttall JM, Limbrick MR, Nagel MW, Avvakoumova V, MacKay H, Ali RS, Doyle CC (2011) Validation of a new model infant face with nasopharynx for the testing of valved holding chambers (VHCs) with facemask as a patient interface. In: Dalby RN, Byron PR, Peart J, Suman JD, Farr SJ (eds) Respiratory drug delivery-2010. Davis Healthcare International Publishing LLC, River Grove, IL, pp 777-780
    • (2011) Respiratory Drug delivery-2010 , pp. 777-780
    • Mitchell, J.P.1    Finlay, J.B.2    Nuttall, J.M.3    Limbrick, M.R.4    Nagel, M.W.5    Avvakoumova, V.6    Mackay, H.7    Ali, R.S.8    Doyle, C.C.9
  • 62
    • 45949102259 scopus 로고    scopus 로고
    • Appropriate face models for evaluating drug delivery in the laboratory: The current situation and prospects for future advances
    • Mitchell JP (2008) Appropriate face models for evaluating drug delivery in the laboratory: the current situation and prospects for future advances. J Aerosol Med 21(1):1-15
    • (2008) J Aerosol Med , vol.21 , Issue.1 , pp. 1-15
    • Mitchell, J.P.1
  • 63
    • 56049107464 scopus 로고    scopus 로고
    • Deposition of micrometer-sized aerosol particles in infant nasal airway replicas
    • Storey-Bischoff J, Noga M, Finlay WH (2008) Deposition of micrometer-sized aerosol particles in infant nasal airway replicas. J Aerosol Sci 39(12):1055-1065
    • (2008) J Aerosol Sci , vol.39 , Issue.12 , pp. 1055-1065
    • Storey-Bischoff, J.1    Noga, M.2    Finlay, W.H.3
  • 64
    • 0031860377 scopus 로고    scopus 로고
    • The current laboratory determination of "respirable Mass" is not clinically relevant
    • Newhouse MT (1998) The current laboratory determination of "Respirable Mass" is not clinically relevant. J Aerosol Med 11(S1):S122-S132
    • (1998) J Aerosol Med , vol.11 , Issue.S1 , pp. S122-S132
    • Newhouse, M.T.1
  • 65
    • 0344513087 scopus 로고    scopus 로고
    • Pulmonary drug delivery. Part I: Physiological factors affecting therapeutic effectiveness of aerosolized medications
    • Labiris NR, Dolovich MB (2003) Pulmonary drug delivery. Part I: physiological factors affecting therapeutic effectiveness of aerosolized medications. Br J Clin Pharmacol 5(12):588-599
    • (2003) Br J Clin Pharmacol , vol.5 , Issue.12 , pp. 588-599
    • Labiris, N.R.1    Dolovich, M.B.2
  • 66
    • 12244300136 scopus 로고    scopus 로고
    • Next generation pharmaceutical impactor: A new impactor for pharmaceutical inhaler testing. Part III. Extension of archival calibration to 15 L/min
    • Marple VA, Olson BA, Santhanakrishnan K, Mitchell JP, Murray SC, Hudson-Curtis BL (2004) Next generation pharmaceutical impactor: a new impactor for pharmaceutical inhaler testing. Part III. Extension of archival calibration to 15 L/min. J Aerosol Med 17(4):335-343
    • (2004) J Aerosol Med , vol.17 , Issue.4 , pp. 335-343
    • Marple, V.A.1    Olson, B.A.2    Santhanakrishnan, K.3    Mitchell, J.P.4    Murray, S.C.5    Hudson-Curtis, B.L.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.