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Volumn 17, Issue 4, 2004, Pages 325-334

Dynamic change of the upper airway during inhalation via aerosol delivery devices

Author keywords

Aerosols; Dry powder inhaler; Magnetic resonance imaging (MRI); Metered dose inhaler; Spacer; Upper airway

Indexed keywords

ADULT; AEROSOL; AIRFLOW; ARTICLE; ASTHMA; CHRONIC OBSTRUCTIVE LUNG DISEASE; CONTROLLED STUDY; CYSTIC FIBROSIS; DRUG DELIVERY SYSTEM; DRY POWDER; FEMALE; HUMAN; IMAGE ANALYSIS; IMAGE RECONSTRUCTION; INHALATION SPACER; LARYNX; MALE; METERED DOSE INHALER; MOUTH CAVITY; NORMAL HUMAN; NUCLEAR MAGNETIC RESONANCE IMAGING; OROPHARYNX; TONGUE; TRACHEA; UPPER RESPIRATORY TRACT;

EID: 12244259864     PISSN: 08942684     EISSN: None     Source Type: Journal    
DOI: 10.1089/jam.2004.17.325     Document Type: Article
Times cited : (30)

References (32)
  • 1
    • 0033989628 scopus 로고    scopus 로고
    • Variability in lung deposition of inhaled drug, within and between asthmatic patients, with a pMDI and a dry powder inhaler, Turbuhaler
    • Borgstrom, L., Bengtsson, T., Derom, E., et al. 2000. Variability in lung deposition of inhaled drug, within and between asthmatic patients, with a pMDI and a dry powder inhaler, Turbuhaler. Int. J. Pharm. 193:227-230.
    • (2000) Int. J. Pharm. , vol.193 , pp. 227-230
    • Borgstrom, L.1    Bengtsson, T.2    Derom, E.3
  • 2
    • 0029972560 scopus 로고    scopus 로고
    • The inhalation device influences lung deposition and bronchodilating effect of terbutaline
    • Borgstrom, L., Derom, E., Stahl, E., et al. 1996. The inhalation device influences lung deposition and bronchodilating effect of terbutaline. Am. J. Respir. Crit. Care Med. 153:1636-1640.
    • (1996) Am. J. Respir. Crit. Care Med. , vol.153 , pp. 1636-1640
    • Borgstrom, L.1    Derom, E.2    Stahl, E.3
  • 3
    • 0032240027 scopus 로고    scopus 로고
    • The lung as an alternative route of delivery for insulin in controlling postprandial glucose levels in patients with diabetes
    • Laube, B.L., Benedict, G.W., and Dobs, A.S. 1998. The lung as an alternative route of delivery for insulin in controlling postprandial glucose levels in patients with diabetes. Chest 114:1734-1739.
    • (1998) Chest , vol.114 , pp. 1734-1739
    • Laube, B.L.1    Benedict, G.W.2    Dobs, A.S.3
  • 4
    • 0031859158 scopus 로고    scopus 로고
    • Pulmonary administration of aerosolized fentanyl: Pharmacokinetic analysis of systemic delivery
    • Mather, L.E., Woodhouse, A., Ward, M.E., et al. 1998. Pulmonary administration of aerosolized fentanyl: pharmacokinetic analysis of systemic delivery. Br. J. Clin. Pharmacol. 46:37-43.
    • (1998) Br. J. Clin. Pharmacol. , vol.46 , pp. 37-43
    • Mather, L.E.1    Woodhouse, A.2    Ward, M.E.3
  • 5
    • 0029861605 scopus 로고    scopus 로고
    • On the use of computational fluid dynamics for simulating flow and particle deposition in the human respiratory tract
    • Finlay, W.H., Stapleton, K.W., and Yokota, J. 1996. On the use of computational fluid dynamics for simulating flow and particle deposition in the human respiratory tract. J. Aerosol Med. 9:329-341.
    • (1996) J. Aerosol Med. , vol.9 , pp. 329-341
    • Finlay, W.H.1    Stapleton, K.W.2    Yokota, J.3
  • 7
    • 0034864345 scopus 로고    scopus 로고
    • In vitro monodisperse aerosol deposition in a mouth and throat with six different inhalation devices
    • DeHaan, W.H., and Finlay, W.H. 2001. In vitro monodisperse aerosol deposition in a mouth and throat with six different inhalation devices. J. Aerosol Med. 14:361-367.
    • (2001) J. Aerosol Med. , vol.14 , pp. 361-367
    • DeHaan, W.H.1    Finlay, W.H.2
  • 8
    • 85012509202 scopus 로고
    • Mouth and throat deposition of 3.6-μm radiolabeled particles in asthmatics
    • Svartengren, M., Anderson, M., Bylin, G., et al. 1991. Mouth and throat deposition of 3.6-μm radiolabeled particles in asthmatics. J. Aerosol Med. 4:313-321.
    • (1991) J. Aerosol Med. , vol.4 , pp. 313-321
    • Svartengren, M.1    Anderson, M.2    Bylin, G.3
  • 9
    • 0028071388 scopus 로고
    • Deposition of inhaled particles in the mouth and throat of asthmatic subjects
    • Svartengren, K., Lindestad, P.A., Svartengren, M., et al. 1994. Deposition of inhaled particles in the mouth and throat of asthmatic subjects. Eur. Respir. J. 7: 1467-1473.
    • (1994) Eur. Respir. J. , vol.7 , pp. 1467-1473
    • Svartengren, K.1    Lindestad, P.A.2    Svartengren, M.3
  • 10
    • 0034019232 scopus 로고    scopus 로고
    • On the suitability of k-epsilon turbulence modeling for aerosol deposition in the mouth and throat: A comparison with experiment
    • Stapleton, K.W., Guentsch, E., Hoskinson, M.K., et al. 2000. On the suitability of k-epsilon turbulence modeling for aerosol deposition in the mouth and throat: a comparison with experiment. J. Aerosol Sci. 31:739-749.
    • (2000) J. Aerosol Sci. , vol.31 , pp. 739-749
    • Stapleton, K.W.1    Guentsch, E.2    Hoskinson, M.K.3
  • 11
    • 0031560934 scopus 로고    scopus 로고
    • Aerosol particle transport and deaggregation phenomena in the mouth and throat
    • Li, W.I., and Edwards, D.A. 1997. Aerosol particle transport and deaggregation phenomena in the mouth and throat. Adv. Drug Delivery Rev. 26:41-49.
    • (1997) Adv. Drug Delivery Rev. , vol.26 , pp. 41-49
    • Li, W.I.1    Edwards, D.A.2
  • 12
    • 0032171280 scopus 로고    scopus 로고
    • The macrotransport properties of aerosol particles in the human oral-pharyngeal region
    • Li, W.I., Perzl, M., Ferron, G.A., et al. 1998. The macrotransport properties of aerosol particles in the human oral-pharyngeal region. J. Aerosol Sci. 29: 995-1010.
    • (1998) J. Aerosol Sci. , vol.29 , pp. 995-1010
    • Li, W.I.1    Perzl, M.2    Ferron, G.A.3
  • 13
    • 0029118998 scopus 로고
    • Added external resistance reduces oropharyngeal deposition and increases lung deposition of aerosol particles in asthmatics
    • Svartengren, K., Lindestad, P., Svartengren, M., et al. 1995. Added external resistance reduces oropharyngeal deposition and increases lung deposition of aerosol particles in asthmatics. Am. J. Respir. Crit. Care Med. 152:32-37.
    • (1995) Am. J. Respir. Crit. Care Med. , vol.152 , pp. 32-37
    • Svartengren, K.1    Lindestad, P.2    Svartengren, M.3
  • 14
    • 0029380412 scopus 로고
    • Deposition of ultrafine aerosols in the head airways during natural breathing and during simulated breath-holding using replicate human upper airway casts
    • Cheng, K.H., Cheng, C.Y.S., Yeh, H.C., et al. 1995. Deposition of ultrafine aerosols in the head airways during natural breathing and during simulated breath-holding using replicate human upper airway casts. Aerosol Sci. Technol. 23:465-474.
    • (1995) Aerosol Sci. Technol. , vol.23 , pp. 465-474
    • Cheng, K.H.1    Cheng, C.Y.S.2    Yeh, H.C.3
  • 15
    • 0031959580 scopus 로고    scopus 로고
    • Upper airway imaging
    • Schwab, R.J. 1998. Upper airway imaging. Clin. Chest Med. 19:33-54.
    • (1998) Clin. Chest Med. , vol.19 , pp. 33-54
    • Schwab, R.J.1
  • 16
    • 0019825227 scopus 로고
    • Optimal delivery of aerosols from metered dose inhalers
    • Dolovich, M., Ruffin, R.E., Roberts, R., et al. 1981. Optimal delivery of aerosols from metered dose inhalers. Chest 80:911-915.
    • (1981) Chest , vol.80 , pp. 911-915
    • Dolovich, M.1    Ruffin, R.E.2    Roberts, R.3
  • 17
    • 0028964430 scopus 로고
    • A registration and interpolation procedure for subvoxel matching of serially acquired MR images
    • Hajnal, J.V., Saeed, N., Soar, E.J., et al. 1995. A registration and interpolation procedure for subvoxel matching of serially acquired MR images. J. Comput. Assist. Tomogr. 19:289-296.
    • (1995) J. Comput. Assist. Tomogr. , vol.19 , pp. 289-296
    • Hajnal, J.V.1    Saeed, N.2    Soar, E.J.3
  • 19
    • 0031770141 scopus 로고    scopus 로고
    • State-related changes in upper airway caliber and surrounding soft-tissue structures in normal subjects
    • Trudo, F.J., Gefter, W.B., Welch, K.C., et al. 1998. State-related changes in upper airway caliber and surrounding soft-tissue structures in normal subjects. Am. J. Respir. Crit. Care Med. 158:1259-1270.
    • (1998) Am. J. Respir. Crit. Care Med. , vol.158 , pp. 1259-1270
    • Trudo, F.J.1    Gefter, W.B.2    Welch, K.C.3
  • 20
    • 0028828708 scopus 로고
    • Upper airway and soft tissue anatomy in normal subjects and patients with sleep-disordered breathing. Significance of the lateral pharyngeal walls
    • Schwab, R.J., Gupta, K.B., Gefter, W.B., et al. 1995. Upper airway and soft tissue anatomy in normal subjects and patients with sleep-disordered breathing. Significance of the lateral pharyngeal walls. Am. J. Respir. Crit. Care Med. 152:1673-1689.
    • (1995) Am. J. Respir. Crit. Care Med. , vol.152 , pp. 1673-1689
    • Schwab, R.J.1    Gupta, K.B.2    Gefter, W.B.3
  • 21
    • 0033911733 scopus 로고    scopus 로고
    • Scintigraphic comparison of budesonide deposition from two dry powder inhalers
    • Newman, S.P., Pitcairn, G.R., Hirst, P.H., et al. 2000. Scintigraphic comparison of budesonide deposition from two dry powder inhalers. Eur. Respir. J. 16:178-183.
    • (2000) Eur. Respir. J. , vol.16 , pp. 178-183
    • Newman, S.P.1    Pitcairn, G.R.2    Hirst, P.H.3
  • 22
    • 0026579116 scopus 로고
    • Effects, side-effects and plasma-concentrations of terbutaline in adult asthmatics after inhaling from a dry powder inhaler device at different inhalation flows and volumes
    • Engel, T., Scharling, B., Skovsted, B., et al. 1992. Effects, side-effects and plasma-concentrations of terbutaline in adult asthmatics after inhaling from a dry powder inhaler device at different inhalation flows and volumes. Br. J. Clin. Pharmacol. 33:439-444.
    • (1992) Br. J. Clin. Pharmacol. , vol.33 , pp. 439-444
    • Engel, T.1    Scharling, B.2    Skovsted, B.3
  • 23
    • 0018887470 scopus 로고
    • Experimental determination of the regional deposition of aerosol particles in the human respiratory tract 1
    • Stahlhofen, W., Gebhart, J., and Heyder, J. 1980. Experimental determination of the regional deposition of aerosol particles in the human respiratory tract 1. Am. Ind. Hyg. Assoc. J. 41:385-398a.
    • (1980) Am. Ind. Hyg. Assoc. J. , vol.41
    • Stahlhofen, W.1    Gebhart, J.2    Heyder, J.3
  • 24
    • 0025596608 scopus 로고
    • Modeling and algebraic formulation of regional aerosol deposition in man
    • Rudolf, G., Kobrich, R., and Stahlhofen, W. 1990. Modeling and algebraic formulation of regional aerosol deposition in man. J. Aerosol. Sci. 21:s403-s406.
    • (1990) J. Aerosol. Sci. , vol.21
    • Rudolf, G.1    Kobrich, R.2    Stahlhofen, W.3
  • 25
    • 0022889862 scopus 로고
    • Deposition of particles in the human respiratory-tract in the size range 0.005-15 μm
    • Heyder, J., Gebhart, J., Rudolf, G., et al. 1986. Deposition of particles in the human respiratory-tract in the size range 0.005-15 μm. J. Aerosol Sci. 17:811-825.
    • (1986) J. Aerosol Sci. , vol.17 , pp. 811-825
    • Heyder, J.1    Gebhart, J.2    Rudolf, G.3
  • 26
    • 0028179827 scopus 로고
    • Modeling the deposition of inhaled powdered drug aerosols
    • Clark, A.R., and Egan, M. 1994. Modeling the deposition of inhaled powdered drug aerosols. J. Aerosol Sci. 25:175-186.
    • (1994) J. Aerosol Sci. , vol.25 , pp. 175-186
    • Clark, A.R.1    Egan, M.2
  • 27
    • 0031804614 scopus 로고    scopus 로고
    • Mouth and oropharyngeal deposition of pharmaceutical aerosols
    • Clark, A.R., Newman, S.P., and Dasovich, N. 1998. Mouth and oropharyngeal deposition of pharmaceutical aerosols. J. Aerosol Med. 11:S116-S121.
    • (1998) J. Aerosol Med. , vol.11
    • Clark, A.R.1    Newman, S.P.2    Dasovich, N.3
  • 28
    • 0000913821 scopus 로고    scopus 로고
    • Effect of inlet throat on the correlation between measured fine particle dose and lung deposition
    • R.N. Dalby, P.R. Byron, and S.J. Farr, eds. Interpharm Press, Buffalo Grove, IL
    • Olsson, B., Borgstrom, L., Asking, L., et al. 1996. Effect of inlet throat on the correlation between measured fine particle dose and lung deposition. In R.N. Dalby, P.R. Byron, and S.J. Farr, eds. Respiratory Drug Delivery V. Interpharm Press, Buffalo Grove, IL, 273-281.
    • (1996) Respiratory Drug Delivery V , pp. 273-281
    • Olsson, B.1    Borgstrom, L.2    Asking, L.3
  • 29
    • 0034862979 scopus 로고    scopus 로고
    • Mouthpiece diameter affects deposition efficiency in cast models of the human oral airways
    • Lin, T.C., Breysse, P.N., Laube, B.L., et al. 2001. Mouthpiece diameter affects deposition efficiency in cast models of the human oral airways. J. Aerosol Med. 14:335-341.
    • (2001) J. Aerosol Med. , vol.14 , pp. 335-341
    • Lin, T.C.1    Breysse, P.N.2    Laube, B.L.3
  • 30
    • 0031042761 scopus 로고    scopus 로고
    • Toward articulatory-acoustic models for liquid approximants based on MRI and EPG data. Part I. The laterals
    • Narayanan, S.S., Alwan, A.A., and Haker, K. 1997. Toward articulatory-acoustic models for liquid approximants based on MRI and EPG data. Part I. The laterals. J. Acoust. Soc. Am. 101:1064-1077.
    • (1997) J. Acoust. Soc. Am. , vol.101 , pp. 1064-1077
    • Narayanan, S.S.1    Alwan, A.A.2    Haker, K.3
  • 31
    • 0032851604 scopus 로고    scopus 로고
    • Geometry, kinematics, and acoustics of Tamil liquid consonants
    • Narayanan, S., Byrd, D., and Kaun, A. 1999. Geometry, kinematics, and acoustics of Tamil liquid consonants. J. Acoust. Soc. Am. 106:1993-2007.
    • (1999) J. Acoust. Soc. Am. , vol.106 , pp. 1993-2007
    • Narayanan, S.1    Byrd, D.2    Kaun, A.3
  • 32
    • 0032730581 scopus 로고    scopus 로고
    • Functional MR with use of FLASH sequences in the evaluation of the phono-articulatory tract
    • Meduri, S., Bazzocchi, M., Zuiani, C., et al. 1999. Functional MR with use of FLASH sequences in the evaluation of the phono-articulatory tract. MAGMA 9:5-15.
    • (1999) MAGMA , vol.9 , pp. 5-15
    • Meduri, S.1    Bazzocchi, M.2    Zuiani, C.3


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