Relative precision of inhaler aerodynamic particle size distribution (APSD) metrics by full resolution and abbreviated Andersen cascade impactors (ACIs): Part 2-investigation of bias in extra-fine mass fraction with AIM-HRT impactor

AAPS PharmSciTech

Volumn 11, Issue 3, 2010, Pages 1115-1118

  Mitchell, Jolyon P ^a   Nagel, Mark W ^a   Doyle, Cathy C ^a   Ali, Rubina S ^a   Avvakoumova, Valentina I ^a   Christopher, J David ^b   Quiroz, Jorge ^b   Strickland, Helen ^c   Tougas, Terrence ^d   Lyapustina, Svetlana ^e  

^a TRUDELL MEDICAL INTERNATIONAL   (Canada)

^b MERCK RESEARCH LABORATORIES   (United States)

^c GLAXOSMITHKLINE   (United States)

^d BOEHRINGER INGELHEIM PHARMACEUTICALS INC   (United States)

^e Drinker Biddle and Reath   (United States)

Author keywords

AIM HRT; impactor; inhaler; measurement bias; plate coating

Indexed keywords

ACCURACY; AMBIENT AIR; ARTICLE; DRUG FORMULATION; METERED DOSE INHALER; MICROSCOPY; PARTICLE SIZE; PRIORITY JOURNAL; RESPIRATORY SYSTEM;

ADMINISTRATION, INHALATION; AEROSOLS; DRUG COMPOUNDING; DRY POWDER INHALERS; EQUIPMENT DESIGN; EQUIPMENT FAILURE ANALYSIS; HUMANS; MATERIALS TESTING; PARTICLE SIZE; RESPIRATORY SYSTEM AGENTS; TECHNOLOGY, PHARMACEUTICAL;

EID: 78649933012     PISSN: None     EISSN: 15309932     Source Type: Journal    
DOI: 10.1208/s12249-010-9473-1     Document Type: Article

References (16)

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