Toll-like Receptor 10 in Helicobacter pylori Infection

Journal of Infectious Diseases

Volumn 212, Issue 10, 2015, Pages 1666-1676

  Nagashima, Hiroyuki ^a,b   Iwatani, Shun ^a,b   Cruz, Modesto ^c,d   Abreu, José A Jiménez ^e   Uchida, Tomohisa ^a   Mahachai, Varocha ^f   Vilaichone, Ratha Korn ^g   Graham, David Y ^b   Yamaoka, Yoshio ^a,b  

^a OITA UNIVERSITY   (Japan)

^b MICHAEL E DEBAKEY VETERANS AFFAIRS MEDICAL CENTER   (United States)

^c Universidad Autónoma de Santo Domingo   (Dominican Republic)

^d UNIVERSIDAD TECNOLÓGICA DE SANTIAGO   (Dominican Republic)

^e Dominican Japanese Digestive Disease Center Dr Luis E Aybar Health and Hygiene City   (Dominican Republic)

^f THAMMASAT UNIVERSITY HOSPITAL   (Thailand)

^g Bangkok Hospital Medical Center   (Thailand)

Author keywords

H. pylori LPS; Helicobacter pylori; Innate immunity; TLR10; TLR2 TLR10 heterodimer

Indexed keywords

BACTERIUM LIPOPOLYSACCHARIDE; HETERODIMER; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; MESSENGER RNA; TOLL LIKE RECEPTOR 10; TOLL LIKE RECEPTOR 2; LIPOPOLYSACCHARIDE; TLR10 PROTEIN, HUMAN;

ARTICLE; CONTROLLED STUDY; HELICOBACTER INFECTION; HELICOBACTER PYLORI; HUMAN; HUMAN CELL; HUMAN TISSUE; IMMUNOHISTOCHEMISTRY; INNATE IMMUNITY; MICROARRAY ANALYSIS; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; REAL TIME POLYMERASE CHAIN REACTION; STOMACH BIOPSY; TLR10 GENE; TLR2 GENE; UPREGULATION; CELL LINE; CHEMISTRY; COCULTURE; EPITHELIUM CELL; GENE EXPRESSION PROFILING; GENETICS; IMMUNOLOGY; METABOLISM; PATHOLOGY; STOMACH MUCOSA;

CELL LINE; COCULTURE TECHNIQUES; EPITHELIAL CELLS; GASTRIC MUCOSA; GENE EXPRESSION PROFILING; HELICOBACTER INFECTIONS; HELICOBACTER PYLORI; HUMANS; IMMUNOHISTOCHEMISTRY; LIPOPOLYSACCHARIDES; MICROARRAY ANALYSIS; NF-KAPPA B; REAL-TIME POLYMERASE CHAIN REACTION; TOLL-LIKE RECEPTOR 10; UP-REGULATION;

EID: 84949088170     PISSN: 00221899     EISSN: 15376613     Source Type: Journal    
DOI: 10.1093/infdis/jiv270     Document Type: Article

References (43)

1. Suerbaum S, Michetti P. Helicobacter pylori infection. N Engl J Med 2002; 347:1175-86.
2. Peterson WL. Helicobacter pylori and peptic ulcer disease. N Engl J Med 1991; 324:1043-8.
3. Uemura N, Okamoto S, Yamamoto S, et al. Helicobacter pylori infection and the development of gastric cancer. N Engl J Med 2001; 345:784-9.
4. Yamaoka Y. Mechanisms of disease: Helicobacter pylori virulence factors. Nat Rev Gastroenterol Hepatol 2010; 7:629-41.
5. Yamaoka Y, Yamauchi K, Ota H, et al. Natural history of gastric mucosal cytokine expression in Helicobacter pylori gastritis in Mongolian gerbils. Infect Immun 2005; 73:2205-12.
6. Akira S, Uematsu S, Takeuchi O. Pathogen recognition and innate immunity. Cell 2006; 124:783-801.
7. Patel MK, Trombly MI, Kurt-Jones EA. Innate immune responses to Helicobacter pylori infection: an overview. Methods Mol Biol 2012; 921:205-7.
8. Salama NR, Hartung ML, Muller A. Life in the human stomach: persistence strategies of the bacterial pathogen Helicobacter pylori. Nat Rev Microbiol 2013; 11:385-99.
9. Cullen TW, Giles DK, Wolf LN, Ecobichon C, Boneca IG, Trent MS. Helicobacter pylori versus the host: remodeling of the bacterial outer membrane is required for survival in the gastric mucosa. PLoS Pathog 2011; 7:e1002454.
10. Ferrero RL. Innate immune recognition of the extracellular mucosal pathogen, Helicobacter pylori. Mol Immunol 2005; 42:879-85.
11. Moran AP, Lindner B, Walsh EJ. Structural characterization of the lipid A component of Helicobacter pylori rough- and smooth-form lipopolysaccharides. J Bacteriol 1997; 179:6453-63.
12. Andersen-Nissen E, Smith KD, Strobe KL, et al. Evasion of Toll-like receptor 5 by flagellated bacteria. Proc Natl Acad Sci U S A 2005; 102:9247-52.
13. Smith MF Jr, Mitchell A, Li G, et al. Toll-like receptor (TLR) 2 and TLR5, but not TLR4, are required for Helicobacter pylori-induced NF-kappa B activation and chemokine expression by epithelial cells. J Biol Chem 2003; 278:32552-60.
14. Smith SM, Moran AP, Duggan SP, et al. Tribbles 3: a novel regulator of TLR2-mediated signaling in response to Helicobacter pylori lipopolysaccharide. J Immunol 2011; 186:2462-71.
15. Mayerle J, den Hoed CM, Schurmann C, et al. Identification of genetic loci associated with Helicobacter pylori serologic status. JAMA 2013; 309:1912-20.
16. Misch EA, Verbon A, Prins JM, Skerrett SJ, Hawn TR. A TLR6 polymorphism is associated with increased risk of Legionnaires' disease. Genes Immun 2013; 14:420-6.
17. Johnson CM, Lyle EA, Omueti KO, et al. Cutting edge: A common polymorphism impairs cell surface trafficking and functional responses of TLR1 but protects against leprosy. J Immunol 2007; 178:7520-4.
18. Shiota S, Cruz M, Jimenez Abreu JA, et al. Virulence genes of Helicobacter pylori in the Dominican Republic. J Med Microbiol 2014; 63:1189-96.
19. Shiota S, Mahachai V, Vilaichone RK, et al. Seroprevalence of Helicobacter pylori infection and gastric mucosal atrophy in Bhutan, a country with a high prevalence of gastric cancer. J Med Microbiol 2013; 62:1571-8.
20. Vilaichone RK, Mahachai V, Shiota S, et al. Extremely high prevalence of Helicobacter pylori infection in Bhutan. World J Gastroenterol 2013; 19:2806-10.
21. Matsunari O, Shiota S, Suzuki R, et al. Association between Helicobacter pylori virulence factors and gastroduodenal diseases in Okinawa, Japan. J Clin Microbiol 2012; 50:876-83.
22. Yamaoka Y, Osato MS, Sepulveda AR, et al. Molecular epidemiology of Helicobacter pylori: separation of H. pylori from East Asian and non- Asian countries. Epidemiol Infect 2000; 124:91-6.
23. Akopyants NS, Clifton SW, Kersulyte D, et al. Analyses of the cag pathogenicity island of Helicobacter pylori. Mol Microbiol 1998; 28:37-53.
24. Dixon MF, Genta RM, Yardley JH, Correa P. Classification and grading of gastritis. The updated Sydney System. InternationalWorkshop on the Histopathology of Gastritis, Houston 1994. Am J Surg Pathol 1996; 20:1161-81.
25. Uchida T, Kanada R, Tsukamoto Y, et al. Immunohistochemical diagnosis of the cagA-gene genotype of Helicobacter pylori with anti-East Asian CagA-specific antibody. Cancer Sci 2007; 98:521-8.
26. Chailler P, Menard D. Establishment of human gastric epithelial (HGE) cell lines exhibiting barrier function, progenitor, and prezymogenic characteristics. J Cell Physiol 2005; 202:263-74.
27. Fiorentino M, Ding H, Blanchard TG, Czinn SJ, Sztein MB, Fasano A. Helicobacter pylori-induced disruption of monolayer permeability and proinflammatory cytokine secretion in polarized human gastric epithelial cells. Infect Immun 2013; 81:876-83.
28. Buwitt-Beckmann U, Heine H, Wiesmuller KH, et al. TLR1- and TLR6- independent recognition of bacterial lipopeptides. J Biol Chem 2006; 281:9049-57.
29. Regan T, Nally K, Carmody R, et al. Identification of TLR10 as a key mediator of the inflammatory response to Listeria monocytogenes in intestinal epithelial cells and macrophages. J Immunol 2013; 191:6084-92.
30. Guan Y, Ranoa DR, Jiang S, et al. Human TLRs 10 and 1 share common mechanisms of innate immune sensing but not signaling. J Immunol 2010; 184:5094-103.
31. Govindaraj RG, Manavalan B, Lee G, Choi S. Molecular modelingbased evaluation of hTLR10 and identification of potential ligands in Toll-like receptor signaling. PLoS One 2010; 5:e12713.
32. Medzhitov R, Preston-Hurlburt P, Janeway CA Jr. A human homologue of the Drosophila Toll protein signals activation of adaptive immunity. Nature 1997; 388:394-7.
33. Chuang T, Ulevitch RJ. Identification of hTLR10: a novel human Tolllike receptor preferentially expressed in immune cells. Biochim Biophys Acta 2001; 1518:157-61.
34. Lee SM, Kok KH, Jaume M, et al. Toll-like receptor 10 is involved in induction of innate immune responses to influenza virus infection. Proc Natl Acad Sci U S A 2014; 111:3793-8.
35. Kumar Pachathundikandi S, Brandt S, Madassery J, Backert S. Induction of TLR-2 and TLR-5 expression by Helicobacter pylori switches cagPAI-dependent signalling leading to the secretion of IL-8 and TNF-alpha. PLoS One 2011; 6:e19614.
36. Shuto T, Imasato A, Jono H, et al. Glucocorticoids synergistically enhance nontypeable Haemophilus influenzae-induced Toll-like receptor 2 expression via a negative cross-talk with p38 MAP kinase. J Biol Chem 2002; 277:17263-70.
37. Melmed G, Thomas LS, Lee N, et al. Human intestinal epithelial cells are broadly unresponsive to Toll-like receptor 2-dependent bacterial ligands: implications for host-microbial interactions in the gut. J Immunol 2003; 170:1406-15.
38. Uddin MJ, Nuro-Gyina PK, Islam MA, et al. Expression dynamics of Toll-like receptors mRNA and cytokines in porcine peripheral blood mononuclear cells stimulated by bacterial lipopolysaccharide. Vet Immunol Immunopathol 2012; 147:211-22.
39. Kawai T, Akira S. Toll-like receptors and their crosstalk with other innate receptors in infection and immunity. Immunity 2011; 34:637-50.
40. Needham BD, Trent MS. Fortifying the barrier: the impact of lipid A remodelling on bacterial pathogenesis. Nat Rev Microbiol 2013; 11:467-81.
41. Suda Y, Ogawa T, KashiharaW, et al. Chemical structure of lipid A from Helicobacter pylori strain 206-1 lipopolysaccharide. J Biochem 1997; 121:1129-33.
42. Suda Y, Kim YM, Ogawa T, et al. Chemical structure and biological activity of a lipid A component from Helicobacter pylori strain 206. J Endotoxin Res 2001; 7:95-104.
43. Quintana-Murci L, Clark AG. Population genetic tools for dissecting innate immunity in humans. Nat Rev Immunol 2013; 13:280-93.