Induction of TLR-2 and TLR-5 expression by helicobacter pylori switches cagPAI-dependent signalling leading to the secretion of IL-8 and TNF-α

PLoS ONE

Volumn 6, Issue 5, 2011, Pages

  Kumar Pachathundikandi, Suneesh ^a,b   Brandt, Sabine ^a   Madassery, Joseph ^b   Backert, Steffen ^a,c  

^a OTTO VON GUERICKE UNIVERSITY   (Germany)

^b UNIVERSITY OF CALICUT   (India)

^c UNIVERSITY COLLEGE DUBLIN   (Ireland)

Author keywords

[No Author keywords available]

Indexed keywords

CAGA PROTEIN; I KAPPA B; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; INTERLEUKIN 1 RECEPTOR ASSOCIATED KINASE 1; INTERLEUKIN 8; LUCIFERASE; SYNAPTOTAGMIN I; TOLL LIKE RECEPTOR 2; TOLL LIKE RECEPTOR 5; TUMOR NECROSIS FACTOR ALPHA;

ANTIBODY SPECIFICITY; ARTICLE; CONTROLLED STUDY; CYTOKINE RELEASE; CYTOPLASM; EMBRYO; ENZYME ASSAY; GENE SWITCHING; HELICOBACTER PYLORI; HUMAN; HUMAN CELL; INNATE IMMUNITY; NONHUMAN; PATHOGENICITY ISLAND; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN PHOSPHORYLATION; QUALITATIVE ANALYSIS; SIGNAL TRANSDUCTION; TYPE IV SECRETION SYSTEM; WILD TYPE;

ANTIGENS, BACTERIAL; BACTERIAL PROTEINS; CELL LINE; GENOMIC ISLANDS; HEK293 CELLS; HELICOBACTER INFECTIONS; HELICOBACTER PYLORI; HUMANS; I-KAPPA B PROTEINS; INFLAMMATION MEDIATORS; INTERLEUKIN-1 RECEPTOR-ASSOCIATED KINASES; INTERLEUKIN-8; NF-KAPPA B; PHOSPHORYLATION; PHOSPHOSERINE; RNA, MESSENGER; SIGNAL TRANSDUCTION; TOLL-LIKE RECEPTOR 2; TOLL-LIKE RECEPTOR 5; TRANSCRIPTION FACTOR AP-1; TRANSCRIPTIONAL ACTIVATION; TUMOR NECROSIS FACTOR-ALPHA; UP-REGULATION;

HELICOBACTER PYLORI;

EID: 79955811321     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0019614     Document Type: Article

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