Classification and grading of Gastritis: The updated Sydney system

American Journal of Surgical Pathology

Volumn 20, Issue 10, 1996, Pages 1161-1181

  Dixon, Michael F ^a   Genta, Robert M ^b,f   Yardley, John H ^c   Correa, Pelayo ^d   Batts, Kenneth P ^e   Dahms, Beverly B ^e   Filipe, M Isabel ^e   Haggitt, Rodger C ^e   Haot, Jules ^e   Hui, P K ^e   Lechago, Juan ^e   Lewin, Klaus ^e   Offerhaus, Johan A ^e   Price, Ashley B ^e   Recavarren, Sixto ^e   Riddell, Robert H ^e   Sipponen, Pentti ^e   Solcia, Enrico ^e   Stolte, Manfred ^e   Watanabe, Hidenobu ^e  

^a UNIVERSITY OF LEEDS   (United Kingdom)

^b BAYLOR COLLEGE OF MEDICINE   (United States)

^c JOHNS HOPKINS UNIVERSITY SCHOOL OF MEDICINE   (United States)

^d LOUISIANA STATE UNIV MEDICAL CENTER   (United States)

^e VAMC ^*

^f MICHAEL E DEBAKEY VETERANS AFFAIRS MEDICAL CENTER   (United States)

Author keywords

Classification; Diagnosis; Gastritis; Gastroenterology; Sydney System; Terminology

Indexed keywords

ARTICLE; DISEASE CLASSIFICATION; EOSINOPHILIC GASTRITIS; GASTRITIS; HELICOBACTER PYLORI; HISTOPATHOLOGY; HUMAN; INFECTION; MORPHOLOGY; PROGNOSIS; RADIATION INJURY; STAINING; STOMACH BIOPSY; TOPOGRAPHY; VASCULAR DISEASE;

EID: 0013575179     PISSN: 01475185     EISSN: None     Source Type: Journal    
DOI: 10.1097/00000478-199610000-00001     Document Type: Article

References (118)

1. Andrew A, Wyatt JI, Dixon MF. Observer variation in the assessment of chronic gastritis according to the Sydney system. Histopathology 1994;25:317-22.
2. Appelman HD. Gastritis: terminology, etiology, and clinicopathological correlations: another biased view. Hum Pathol 1994;25:1006-19.
3. Arnold R, Hulst MV, Neuhof CH, Schwarting H, Becker HD, Creutzfeldt W. Antral gastrin-producing G-cells and somatostatin-producing D-cells in different states of gastric acid secretion. Gut 1982;23:285-91.
4. Bayerdörffer E, Oertel H. Lehn N, et al. Topographic association between active gastritis and Campylobacter pylori colonisation. J Clin Pathol 1989;42:834-9.
5. Bigotti G, Coli A. Gastric syphilis simulating malignant lymphoma. Pathologica 1991;83:217-22.
6. Bohrod MG. What is a pathologic diagnosis? A prelude to computer diagnosis. Pathol Annu 1971;6:197-208.
7. Carpenter HA, Talley NJ. Gastroscopy is incomplete without biopsy: clinical relevance of distinguishing gastropathy from gastritis. Gastroenterology 1995;108:917-24.
8. Cartun RW, Kryzmowski GA, Pedersen CA, Morin SG, Van Kruiningen HJ, Berman MM. Immunocytochemical identification of Helicobacter pylori in formalin-fixed gastric biopsies. Mod Pathol 1991;4:498-502.
9. Cattan D, Roucayrol AM, Launay JM, et al. Circulating gastrin, endocrine cells, histamine content, and histidine decarboxylase activity in atrophic gastritis. Gastroenterology 1989;97:586-96.
10. Cersosimo E, Wilkowske CJ, Rosenblatt JE, Ludwig J. Isolated antral narrowing associated with gastrointestinal cryptosporidiosis in acquired immunodeficiency syndrome. Mayo Clin Proc 1992;67:553-6.
11. Chan MF, Friedman SL. Gastritis and abdominal pain in HIV-infected patients. In: Blaser MJ, Smith PD, Ravdin JI, Greenberg HB, Guerrant RL. eds: Infections of the gastrointestinal tract. New York: Raven Press, 1995:471-82.
12. Chan WY, Hui PK, Leung KM, Chow J, Kwok F, Ng CS. Coccoid forms of Helicobacter pylori in the human stomach. Am J Clin Pathol 1994;102:503-7.
13. Colletti RB, Trainer TD. Collagenous gastritis. Gustroenterology 1989;97:1552-5.
14. Correa P. Human gastric carcinogenesis: a multistep and multifactorial process - First American Cancer Society Award Lecture on Cancer Epidemiology and Prevention. Cancer Res 1992;52:6735-40.
15. Correa P, Shiao YH. Phenotypic and genotypic events in gastric carcinogenesis. Cancer Res 1994;54:1941s-1943s.
16. Cosset JM, Henry-Amar M, Burgers JM, et al. Late radiation injuries of the gastrointestinal tract in the H2 and H5 EORTC Hodgkin's disease trials: emphasis on the role of exploratory laparotomy and fractionation. Radiother Oncol 1988;13:61-8.
17. Cruz FO, Soffia PS, Del Rio PM, Fava MP, Duarte IG. Acute phlegmonous gastritis with mural abscess: CT diagnosis. Am J Roentgenol 1992;159:767-8.
18. Davies GR, Banatvala N, Collins CE, et al. Relationship between infective load of Helicobacter pylori and reactive oxygen metabolite production in antral mucosa. Scand J Gastroenterol 1994;29:419-24.
19. Day DW, Dixon MF. Biopsy pathology of the oesophagus, stomach and duodenum. London: Chapman & Hall Medical, 1995:156.
20. De Giacomo C, Gianatti A, Negrini R, et al. Lymphocytic gastritis: a positive relationship with celiac disease. J Pediatr 1994;124:57-62.
21. DeLuca VA, Jr. Helicobacter pylori gastric atrophy and pernicious anemia. Gastroenterology 1992;102:744-5.
22. Dempsey PJ, Goldenring JR, Soroka CJ, et al. Possible role of transforming growth factor alpha in the pathogenesis of Menetrier's disease: supportive evidence form humans and transgenic mice. Gastroenterology 1992;103:1950-63.
23. Dixon MF, Wyatt JI, Burke DA, Rathbone BJ. Lymphocytic gastritis - relationship to Campylobacter pylori infection. J Pathol 1988;154:125-32.
24. Doglioni C, De Boni M, Cielo R, et al. Gastric giardiasis. J Clin Pathol 1992;45:964-7.
25. Doglioni C, Laurino L, Dei Tos AP, et al. Pancreatic (acinar) metaplasia of the gastric mucosa: histology, ultrastructure, immunocytochemistry. and clinicopathologic correlations of 101 cases. Am J Surg Pathol 1993;17:1134-43.
26. Ectors N, Geboes K, Wynants P, Desmet V. Granulomatous gastritis and Whipple's disease. Am J Gastroenterol 1992;87:509-13.
27. Ectors NL, Dixon MF, Geboes KJ, Rutgeerts PJ, Desmet VJ, Vantrappen GR. Granulomatous gastritis: a morphological and diagnostic approach. Histopathology 1993;23:55-61.
28. el-Zimaity HM, Graham DY, al-Assi MT, et al. Interobserver variation in the histopathological assessment of Helicobacter pylori gastritis. Hum Pathol 1996;27:35-41.
29. Filipe MI, Munoz N, Matko I, et al. Intestinal metaplasia types and the risk of gastric cancer: a cohort study in Slovenia. Int J Cancer 1994;57:324-9.
30. Fiocca R, Luinetti O, Villani L, Chiaravalli AM, Capella C, Solcia E. Epithelial cytotoxicity, immune responses, and inflammatory components of Helicobacter pylori gastritis. Scand J Gastroenterol Suppl 1994;205:11-21.
31. Fiocca R, Villani L, Luinetti O, et al. Helicobacter colinization and histopathological profile of chronic gastritis in patients with or without dyspepsia, mucosal erosion and peptic ulcer: a morphological approach to the study of ulcerogenesis in man. Virchows Arch A Pathol Anat Histopathol 1992;420:489-98.
32. Fléjou JF, Bahame P, Smith AC, Stockbrugger RW, Rode J, Price AB. Pernicious anaemia and Campylobacter like organisms; is the gastric antrum resistant to colonisation? Gut 1989;30:60-4.
33. Fraser AG, Koelmeyer T, White AC, Nicholson GI. Antral vascular ectasia: the watermelon stomach. N Z Med J 1992; 105:338-9.
34. Fukao A, Komatsu S, Tsubono Y, et al. Helicohacter pylori infection and chronic atrophic gastritis among Japanese blood donors: a cross-sectional study. Cancer Causes Control 1993;4:307-12.
35. Genta RM, Caymmi-Gomes M. Pathology. In: Grove DI. ed. Strongyloidiasis: a major roundworm infection of man. London: Taylor & Francis. 1989:105-32.
36. Genta RM, Graham DY. Comparison of biopsy sites for the histopathologic diagnosis of Helicobacter pylori: a topographic study of Helicobacter pylori density and distribution. Gastrointest Endosc 1994;40:342-5.
37. Genta RM, Hamner HW. The significance of lymphoid follicles in the interpretation of gastric biopsy specimens. Arch Pathol Lab Med 1994;118:740-3.
38. Genta RM, Hamner HW, Graham DY. Gastric lymphoid follicles in Helicobater pylori infection: frequency, distribution, and response to triple therapy. Hum Pathol 1993; 24:577-83.
39. Genta RM, Lew GM, Graham DY. Changes in the gastric mucosa following eradication of Helicobacter pylori. Mod Pathol 1993;6:281-9.
40. Genta RM, Robason GO, Graham DY. Simultaneous visualization of Helicobacter pylori and gastric morphology: a new stain. Hum Pathol 1994;25:221-6.
41. Goldgraber MB, Rubin CE, Palmer WL, Dobson RL, Massey BW. The early gastric response to irradiation, a serial biopsy study. Gastroenterology 1954;27:1-20.
42. Goldman H, Proujansky R. Allergic proctitts and gastroenteritis in children: clinical and mucosal biopsy features in 53 cases. Am J Surg Pathol 1986;10:75-86.
43. Goodgame RW, Genta RM, Go MF, Graham DY. Infectious gastritis. In: Surawicz C, Owen RL, eds. Gastrointestinal and hepatic infections. Philadelphia: WB Saunders Company, 1995:47-74.
44. Gostout CJ, Viggiano TR, Ahlquist DA, Wang KK, Larson MV, Balm R. The clinical and endoscopic spectrum of the watermelon stomach. J Clin Gastroenterol 1992;15:256-63.
45. Graham DY, Genta RM. Reinfection with Helicobacter pylori. In: Hunt RH, Tytgat GNJ, eds. Helicobacter pylori: basic mechanisms to clinical cure. Dordrescht: Kluwer Academic Publishers, 1994:113-20.
46. Green DM, Bishop AE, Rindi G, et al. Enterochromaffin-like cell populations in human fundic mucosa: quantitative studies of their variations with age, sex, and plasma gastrin levels. J Pathol 1989;157:235-41.
47. Greenstein DB, Wilcox CM, Schwartz DA. Gastric syphilis: report of seven cases and review of the literature. J Clin Gastroenterol 1994;18:4-9.
48. Guarino M, Reale D, Micoli G, Tricomi P, Cristofori E. Xanthogranulomatous gastritis: association with xanthogramulomatous cholecystitis [see Comments]. J Clin Pathol 1993;46:88-90.
49. Haggitt RC. Granulomatous diseases of the gastrointestinal tract. In: Ioachim HL, ed. Pathology of gramulomas. New York: Raven Press, 1983:257-305.
50. Haot J, Berger F, Andre C, Moulinier B, Mainguet P, Lambert R. Lymphocytic gastritis versus varioliform gastritis: a historical series revisited. J Pathol 1989;158:19-22.
51. Haot J, Hamichi L, Wallez L, Mainguet P. Lymphocytic gastritis: a newly described entity: a retrospective endoscopic and histological study. Gut 1988;29:1258-64.
52. Havu N, Maaroos HI, Sipponen P. Argyrophil cell hyperplasia associated with chronic corpus gastritis in gastric ulcer disease. Scand J Gastroenterol Suppl 1991;186:90-4.
53. Hui PK, Chan WY, Cheung PS, Chan JK, Ng CS. Pathologic changes of gastric mucosa colonized by Helicobacter pylori. Hum Pathol 1992;23:548-56.
54. Hunt RH. Hp and pH: implications for the eradication of Helicobacter pylori. Scand J Gastroenterol Suppl 1993; 196:12-6.
55. Ikeda K, Kumashiro R, Kifune T. Nine cases of acute gastric anisakiasis. Gastrointest Endosc 1989;35:304-8.
56. Isaacson PG. Gastrointestinal lymphoma. Hum Pathol 1994;25:1020-9.
57. Jass JR, Filipe MI. The mucin profiles of normal gastric mucosa, intestinal metaplasia and its variants and gastric carcinoma. Histochem J 1981;13:931-9.
58. Karnes WE Jr, Samloff IM, Siurala M, Kekki M, Sipponen P, Kim SW, Walsh JH. Positive serum antibody and negative tissue staining for Helicobacter pylori in subjects with atrophic body gastritis. Gastroenterology 1991;101:167-74.
59. Kasmin F, Reddy S, Mathur-Wagh U, et al. Syphilitic gastritis in an HIV-infected individual. Am J Gastroenterol 1992;87:1820-2.
60. Kazi JI, Alam SM, Khan AA, Ara J. Eosionphilic gastritis. J Pak Med Assoc 1987;37:9-13.
61. Kovacs AA, Churchill MA, Wood D, Mascola L, Zaia JA. Molecular and epidemiologic evaluations of a cluster of cases of Menetrier's disease associated with cytomegalovirus. Pediatr Infect Dis J 1993;12:1011-4.
62. Kraus J, Schneider R. Pernicious anemia caused by Crohn's disease of the stomach. Am J Gastroenterol 1979; 71:202-5.
63. Laine L, Cominelli F, Sloane R, Casini-Raggi V, Marin-Sorensen M, Weinstein WM. Interaction of NSAIDs and Helicobacter pylori on gastrointestinal injury and prostaglandin production: a controlled double-blind trial. Aliment Pharmacol Ther 1995;9:127-35.
64. Laine L, Weinstein WM. Subepithelial hemorrhages and erosions of human stomach. Dig Dis Sci 1988;33:490-503.
65. Laine L, Weinstein WM. Histology of alcoholic hemorrhagic "gastritis": a prospective evaluation. Gastroenterology 1988;94:1254-62.
66. Lee A, O'Rourke J, Kellow JE. Gastrospirillum hominis (Helicobacter heilmannii) and other gastric infections of humans. In: Blaser MJ, Smith PD, Ravdin JI, Greenberg HB, Guerrant RL, eds. Infections of the gastrointestinal tract. New York: Raven Press, 1995:589-601.
67. Leung KM, Hui PK, Chan WY, Thomas TM, Helicobacter pylori-related gastritis and gastric ulcer: a continuum of progressive epithelial degeneration. Am J Clin Pathol 1992; 98:569-74.
68. Masuda R, Toyoshima H, Bandou T, Isoyama T, Matsui Y, Takemura T. Malignant lymphoma of the stomach associated with systemic sarcoidosis. Cancer 1992;70:2592-6.
69. McGovern TW, Talley NJ, Kephart GM, Carpenter HA, Gleich GJ. Eosinophil infiltration and degranulation in Helicobacter pylori-associated chronic gastritis. Dig Dis Sci 1991;36:435-40.
70. Misiewicz JJ. The Sydney System: a new classification of gastritis. Introduction. J Gastroenterol Hepatol 1991;6:207-8.
71. Mitchell JD, Mitchell HM, Tobias V. Acute Helicobacter pylori infection in an infant, associated with gastric ulceration and serological evidence of intra-familial transmission. Am J Gastroenterol 1992;87:382-6.
72. Mosnier JF, Fléjou JF, Amouyal G, et al. Hypertrophic gastropathy with gastric adenocarcinoma: Menetrier's disease and lymphocytic gastritis? Gut 1991;32:1565-7.
73. O'Donovan C, Murray J, Staunton H, Doyle JS, Leader M. Granulomatous gastritis: part of a vasculitic syndrome. Hum Pathol 1991;22:1057-9.
74. Offerhaus GJ, Rieu PN, Jansen JB, Joosten HJ, Lamers CB. Prospective comparative study of the influence of postoperative bile reflux on gastric mucosal histology and Campylobacter pylori infection. Gut 1989;30:1552-7.
75. Offerhaus GJ, van de Stadt J, Huibregtse K, Tersmette AC, Tytgat GN. The mucosa of the gastric remnant harboring malignancy. Histologic findings in the biopsy specimens of 504 asymptomatic patients 15 to 46 years after partial gastrectomy with emphasis on nonmalignant lesions. Cancer 1989;64:698-703.
76. Oren R, Harats N, Polak A, Libson E, Naparstek Y. Granulomatous colitis 10 years after presentation with isolated Crohn's gastritis. Am J Gastroenterol 1989;84:449-50.
77. Payen JL, Cales P, Voigt JJ, et al. Severe portal hypertensive gastropathy and antral vascular ectasia are distinct entities in patients with cirrhosis. Gastroenterology 1995;108:138-44.
78. Price AB. The Syndey System: histological division. J Gastroenterol Hepatol 1991;6:209-22.
79. Quinn CM, Bjarnason I, Price AB. Gastritis in patients on non-steroidal anti-inflammatory drugs. Histopathology 1993;23:341-8.
80. Rocha GA, Queiroz DM, Mendes EN, Barbosa AJ, Lima Junior GF, Oliveira CA. Helicobacter pylori acute gastritis: histological, endoscopical, clinical, and therapeutic features. Am J Gastroenterol 1991;86:1592-5.
81. Rokkas T, Filipe MI, Sladen GE. Detection of an increased incidence of early gastric cancer in patients with intestinal metaplasia type III who are closely followed up. Gut 1991; 32:1110-3.
82. Rugge M, Farinati F, Baffa R, et al. Gastric epithelial dysplasia in the natural history of gastric cancer: a multicenter prospective follow-up study. Interdisciplinary Group on Gastric Epithelial Dysplasia. Gastroenterology 1994;107:1288-96.
83. Rugge M, Farinati F, Di Mario F, Baffa R, Valiante F, Cardin F. Gastric epithelial dysplasia: a prospective multicenter follow-up study from the Interdisciplinary Group on Gastric Epithelial Dysplasia. Hum Pathol 1991;22:1002-8.
84. Sacco D, Bardella R, Spidalieri G, Cardino L. Acute abdomen caused by eosinophilic gastritis. Minerva Chir 1994; 49:867-8.
85. Shuster LD, Cox G, Bhatia P, Miner PB Jr. Gastric mucosal nodules due to cytomegalovirus infection. Dig Dis Sci 1989;34:103-7.
86. Sinzger C, Plachter B, Stenglein S, Jahn G. Immunohistochemical detection of viral antigens in smooth muscle, stromal, and epithelial cells from acute human cytomegalovirus gastritis. J Infect Dis 1993;167:1427-32.
87. Sipponen P. Gastric cancer - a long-term consequence of Helicobacter pylori infection? Scand J Gastroemerol Suppl 1994;201:24-27.
88. Sipponen PH. Role of Helicobacter pylori in the pathogenesis of gastritis, peptic ulcer and gastric cancer. Scand J Gastroenterol Suppl 1993;196:3-6.
89. Sipponen P, Kosunen TU, Valle J, Riihelä M, Seppälä K. Helicobacter pylori infection and chronic gastritis in gastric cancer. J Clin Pathol 1992;45:319-23.
90. Sipponen P, Riihelä M, Hyvärinen H, Seppälä K. Chronic nonatrophic ('superficial') gastritis increases the risk of gastric carcinoma: a case-control study. Scand J Gastro-enterol 1994;29:336-40.
91. Sobala GM, Crabtree JE, Dixon MF, et al. Acute Helicobacter pylori infection, clinical features, local and systemic immune response, gastric mucosal histology, and gastric juice abscorbic acid concentrations. Gut 1991;32:1415-8.
92. Sobala GM, King RF, Axon AT, Dixon MF. Reflux gastritis in the intact stomach. J Clin Pathol 1990;43:303-6.
93. Sobala GM, O'Connor HJ, Dewar EP, King RF, Axon AT, Dixon MF. Bile reflux and intestinal metaplasia in gastric mucosa. J Clin Pathol 1993;46:235-40.
94. Solcia E, Capella C, Fiocca R, et al. Exocrine and endocrine epithelial changes in types A and B chronic gastritis. In: Malfertheiner P, Ditschuneit H, eds. Helicobacter pylori, gastritis, and peptic ulcer. Berlin: Springer Verlag, 1990:245-58.
95. Solcia E, Fiocca R, Villani L, et al. Morphology and pathogenesis of endocrine hyperplasias. precarcinoid lesions, and carcinoids arising in chronic atrophic gastritis. Scand J Gastroenterol Suppl 1991;180:146-59.
96. Solcia E, Rindi G, Silini E, Villani L. Enterochromaffinlike (ECL) cells and their growths: relationships to gastrin, reduced acid secretion and gastritis. Baillieres Clin Gastroenterol 1993;7:149-65.
97. Solcia E, Villani L, Fiocca R, et al. Effects of eradication of Helicohacter pylori on gastritis in duodenal ulcer patients. Scand J Gastroenterol Suppl 1994;201:28-34.
98. Solcia E, Villani L, Luinetti O, Fiocca R. Proton pump inhibitors, enterochromaffin-like cell growth and Helicobacter pylori gastritis. Ailment Pharmacol Ther 1929; 7(suppl)1:25-8.
99. Stemmermann GN. Intestinal metaplasia of the stomach: a status report. Cancer 1994;74:556-64.
100. Stolte M, Bethke B, Ruhl G, Ritter M. Omeprazole-induced pseudohypertrophy of gastric parietal cells. Z Gastroenterol 1992;30:134-8.
101. Stolte M, Eidt S. Lymphoid follicles in antrat mucosa: immune response to Campylobacter pylori? J Clin Pathol 1989;42:1269-71.
102. Stolte M, Eidt S. Chronic erosions of the antral mucosa: a sequela of Helicobacter pylori-induced gastritis. Z Gastroenterol 1992;30:846-50.
103. Stolte M, Ritter M, Borchard F, Koch-Scherrer G. Collagenous gastroduodenitis on collagenous colitis. Endoscopy 1990;22:186-7.
104. Stolte M, Stadelmann O, Bethke B, Burkard G. Relationships between the degree of Helicobacter pylori colonisation and the degree of gastritis, surface epithelial degeneration and mucus secretion. Z Gastroenterol 1995;33:89-93.
105. Stolte M, Wellens E, Bethke B, Ritter M, Eidt H. Helicobacter heilmannii (formerly Gastrospirillum hominis) gastritis: an infection transmitted by animals? Scand J Gastroenterol 1994;29:1061-4.
106. Sugimura T, Sugano H, Terada M, Stemmermann GN, Yasui W, Tahara E. First International Workshop of the Princess Takamatsu Cancer Research Fund: intestinal metaplasia and gastric cancer. Mol Carcinog 1994;11:1-7.
107. Suit PF, Petras RE, Bauer TW, Petrini JL Jr. Gastric antral vascular ectasia: a histologic and morphometric study of "the watermelon stomach." Am J Surg Pathol 1987;11:750-7.
108. Tosi P, Filipe MI, Luzi P, et al. Gastric intestinal metaplasia type III cases are classified as low-grade dysplasia on the basis of morphometry. J Pathol 1993;169:73-8.
109. Trespi E, Broglia F, Villani L, Luinelti O, Fiocca R, Solcia E. Distinct profiles of gastritis in dyspepsia subgroups. Their different clinical responses to gastritis healing after Helicobacter pylori eradication. Scand J Gastroenterol 1994;29:884-8.
110. Tromba JL, Inglese R, Rieders B, Todaro R. Primary gastric tuberculosis presenting as pylori outlet obstruction. Am J Gastroenterol 1991;86:1820-2.
111. Varis K, Kekki M, Harkonen M, Sipponen P, Samloff IM. Serum pepsinogen I and serum gastrin in the screening of atrophic pangastritis with high risk of gastric cancer. Scand J Gastroenterol Suppl 1991;186:117-23.
112. Weissman D, Gumaste VV, Dave PB, Keh W. Bleeding from a tuberculous gastric ulcer. Am J Gastroenterol 1990; 85:742-4.
113. Witteman EM, Mravunac M, Becx MJ, et al. Improvement of gastric inflammation and resolution of epithelial damage one year after eradication of Helicobacter pylori. J Clin Pathol 1995;48:250-6.
114. Wolber R, Owen D, DelBuono L, Appelman H, Freeman H. Lymphocytic gastritis in patients with celiac sprue or spruelike intestinal disease. Gastroenterology 1990;98:310-5.
115. Wolfsen HC, Carpenter HA, Talley NJ, Menetrier's disease: a form of hypertrophic gastropathy or gastritis? Gastroenterology 1993;104:1310-9.
116. Wotherspoon AC, Ortiz-Hidalgo C, Falzon MR, Isaacson PG. Helicobacter pylori-associated gastritis and primary B-cell gastric lymphoma. Lancet 1991;338:1175-6.
117. Wyatt JI, Knight T, Wilson A, et al. Helicobacter pylori, gastritis and serum pepsinogen A in a male non-patient population [Abstract]. Gut 1995;37:A4.
118. Wyatt JI, Shallcross TM, Crabtree JE, Heatley RV. Helicobacter pylori, gastritis and peptic ulceration in the elderly. J Clin Pathol 1992;45:1070-4.