F-box protein 7 mutations promote protein aggregation in mitochondria and inhibit mitophagy

Human Molecular Genetics

Volumn 24, Issue 22, 2015, Pages 6314-6330

  Zhou, Zhi Dong ^a,b   Xie, Shao Ping ^a   Sathiyamoorthy, Sushmitha ^a   Saw, Wuan Ting ^a   Sing, Tan Ye ^a   Ng, Shin Hui ^a   Chua, Heidi Pek Hup ^a   Tang, Alyssa Mei Yan ^a   Shaffra, Fathima ^a   Li, Zeng ^a   Wang, Hongyan ^b   Ho, Patrick Ghim Hoe ^a   Lai, Mitchell Kim Peng ^c   Angeles, Dario C ^d   Lim, Tit Meng ^e   Tan, Eng King ^a,b,d  

^a NATIONAL NEUROSCIENCE INSTITUTE   (Singapore)

^b DUKE NUS MEDICAL SCHOOL   (Singapore)

^c NATIONAL UNIVERSITY OF SINGAPORE   (Singapore)

^d SINGAPORE GENERAL HOSPITAL   (Singapore)

^e NATIONAL UNIVERSITY OF SINGAPORE   (Singapore)

Author keywords

[No Author keywords available]

Indexed keywords

F BOX PROTEIN; F BOX PROTEIN 7; GLUTATHIONE; HEAT SHOCK PROTEIN; NEUROTOXIN; PROTEIN AGGREGATE; UBIDECARENONE; UNCLASSIFIED DRUG; FBXO7 PROTEIN, HUMAN; PARKIN; UBIQUITIN PROTEIN LIGASE;

AGGRESOME; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CELL VIABILITY; CELLULAR DISTRIBUTION; CONTROLLED STUDY; DOPAMINERGIC NERVE CELL; GENE MUTATION; MITOCHONDRION; MITOPHAGY; MOLECULAR GENETICS; MOUSE; NERVE CELL DEGENERATION; NONHUMAN; PARKINSON DISEASE; PRIORITY JOURNAL; PROTEIN AGGREGATION; PROTEIN EXPRESSION; TRANSGENIC DROSOPHILA; WESTERN BLOTTING; ANIMAL; CELL CULTURE; DROSOPHILA; FEMALE; GENETICS; HUMAN; METABOLISM; MUTATION; PARKINSONISM; PREGNANCY; TRANSGENIC MOUSE; UBIQUITINATION;

ANIMALS; CELLS, CULTURED; DROSOPHILA; F-BOX PROTEINS; FEMALE; HUMANS; MICE; MICE, TRANSGENIC; MITOCHONDRIA; MITOCHONDRIAL DEGRADATION; MUTATION; PARKINSONIAN DISORDERS; PREGNANCY; PROTEIN AGGREGATES; UBIQUITIN-PROTEIN LIGASES; UBIQUITINATION;

EID: 84949032530     PISSN: 09646906     EISSN: 14602083     Source Type: Journal    
DOI: 10.1093/hmg/ddv340     Document Type: Article

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