Tandem Mass Spectrometry and Polymer Ion Dissociation

MALDI Mass Spectrometry for Synthetic Polymer Analysis

Volumn 175, Issue , 2009, Pages 85-127

  Polce, Michael J ^a   Wesdemiotis, Chrys ^b  

^a Lubrizol Advanced Materials Inc   (United States)

^b UNIVERSITY OF AKRON   (United States)

Author keywords

MS MS instrumentation for polymer analysis; Polymer fragmentation mechanisms; Tandem mass spectrometry and polymer ion dissociation

Indexed keywords

DISSOCIATION; MASS SPECTROMETRY;

ION DISSOCIATIONS; POLYMER ANALYSIS; POLYMER FRAGMENTATIONS; TANDEM MASS SPECTROMETRY;

POLYMERS;

EID: 84948967576     PISSN: None     EISSN: None     Source Type: Book    
DOI: 10.1002/9780470567234.ch5     Document Type: Chapter

References (211)

1. Cowie, J.M.G., Polymers: Chemistry & Physics of Modern Materials. 2nd edition. London: Blackie Academic & Professional, 1991.
2. Kennedy, J.P.; Iván, B., Designed Polymers by Carbocationic Macromolecular Engineering. Munich: Hanser Publishers, 1992.
3. Hsieh, H.L.; Quirk, R.P., Anionic Polymerization: Principles and Practical Applications. New York: Marcel Dekker, 1996.
4. Carraher, C.E., Jr., Seymour/Carraher ' s Polymer Chemistry. 5th edition. New York: Marcel Dekker, 2000.
5. Rodriguez, F.; Cohen, C.; Ober, C.; Archer, L.A., Principles of Polymer Systems. 5th edition. New York: Taylor & Francis, 2003.
6. Sheng, L.-S.; Shew, S.L.; Winger, B.E.; Campana, J.E., A new generation of mass spectrometry for characterizing polymers and related materials. In Hyphenated Techniques in Polymer Chemistry: Thermal, Spectroscopic and Other Methods (Provder, T.; Urban, M.W.; Barth, H.G., editors). Washington, DC: ACS, 1994, pp. 55-72.
7. Scrivens, J.H., The characterization of synthetic polymer systems, Adv. Mass Spectrom., 1995, 13, 447-464.
8. Jackson, C.A.; Simonsick, W.J., Jr., Application of mass spectrometry to the characterization of polymers, Curr. Opin. Solid State Mater. Sci., 1997, 2, 661-667.
9. Saf, R.; Mirtl, C.; Hummel, K., Electrospray ionization mass spectrometry as an analytical tool for non-biological monomers, oligomers and polymers, Acta Polym., 1997, 48, 513-526.
10. Wu, K.J.; Odom, R.W., Characterizing synthetic polymers by MALDI MS, Anal. Chem., 1998, 70, 456A-461A.
11. Räder, H.J.; Schrepp, W., MALDI-TOF mass spectrometry in the analysis of synthetic polymers. Acta Polym., 1998, 49, 272-293.
12. Nielen, M.W.F., MALDI time-of-flight mass spectrometry of synthetic polymers, Mass Spec. Rev., 1999, 18, 309-344.
13. Pasch, H.; Ghahary, R., Analysis of complex polymers by MALDI-TOF mass spectrometry, Macromol. Symp., 2000, 152, 267-278.
14. Scrivens, J.H.; Jackson, A.T., Characterisation of synthetic polymer systems, Int. J. Mass Spectrom., 2000, 200, 261-276.
15. Haddleton, D.M., Mass spectrometry of polymers. In Emerging Themes in Polymer Science (Ryan, A.J., editor). Cambridge, UK: Royal Society of Chemistry, 2001.
16. Hanton, S.D., Mass spectrometry of polymers and polymer surfaces, Chem. Rev., 2001, 101, 527-569.
17. Montaudo, G.; Lattimer, R.P. (editors), Mass Spectrometry of Polymers. Boca Raton, FL: CRC Press, 2002.
18. McEwen, C.N.; Peacock, P.M., Mass spectrometry of chemical polymers, Anal. Chem., 2002, 74, 2743-2748.
19. Murgasova, R.; Hercules, D.M., Polymer characterization by combining liquid chromatography with MALDI and ESI mass spectrometry, Anal. Bioanal. Chem., 2002, 373, 481-489.
20. Macha, S.F.; Limbach, P.A., Matrix-assisted laser desorption/ionization (MALDI) mass spectrometry of polymers, Curr. Opin. Solid State Mater. Sci., 2002, 6, 213-220.
21. Pasch, H.; Schrepp, W., MALDI-TOF Mass Spectrometry of Synthetic Polymers. Berlin: Springer, 2003.
22. Murgasova, R.; Hercules, D.M., MALDI of synthetic polymers-an update. Int. J. Mass Spectrom., 2003, 226, 151-162.
23. McEwen, C.N., Recent developments in polymer characterization using mass spectrometry, Adv. Mass Spectrom., 2004, 16, 215-227.
24. Peacock, P.M.; McEwen, C.N., Mass spectrometry of synthetic polymers. Anal. Chem. 2004, 76, 3417-3428.
25. Montaudo, G.; Carroccio, S.; Montaudo, M.S.; Puglisi, C.; Samperi, F., Recent advances in MALDI mass spectrometry of polymers, Macromol. Symp., 2004, 218, 101-112.
26. Zhang, L.K.; Rempel, D.; Pramanik, B.N.; Gross, M.L., Accurate mass measurements by Fourier transform mass spectrometry, Mass Spectrom. Rev, 2005, 24, 286-309.
27. Montaudo, G.; Samperi, F.; Montaudo, M.S.; Carroccio, S.; Puglisi, C., Current trends in matrix-assisted laser desorption/ionization of polymeric materials, Eur. J. Mass Spectrom., 2005, 11, 1-14.
28. Jagtap, R.N.; Ambre, A.H., Overview literature on matrix-assisted laser desorption ionization mass spectrometry (MALDI MS): basics and its applications in characterizing polymeric materials, Bull. Mater. Sci., 2005, 28, 515-528.
29. Montaudo, G.; Samperi, F.; Montaudo, M.S., Characterization of synthetic polymers by MALDI-MS, Prog. Polym. Sci., 2006, 31, 277-357.
30. Peacock, P.M.; McEwen, C.N., Mass spectrometry of synthetic polymers, Anal. Chem., 2006, 78, 3957-3964.
31. Wesdemiotis, C.; Arnould, M.A.; Lee, Y.; Quirk, R.P., MALDI TOF mass spectrometry of the products from novel anionic polymerizations, Polym. Prepr., 2000, 41 (1), 629-630.
32. Arnould, M.A.; Polce, M.J.; Quirk, R.P.; Wesdemiotis, C., Probing chain-end functionalization reactions in living anionic polymerization via matrix-assisted laser desorption ionization time-of-flight mass spectrometry, Int. J. Mass Spectrom., 2004, 238, 245-255.
33. Polce, M.J.; Wesdemiotis, C., Introduction to mass spectrometry of polymers. In Polymer Mass Spectrometry (Lattimer, R.P.; Montaudo, G., editors). Boca Raton, FL, 2002, pp. 1-29.
34. Jackson, A.T.; Slade, S.E.; Scrivens, J.H., Characterisation of poly(alkyl methacrylate)s by means of electrospray ionisation-tandem mass spectrometry (ESI-MS/MS), Int. J. Mass Spectrom., 2004, 283, 265-277.
35. Arnould, M.A.; Wesdemiotis, C.; Geiger, R.J.; Park, M.A.; Buehner, R.W.; Vandervorst, D., Structural characterization of polyester copolymers by MALDI mass spectrometry, Prog. Org. Coat., 2002, 45, 305-312.
36. Wesdemiotis, C.; Pingitore, F.; Polce, M.J.; Russell, V.M.; Kim, Y.; Kausch, C.M.; Connors, T.H.; Medsker, R.E.; Thomas, R.R., Characterization of a poly(fluorooxetane) and poly(fluorooxetane-co-THF) by MALDI mass spectrometry, size exclusion chromatography, and NMR spectroscopy, Macromolecules, 2006, 39, 8369-8378.
37. Adamus, G.; Montaudo, M.S.; Montaudo, G.; Kowalczuk, M., Molecular architecture of poly[(R,S)-3-hydroxybutyrate-co-6-hydroxyhexanoate] and poly[(R,S)-3-hydroxybutyrate-co-(R,S)-2-hydroxyhexanoate] oligomers investigated by electrospray ionization ion-trap multistage mass spectrometry, Rapid Commun. Mass Spectrom., 2004, 18, 1436-1446.
38. Wollyung, K.M.; Wesdemiotis, C.; Nagy, A.; Kennedy, J.P., Synthesis and mass spectrometry characterization of centrally and terminally amine-functionalized polyisobutylenes, J. Polym. Sci. Part A: Polym. Chem., 2005, 43, 946-958.
39. De Hoffmann, E.; Stroobant, V., Mass Spectrometry. Principles and Applications. 2nd edition. Chichester: John Wiley & Sons, 2001.
40. Tanaka, K.; Waki, H.; Ido, S.; Akita, Y.; Yoshida, Y.; Yoshida, T., Protein and polymer analyses up to m/z 100,000 by laser ionization time-of-flight mass spectrometry, Rapid Commun. Mass Spectrom., 1988, 2, 151-153.
41. Karas, M.; Hillenkamp, F., Laser desorption ionization of proteins with molecular masses exceeding 10,000 daltons, Anal. Chem., 1988, 60, 2299-2301.
42. Fenn, J.B.; Mann, M.; Meng, C.K.; Wong, S.F.; Whitehouse, C.M., Electrospray ionization for mass spectrometry of large biomolecules, Science, 1989, 246, 64-71.
43. Craig, A.G.; Derrick, P.J., Spontaneous fragmentation of cationic polystyrene chains, J. Am. Chem. Soc., 1985, 107, 6707-6708.
44. Craig, A.G.; Derrick, P.J., Production and characterization of beams of polystyrene ions, Aust. J. Chem., 1986, 39, 1421-1434.
45. Jackson, A.T.; Jennings, R.C.K.; Scrivens, J.H.; Green, M.R.; Bateman, R.H., The characterization of complex mixtures by field desorption-tandem mass spectrometry, Rapid Commun. Mass Spectrom., 1998, 12, 1914-1924.
46. Lattimer, R.P.; Münster, H.; Budzikiewicz, H., Tandem mass spectrometry of poly glycols, Int. J. Mass Spectrom. Ion Proc., 1989, 90, 119-129.
47. Lattimer, R.P., Tandem mass spectrometry of poly(ethylene glycol) lithium-attachment ions, J. Am. Soc. Mass Spectrom., 1994, 5, 1072-1080.
48. + ions (X = H, Li, Na, K) from linear and cyclic polyglycols, J. Am. Soc. Mass Spectrom., 1994, 5, 1081-1092.
49. Jackson, A.T.; Yates, H.T.; Scrivens, J.H.; Critchley, G.; Brown, J.; Green, M.R.; Bateman, R.H., The application of matrix-assisted laser desorption/ionization combined with collision-induced dissociation to the analysis of synthetic polymers, Rapid Commun. Mass Spectrom., 1996, 10, 1668-1674.
50. Jackson, A.T.; Yates, H.T.; Scrivens, J.H.; Green, M.R.; Bateman, R.H., Utilizing matrix-assisted laser desorption/ionization-collision induced dissociation for the generation of structural information from poly(alkyl methacrylate)s, J. Am. Soc. Mass Spectrom., 1997, 8, 1206-1213.
51. Jackson, A.T.; Yates, H.T.; Scrivens, J.H.; Green, M.R.; Bateman, R.H., Matrix-assisted laser desorption/ionization-collision induced dissociation of poly(styrene), J. Am. Soc. Mass Spectrom., 1998, 9, 269-274.
52. Bottrill, A.R.; Giannakopulos, A.; Waterson, C.; Haddleton, D.M.; Lee, K.S.; Derrick, P.J., Determination of end groups of synthetic polymers by matrix-assisted laser desorption/ionization: high-energy collision-induced dissociation, Anal. Chem., 1999, 71, 3637-3641.
53. Lattimer, R.P., Mass spectral analysis of low-temperature pyrolysis products from poly(ethylene glycol), J. Anal. Appl. Pyr., 2000, 56, 61-78.
54. Lattimer, R.P.; Williams, R.C., Low-temperature pyrolysis products from a polyether-based urethane, J. Anal. Appl. Pyr., 2002, 63, 85-104.
55. Lattimer, R.P., Pyrolysis mass spectrometry of acrylic acid polymers, J. Anal. Appl. Pyr., 2003, 68-69, 3-14.
56. Busch, K.L.; Glish, G.L.; McLuckey, S.A., Mass Spectrometry/Mass Spectrometry. Techniques and Applications of Tandem Mass Spectrometry. New York: VCH Publishers, 1988.
57. Sleno, L.; Volmer, D.A., Ion activation methods for tandem mass spectrometry, J. Mass Spectrom., 2004, 39, 1091-1112.
58. McLafferty, F.W.; Tureček, F., Interpretation of Mass Spectra. 4th edition. Mill Valley, CA: University Science Books, 1993.
59. Cooks, R.G.; Ast, T.; Mabud, M.A., Collisions of polyatomic ions with surfaces, Int. J. Mass Spectrom. Ion Proc., 1990, 100, 209-265.
60. Dongré, A.R.; Somógyi, Á.; Wysocki, V.H., Surface-induced dissociation: an effective tool to probe structure, energetics, and fragmentation mechanisms of protonated peptides, J. Mass Spectrom., 1996, 31, 339-350.
61. Laskin, J.; Denisov, E.V.; Shukla, A.K.; Barlow, S.E.; Futrell, J.H., Surface-induced dissociation in a Fourier transform ion cyclotron resonance mass spectrometer: instrument design and evaluation, Anal. Chem., 2002, 74, 3255-3261.
62. Laskin, J.; Futrell, J.H., Activation of large ions in FT-ICR mass spectrometry, Mass Spectrom. Rev., 2005, 24, 135-167.
63. Xie, Y.; Lebrilla, C.B., Infrared multiphoton dissociation of alkali metal-coordinated oligosaccharides, Anal. Chem., 2003, 75, 1590-1598.
64. Wilson, J.J.; Brodbelt, J.S., Infrared multiphoton dissociation for enhanced de novo sequence interpretation of N-terminal sulfonated peptides in a quadrupole ion trap, Anal. Chem., 2006, 78, 6855-6862.
65. Zubarev, R.A.; Kelleher, N.L.; McLafferty, F.W., Electron capture dissociation of multiply charged protein cations: a nonergodic process, J. Am. Chem. Soc., 1998, 120, 3265-3266.
66. Zubarev, R.A., Reactions of polypeptide ions with electrons in the gas phase, Mass Spectrom. Rev., 2003, 22, 57-77.
67. Cooper, H.J.; Håkansson, K.; Marshall, A.G., The role of electron capture dissociation in biomolecular analysis, Mass Spectrom. Rev., 2005, 24, 201-222.
68. Syka, J.E.P.; Coon, J.J.; Schroeder, M.J.; Shabanowitz, J.; Hunt, D.F., Peptide and protein sequence analysis by electron transfer dissociation mass spectrometry, Proc. Natl. Acad. Sci., 2004, 101, 9528-9533.
69. Pitteri, S.J.; Chrisman, P.A.; McLuckey, S.A., Electron transfer ion/ion reactions of doubly protonated peptides: effect of elevated bath gas temperature, Anal. Chem., 2005, 77, 5662-5669.
70. Pitteri, S.; McLuckey, S.A., Recent developments in the ion/ion chemistry of high-mass multiply charged ions, Mass Spectrom. Rev., 2005, 24, 931-958.
71. Coon, J.J.; Shabanowitz, J.; Hunt, D.F.; Syka, J.E.P., Electron transfer dissociation of peptide anions, J. Am. Soc. Mass Spectrom., 2005, 16, 880-882.
72. Cerda, B.A.; Horn, D.M.; Breuker, K.; Carpenter, B.K.; McLafferty, F.W., Electron capture dissociation of multiply-charged oxygenated cations: a nonergodic process, Eur. Mass Spectrom., 1999, 5, 335-338.
73. Cerda, B.A.; Breuker, K.; Horn, D.M.; McLafferty, F.W., Charge/radical site initiation versus Coulombic repulsion for cleavage of multiply charged ions: charge solvation in poly(alkene glycol) ions, J. Am. Soc. Mass Spectrom., 2001, 12, 565-570.
74. Cerda, B.A.; Horn, D.M.; Breuker, K.; McLafferty, F.W., Sequencing of specific copolymer oligomers by electron-capture dissociation mass spectrometry, J. Am. Chem. Soc., 2002, 124, 9287-9291.
75. Koster, S.; Duursma, M.C.; Boon, J.J.; Heeren, R.M.A.; Ingemann, S.; van Benthem, R.A.T. M.; de Koster, C.G., Electron capture and collisionally activated dissociation mass spectrometry of doubly charged hyperbranched polyesteramides, J. Am. Soc. Mass Spectrom., 2003, 14, 332-341.
76. Lee, S.; Han, S.Y.; Lee, T.G.; Chung, G.; Lee, D.; Oh, H.B., Observation of pronounced b*, y cleavages in the electron capture dissociation mass spectrometry of polyamidoamine (PAMAM) dendrimer ions with amide functionalities, J. Am. Soc. Mass Spectrom., 2006, 17, 536-543.
77. Tang, X.; Ens, W.; Mayer, F.; Standing, K.G.; Westmore, J.B., Measurement of unimolecular decay in peptides of masses greater than 1200 units by a reflecting time-of-flight mass spectrometer, Rapid Commun. Mass Spectrom., 1989, 3, 443-448.
78. Spengler, B.; Kirsch, D.; Kaufmann, R., Metastable decay of peptides and proteins in matrix-assisted laser-desorption mass spectrometry, Rapid Commun. Mass Spectrom., 1991, 5, 198-202.
79. Spengler, B., Post-source decay analysis in matrix-assisted laser desorption/ionization mass spectrometry of biomolecules, J. Mass Spectrom., 1997, 32, 1019-1036.
80. Cotter, R.J., Time-of-Flight Mass Spectrometry: Instrumentation and Applications in Biological Research. Washington, DC: ACS Professional Reference Books, American Chemical Society, 1997.
81. Hoteling, A.J.; Owens, K.G., Improved PSD and CID on a MALDI TOFMS, J. Am. Soc. Mass Spectrom., 2004, 15, 523-535.
82. Hoteling, A.J.; Kawaoka, K.; Goodberlet, M.C.; Yu, W.-M.; Owens, K.G., Optimization of matrix-assisted laser desorption/ionization time-of-flight collision-induced dissociation using poly(ethylene glycol), Rapid Commun. Mass Spectrom., 2003, 17, 1671-1676.
83. Scrivens, J.H.; Jackson, A.T.; Yates, H.T.; Green, M.R.; Critchley, G.; Brown, J.; Bateman, R.H.; Bowers, M.T.; Gidden, J., The effect of the variation of cation in the matrix-assisted laser desorption/ ionization-collision induced dissociation (MALDI-CID) spectra of oligomeric systems, Int. J. Mass Spectrom. Ion Proc., 1997, 165/166, 363-375.
84. Przybilla, L.; Räder, H.-J.; Müllen, K., Post-source decay fragment ion analysis of polycarbonates by matrix-assisted laser desorption/ionization time-of-flight mass spectrometry, Eur. Mass Spectrom., 1999, 5, 133-143.
85. Muscat, D.; Henderickx, H.; Kwakkenbos, G.; van Benthem, R.; de Koster, C.G.; Fokkens, R.; Nibbering, N.M.M., In-source decay of hyperbranched polyesteramides in matrix-assisted laser desorption-ionization time-of flight mass spectrometry, J. Am. Soc. Mass Spectrom., 2000, 11, 218-227.
86. Goldschmidt, R.J.; Wetzel, S.J.; Blair W.R.; Guttman, C.M., Post-source decay in the analysis of polystyrene by matrix-assisted laser desorption/ionization time-of-flight mass spectrometry, J. Am. Soc. Mass Spectrom., 2000, 11, 1095-1106.
87. Przybilla, L.; Francke, V.; Räder, H.J.; Müllen, K., Block length determination of a poly(ethylene oxide)-b-poly(p-phenylene ethynylene) diblock copolymer by means of MALDI-TOF mass spectrometry combined with fragment-ion analysis, Macromolecules, 2001, 34, 4401-4405.
88. Kéki, S.; Bodnár, I.; Borda, J.; Deák, G.; Batta, G.; Zsuga, M., Matrix-assisted laser desorption/ ionization mass spectrometric study of the oligomers formed from lactic acid and diphenylmethane diisocyanate, Macromolecules, 2001, 34, 7288-7293.
89. Murgasova, R.; Hercules, D.M., Matrix-assisted laser desorption/ionization collision-induced dissociation of linear single oligomers of nylon-6, J. Mass Spectrom., 2001, 36, 1098-1107.
90. Adhiya, A.; Wesdemiotis, C., Poly(propylene imine) dendrimer conformations in the gas phase: a tandem mass spectrometry study, Int. J. Mass Spectrom., 2002, 214, 75-88.
91. Laine, O.; Laitinen, T.; Vainiotalo, P., Characterization of polyesters prepared from three different phthalic acid isomers by CID-ESI-FT-ICR and PSD-MALDI-TOF mass spectrometry, Anal. Chem., 2002, 74, 4250-4258.
92. Fournier, I.; Marie, A.; Lesage, D.; Bolbach, G.; Fournier, F.; Tabet, J.C., Post-source decay time-of-flight study of fragmentation mechanisms of protonated synthetic polymers under matrix-assisted laser desorption/ionization conditions, Rapid Commun. Mass Spectrom., 2002, 16, 696-704.
93. Laine, O.; Trimpin, S.; Räder, H.J.; Müllen, K., Changes in post-source decay fragmentation behavior of poly(methyl methacrylate) polymers with increasing molecular weight studied by matrix-assisted laser desorption/ionization time-of-flight mass spectrometry, Eur. J. Mass Spectrom., 2003, 9, 195-201.
94. Neubert, H.; Knights, K.A.; de Miguel, Y.R.; Cowan, D.A., MALDI TOF post-source decay investigation of alkali metal adducts of apolar polypentylresorcinol dendrimers, Macromolecules, 2003, 36, 8297-8303.
95. Ameduri, B.; Ladavière, C.; Delolme, F.; Boutevin, B., First MALDI-TOF mass spectrometry of vinylidene fluoride telomers endowed with low defect chaining, Macromolecules, 2004, 37, 7602-7609.
96. Hanton, S.D.; Parees, D.M.; Owens, K.G., MALDI PSD of low molecular weight ethoxylated polymers, Int. J. Mass Spectrom., 2004, 238, 257-264.
97. Berndt, U.E.Ch.; Zhou, T.; Hider, R.C.; Liu, Z.D.; Neubert, H., Structural characterization of chelator-terminated dendrimers and their synthetic intermediates by mass spectrometry, J. Mass Spectrom., 2005, 40, 1203-1214.
98. Osaka, I.; Watanabe, M.; Takama, M.; Murakami, M.; Arakawa, R., Characterization of linear and cyclic polylactic acids and their solvolysis products by electrospray ionization mass spectrometry, J. Mass Spectrom., 2006, 41, 1369-1377.
99. Vergne, M.J.; Li, H.; Murgasova, R.; Hercules, D.M., Synthesis and mass spectral characterization of poly(amic methylester) oligomers, Macromolecules, 2006, 39, 6928-6935.
100. Jackson, A.T.; Jennings, K.R.; Scrivens, J.H., Generation of average mass values and end group information of polymers by means of a combination of matrix-assisted laser desorption/ionization-mass spectrometry and liquid secondary ion-tandem mass spectrometry, J. Am. Soc. Mass Spectrom., 1997, 8, 76-85.
101. Gidden, J.; Jackson, A.T.; Scrivens, J.H.; Bowers, M.T., Gas phase conformations of synthetic polymers: poly(methyl methacrylate) oligomers cationized by sodium ions, Int. J. Mass Spectrom., 1999, 188, 121-130.
102. Stolarzewicz, A.; Neugebauer, D.; Silberring, J., Electrospray ionization tandem mass spectrometry for poly(propylene oxide) starting and end group analysis, Rapid Commun. Mass Spectrom., 1999, 13, 2469-2473.
103. Borman, C.D.; Jackson, A.T.; Bunn, A.; Cutter, A.L.; Irvine, D.J., Evidence for the low thermal stability of poly(methyl methacrylate) polymer produced by atom transfer radical polymerisation, Polymer, 2000, 41, 6015-6020.
104. Jackson, A.T.; Bunn, A.; Hutchings, L.R.; Kiff, F.T.; Richards, R.W.; Williams, J.; Green, M.R.; Bateman, R.H., The generation of end group information from poly(styrene)s by means of matrix-assisted laser desorption/ionisation-collision induced dissociation, Polymer, 2000, 41, 7437-7450.
105. +-coordinated polyglycol radicals, a new class of distonic radical ions, J. Am. Chem. Soc., 2000, 122, 12786-12794.
106. Yalcin, T.; Gabryelski, W.; Li, L., Structural analysis of polymer end groups by electrospray ionization high-energy collision-induced dissociation tandem mass spectrometry, Anal. Chem., 2000, 72, 3847-3852.
107. Botrill, A.R.; Giannakopulos, A.; Millichope, A.; Lee, K.S.; Derrick, P.J., Combination of time-of-flight mass analysers with magnetic-sector instruments: in-line and perpendicular arrangements. Applications to poly(ethylene glycol) with long-chain end groups, Eur. J. Mass Spectrom., 2000, 6, 225-232.
108. Jackson, A.T.; Bunn, A.; Priestnall, I.M.; Borman, C.D.; Irvine, D.J., Molecular spectroscopic characterisation of poly(methyl methacrylate) generated by means of atom transfer radical polymerisation (ATRP), Polymer, 2006, 47, 1044-1054.
109. Jackson, A.T.; Green, M.R.; Bateman, R.H., Generation and end-group information from polyethers by matrix-assisted laser desorption/ionisation collision-induced dissociation mass spectrometry, Rapid Commun. Mass Spectrom., 2006, 20, 3542-3550.
110. Bateman, R.H.; Green, M.R.; Scott, G., A combined magnetic sector-time-of-flight mass spectrometer for structural determination studies by tandem mass spectrometry, Rapid Commun. Mass Spectrom., 1995, 9, 1227-1233.
111. Morris, H.R.; Paxton, T.; Dell, A.; Langhorne, J.; Berg, M.; Bordoli, R.S.; Hoyes, J.; Bateman, R.H., High sensitivity collisionally activated decomposition tandem mass spectrometry on a novel quadrupole/orthogonal-acceleration time-of-flight mass spectrometer, Rapid Commun. Mass Spectrom., 1996, 10, 889-896.
112. Q-ToF Ultima MALDI User's Guide. Atlas Park, Manchester: Micromass UK Limited M22 5PP. Available at http://www.waters.com.
113. Harvey, D.J.; Bateman, R.H.; Bordoli, R.S.; Tyldesley, R., Ionisation and fragmentation of complex glycans with a quadrupole time-of-flight mass spectrometer fitted with a matrix-assisted laser desorption/ionisation ion source, Rapid Commun. Mass Spectrom., 2000, 14, 2135-2142.
114. Jackson, A.T.; Williams, J.P.; Scrivens, J.H., Desorption electrospray ionization mass spectrometry of low molecular weight synthetic polymers, Rapid Commun. Mass Spectrom., 2006, 20, 2717-2727.
115. Collins, S.; Rimmer, S., Tandem (quadrupole-time-of-flight) electrospray mass spectrometry of oligo(vinyl acetates) with isopropylol or (1-hydroxyethyl)-2-oxyisopropanyl end groups, Rapid Commun. Mass Spectrom., 2004, 18, 3075-3078.
116. Jackson, A.T.; Scrivens, J.H.; Williams, J.P.; Baker, E.S.; Gidden, J.; Bowers, M.T., Microstructural and conformational studies of polyether copolymers, Int. J. Mass Spectrom., 2004, 238, 287-297.
117. Terrier, P.; Buchmann, W.; Desmazières, B.; Tortajada, J., Block lengths and block sequence of linear triblock and glycerol derivative diblock copolyethers by electrospray ionization-collision-induced dissociation mass spectrometry, Anal. Chem., 2006, 78, 1801-1806.
118. Jiang, X.; Schoenmakers, P.J.; van Dongen, J.L.J.; Lou, X.; Lima, V.; Brokken-Zijp, J., Mass spectrometric characterization of functional poly(methyl methacrylate) in combination with critical liquid chromatography, Anal. Chem., 2003, 75, 5517-5524.
119. Warburton, K.E.; Clench, M.R.; Ford, M.J.; White, J.; Rimmer, D.A.; Carolan, V.A., Characterisation of derivatised monomeric and prepolymeric isocyanates by matrix-assisted laser desorption/ ionization time-of-flight mass spectrometry and structural elucidation by tandem mass spectrometry, Eur. J. Mass Spectrom., 2005, 11, 565-574.
120. Medzihradszky, K.F.; Campbell, J.M.; Baldwin, M.A.; Falick, A.M.; Juhasz, P.; Vestal, M.L.; Burlingame, A.L., The characteristics of peptide collision-induced dissociation using a high-performance MALDI-TOF/TOF tandem mass spectrometer, Anal. Chem., 2000, 72, 552-558.
121. Yergey, A.L.; Coorssen, J.R.; Backlund, P.S., Jr.; Blank, P.S.; Humphrey, G.A.; Zimmerberg, J.; Campbell, J.M.; Vestal, M.L., De novo sequencing of peptides using MALDI-TOF/TOF, J. Am. Soc. Mass Spectrom., 2002, 13, 784-791.
122. Suckau, D.; Resemann, A.; Schuerenberg, M.; Hufnagel, P.; Franzen, J.; Holle, A., A novel MALDI LIFT-TOF/TOF mass spectrometer for proteomics, Anal. Bioanal. Chem., 2003, 376, 952-965.
123. Giannakopulos, A.E.; Thomas, B.; Colburn, A.W.; Reynolds, D.J.; Raptakis, E.N.; Makarov, A.A.; Derrick, P.J., Tandem time-of-flight mass spectrometer (TOF-TOF) with a quadratic-field ion mirror, Rev. Sci. Instrum., 2002, 73, 2115-2123.
124. Rizzarelli, P.; Puglisi, C.; Montaudo, G., Sequence determination in aliphatic poly(ester amide)s by matrix-assisted laser desorption/ionization time-of-flight and time-of-flight/time-of-flight tandem mass spectrometry, Rapid Commun. Mass Spectrom., 2005, 19, 2407-2418.
125. Rizzarelli, P.; Puglisi, C.; Montaudo, G., Matrix-assisted laser desorption/ionization time-of-flight/ time-of-flight tandem mass spectra of poly(butylene adipate), Rapid Commun. Mass Spectrom., 2006, 20, 1683-1694.
126. Vergne, M.J., Mass Spectrometry of Functionalized Polymers. PhD Dissertation, Nashville, TN: Vanderbilt University, 2004.
127. Arnould, M.A. (Xerox Corporation), unpublished results.
128. Kamel, A.; Prakash, C., High performance liquid chromatography/atmospheric pressure ionization/ tandem mass spectrometry (HPLC/API/MS/MS) in drug metabolism and toxicology, Current Drug Metabolism, 2006, 7, 837-852.
129. Smyth, W.F., Electrospray ionization-mass spectrometry (ESI-MS) and liquid chromatography-electrospray ionization-mass spectrometry (LC-ESI-MS) of selected pharmaceuticals, Current Pharmaceutical Analysis, 2006, 2, 299-311.
130. Dolan, A.R.; Wood, T.D., Synthesis and characterization of low molecular weight oligomers of soluble polyalanine by electrospray ionization mass spectrometry, Synth. Met., 2004, 143, 243-250.
131. Giguère, M.-S.; Mayer, P.M., Climbing the internal energy ladder: the unimolecular decomposition of ionized poly(vinyl acetate), Int. J. Mass Spectrom., 2004, 231, 59-68.
132. Cooks, R.G.; Kaiser, R.E., Jr., Quadrupole ion trap mass spectrometry, Acc. Chem. Res., 1990, 23, 213-219.
133. Todd, J.F.J.; Penman, A.D., The recent evolution of the quadrupole ion trap mass spectrometer-an overview, Int. J. Mass Spectrom. Ion Proc., 1991, 106, 1-20.
134. March, R.E., A musing on the present state of the ion trap and prospects for future applications, Org. Mass Spectrom., 1991, 26, 627-632.
135. McLuckey, A.A.; Van Berkel, G.J.; Goeringer, D.E.; Glish, G.L., Ion trap mass spectrometry of externally generated ions, Anal. Chem., 1994, 66, 689A-696A.
136. Qin, J.; Chait, B.T., Identification and characterization of posttranslational modifications of proteins by MALDI ion trap mass spectrometry, Anal. Chem., 1997, 69, 4002-4009.
137. Jonscher, K.R.; Yates, J.R., III., The quadrupole ion trap mass spectrometer-a small solution to a big problem, Anal. Biochem., 1997, 244, 1-15.
138. March, R.E., An introduction to quadrupole ion trap mass spectrometry, J. Mass Spectrom., 1997, 32, 351-369.
139. McLuckey, S.A.; Wells, J.M., Mass analysis at the advent of the 21st century, Chem. Rev., 2001, 101, 571-606.
140. March, R.E., Quadrupole ion trap mass spectrometry: a view at the turn of the century, Int. J. Mass Spectrom., 2000, 200, 285-312.
141. March, R.E.; Todd, J.F.J., Quadrupole Ion Trap Mass Spectrometry. 2nd edition. Hoboken, NJ: Wiley-Interscience, 2005.
142. Esquire-LC Operations Manual, Vol. 1, version 3.1. Bremen, Germany: Bruker Daltonik GmbH, 1999.
143. Jedliski, Z.; Adamus, G.; Kowalczuk, M.; Schubert, R.; Szewczuk, Z.; Stefanowicz, P., Electrospray tandem mass spectrometry of poly(3-hydroxybutanioc acid) end groups analysis and fragmentation mechanism, R apid Commun. Mass Spectrom., 1998, 12, 357-360.
144. Arslan, H.; Adamus, G.; Hazer, B.; Kowalczuk, M., Electrospray ionisation tandem mass spectrometry of poly [(R,S)-3-hydroxybutanoic acid] telechelics containing primary hydroxy end groups, Rapid Commun. Mass Spectrom., 1999, 13, 2433-2438.
145. McLuckey, S.A.; Asano, K.G.; Gregory Schaaff, T.; Stephenson, J.L., Jr., Ion trap collisional activation of protonated poly(propylene imine) dendrimers: generations 1-5. Int. J. Mass Spectrom., 2000, 195/196, 419-437.
146. Adamus, G.; Kowalczuk, M., Electrospray multistep ion trap mass spectrometry for the structural characterization of poly[(R,S)-3-hydroxybutanoic acid] containing a ß-lactam end group, Rapid Commun. Mass Spectrom., 2000, 14, 195-202.
147. Chen, R.; Tseng, A.M.; Uhing, M.; Li, L., Application of an integrated matrix-assisted laser desorption/ionization time-of-flight, electrospray ionization mass spectrometry and tandem mass spectrometry approach to characterizing complex polyol mixtures. J. Am. Soc. Mass Spectrom., 2001, 12, 55-60.
148. Chen, R.; Li, L., Lithium and transition metal ions enable low energy collision-induced dissociation of polyglycols in electrospray ionization mass spectrometry, J. Am. Soc. Mass Spectrom., 2001, 12, 832-839.
149. Bogan, M.J.; Agnes, G.R., Poly(ethylene glycol) doubly and singly cationized by different alkali metal ions: relative cation ion affinities and cation-dependent resolution in a quadrupole ion trap mass spectrometer, J. Am. Soc. Mass Spectrom., 2002, 13, 177-186.
150. Marie, A.; Fournier, F.; Tabet, J.C.; Améduri, B.; Walker, J., Collision-induced dissociation studies of poly(vinylidene) fluoride telomers in an electrospray-ion trap mass spectrometer, Anal. Chem., 2002, 74, 3213-3220.
151. Yuan, G.; Tang, F.; Zhu, C.J.; Liu, Y.; Zhao, Y.F., Fragmentation mechanisms of polyamides containing N-methylimidazole by electrospray ionization tandem mass spectrometry, Rapid Commun. Mass Spectrom., 2003, 17, 2015-2018.
152. Creaser, C.S.; Reynolds, J.C.; Hoteling, A.J.; Nichols, W.F.; Owens, K.G., Atmospheric pressure matrix-assisted laser desorption/ionisation ion trap mass spectrometry of synthetic polymers: a comparison with vacuum matrix-assisted laser desorption/ionization time-of-flight mass spectrometry, Eur. J. Mass Spectrom., 2003, 9, 33-44.
153. Okuno, S.; Ohmoto, M.; Arakawa, R., Analysis of polypropyleneglycols using electrospray ionization mass spectrometry: effects of cationizing agents on the mass spectra, Eur. J. Mass Spectrom., 2003, 9, 97-103.
154. Yuan, G.; Zhou, J., Electrospray ionization mass spectral fragmentation mechanisms of DNA-recognizing polyamides containing N-methylpyrrole and N-methylimidazole, Rapid Commun. Mass Spectrom., 2004, 18, 1397-1402.
155. Wang, J.; Zhou, J.; Yuan, G., Electrospray negative ion mass spectrometry of polyamides containing N-methylpyrrole and N-methylimidazole, J. Mass Spectrom., 2005, 40, 688-689.
156. Arnould, M.A.; Vargas, R.; Buehner, R.W.; Wesdemiotis, C., Tandem mass spectrometry characteristics of polyester anions and cations formed by electrospray ionization, Eur. J. Mass Spectrom., 2005, 11, 243-256.
157. Zhou, G.-J.; Xu, P.-X.; Ye, Y.; Zhao, Y.-F., Electrospray ionization tandem mass spectrometry investigation of the polymerization of tetrahydrofuran initiated by phosphorus oxychloride, Eur. J. Mass Spectrom., 2005, 11, 319-324.
158. Hanton, S.D.; Parees, D.M.; Zweigenbaum, J., The fragmentation of ethoxylated surfactants by AP-MALDI-QIT, J. Am. Soc. Mass Spectrom., 2006, 17, 453-458.
159. Laiko, V.V.; Baldwin, M.A.; Burlingame, A.L., Atmospheric pressure matrix-assisted laser desorption/ionization mass spectrometry, Anal. Chem., 2000, 72, 652-657.
160. Laiko, V.V.; Moyer, S.C.; Cotter, R.J., Atmospheric pressure MALDI/ion trap mass spectrometry, Anal. Chem., 2000, 72, 5239-5243.
161. Chaicharoen, K.; Polce, M.J.; Wesdemiotis, C., MP11-231, tandem mass spectrometry of poly(methyl methacrylate)s. Proceedings of the 54th ASMS Conference on Mass Spectrometry and Allied Topics, Seattle, WA, May 28-June 1, 2006.
162. Schwartz, J.C.; Syka, J.E.P.; Quarmby, S.T., TODam 11:35, improving the fundamentals of MS n on 2D linear ion traps: new ion activation and isolation techniques. Proceedings of the 53rd ASMS Conference on Mass Spectrometry and Allied Topics, San Antonio, TX, June 5-9, 2005.
163. Cunningham, C., Jr.; Glish, G.L.; Burinsky, D.J., High amplitude short time excitation: a method to form and detect low mass product ions in a quadrupole ion trap mass spectrometer, J. Am. Soc. Mass Spectrom., 2006, 17, 81-84.
164. Schwartz, J.C.; Senko, M.W.; Syka, J.E.P., A two-dimensional quadrupole ion trap mass spectrometer, J. Am. Soc. Mass Spectrom., 2002, 13, 659-669.
165. Hager, J.W., A new linear ion trap mass spectrometer, Rapid Commun. Mass Spectrom., 2002, 16, 512-526.
166. Riter, L.S.; Gooding, K.M.; Hodge, B.D.; Julian, R.K., Jr., Comparison of the Paul ion trap to the linear ion trap for use in global proteomics, Proteomics, 2006, 6, 1735-1740.
167. Available at http://www.ssi.shimadzu.com/products/product.cfm?product=lcms_it_tof.
168. Available at http://www.shimadzu-biotech.net/pages/products/1/aximaqit.php.
169. Available at http://www.hitachi-hitec.com/global/science/ms/nanofrontier.html.
170. Hashimoto, Y.; Hasegawa, H.; Satake, H.; Baba, T.; Waki, I., Duty cycle enhancement of an orthogonal acceleration TOF mass spectrometer using an axially resonant excitation linear ion trap, J. Am. Soc. Mass Spectrom., 2006, 17, 1669-1674.
171. Okuno, S.; Kiuchi, M.; Arakawa, R., Structural characterization of polyethers using matrix-assisted laser desorption/ionization quadrupole ion trap time-of-flight mass spectrometry, Eur. J. Mass Spectrom., 2006, 12, 181-187.
172. Hu, Q.; Noll, R.J.; Li, H.; Makarov, A.; Hardman, M.; Cooks, R.G., The Orbitrap: a new mass spectrometer, J. Mass Spectrom., 2005, 40, 430-443.
173. Available at http://www.thermo.com/com/cda/product/detail/0,10121795,00.html?CA=orbitrap.
174. Makarov, A.; Denisov, E.; Kholomeev, A.; Balschun, W.; Lange, O.; Strupat, K.; Horning, S., Performance evaluation of a hybrid linear ion trap/Orbitrap mass spectrometer, Anal. Chem., 2006, 78, 2113-2120.
175. Pastor, S.J.; Wilkins, C.L., Sustained off-resonance irradiation and collision-induced dissociation for structural analysis of polymers by MALDI-FTMS, Int. J. Mass Spectrom. Ion Proc., 1998, 175, 81-92.
176. Mariarz, E.P., III; Baker, G.A.; Wood, T.D., Capitalizing on the high mass accuracy of electrospray ionization Fourier transform mass spectrometry for synthetic polymer characterization: a detailed investigation of poly(dimethylsiloxane), Macromolecules, 1999, 32, 4411-4418.
177. Koster, S.; Duursma, M.C.; Boon, J.J.; Nielen, M.W.F.; de Koster, C.G.; Heeren, R.M.A., Structural analysis of synthetic homo-and copolyesters by electrospray ionization on a Fourier transform ion cyclotron resonance mass spectrometer, J. Mass Spectrom., 2000, 35, 739-748.
178. Koster, S.; de Koster, C.G.; van Benthem, R.A.T.M.; Duursma, M.C.; Boon, J.J.; Heeren, R.M.A., Structural characterization of hyperbranched polyesteramides: MS n and the origin of species, Int. J. Mass Spectrom., 2001, 210/211, 591-602.
179. Koster, S.; Duursma, M.C.; Guo, X.; van Benthem, R.A.T.M.; de Koster, C.G.; Boon, J.J.; Heeren, R.M.A., Isomer separation of hyperbranched polyesteramides with gas-phase H/D exchange and a novel MS n approach: DoDIP, J. Mass Spectrom., 2002, 37, 792-802.
180. McDonnell, L.A.; Derrick, P.J.; Powell, B.B.; Double, P., Sustained off-resonance irradiation collision-induced dissociation of linear, substituted and cyclic polyesters using a 9.4 T Fourier transform ion cyclotron resonance mass spectrometer, Eur. J. Mass Spectrom., 2003, 9, 117-128.
181. Han, S.Y.; Lee, S.; Oh, H.B., Comparable electron capture efficiencies for various protonated sites on the 3rd generation poly(propylene imine) dendrimer ions: applications by SORI-CAD and electron capture dissociation mass spectrometry (ECD MS), Bull. Korean Chem. Soc., 2005, 26, 740-746.
182. Felder, T.; Schalley, C.A.; Fakhrnabavi, H.; Lukin, O., A combined ESI-and MALDI-MS(/MS) study of peripherally persulfonylated dendrimers: false negative results by MALDI-MS and analysis of defects, Chem. Eur. J., 2005, 11, 5625-5636.
183. Wallace, W.E., Report on the 4th annual NIST polymer mass spectrometry workshop: " Future directions in soft ionization of polymers, " J. Am. Soc. Mass Spectrom., 2006, 17, 280-282.
184. Roepstorff, P.; Fohlman, J., Proposal for common nomenclature for sequence ions in mass spectra of peptides, Biomed. Mass Spectrom., 1984, 11, 601.
185. Biemann, K., Contributions of mass spectrometry to peptide and protein structure, Biomed. Environ. Mass Spectrom., 1988, 16, 99-111.
186. Domon, B.; Costello, C.E., A systematic nomenclature for carbohydrate fragmentations in FAB-MS/ MS spectra of glycolconjugates, Glycoconjugate J., 1988, 5, 397-409.
187. McLuckey, S.A.; Van Berkel, G.J.; Glish, G.L., Tandem mass spectrometry of small, multiply charged oligonucleotides, J. Am. Soc. Mass Spectrom., 1992, 3, 60-70.
188. Claeys, M.; Nizigiyimana, L.; Van den Heuvel, H.; Derrick, P.J., Mechanistic aspects of charge-remote fragmentation in saturated and mono-unsaturated fatty acid derivatives: evidence for homolytic cleavage, Rapid Commun. Mass Spectrom., 1996, 10, 770-774.
189. Jackson, A.T.; Lattimer, R.P.; Price, P.C.; Wallace, W.E.; Polce, M.J.; Wesdemiotis, C., 2705, Proposal for a common nomenclature of fragment ions in the mass spectra of synthetic polymers. Proceedings of the 54th ASMS Conference on Mass Spectrometry and Allied Topics, Seattle, WA, May 28-June 1, 2006.
190. Cheng, C.; Gross, M.L., Applications and mechanisms of charge-remote fragmentation, Mass Spectrom. Rev., 2000, 19, 398-420.
191. Gross, M.L., Charge-remote fragmentation: an account of research on mechanism and applications, Int. J. Mass Spectrom., 2000, 200, 611-624.
192. Thomya, P., Structural Characterization of Complex Polymer Systems by Degradation/Mass Spectrometry. PhD Dissertation, The University of Akron: Akron, Ohio, 2006.
193. Available at http://webbook.nist.gov/chemistry/.
194. Dongre, A.R.; Jones, J.L.; Somogyi, A.; Wysocki, V., Influence of peptide composition, gas-phase basicity, and chemical modification on fragmentation efficiency: evidence for the mobile proton model, J. Am. Chem. Soc., 1996, 118, 8365-8374.
195. Carey, F.A.; Sundberg, R.J., Advanced Organic Chemistry. Part B: Reactions and Synthesis. 4th edition. New York: Kluwer Academic/Plenum Publishers, 2001.
196. Chaicharoen, K., Mass and Tandem Mass Spectrometric Studies on Synthetic Polymers. PhD Dissertation, The University of Akron: Akron, Ohio, 2008.
197. Chen, H., End group-assisted siloxane bond cleavage in the gas phase, J. Am. Soc. Mass Spectrom., 2003, 14, 1039-1048.
198. Leigh, A.M.; Wang, P.; Polce, M.J.; Wesdemiotis, C., MP-340, tandem mass spectrometry of poly(dimethylsiloxane)s. Proceedings of the 53rd ASMS Conference on Mass Spectrometry and Allied Topics, San Antonio, TX, June 5-9, 2005.
199. Polce, M.J.; Wesdemiotis, C., TOEam 10:55, Fundamental aspects of polymer fragmentation. Proceedings of the 51st ASMS Conference on Mass Spectrometry and Allied Topics, Montr é al, Quebec, Canada, June 8-12, 2003.
200. Polce, M.J.; Wesdemiotis, C., TPP 303, Tandem mass spectrometry of polyisoprene, polybutadiene, and poly(2-vinyl pyridine). Proceedings of the 52nd ASMS Conference on Mass Spectrometry and Allied Topics, Nashville, TN, May 23-27, 2004.
201. Polce, M.J.; Wesdemiotis, C., Proposed modifications to MALDI-CID fragmentation mechanisms of silver ionized polystyrene oligomers. Proceedings of the 54th ASMS Conference on Mass Spectrometry and Allied Topics, Seattle, WA, May 28-June 1, 2006.
202. Polce, M.J.; Ocampo, M.; Quirk, R.P.; Wesdemiotis, C., Tandem mass spectrometry characteristics of silver-cationized polystyrenes: backbone degradation via free radical chemistry, Anal. Chem., 2008, 80, 347-354.
203. Polce, M.J.; Ocampo, M.; Quirk, R.P.; Leigh, A.M.; Wesdemiotis, C., Tandem mass spectrometry characteristics of silver-cationized polystyrenes: internal energy, size, and chain end versus backbone substituent effects, Anal. Chem., 2008, 80, 355-362.
204. Gies, A.P.; Vergne, M.J.; Orndorff, R.L.; Hercules, D.M., MALDI-TOF/TOF CID study of polystyrene fragmentation reactions, Macromolecules, 2007, 40, 7493-7504.
205. Cameron, G.C.; MacCallum, J.R., Thermal degradation of polystyrene, J. Macromol. Sci., Rev. Macromol. Chem., 1967, 1, 327-359.
206. Schroeder, U.K.O.; Ebert, K.H.; Hamielec, A.W., On the kinetics and mechanism of thermal degradation of polystyrene: 2. formation of volatile compounds, Macromol. Chem., 1984, 185, 991-1001.
207. Scott, G. (editor). Mechanisms of Polymer Degradation and Stabilization. London: Elsevier, 1990.
208. Tsuge, S.; Ohtani, H., Pyrolysis gas chromatography/mass spectrometry (Py-GC/MS). In Mass Spectrometry of Polymers (Montaudo, G.; Lattimer, R.P., editors). Boca Raton, FL: CRC Press, 2002, pp. 113-147.
209. Bauld, N.L., Radicals, Radical Ions, and Triplets: The Spin Bearing Intermediates of Organic Chemistry. New York: Wiley, 1997.
210. Suebold, F.H., Jr., The rearrangement of the neophyl radical, J. Am. Chem. Soc., 1953, 75, 2532-2533.
211. Tokmakov, I.V.; Lin, M.C., Combined quantum chemical/RRKM-ME computational study of the phenyl + ethylene, vinyl + benzene, and H + styrene reactions, J. Phys. Chem. A, 2004, 108, 9697-9714.