Bladder cancer cells re-educate TAMs through lactate shuttling in the microfluidic cancer microenvironment

Oncotarget

Volumn 6, Issue 36, 2015, Pages 39196-39210

  Zhao, Yang ^a   Wang, Degui ^b   Xu, Ting ^c   Liu, Pengfei ^a   Cao, Yanwei ^a   Wang, Yonghua ^a   Yang, Xuecheng ^a   Xu, Xiaodong ^a   Wang, Xinsheng ^a   Niu, Haitao ^a  

^a QINGDAO UNIVERSITY   (China)

^b LANZHOU UNIVERSITY   (China)

^c 401 Hospital of PLA   (China)

Author keywords

Bladder cancer; Lactate; Microfluidic chips; Re education; Tumor associated macrophage

Indexed keywords

ARGINASE 1; HYPOXIA INDUCIBLE FACTOR 1ALPHA; INDUCIBLE NITRIC OXIDE SYNTHASE; LACTIC ACID; NITRIC OXIDE; TRANSCRIPTION FACTOR RELA;

ANIMAL CELL; ARTICLE; BLADDER CANCER CELL LINE; CELL MOTILITY; CELL VIABILITY; COCULTURE; CONTROLLED STUDY; HUMAN; HUMAN CELL; IMMUNOFLUORESCENCE; LACTATE SHUTTLING; MACROPHAGE MIGRATION; METASTASIS; MICROFLUIDIC ANALYSIS; MICROSCOPY; MOUSE; NONHUMAN; NUCLEAR REPROGRAMMING; PROTEIN EXPRESSION; TRANSITIONAL CELL CARCINOMA; TRANSPORT AT THE CELLULAR LEVEL; TUMOR ASSOCIATED LEUKOCYTE; TUMOR MICROENVIRONMENT; WESTERN BLOTTING; ANIMAL; BLADDER TUMOR; CELL POLARITY; LAB ON A CHIP; MACROPHAGE; METABOLISM; MICROFLUIDICS; PATHOLOGY; PHYSIOLOGY; RAW 264.7 CELL LINE;

ANIMALS; CARCINOMA, TRANSITIONAL CELL; CELL POLARITY; COCULTURE TECHNIQUES; HUMANS; LAB-ON-A-CHIP DEVICES; LACTIC ACID; MACROPHAGES; MICE; MICROFLUIDICS; RAW 264.7 CELLS; TUMOR MICROENVIRONMENT; URINARY BLADDER NEOPLASMS;

EID: 84948822863     PISSN: None     EISSN: 19492553     Source Type: Journal    
DOI: 10.18632/oncotarget.5538     Document Type: Article

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