Krüppel-like factor 4 overexpression initiates a mesenchymal-to-epithelial transition and redifferentiation of human pancreatic cells following expansion in long term adherent culture

PLoS ONE

Volumn 10, Issue 10, 2015, Pages

  Muir, Kenneth R ^a   Lima, Maria João ^a   Docherty, Hilary M ^a   McGowan, Neil W A ^b   Forbes, Shareen ^c   Heremans, Yves ^d   Forbes, Stuart J ^e   Heimberg, Harry ^d   Casey, John ^b   Docherty, Kevin ^a  

^a UNIVERSITY OF ABERDEEN   (United Kingdom)

^b UNIVERSITY OF EDINBURGH   (United Kingdom)

^c UNIVERSITY OF EDINBURGH   (United Kingdom)

^d DIABETES RESEARCH CENTER   (Belgium)

^e UNIVERSITY OF EDINBURGH   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

ADENOVIRUS VECTOR; INSULIN; KRUPPEL LIKE FACTOR 4; TRANSCRIPTION FACTOR; BIOLOGICAL MARKER; KRUPPEL LIKE FACTOR;

ADENOVIRUS INFECTION; ADIPOCYTE; APOPTOSIS; ARTICLE; CELL DIFFERENTIATION; CELL EXPANSION; CELL STRUCTURE; CHROMATIN STRUCTURE; CONTROLLED STUDY; DOWN REGULATION; EPITHELIAL MESENCHYMAL TRANSITION; FLUORESCENCE ACTIVATED CELL SORTING; HUMAN; HUMAN CELL; HUMAN CELL CULTURE; IMMUNOCYTOCHEMISTRY; MICROSCOPY; OSTEOCYTE; PANCREAS CELL; PANCREAS ISLET BETA CELL; PROTEIN EXPRESSION; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; TUNEL ASSAY; ADIPOGENESIS; BONE DEVELOPMENT; CELL COMMUNICATION; CELL CULTURE; CELL CULTURE TECHNIQUE; CELL LINEAGE; CELL TRANSDIFFERENTIATION; CYTOLOGY; GENE EXPRESSION; GENETICS; METABOLISM; PANCREAS; PANCREAS ISLET;

ADIPOGENESIS; BIOMARKERS; CELL COMMUNICATION; CELL CULTURE TECHNIQUES; CELL DIFFERENTIATION; CELL LINEAGE; CELL TRANSDIFFERENTIATION; CELLS, CULTURED; EPITHELIAL-MESENCHYMAL TRANSITION; GENE EXPRESSION; HUMANS; INSULIN-SECRETING CELLS; ISLETS OF LANGERHANS; KRUPPEL-LIKE TRANSCRIPTION FACTORS; OSTEOGENESIS; PANCREAS;

EID: 84948739193     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0140352     Document Type: Article

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