Redifferentiation of expanded human pancreatic β-cell-derived cells by inhibition of the NOTCH pathway

Journal of Biological Chemistry

Volumn 287, Issue 21, 2012, Pages 17269-17280

  Bar, Yael ^a   Russ, Holger A ^a   Sintov, Elad ^a   Anker Kitai, Leeat ^a   Knoller, Sarah ^a   Efrat, Shimon ^a  

^a TEL AVIV UNIVERSITY   (Israel)

Author keywords

[No Author keywords available]

Indexed keywords

CELL AGGREGATION; CELL DEDIFFERENTIATION; CELL EXPANSION; CELL FUNCTIONS; CELL REDIFFERENTIATION; CELL REPLACEMENT THERAPY; CELL REPLICATION; CELL-FATE; CHROMATIN STRUCTURE; COMBINED TREATMENT; CULTURE INITIATION; DIFFERENTIATING EFFECTS; EPIGENETIC ANALYSIS; EPITHELIAL-MESENCHYMAL TRANSITION; EX-VIVO; IN-VITRO; IN-VIVO ANALYSIS; NOTCH RECEPTOR; PANCREATIC ISLET; SERUM-FREE MEDIUM;

CELLS; GENES; INSULIN; TRANSCRIPTION;

CYTOLOGY;

INSULIN; NOTCH RECEPTOR; PROTEIN P57; SHORT HAIRPIN RNA; TRANSCRIPTION FACTOR HES 1;

ADULT; AGED; ANIMAL EXPERIMENT; ARTICLE; CELL AGGREGATION; CELL DIFFERENTIATION; CELL EXPANSION; CELL LABELING; CELL STIMULATION; CONTROLLED STUDY; CULTURE MEDIUM; DOWN REGULATION; FEMALE; HUMAN; HUMAN CELL; HYPERGLYCEMIA; IN VITRO STUDY; IN VIVO STUDY; MALE; MOUSE; NONHUMAN; NUCLEOTIDE SEQUENCE; PANCREAS ISLET BETA CELL; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN LOCALIZATION; PROTEIN TARGETING; REPRODUCIBILITY; RNA SEQUENCE; UPREGULATION;

ADOLESCENT; ADULT; BASIC HELIX-LOOP-HELIX TRANSCRIPTION FACTORS; CELL DEDIFFERENTIATION; CELL PROLIFERATION; CELLS, CULTURED; EPIGENESIS, GENETIC; EPITHELIAL-MESENCHYMAL TRANSITION; FEMALE; GENE EXPRESSION REGULATION; HOMEODOMAIN PROTEINS; HUMANS; INSULIN; INSULIN-SECRETING CELLS; MALE; MIDDLE AGED; RECEPTORS, NOTCH; SIGNAL TRANSDUCTION;

MUS;

EID: 84861216975     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M111.319152     Document Type: Article

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