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Volumn 37, Issue 5, 2016, Pages 6143-6153

Nuclear PARP1 expression and its prognostic significance in breast cancer patients

Author keywords

BRCA1; Breast cancer; Immunohistochemistry; PARP1; Prognostic marker

Indexed keywords

BRCA1 PROTEIN; EPIDERMAL GROWTH FACTOR RECEPTOR 2; ESTROGEN RECEPTOR; NICOTINAMIDE ADENINE DINUCLEOTIDE ADENOSINE DIPHOSPHATE RIBOSYLTRANSFERASE 1; TUMOR MARKER;

EID: 84948707108     PISSN: 10104283     EISSN: 14230380     Source Type: Journal    
DOI: 10.1007/s13277-015-4465-0     Document Type: Article
Times cited : (32)

References (51)
  • 1
    • 84872853140 scopus 로고    scopus 로고
    • Global estimates of cancer prevalence for 27 sites in the adult population in 2008
    • COI: 1:CAS:528:DC%2BC38XhtV2itbfO, PID: 22752881
    • Bray F, Ren JS, Masuyer E, Ferlay J. Global estimates of cancer prevalence for 27 sites in the adult population in 2008. Int J Cancer. 2013;132:1133–45.
    • (2013) Int J Cancer , vol.132 , pp. 1133-1145
    • Bray, F.1    Ren, J.S.2    Masuyer, E.3    Ferlay, J.4
  • 2
    • 77949726422 scopus 로고    scopus 로고
    • Declining death rates reflect progress against cancer
    • PID: 20231893
    • Jemal A, Ward E, Thun M. Declining death rates reflect progress against cancer. PLoS One. 2010;5:e9584.
    • (2010) PLoS One , vol.5 , pp. e9584
    • Jemal, A.1    Ward, E.2    Thun, M.3
  • 3
    • 77951981110 scopus 로고    scopus 로고
    • Classification and prognosis of invasive breast cancer: from morphology to molecular taxonomy
    • PID: 20436504
    • Schnitt SJ. Classification and prognosis of invasive breast cancer: from morphology to molecular taxonomy. Mod Pathol. 2010;23:S60–4.
    • (2010) Mod Pathol , vol.23 , pp. S60-S64
    • Schnitt, S.J.1
  • 4
    • 33745867638 scopus 로고    scopus 로고
    • Poly(ADP-ribose): novel functions for an old molecule
    • COI: 1:CAS:528:DC%2BD28Xms1Ohsb4%3D, PID: 16829982
    • Schreiber V, Dantzer F, Ame JC, de Murcia G. Poly(ADP-ribose): novel functions for an old molecule. Nat Rev Mol Cell Biol. 2006;7:517–28.
    • (2006) Nat Rev Mol Cell Biol , vol.7 , pp. 517-528
    • Schreiber, V.1    Dantzer, F.2    Ame, J.C.3    de Murcia, G.4
  • 5
    • 84862758175 scopus 로고    scopus 로고
    • New insights into the molecular and cellular functions of poly(ADP-ribose) and PARPs
    • COI: 1:CAS:528:DC%2BC38XovVaht70%3D, PID: 22713970
    • Gibson BA, Kraus WL. New insights into the molecular and cellular functions of poly(ADP-ribose) and PARPs. Nat Rev Mol Cell Biol. 2012;13:411–24.
    • (2012) Nat Rev Mol Cell Biol , vol.13 , pp. 411-424
    • Gibson, B.A.1    Kraus, W.L.2
  • 6
  • 7
    • 77954274504 scopus 로고    scopus 로고
    • The PARP side of the nucleus: molecular actions, physiological outcomes, and clinical targets
    • COI: 1:CAS:528:DC%2BC3cXpsFejsr4%3D, PID: 20603072
    • Krishnakumar R, Kraus WL. The PARP side of the nucleus: molecular actions, physiological outcomes, and clinical targets. Mol Cell. 2010;39:8–24.
    • (2010) Mol Cell , vol.39 , pp. 8-24
    • Krishnakumar, R.1    Kraus, W.L.2
  • 8
    • 0036893150 scopus 로고    scopus 로고
    • The relationship between the roles of BRCA genes in DNA repair and cancer predisposition
    • COI: 1:CAS:528:DC%2BD38XptFGmu7o%3D, PID: 12470990
    • Tutt A, Ashworth A. The relationship between the roles of BRCA genes in DNA repair and cancer predisposition. Trends Mol Med. 2002;8:571–6.
    • (2002) Trends Mol Med , vol.8 , pp. 571-576
    • Tutt, A.1    Ashworth, A.2
  • 9
    • 67650471685 scopus 로고    scopus 로고
    • Inhibition of poly(ADP-ribose) polymerase in tumors from BRCA mutation carriers
    • COI: 1:CAS:528:DC%2BD1MXosVKrtrw%3D, PID: 19553641
    • Fong PC, Boss DS, Yap TA, Tutt A, Wu P, Mergui-Roelvink M, et al. Inhibition of poly(ADP-ribose) polymerase in tumors from BRCA mutation carriers. N Engl J Med. 2009;361:123–34.
    • (2009) N Engl J Med , vol.361 , pp. 123-134
    • Fong, P.C.1    Boss, D.S.2    Yap, T.A.3    Tutt, A.4    Wu, P.5    Mergui-Roelvink, M.6
  • 10
    • 79956195555 scopus 로고    scopus 로고
    • Novel agents and future directions for refractory breast cancer
    • COI: 1:CAS:528:DC%2BC3MXmtl2htbk%3D, PID: 21600381
    • Burstein HJ. Novel agents and future directions for refractory breast cancer. Semin Oncol. 2011;38:S17–24.
    • (2011) Semin Oncol , vol.38 , pp. S17-S24
    • Burstein, H.J.1
  • 11
    • 17244375049 scopus 로고    scopus 로고
    • Specific killing of BRCA2-deficient tumours with inhibitors of poly(ADP-ribose) polymerase
    • COI: 1:CAS:528:DC%2BD2MXjtFOmsrY%3D, PID: 15829966
    • Bryant HE, Schultz N, Thomas HD, Parker KM, Flower D, Lopez E, et al. Specific killing of BRCA2-deficient tumours with inhibitors of poly(ADP-ribose) polymerase. Nature. 2005;434:913–7.
    • (2005) Nature , vol.434 , pp. 913-917
    • Bryant, H.E.1    Schultz, N.2    Thomas, H.D.3    Parker, K.M.4    Flower, D.5    Lopez, E.6
  • 12
    • 0242298326 scopus 로고    scopus 로고
    • Lethal combinations
    • COI: 1:CAS:528:DC%2BD3sXosFWrsbw%3D, PID: 14593402
    • Tucker CL, Fields S. Lethal combinations. Nat Genet. 2003;35:204–5.
    • (2003) Nat Genet , vol.35 , pp. 204-205
    • Tucker, C.L.1    Fields, S.2
  • 13
    • 17244373777 scopus 로고    scopus 로고
    • Targeting the DNA repair defect in BRCA mutant cells as a therapeutic strategy
    • COI: 1:CAS:528:DC%2BD2MXjtFOmsrc%3D, PID: 15829967
    • Farmer H, McCabe N, Lord CJ, Tutt AN, Johnson DA, Richardson TB, et al. Targeting the DNA repair defect in BRCA mutant cells as a therapeutic strategy. Nature. 2005;434:917–21.
    • (2005) Nature , vol.434 , pp. 917-921
    • Farmer, H.1    McCabe, N.2    Lord, C.J.3    Tutt, A.N.4    Johnson, D.A.5    Richardson, T.B.6
  • 14
    • 77955019276 scopus 로고    scopus 로고
    • Oral poly(ADP-ribose) polymerase inhibitor olaparib in patients with BRCA1 or BRCA2 mutations and advanced breast cancer: a proof-of-concept trial
    • COI: 1:CAS:528:DC%2BC3cXpt1KktLc%3D, PID: 20609467
    • Tutt A, Robson M, Garber JE, Domchek SM, Audeh MW, Weitzel JN, et al. Oral poly(ADP-ribose) polymerase inhibitor olaparib in patients with BRCA1 or BRCA2 mutations and advanced breast cancer: a proof-of-concept trial. Lancet. 2010;376:235–44.
    • (2010) Lancet , vol.376 , pp. 235-244
    • Tutt, A.1    Robson, M.2    Garber, J.E.3    Domchek, S.M.4    Audeh, M.W.5    Weitzel, J.N.6
  • 15
    • 84859523588 scopus 로고    scopus 로고
    • Olaparib maintenance therapy in platinum-sensitive relapsed ovarian cancer
    • COI: 1:CAS:528:DC%2BC38XlslOrsLw%3D, PID: 22452356
    • Ledermann J, Harter P, Gourley C, Friedlander M, Vergote I, Rustin G, et al. Olaparib maintenance therapy in platinum-sensitive relapsed ovarian cancer. N Engl J Med. 2012;366:1382–92.
    • (2012) N Engl J Med , vol.366 , pp. 1382-1392
    • Ledermann, J.1    Harter, P.2    Gourley, C.3    Friedlander, M.4    Vergote, I.5    Rustin, G.6
  • 16
    • 84925270121 scopus 로고    scopus 로고
    • An update on PARP inhibitors--moving to the adjuvant setting
    • COI: 1:CAS:528:DC%2BC2cXhslCis7jN, PID: 25286972
    • Sonnenblick A, de Azambuja E, Azim Jr HA, Piccart M. An update on PARP inhibitors--moving to the adjuvant setting. Nat Rev Clin Oncol. 2015;12:27–41.
    • (2015) Nat Rev Clin Oncol , vol.12 , pp. 27-41
    • Sonnenblick, A.1    de Azambuja, E.2    Azim, H.A.3    Piccart, M.4
  • 17
    • 77956224281 scopus 로고    scopus 로고
    • Iniparib, a PARP1 inhibitor for the potential treatment of cancer, including triple-negative breast cancer
    • COI: 1:CAS:528:DC%2BC3cXhtlGjurbE, PID: 20799148
    • Liang H, Tan AR. Iniparib, a PARP1 inhibitor for the potential treatment of cancer, including triple-negative breast cancer. IDrugs. 2010;13:646–56.
    • (2010) IDrugs , vol.13 , pp. 646-656
    • Liang, H.1    Tan, A.R.2
  • 19
    • 84880777712 scopus 로고    scopus 로고
    • The poly(ADP-ribose) polymerase inhibitor niraparib (MK4827) in BRCA mutation carriers and patients with sporadic cancer: a phase 1 dose-escalation trial
    • COI: 1:CAS:528:DC%2BC3sXhtVOjtLnF, PID: 23810788
    • Sandhu SK, Schelman WR, Wilding G, Moreno V, Baird RD, Miranda S, et al. The poly(ADP-ribose) polymerase inhibitor niraparib (MK4827) in BRCA mutation carriers and patients with sporadic cancer: a phase 1 dose-escalation trial. Lancet Oncol. 2013;14:882–92.
    • (2013) Lancet Oncol , vol.14 , pp. 882-892
    • Sandhu, S.K.1    Schelman, W.R.2    Wilding, G.3    Moreno, V.4    Baird, R.D.5    Miranda, S.6
  • 20
    • 84898020932 scopus 로고    scopus 로고
    • Beyond breast and ovarian cancers: PARP inhibitors for BRCA mutation-associated and BRCA-like solid tumors
    • PID: 24616882
    • O’Sullivan CC, Moon DH, Kohn EC, Lee JM. Beyond breast and ovarian cancers: PARP inhibitors for BRCA mutation-associated and BRCA-like solid tumors. Front Oncol. 2014;4:42.
    • (2014) Front Oncol , vol.4 , pp. 42
    • O’Sullivan, C.C.1    Moon, D.H.2    Kohn, E.C.3    Lee, J.M.4
  • 21
    • 84921771510 scopus 로고    scopus 로고
    • Olaparib monotherapy in patients with advanced cancer and a germline BRCA1/2 mutation
    • COI: 1:CAS:528:DC%2BC2MXjsVWrsLY%3D, PID: 25366685
    • Kaufman B, Shapira-Frommer R, Schmutzler RK, Audeh MW, Friedlander M, Balmaña J, et al. Olaparib monotherapy in patients with advanced cancer and a germline BRCA1/2 mutation. J Clin Oncol. 2015;33:244–50.
    • (2015) J Clin Oncol , vol.33 , pp. 244-250
    • Kaufman, B.1    Shapira-Frommer, R.2    Schmutzler, R.K.3    Audeh, M.W.4    Friedlander, M.5    Balmaña, J.6
  • 22
    • 33748065304 scopus 로고    scopus 로고
    • Deficiency in the repair of DNA damage by homologous recombination and sensitivity to poly(ADP-ribose) polymerase inhibition
    • COI: 1:CAS:528:DC%2BD28XotFWqtLg%3D, PID: 16912188
    • McCabe N, Turner NC, Lord CJ, Kluzek K, Bialkowska A, Swift S, et al. Deficiency in the repair of DNA damage by homologous recombination and sensitivity to poly(ADP-ribose) polymerase inhibition. Cancer Res. 2006;66:8109–15.
    • (2006) Cancer Res , vol.66 , pp. 8109-8115
    • McCabe, N.1    Turner, N.C.2    Lord, C.J.3    Kluzek, K.4    Bialkowska, A.5    Swift, S.6
  • 23
    • 79955454978 scopus 로고    scopus 로고
    • Exploiting the homologous recombination DNA repair network for targeted cancer therapy
    • PID: 21603316
    • Peng G, Lin SY. Exploiting the homologous recombination DNA repair network for targeted cancer therapy. World J Clin Oncol. 2011;2:73–9.
    • (2011) World J Clin Oncol , vol.2 , pp. 73-79
    • Peng, G.1    Lin, S.Y.2
  • 24
    • 84903547236 scopus 로고    scopus 로고
    • Olaparib maintenance therapy in patients with platinum-sensitive relapsed serous ovarian cancer: a preplanned retrospective analysis of outcomes by BRCA status in a randomised phase 2 trial
    • COI: 1:CAS:528:DC%2BC2cXhtVWrsrrK, PID: 24882434
    • Ledermann J, Harter P, Gourley C, Friedlander M, Vergote I, Rustin G, et al. Olaparib maintenance therapy in patients with platinum-sensitive relapsed serous ovarian cancer: a preplanned retrospective analysis of outcomes by BRCA status in a randomised phase 2 trial. Lancet Oncol. 2014;15:852–61.
    • (2014) Lancet Oncol , vol.15 , pp. 852-861
    • Ledermann, J.1    Harter, P.2    Gourley, C.3    Friedlander, M.4    Vergote, I.5    Rustin, G.6
  • 25
    • 84858198901 scopus 로고    scopus 로고
    • Failure of iniparib to inhibit poly(ADP-ribose) polymerase in vitro
    • COI: 1:CAS:528:DC%2BC38XktVynu7k%3D, PID: 22291137
    • Patel AG, De Lorenzo SB, Flatten KS, Poirier GG, Kaufmann SH. Failure of iniparib to inhibit poly(ADP-ribose) polymerase in vitro. Clin Cancer Res. 2012;18:1655–62.
    • (2012) Clin Cancer Res , vol.18 , pp. 1655-1662
    • Patel, A.G.1    De Lorenzo, S.B.2    Flatten, K.S.3    Poirier, G.G.4    Kaufmann, S.H.5
  • 26
    • 84872971914 scopus 로고    scopus 로고
    • Secondary mutations in BRCA2 associated with clinical resistance to a PARP inhibitor
    • COI: 1:CAS:528:DC%2BC3sXhsFeqsLg%3D, PID: 23165508
    • Barber LJ, Sandhu S, Chen L, Campbell J, Kozarewa I, Fenwick K, et al. Secondary mutations in BRCA2 associated with clinical resistance to a PARP inhibitor. J Pathol. 2013;229:422–9.
    • (2013) J Pathol , vol.229 , pp. 422-429
    • Barber, L.J.1    Sandhu, S.2    Chen, L.3    Campbell, J.4    Kozarewa, I.5    Fenwick, K.6
  • 27
    • 84872837247 scopus 로고    scopus 로고
    • Loss of 53BP1 causes PARP inhibitor resistance in Brca1-mutated mouse mammary tumors
    • COI: 1:CAS:528:DC%2BC3sXotl2ksw%3D%3D, PID: 23103855
    • Jaspers JE, Kersbergen A, Boon U, Sol W, van Deemter L, Zander SA, et al. Loss of 53BP1 causes PARP inhibitor resistance in Brca1-mutated mouse mammary tumors. Cancer Discov. 2013;3:68–81.
    • (2013) Cancer Discov , vol.3 , pp. 68-81
    • Jaspers, J.E.1    Kersbergen, A.2    Boon, U.3    Sol, W.4    van Deemter, L.5    Zander, S.A.6
  • 28
    • 79952852791 scopus 로고    scopus 로고
    • Upregulation of Poly (ADP-Ribose) Polymerase-1 (PARP1) in triple-negative breast cancer and other primary human tumor types
    • COI: 1:CAS:528:DC%2BC3cXhsFKnsbrE, PID: 21779467
    • Ossovskaya V, Koo IC, Kaldjian EP, Alvares C, Sherman BM. Upregulation of Poly (ADP-Ribose) Polymerase-1 (PARP1) in triple-negative breast cancer and other primary human tumor types. Genes Cancer. 2010;1:812–21.
    • (2010) Genes Cancer , vol.1 , pp. 812-821
    • Ossovskaya, V.1    Koo, I.C.2    Kaldjian, E.P.3    Alvares, C.4    Sherman, B.M.5
  • 29
    • 73449100129 scopus 로고    scopus 로고
    • Inhibition of poly adenosine diphosphate-ribose polymerase decreases hepatocellular carcinoma growth by modulation of tumor-related gene expression
    • COI: 1:CAS:528:DC%2BC3cXhsVCqurc%3D, PID: 20034026
    • Quiles-Perez R, Muñoz-Gámez JA, Ruiz-Extremera A, O’Valle F, Sanjuán-Nuñez L, Martín-Alvarez AB, et al. Inhibition of poly adenosine diphosphate-ribose polymerase decreases hepatocellular carcinoma growth by modulation of tumor-related gene expression. Hepatology. 2010;51:255–66.
    • (2010) Hepatology , vol.51 , pp. 255-266
    • Quiles-Perez, R.1    Muñoz-Gámez, J.A.2    Ruiz-Extremera, A.3    O’Valle, F.4    Sanjuán-Nuñez, L.5    Martín-Alvarez, A.B.6
  • 30
    • 84892641981 scopus 로고    scopus 로고
    • Poly (ADP-ribose) polymerase 1 protein expression in normal and neoplastic prostatic tissue
    • COI: 1:STN:280:DC%2BC3sjmtlGjtg%3D%3D, PID: 23807292
    • Salemi M, Galia A, Fraggetta F, La Corte C, Pepe P, La Vignera S, et al. Poly (ADP-ribose) polymerase 1 protein expression in normal and neoplastic prostatic tissue. Eur J Histochem. 2013;57:e13.
    • (2013) Eur J Histochem , vol.57 , pp. e13
    • Salemi, M.1    Galia, A.2    Fraggetta, F.3    La Corte, C.4    Pepe, P.5    La Vignera, S.6
  • 31
    • 79957940705 scopus 로고    scopus 로고
    • Cytoplasmic poly(adenosine diphosphate-ribose) polymerase expression is predictive and prognostic in patients with breast cancer treated with neoadjuvant chemotherapy
    • von Minckwitz G, Müller BM, Loibl S, Budczies J, Hanusch C, Darb-Esfahani S, et al. Cytoplasmic poly(adenosine diphosphate-ribose) polymerase expression is predictive and prognostic in patients with breast cancer treated with neoadjuvant chemotherapy. J Clin Oncol. 2011;29:2150–7.
    • (2011) J Clin Oncol , vol.29 , pp. 2150-2157
    • von Minckwitz, G.1    Müller, B.M.2    Loibl, S.3    Budczies, J.4    Hanusch, C.5    Darb-Esfahani, S.6
  • 32
    • 84858957528 scopus 로고    scopus 로고
    • Nuclear PARP-1 protein overexpression is associated with poor overall survival in early breast cancer
    • COI: 1:STN:280:DC%2BC38zlslSmtg%3D%3D, PID: 21908496
    • Rojo F, García-Parra J, Zazo S, Tusquets I, Ferrer-Lozano J, Menendez S, et al. Nuclear PARP-1 protein overexpression is associated with poor overall survival in early breast cancer. Ann Oncol. 2012;23:1156–64.
    • (2012) Ann Oncol , vol.23 , pp. 1156-1164
    • Rojo, F.1    García-Parra, J.2    Zazo, S.3    Tusquets, I.4    Ferrer-Lozano, J.5    Menendez, S.6
  • 33
    • 84908128145 scopus 로고    scopus 로고
    • Nuclear-cytoplasmic PARP-1 expression as an unfavorable prognostic marker in lymph node-negative early breast cancer: 15-year follow-up
    • PID: 24535158
    • Donizy P, Pietrzyk G, Halon A, Kozyra C, Gansukh T, Lage H, et al. Nuclear-cytoplasmic PARP-1 expression as an unfavorable prognostic marker in lymph node-negative early breast cancer: 15-year follow-up. Oncol Rep. 2014;31:1777–87.
    • (2014) Oncol Rep , vol.31 , pp. 1777-1787
    • Donizy, P.1    Pietrzyk, G.2    Halon, A.3    Kozyra, C.4    Gansukh, T.5    Lage, H.6
  • 34
    • 84940206128 scopus 로고    scopus 로고
    • Expression of DNA damage response molecules PARP1, γH2AX, BRCA1, and BRCA2 predicts poor survival of breast carcinoma patients
    • PID: 26310369
    • Park SH, Noh SJ, Kim KM, Bae JS, Kwon KS, Jung SH, et al. Expression of DNA damage response molecules PARP1, γH2AX, BRCA1, and BRCA2 predicts poor survival of breast carcinoma patients. Transl Oncol. 2015;8:239–49.
    • (2015) Transl Oncol , vol.8 , pp. 239-249
    • Park, S.H.1    Noh, S.J.2    Kim, K.M.3    Bae, J.S.4    Kwon, K.S.5    Jung, S.H.6
  • 37
    • 0026072872 scopus 로고
    • Pathological prognostic factors in breast cancer. I. The value of histological grade in breast cancer: experience from a large study with long-term follow-up
    • COI: 1:STN:280:DyaK38%2FpvVSltw%3D%3D, PID: 1757079
    • Elston CW, Ellis IO. Pathological prognostic factors in breast cancer. I. The value of histological grade in breast cancer: experience from a large study with long-term follow-up. Histopathology. 1991;19:403–10.
    • (1991) Histopathology , vol.19 , pp. 403-410
    • Elston, C.W.1    Ellis, I.O.2
  • 38
    • 79955738892 scopus 로고    scopus 로고
    • PARP-1 expression in breast cancer including BRCA1-associated, triple negative and basal-like tumors: possible implications for PARP-1 inhibitor therapy
    • COI: 1:CAS:528:DC%2BC3MXmtlyrs74%3D, PID: 21409392
    • Domagala P, Huzarski T, Lubinski J, Gugala K, Domagala W. PARP-1 expression in breast cancer including BRCA1-associated, triple negative and basal-like tumors: possible implications for PARP-1 inhibitor therapy. Breast Cancer Res Treat. 2011;127:861–9.
    • (2011) Breast Cancer Res Treat , vol.127 , pp. 861-869
    • Domagala, P.1    Huzarski, T.2    Lubinski, J.3    Gugala, K.4    Domagala, W.5
  • 39
    • 84939423024 scopus 로고    scopus 로고
    • Tailoring therapies-improving the management of early breast cancer: St Gallen international expert consensus on the primary therapy of early breast cancer 2015
    • COI: 1:STN:280:DC%2BC2MfgsFWrsw%3D%3D, PID: 25939896
    • Coates AS, Winer EP, Goldhirsch A, Gelber RD, Gnant M, Piccart-Gebhart M, et al. Tailoring therapies-improving the management of early breast cancer: St Gallen international expert consensus on the primary therapy of early breast cancer 2015. Ann Oncol. 2015;26:1533–46.
    • (2015) Ann Oncol , vol.26 , pp. 1533-1546
    • Coates, A.S.1    Winer, E.P.2    Goldhirsch, A.3    Gelber, R.D.4    Gnant, M.5    Piccart-Gebhart, M.6
  • 40
    • 33846568336 scopus 로고    scopus 로고
    • American society of Clinical Oncology/College of American Pathologists guideline recommendations for human epidermal growth factor receptor 2 testing in breast cancer
    • COI: 1:CAS:528:DC%2BD2sXhsVOmu74%3D
    • Wolff AC, Hammond ME, Schwartz JN, Hagerty KL, Allred DC, Cote RJ, et al. American society of Clinical Oncology/College of American Pathologists guideline recommendations for human epidermal growth factor receptor 2 testing in breast cancer. Pathol Lab Med. 2007;131:18–43.
    • (2007) Pathol Lab Med , vol.131 , pp. 18-43
    • Wolff, A.C.1    Hammond, M.E.2    Schwartz, J.N.3    Hagerty, K.L.4    Allred, D.C.5    Cote, R.J.6
  • 41
    • 84969973158 scopus 로고    scopus 로고
    • Therneau T. A package for survival analysis in S. 2013; R package version 2.37-4, http://CRAN.R-project.org/package=survival.
    • (2013) R package version , vol.2 , pp. 34-37
  • 42
    • 79955731161 scopus 로고    scopus 로고
    • Iniparib in metastatic triple-negative breast cancer
    • COI: 1:CAS:528:DC%2BC3MXlvFymtbs%3D, PID: 21542760, author reply 1781
    • Domagala P, Lubinski J, Domagala W. Iniparib in metastatic triple-negative breast cancer. N Engl J Med. 2011;364:1780. author reply 1781.
    • (2011) N Engl J Med , vol.364 , pp. 1780
    • Domagala, P.1    Lubinski, J.2    Domagala, W.3
  • 43
    • 83355174085 scopus 로고    scopus 로고
    • High nuclear poly(adenosine diphosphate-ribose) polymerase expression is predictive for BRCA1- and BRCA2-deficient breast cancer
    • PID: 22025145, author reply 4588
    • Ozretić L, Rhiem K, Huss S, Wappenschmidt B, Markiefka B, Sinn P, et al. High nuclear poly(adenosine diphosphate-ribose) polymerase expression is predictive for BRCA1- and BRCA2-deficient breast cancer. J Clin Oncol. 2011;29:4586–8. author reply 4588.
    • (2011) J Clin Oncol , vol.29 , pp. 4586-4588
    • Ozretić, L.1    Rhiem, K.2    Huss, S.3    Wappenschmidt, B.4    Markiefka, B.5    Sinn, P.6
  • 44
    • 10944227347 scopus 로고    scopus 로고
    • NAD+−dependent modulation of chromatin structure and transcription by nucleosome binding properties of PARP-1
    • COI: 1:CAS:528:DC%2BD2MXmsFyq, PID: 15607977
    • Kim MY, Mauro S, Gévry N, Lis JT, Kraus WL. NAD+−dependent modulation of chromatin structure and transcription by nucleosome binding properties of PARP-1. Cell. 2004;119:803–14.
    • (2004) Cell , vol.119 , pp. 803-814
    • Kim, M.Y.1    Mauro, S.2    Gévry, N.3    Lis, J.T.4    Kraus, W.L.5
  • 45
    • 84876531873 scopus 로고    scopus 로고
    • Poly(ADP-ribose) polymerase 1 is a key regulator of estrogen receptor α-dependent gene transcription
    • COI: 1:CAS:528:DC%2BC3sXmt12gsLw%3D, PID: 23493398
    • Zhang F, Wang Y, Wang L, Luo X, Huang K, Wang C, et al. Poly(ADP-ribose) polymerase 1 is a key regulator of estrogen receptor α-dependent gene transcription. J Biol Chem. 2013;288:11348–57.
    • (2013) J Biol Chem , vol.288 , pp. 11348-11357
    • Zhang, F.1    Wang, Y.2    Wang, L.3    Luo, X.4    Huang, K.5    Wang, C.6
  • 46
    • 84926228029 scopus 로고    scopus 로고
    • PARP1 and phospho-p65 protein expression is increased in human HER2-positive breast cancers
    • COI: 1:CAS:528:DC%2BC2MXlvFeksb0%3D, PID: 25833211
    • Stanley J, Klepczyk L, Keene K, Wei S, Li Y, Forero A, et al. PARP1 and phospho-p65 protein expression is increased in human HER2-positive breast cancers. Breast Cancer Res Treat. 2015;150:569–79.
    • (2015) Breast Cancer Res Treat , vol.150 , pp. 569-579
    • Stanley, J.1    Klepczyk, L.2    Keene, K.3    Wei, S.4    Li, Y.5    Forero, A.6
  • 47
    • 84866391539 scopus 로고    scopus 로고
    • HER2 overexpression renders human breast cancers sensitive to PARP inhibition independently of any defect in homologous recombination DNA repair
    • COI: 1:CAS:528:DC%2BC38XhtlygtbnM, PID: 22987487
    • Nowsheen S, Cooper T, Bonner JA, LoBuglio AF, Yang ES. HER2 overexpression renders human breast cancers sensitive to PARP inhibition independently of any defect in homologous recombination DNA repair. Cancer Res. 2012;72:4796–806.
    • (2012) Cancer Res , vol.72 , pp. 4796-4806
    • Nowsheen, S.1    Cooper, T.2    Bonner, J.A.3    LoBuglio, A.F.4    Yang, E.S.5
  • 48
    • 84969973125 scopus 로고    scopus 로고
    • Expression of proteins involved in DNA damage response in familial and sporadic breast cancer patients, Int J Cancer
    • Partipilo G, Simone G, Scattone A, Scarpi E, Azzariti A, Mangia A. Expression of proteins involved in DNA damage response in familial and sporadic breast cancer patients. Int J Cancer. 2015.
    • (2015) Mangia A
    • Partipilo, G.1    Simone, G.2    Scattone, A.3    Scarpi, E.4    Azzariti, A.5
  • 49
    • 84855698070 scopus 로고    scopus 로고
    • BRCAness profile of sporadic ovarian cancer predicts disease recurrence
    • COI: 1:CAS:528:DC%2BC38XhsVCqt7c%3D, PID: 22253870
    • Wysham WZ, Mhawech-Fauceglia P, Li H, Hays L, Syriac S, Skrepnik T, et al. BRCAness profile of sporadic ovarian cancer predicts disease recurrence. PLoS One. 2012;7:e30042.
    • (2012) PLoS One , vol.7 , pp. e30042
    • Wysham, W.Z.1    Mhawech-Fauceglia, P.2    Li, H.3    Hays, L.4    Syriac, S.5    Skrepnik, T.6
  • 50
    • 84915749291 scopus 로고    scopus 로고
    • PARP1-driven poly-ADP-ribosylation regulates BRCA1 function in homologous recombination-mediated DNA repair
    • COI: 1:CAS:528:DC%2BC2cXitVOhsbjO, PID: 25252691
    • Hu Y, Petit SA, Ficarro SB, Toomire KJ, Xie A, Lim E, et al. PARP1-driven poly-ADP-ribosylation regulates BRCA1 function in homologous recombination-mediated DNA repair. Cancer Discov. 2014;4:1430–47.
    • (2014) Cancer Discov , vol.4 , pp. 1430-1447
    • Hu, Y.1    Petit, S.A.2    Ficarro, S.B.3    Toomire, K.J.4    Xie, A.5    Lim, E.6
  • 51
    • 84915817765 scopus 로고    scopus 로고
    • A novel crosstalk between BRCA1 and poly (ADP-ribose) polymerase 1 in breast cancer
    • COI: 1:CAS:528:DC%2BC2cXitFalsLjN, PID: 25485588
    • Li D, Bi FF, Chen NN, Cao JM, Sun WP, Zhou YM, et al. A novel crosstalk between BRCA1 and poly (ADP-ribose) polymerase 1 in breast cancer. Cell Cycle. 2014;13:3442–9.
    • (2014) Cell Cycle , vol.13 , pp. 3442-3449
    • Li, D.1    Bi, F.F.2    Chen, N.N.3    Cao, J.M.4    Sun, W.P.5    Zhou, Y.M.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.