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Volumn 149, Issue 2, 2015, Pages 353-362

Biological and clinical significance of PARP1 protein expression in breast cancer

Author keywords

Biology; BRCA1; Breast cancer; Clinical significance; DNA repair gene defects; PARP1

Indexed keywords

BRCA1 PROTEIN; CHECKPOINT KINASE 1; KU ANTIGEN; NICOTINAMIDE ADENINE DINUCLEOTIDE ADENOSINE DIPHOSPHATE RIBOSYLTRANSFERASE 1; PROTEIN PIAS GAMMA; RAD51 PROTEIN; TUMOR PROTEIN; UNCLASSIFIED DRUG; NICOTINAMIDE ADENINE DINUCLEOTIDE ADENOSINE DIPHOSPHATE RIBOSYLTRANSFERASE; PARP1 PROTEIN, HUMAN; TUMOR MARKER;

EID: 84925541094     PISSN: 01676806     EISSN: 15737217     Source Type: Journal    
DOI: 10.1007/s10549-014-3230-1     Document Type: Article
Times cited : (64)

References (34)
  • 1
    • 84856019858 scopus 로고    scopus 로고
    • The DNA damage response and cancer therapy
    • COI: 1:CAS:528:DC%2BC38Xps1GmsQ%3D%3D, PID: 22258607
    • Lord CJ, Ashworth A (2012) The DNA damage response and cancer therapy. Nature 481(7381):287–294
    • (2012) Nature , vol.481 , Issue.7381 , pp. 287-294
    • Lord, C.J.1    Ashworth, A.2
  • 2
    • 0035835481 scopus 로고    scopus 로고
    • Poly(APD-ribosyl)ation, a DNA damage-driven protein modification and regulator of genomic instability
    • COI: 1:CAS:528:DC%2BD3MXksVWrsg%3D%3D, PID: 11163101
    • Burkle A (2001) Poly(APD-ribosyl)ation, a DNA damage-driven protein modification and regulator of genomic instability. Cancer Lett 163(1):1–5
    • (2001) Cancer Lett , vol.163 , Issue.1 , pp. 1-5
    • Burkle, A.1
  • 3
    • 4344685333 scopus 로고    scopus 로고
    • The PARP superfamily
    • COI: 1:CAS:528:DC%2BD2cXnt1CqtLk%3D, PID: 15273990
    • Ame JC, Spenlehauer C, de Murcia G (2004) The PARP superfamily. BioEssays 26(8):882–893
    • (2004) BioEssays , vol.26 , Issue.8 , pp. 882-893
    • Ame, J.C.1    Spenlehauer, C.2    de Murcia, G.3
  • 4
    • 77954274504 scopus 로고    scopus 로고
    • The PARP side of the nucleus: molecular actions, physiological outcomes, and clinical targets
    • COI: 1:CAS:528:DC%2BC3cXpsFejsr4%3D, PID: 20603072
    • Krishnakumar R, Kraus WL (2010) The PARP side of the nucleus: molecular actions, physiological outcomes, and clinical targets. Mol Cell 39(1):8–24
    • (2010) Mol Cell , vol.39 , Issue.1 , pp. 8-24
    • Krishnakumar, R.1    Kraus, W.L.2
  • 5
    • 33745867638 scopus 로고    scopus 로고
    • Poly(ADP-ribose): novel functions for an old molecule
    • COI: 1:CAS:528:DC%2BD28Xms1Ohsb4%3D, PID: 16829982
    • Schreiber V et al (2006) Poly(ADP-ribose): novel functions for an old molecule. Nat Rev Mol Cell Biol 7(7):517–528
    • (2006) Nat Rev Mol Cell Biol , vol.7 , Issue.7 , pp. 517-528
    • Schreiber, V.1
  • 6
    • 84867082212 scopus 로고    scopus 로고
    • Synthetic lethal targeting of DNA double-strand break repair deficient cells by human apurinic/apyrimidinic endonuclease inhibitors
    • COI: 1:CAS:528:DC%2BC38XksFCkurc%3D, PID: 22377908
    • Sultana R et al (2012) Synthetic lethal targeting of DNA double-strand break repair deficient cells by human apurinic/apyrimidinic endonuclease inhibitors. Int J Cancer 131(10):2433–2444
    • (2012) Int J Cancer , vol.131 , Issue.10 , pp. 2433-2444
    • Sultana, R.1
  • 7
    • 84856316429 scopus 로고    scopus 로고
    • Defective homologous recombination in human cancers
    • COI: 1:CAS:528:DC%2BC38XhsVaitbg%3D, PID: 21715099
    • Cerbinskaite A et al (2012) Defective homologous recombination in human cancers. Cancer Treat Rev 38(2):89–100
    • (2012) Cancer Treat Rev , vol.38 , Issue.2 , pp. 89-100
    • Cerbinskaite, A.1
  • 8
    • 84858975438 scopus 로고    scopus 로고
    • Poly(ADP-ribose) polymerase (PARP): rationale, preclinical and clinical evidences of its inhibition as breast cancer treatment
    • COI: 1:CAS:528:DC%2BC38XksFWmt78%3D, PID: 22443171
    • Orlando L et al (2012) Poly(ADP-ribose) polymerase (PARP): rationale, preclinical and clinical evidences of its inhibition as breast cancer treatment. Expert Opin Ther Targets 16(Suppl 2):S83–S89
    • (2012) Expert Opin Ther Targets , vol.16 , pp. S83-S89
    • Orlando, L.1
  • 9
    • 77955019276 scopus 로고    scopus 로고
    • Oral poly(ADP-ribose) polymerase inhibitor olaparib in patients with BRCA1 or BRCA2 mutations and advanced breast cancer: a proof-of-concept trial
    • COI: 1:CAS:528:DC%2BC3cXpt1KktLc%3D, PID: 20609467
    • Tutt A et al (2010) Oral poly(ADP-ribose) polymerase inhibitor olaparib in patients with BRCA1 or BRCA2 mutations and advanced breast cancer: a proof-of-concept trial. Lancet 376(9737):235–244
    • (2010) Lancet , vol.376 , Issue.9737 , pp. 235-244
    • Tutt, A.1
  • 10
    • 0033214624 scopus 로고    scopus 로고
    • Cleavage of automodified poly(ADP-ribose) polymerase during apoptosis. Evidence for involvement of caspase-7
    • COI: 1:CAS:528:DyaK1MXmsFWgtbw%3D, PID: 10497198
    • Germain M et al (1999) Cleavage of automodified poly(ADP-ribose) polymerase during apoptosis. Evidence for involvement of caspase-7. J Biol Chem 274(40):28379–28384
    • (1999) J Biol Chem , vol.274 , Issue.40 , pp. 28379-28384
    • Germain, M.1
  • 11
    • 0036733355 scopus 로고    scopus 로고
    • The therapeutic potential of poly(ADP-ribose) polymerase inhibitors
    • COI: 1:CAS:528:DC%2BD38XotVSmsr8%3D, PID: 12223530
    • Virag L, Szabo C (2002) The therapeutic potential of poly(ADP-ribose) polymerase inhibitors. Pharmacol Rev 54(3):375–429
    • (2002) Pharmacol Rev , vol.54 , Issue.3 , pp. 375-429
    • Virag, L.1    Szabo, C.2
  • 12
    • 79952852791 scopus 로고    scopus 로고
    • Upregulation of poly(ADP-Ribose) polymerase-1 (PARP1) in triple-negative breast cancer and other primary human tumor types
    • COI: 1:CAS:528:DC%2BC3cXhsFKnsbrE, PID: 21779467
    • Ossovskaya V et al (2010) Upregulation of poly(ADP-Ribose) polymerase-1 (PARP1) in triple-negative breast cancer and other primary human tumor types. Genes Cancer 1(8):812–821
    • (2010) Genes Cancer , vol.1 , Issue.8 , pp. 812-821
    • Ossovskaya, V.1
  • 13
    • 73449100129 scopus 로고    scopus 로고
    • Inhibition of poly adenosine diphosphate-ribose polymerase decreases hepatocellular carcinoma growth by modulation of tumor-related gene expression
    • COI: 1:CAS:528:DC%2BC3cXhsVCqurc%3D, PID: 20034026
    • Quiles-Perez R et al (2010) Inhibition of poly adenosine diphosphate-ribose polymerase decreases hepatocellular carcinoma growth by modulation of tumor-related gene expression. Hepatology 51(1):255–266
    • (2010) Hepatology , vol.51 , Issue.1 , pp. 255-266
    • Quiles-Perez, R.1
  • 14
    • 33748105074 scopus 로고    scopus 로고
    • Overexpression of poly(ADP-ribose) polymerase-1 (PARP-1) in the early stage of colorectal carcinogenesis
    • COI: 1:CAS:528:DC%2BD28Xptlykt7g%3D, PID: 16809031
    • Nosho K et al (2006) Overexpression of poly(ADP-ribose) polymerase-1 (PARP-1) in the early stage of colorectal carcinogenesis. Eur J Cancer 42(14):2374–2381
    • (2006) Eur J Cancer , vol.42 , Issue.14 , pp. 2374-2381
    • Nosho, K.1
  • 15
    • 0031822837 scopus 로고    scopus 로고
    • Tissue microarrays for high-throughput molecular profiling of tumor specimens
    • COI: 1:CAS:528:DyaK1cXktlKntr8%3D, PID: 9662379
    • Kononen J et al (1998) Tissue microarrays for high-throughput molecular profiling of tumor specimens. Nat Med 4(7):844–847
    • (1998) Nat Med , vol.4 , Issue.7 , pp. 844-847
    • Kononen, J.1
  • 16
    • 0021707691 scopus 로고
    • Histochemical approaches to steroid receptor analyses
    • PID: 6400637
    • McCarty KS Jr, McCarty KS Sr (1984) Histochemical approaches to steroid receptor analyses. Semin Diagn Pathol 1(4):297–308
    • (1984) Semin Diagn Pathol , vol.1 , Issue.4 , pp. 297-308
    • McCarty, K.S.1    McCarty, K.S.2
  • 17
    • 84855464719 scopus 로고    scopus 로고
    • Prognostic value of proliferation assay in the luminal, HER2 positive and triple negative biological classes of breast cancer
    • Aleskandarany MA et al (2011) Prognostic value of proliferation assay in the luminal, HER2 positive and triple negative biological classes of breast cancer. Breast Cancer Res 14(1):R3
    • (2011) Breast Cancer Res , vol.14 , Issue.1 , pp. R3
    • Aleskandarany, M.A.1
  • 18
    • 65249104546 scopus 로고    scopus 로고
    • Triple-negative breast cancer: distinguishing between basal and nonbasal subtypes
    • COI: 1:CAS:528:DC%2BD1MXjvVWltbs%3D, PID: 19318481
    • Rakha EA et al (2009) Triple-negative breast cancer: distinguishing between basal and nonbasal subtypes. Clin Cancer Res 15(7):2302–2310
    • (2009) Clin Cancer Res , vol.15 , Issue.7 , pp. 2302-2310
    • Rakha, E.A.1
  • 19
    • 33846266252 scopus 로고    scopus 로고
    • Prognostic markers in triple-negative breast cancer
    • COI: 1:CAS:528:DC%2BD2sXhtVKrtLY%3D, PID: 17146782
    • Rakha EA et al (2007) Prognostic markers in triple-negative breast cancer. Cancer 109(1):25–32
    • (2007) Cancer , vol.109 , Issue.1 , pp. 25-32
    • Rakha, E.A.1
  • 20
    • 79955738892 scopus 로고    scopus 로고
    • PARP-1 expression in breast cancer including BRCA1-associated, triple negative and basal-like tumors: possible implications for PARP-1 inhibitor therapy
    • COI: 1:CAS:528:DC%2BC3MXmtlyrs74%3D, PID: 21409392
    • Domagala P et al (2011) PARP-1 expression in breast cancer including BRCA1-associated, triple negative and basal-like tumors: possible implications for PARP-1 inhibitor therapy. Breast Cancer Res Treat 127(3):861–869
    • (2011) Breast Cancer Res Treat , vol.127 , Issue.3 , pp. 861-869
    • Domagala, P.1
  • 21
    • 84880333946 scopus 로고    scopus 로고
    • Poly(adenosine diphosphate-ribose) polymerase expression in BRCA-proficient ovarian high-grade serous carcinoma; association with patient survival
    • COI: 1:CAS:528:DC%2BC3sXls1Sns7g%3D, PID: 23574784
    • Gan A et al (2013) Poly(adenosine diphosphate-ribose) polymerase expression in BRCA-proficient ovarian high-grade serous carcinoma; association with patient survival. Hum Pathol 44(8):1638–1647
    • (2013) Hum Pathol , vol.44 , Issue.8 , pp. 1638-1647
    • Gan, A.1
  • 22
    • 17244373777 scopus 로고    scopus 로고
    • Targeting the DNA repair defect in BRCA mutant cells as a therapeutic strategy
    • COI: 1:CAS:528:DC%2BD2MXjtFOmsrc%3D, PID: 15829967
    • Farmer H et al (2005) Targeting the DNA repair defect in BRCA mutant cells as a therapeutic strategy. Nature 434(7035):917–921
    • (2005) Nature , vol.434 , Issue.7035 , pp. 917-921
    • Farmer, H.1
  • 23
    • 33748065304 scopus 로고    scopus 로고
    • Deficiency in the repair of DNA damage by homologous recombination and sensitivity to poly(ADP-ribose) polymerase inhibition
    • COI: 1:CAS:528:DC%2BD28XotFWqtLg%3D, PID: 16912188
    • McCabe N et al (2006) Deficiency in the repair of DNA damage by homologous recombination and sensitivity to poly(ADP-ribose) polymerase inhibition. Cancer Res 66(16):8109–8115
    • (2006) Cancer Res , vol.66 , Issue.16 , pp. 8109-8115
    • McCabe, N.1
  • 24
    • 84858783762 scopus 로고    scopus 로고
    • Poly(ADP-ribose) polymerase inhibition: a new direction for BRCA and triple-negative breast cancer?
    • Plummer R (2010) Poly(ADP-ribose) polymerase inhibition: a new direction for BRCA and triple-negative breast cancer? Breast Cancer Res 13(4):218
    • (2010) Breast Cancer Res , vol.13 , Issue.4 , pp. 218
    • Plummer, R.1
  • 25
    • 17244375049 scopus 로고    scopus 로고
    • Specific killing of BRCA2-deficient tumours with inhibitors of poly(ADP-ribose) polymerase
    • COI: 1:CAS:528:DC%2BD2MXjtFOmsrY%3D, PID: 15829966
    • Bryant HE et al (2005) Specific killing of BRCA2-deficient tumours with inhibitors of poly(ADP-ribose) polymerase. Nature 434(7035):913–917
    • (2005) Nature , vol.434 , Issue.7035 , pp. 913-917
    • Bryant, H.E.1
  • 26
    • 61349116261 scopus 로고    scopus 로고
    • Poly(ADP-ribose) polymerase-1 down-regulates BRCA2 expression through the BRCA2 promoter
    • COI: 1:CAS:528:DC%2BD1cXhsFWnsrjM, PID: 18990703
    • Wang J et al (2008) Poly(ADP-ribose) polymerase-1 down-regulates BRCA2 expression through the BRCA2 promoter. J Biol Chem 283(52):36249–36256
    • (2008) J Biol Chem , vol.283 , Issue.52 , pp. 36249-36256
    • Wang, J.1
  • 27
    • 65949124480 scopus 로고    scopus 로고
    • Defective repair of oxidative dna damage in triple-negative breast cancer confers sensitivity to inhibition of poly(ADP-ribose) polymerase
    • COI: 1:CAS:528:DC%2BD1MXksV2ht7k%3D, PID: 19351835
    • Alli E et al (2009) Defective repair of oxidative dna damage in triple-negative breast cancer confers sensitivity to inhibition of poly(ADP-ribose) polymerase. Cancer Res 69(8):3589–3596
    • (2009) Cancer Res , vol.69 , Issue.8 , pp. 3589-3596
    • Alli, E.1
  • 28
    • 77957599220 scopus 로고    scopus 로고
    • Poly(ADP-Ribose) polymerase inhibition: “targeted” therapy for triple-negative breast cancer
    • COI: 1:CAS:528:DC%2BC3cXht1aktbjM, PID: 20858840
    • Anders CK et al (2010) Poly(ADP-Ribose) polymerase inhibition: “targeted” therapy for triple-negative breast cancer. Clin Cancer Res 16(19):4702–4710
    • (2010) Clin Cancer Res , vol.16 , Issue.19 , pp. 4702-4710
    • Anders, C.K.1
  • 29
    • 70449449452 scopus 로고    scopus 로고
    • A PAR-SUMOnious mechanism of NEMO activation
    • COI: 1:CAS:528:DC%2BD1MXhsFOlt7vE, PID: 19917242
    • McCool K, Miyamoto S (2009) A PAR-SUMOnious mechanism of NEMO activation. Mol Cell 36(3):349–350
    • (2009) Mol Cell , vol.36 , Issue.3 , pp. 349-350
    • McCool, K.1    Miyamoto, S.2
  • 30
    • 33847011050 scopus 로고    scopus 로고
    • Ku70 and poly(ADP-ribose) polymerase-1 competitively regulate beta-catenin and T-cell factor-4-mediated gene transactivation: possible linkage of DNA damage recognition and Wnt signaling
    • COI: 1:CAS:528:DC%2BD2sXht1yntLY%3D, PID: 17283121
    • Idogawa M et al (2007) Ku70 and poly(ADP-ribose) polymerase-1 competitively regulate beta-catenin and T-cell factor-4-mediated gene transactivation: possible linkage of DNA damage recognition and Wnt signaling. Cancer Res 67(3):911–918
    • (2007) Cancer Res , vol.67 , Issue.3 , pp. 911-918
    • Idogawa, M.1
  • 31
    • 83755224388 scopus 로고    scopus 로고
    • Ku counteracts mobilization of PARP1 and MRN in chromatin damaged with DNA double-strand breaks
    • COI: 1:CAS:528:DC%2BC3MXhs1Crt77I, PID: 21880593
    • Cheng Q et al (2011) Ku counteracts mobilization of PARP1 and MRN in chromatin damaged with DNA double-strand breaks. Nucleic Acids Res 39(22):9605–9619
    • (2011) Nucleic Acids Res , vol.39 , Issue.22 , pp. 9605-9619
    • Cheng, Q.1
  • 32
    • 33845317242 scopus 로고    scopus 로고
    • Apoptosis-inducing factor mediates poly(ADP-ribose) (PAR) polymer-induced cell death
    • COI: 1:CAS:528:DC%2BD28XhtlWitLzE, PID: 17116881
    • Yu SW et al (2006) Apoptosis-inducing factor mediates poly(ADP-ribose) (PAR) polymer-induced cell death. Proc Natl Acad Sci USA 103(48):18314–18319
    • (2006) Proc Natl Acad Sci USA , vol.103 , Issue.48 , pp. 18314-18319
    • Yu, S.W.1
  • 33
    • 84860325913 scopus 로고    scopus 로고
    • Inflammasome-activated caspase 7 cleaves PARP1 to enhance the expression of a subset of NF-kappaB target genes
    • COI: 1:CAS:528:DC%2BC38XltVaru78%3D, PID: 22464733
    • Erener S et al (2012) Inflammasome-activated caspase 7 cleaves PARP1 to enhance the expression of a subset of NF-kappaB target genes. Mol Cell 46(2):200–211
    • (2012) Mol Cell , vol.46 , Issue.2 , pp. 200-211
    • Erener, S.1
  • 34
    • 33847292843 scopus 로고    scopus 로고
    • Breast carcinoma with basal differentiation: a proposal for pathology definition based on basal cytokeratin expression
    • COI: 1:STN:280:DC%2BD2s3ktVCqtQ%3D%3D, PID: 17448018
    • Rakha EA et al (2007) Breast carcinoma with basal differentiation: a proposal for pathology definition based on basal cytokeratin expression. Histopathology 50(4):434–438
    • (2007) Histopathology , vol.50 , Issue.4 , pp. 434-438
    • Rakha, E.A.1


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