-
1
-
-
67650874081
-
Cancer statistics 2009
-
Jemal A, Siegel R, Ward E, Hao Y, Xu J, et al. (2009) Cancer statistics 2009. CA Cancer J Clin 59 (4): 225-49.
-
(2009)
CA Cancer J Clin
, vol.59
, Issue.4
, pp. 225-249
-
-
Jemal, A.1
Siegel, R.2
Ward, E.3
Hao, Y.4
Xu, J.5
-
2
-
-
77955911553
-
Personalizing therapy for ovarian cancer: BRCAness and beyond
-
Bast RC, Mills GB, (2010) Personalizing therapy for ovarian cancer: BRCAness and beyond. J Clin Oncol 28 (22): 3545-58.
-
(2010)
J Clin Oncol
, vol.28
, Issue.22
, pp. 3545-3558
-
-
Bast, R.C.1
Mills, G.B.2
-
3
-
-
0037403380
-
Improved survival in women with BRCA associated ovarian carcinoma
-
Cass I, Baldwin RL, Varkey T, Moslehi R, Narod SA, et al. (2003) Improved survival in women with BRCA associated ovarian carcinoma. Cancer 97: 2187-2195.
-
(2003)
Cancer
, vol.97
, pp. 2187-2195
-
-
Cass, I.1
Baldwin, R.L.2
Varkey, T.3
Moslehi, R.4
Narod, S.A.5
-
4
-
-
19744368302
-
Cancer of the ovary
-
Cannistra SA, (2004) Cancer of the ovary. N Engl J Med 351 (24): 2519-29.
-
(2004)
N Engl J Med
, vol.351
, Issue.24
, pp. 2519-2529
-
-
Cannistra, S.A.1
-
5
-
-
57149093237
-
"BRCAness" syndrome in ovarian cancer: A case-control study describing the clinical features and outcome of patients with epithelial ovarian cancer associated with BRCA1 and BRCA2 mutations
-
Tan DS, Rothermundt C, Thomas K, Bancroft E, Eeles R, et al. (2008) "BRCAness" syndrome in ovarian cancer: A case-control study describing the clinical features and outcome of patients with epithelial ovarian cancer associated with BRCA1 and BRCA2 mutations. J Clin Oncol 26 (34): 5530-6.
-
(2008)
J Clin Oncol
, vol.26
, Issue.34
, pp. 5530-5536
-
-
Tan, D.S.1
Rothermundt, C.2
Thomas, K.3
Bancroft, E.4
Eeles, R.5
-
6
-
-
77953653251
-
Converting cancer mutations into therapeutic opportunities
-
O'Brien T, Stokoe D, (2009) Converting cancer mutations into therapeutic opportunities. EMBO Mol Med 1 (6-7): 297-9.
-
(2009)
EMBO Mol Med
, vol.1
, Issue.6-7
, pp. 297-299
-
-
O'Brien, T.1
Stokoe, D.2
-
7
-
-
80052243196
-
The role of poly adenosisne diphosphate ribose polymerase inhibitors in breast and ovarian cancer: current status and future directions
-
Chioh F, Mitchell G, Lindeman GJ, Friedlander M, Scott CL, (2011) The role of poly adenosisne diphosphate ribose polymerase inhibitors in breast and ovarian cancer: current status and future directions. Asia-Pacific JCO 7: 197-211.
-
(2011)
Asia-Pacific JCO
, vol.7
, pp. 197-211
-
-
Chioh, F.1
Mitchell, G.2
Lindeman, G.J.3
Friedlander, M.4
Scott, C.L.5
-
8
-
-
77955894453
-
Gene Expression profile of BRCAness that correlates with responsiveness to chemotherapy and with outcome in patients with epithelial ovarian cancer
-
Kontationopoulos PA, Spentoz D, Karlan BY, Taniguchi T, Fountzilaz E, et al. (2010) Gene Expression profile of BRCAness that correlates with responsiveness to chemotherapy and with outcome in patients with epithelial ovarian cancer. J Clin Oncol 28: 3555-3561.
-
(2010)
J Clin Oncol
, vol.28
, pp. 3555-3561
-
-
Kontationopoulos, P.A.1
Spentoz, D.2
Karlan, B.Y.3
Taniguchi, T.4
Fountzilaz, E.5
-
9
-
-
67650471685
-
Inhibition of poly(ADP-ribose) polymerase in tumors from BRCA mutation carriers
-
Fong PC, Boss DS, Yap TA, Tutt A, Wu P, et al. (2009) Inhibition of poly(ADP-ribose) polymerase in tumors from BRCA mutation carriers. N Engl J Med 361 (2): 123-34.
-
(2009)
N Engl J Med
, vol.361
, Issue.2
, pp. 123-134
-
-
Fong, P.C.1
Boss, D.S.2
Yap, T.A.3
Tutt, A.4
Wu, P.5
-
10
-
-
68149161777
-
Phase II trial of the oral PARP inhibitor olaparib (AZD2281) in BRCA deficient advanced ovarian cancer
-
(suppl; abstr 5500)
-
Audeh MW, Penson RT, Friedlander M, et al. (2009) Phase II trial of the oral PARP inhibitor olaparib (AZD2281) in BRCA deficient advanced ovarian cancer. J Clin Oncol 27: 277s (suppl; abstr 5500).
-
(2009)
J Clin Oncol
, vol.27
-
-
Audeh, M.W.1
Penson, R.T.2
Friedlander, M.3
-
11
-
-
77955019276
-
Oral poly(ADP-ribose) polymerase inhibitor olaparib in patients with BRCA1 or BRCA2 mutations and advanced breast cancer: a proof-of-concept trial
-
Tutt A, Robson M, Garber JE, Domchek SM, Weitzel JN, et al. (2010) Oral poly(ADP-ribose) polymerase inhibitor olaparib in patients with BRCA1 or BRCA2 mutations and advanced breast cancer: a proof-of-concept trial. Lancet 376 (9737): 235-44.
-
(2010)
Lancet
, vol.376
, Issue.9737
, pp. 235-244
-
-
Tutt, A.1
Robson, M.2
Garber, J.E.3
Domchek, S.M.4
Weitzel, J.N.5
-
13
-
-
0031822837
-
Tissue microarrays for high-throughput molecular profiling of tumor specimens
-
Kononen J, Bubendorf L, Kallioniemi A, Barlund M, Schraml P, et al. (1998) Tissue microarrays for high-throughput molecular profiling of tumor specimens. Nat Med 4 (7): 844-7.
-
(1998)
Nat Med
, vol.4
, Issue.7
, pp. 844-847
-
-
Kononen, J.1
Bubendorf, L.2
Kallioniemi, A.3
Barlund, M.4
Schraml, P.5
-
14
-
-
0003496954
-
The statistical analysis of failure time data (2nd edition)
-
Hoboken, NJ
-
Kalbfleisch J, Prentice R, (2002) The statistical analysis of failure time data (2nd edition). Hoboken, NJ.
-
(2002)
-
-
Kalbfleisch, J.1
Prentice, R.2
-
15
-
-
57149093237
-
"BRCAness" syndrome in ovarian cancer: a case-control study describing the clinical features and outcome of patients with epithelial ovarian cancer associated with BRCA1 and BRCA2 mutations
-
Tan DS, Rothermundt C, Thomas K, (2008) "BRCAness" syndrome in ovarian cancer: a case-control study describing the clinical features and outcome of patients with epithelial ovarian cancer associated with BRCA1 and BRCA2 mutations. J Clin Oncol 26: 5530-6.
-
(2008)
J Clin Oncol
, vol.26
, pp. 5530-5536
-
-
Tan, D.S.1
Rothermundt, C.2
Thomas, K.3
-
16
-
-
77955886707
-
Somatic mutations in BRCA1 and BRCA2 could expand the number of patients that benefit from poly (ADP ribose) polymerase inhibitors in ovarian cancer
-
Hennessy BT, Timms KM, Carey MS, Gutin A, Meyer LA, et al. (2010) Somatic mutations in BRCA1 and BRCA2 could expand the number of patients that benefit from poly (ADP ribose) polymerase inhibitors in ovarian cancer. J Clin Oncol 28: 357-6.
-
(2010)
J Clin Oncol
, vol.28
, pp. 357-366
-
-
Hennessy, B.T.1
Timms, K.M.2
Carey, M.S.3
Gutin, A.4
Meyer, L.A.5
-
17
-
-
0038075462
-
Disruption of the Fanconi anemia-BRCA pathway in cisplatin-sensitive ovarian tumors
-
Taniguchi T, Tischkowitz M, Ameziane N, Hodgson SV, Mathew CG, et al. (2003) Disruption of the Fanconi anemia-BRCA pathway in cisplatin-sensitive ovarian tumors. Nat Med 9 (5): 568-74.
-
(2003)
Nat Med
, vol.9
, Issue.5
, pp. 568-574
-
-
Taniguchi, T.1
Tischkowitz, M.2
Ameziane, N.3
Hodgson, S.V.4
Mathew, C.G.5
-
18
-
-
33749465890
-
Cytogenetic instability in ovarian epithelial cells from women at risk of ovarian cancer
-
Pejovic T, Yates JE, Liu HY, Hays LE, Akkari Y, et al. (2006) Cytogenetic instability in ovarian epithelial cells from women at risk of ovarian cancer. Cancer Res 66: 9017-25.
-
(2006)
Cancer Res
, vol.66
, pp. 9017-9025
-
-
Pejovic, T.1
Yates, J.E.2
Liu, H.Y.3
Hays, L.E.4
Akkari, Y.5
-
19
-
-
34248184445
-
Fanconi anemia pathway-deficient tumor cells are hypersensitive to inhibition of ataxia telangiectasia mutated
-
Kennedy RD, Chen CC, Stuckert P, Archila EM, De la Vega MA, et al. (2007) Fanconi anemia pathway-deficient tumor cells are hypersensitive to inhibition of ataxia telangiectasia mutated. J Clin Invest 117 (5): 1440-9.
-
(2007)
J Clin Invest
, vol.117
, Issue.5
, pp. 1440-1449
-
-
Kennedy, R.D.1
Chen, C.C.2
Stuckert, P.3
Archila, E.M.4
de la Vega, M.A.5
-
20
-
-
77958606449
-
Sporadic breast carcinomas with somatic BRCA1 gene deletions share genotype/phenotype features with familial breast carcinomas
-
Rhiem K, Todt U, Wappenschmidt B, Klein A, Wardelmann E, et al. (2010) Sporadic breast carcinomas with somatic BRCA1 gene deletions share genotype/phenotype features with familial breast carcinomas. Anticancer Res 30 (9): 3445-9.
-
(2010)
Anticancer Res
, vol.30
, Issue.9
, pp. 3445-3449
-
-
Rhiem, K.1
Todt, U.2
Wappenschmidt, B.3
Klein, A.4
Wardelmann, E.5
-
21
-
-
77958049428
-
PTEN deficiency in endometrioid endometrial adenocarcinomas predicts sensitivity to PARP inhibitors
-
Dedes KJ, Wetterskog D, Mendes-Pereira AM, Natrajan R, Lambros MB, et al. (2010) PTEN deficiency in endometrioid endometrial adenocarcinomas predicts sensitivity to PARP inhibitors. Sci Transl Med 2 (53): 53ra75.
-
(2010)
Sci Transl Med
, vol.2
, Issue.53
-
-
Dedes, K.J.1
Wetterskog, D.2
Mendes-Pereira, A.M.3
Natrajan, R.4
Lambros, M.B.5
-
22
-
-
43049128529
-
Tenets of PTEN tumor suppression
-
Salmena L, Carracedo A, Pandolfi PP, (2008) Tenets of PTEN tumor suppression. Cell 133 (3): 403-14.
-
(2008)
Cell
, vol.133
, Issue.3
, pp. 403-414
-
-
Salmena, L.1
Carracedo, A.2
Pandolfi, P.P.3
-
23
-
-
34147121608
-
Poly(adenosine diphosphate-ribose) polymerase expression in serous ovarian carcinoma: correlation with p53, MIB-1, and outcome
-
Brustmann H, (2007) Poly(adenosine diphosphate-ribose) polymerase expression in serous ovarian carcinoma: correlation with p53, MIB-1, and outcome. Int J Gynecol Pathol 26 (2): 147-53.
-
(2007)
Int J Gynecol Pathol
, vol.26
, Issue.2
, pp. 147-153
-
-
Brustmann, H.1
-
24
-
-
79953141631
-
A structural bioinformatics approach to explore the interactions of P53 and BRCA1 gene products on ovarian and breast cancer
-
Parija S, Kumar A, (2011) A structural bioinformatics approach to explore the interactions of P53 and BRCA1 gene products on ovarian and breast cancer. Int J Bioinform Res Appl 7: 1-14.
-
(2011)
Int J Bioinform Res Appl
, vol.7
, pp. 1-14
-
-
Parija, S.1
Kumar, A.2
-
25
-
-
77957936036
-
The biological and clinical value of p53 expression in pelvic high-grade serous carcinomas
-
Köbel M, Reuss A, Bois A, Kommoss S, Kommoss F, et al. (2010) The biological and clinical value of p53 expression in pelvic high-grade serous carcinomas. J Pathol 2010 Oct, 222 (2): 191-8.
-
(2010)
J Pathol 2010 Oct
, Issue.2
, pp. 191-198
-
-
Köbel, M.1
Reuss, A.2
Bois, A.3
Kommoss, S.4
Kommoss, F.5
-
26
-
-
79956201393
-
Identification of BRCA-1 deficient ovarian cancers
-
Skytte A-B, Waldsterom M, Rasmussen AA, Cruger D, Woodward ER, et al. (2011) Identification of BRCA-1 deficient ovarian cancers. ACTA Ostet Gynecol 90: 593-599.25.
-
(2011)
ACTA Ostet Gynecol
, vol.90
, pp. 593-599
-
-
Skytte, A.-B.1
Waldsterom, M.2
Rasmussen, A.A.3
Cruger, D.4
Woodward, E.R.5
-
27
-
-
0032953384
-
Localization of human BRCA1 and its loss in high-grade, non-inherited breast carcinoma
-
Wilson CA, Ramos L, Villasenor MR, Anders KH, Press MF, et al. (1999) Localization of human BRCA1 and its loss in high-grade, non-inherited breast carcinoma. Nat genet 21: 236-240.
-
(1999)
Nat Genet
, vol.21
, pp. 236-240
-
-
Wilson, C.A.1
Ramos, L.2
Villasenor, M.R.3
Anders, K.H.4
Press, M.F.5
-
28
-
-
17844406861
-
BRCA1 Gene expression in breast cancer: A correlative study between real-time RT-PCR and immunohistochemistry
-
Al-Mulla, Abdulrahman M, Varadharaj G, Akhter N, Anim JT, (2005) BRCA1 Gene expression in breast cancer: A correlative study between real-time RT-PCR and immunohistochemistry. 53: 621-629.
-
(2005)
, vol.53
, pp. 621-629
-
-
Al-Mulla1
Abdulrahman, M.2
Varadharaj, G.3
Akhter, N.4
Anim, J.T.5
-
29
-
-
80155174280
-
Breast cancer 1 (BRCA1) protein expression as a prognostic marker in sporadic epithelial ovarian carcinoma: an NCIC CTG OV.16 correlative study
-
doi:10.1093/annonc/mdq770
-
Weberpals JI, Tu D, Squire JA, Amin MS, Islam S, et al. (2011) Breast cancer 1 (BRCA1) protein expression as a prognostic marker in sporadic epithelial ovarian carcinoma: an NCIC CTG OV.16 correlative study. Ann Oncol doi:10.1093/annonc/mdq770.
-
(2011)
Ann Oncol
-
-
Weberpals, J.I.1
Tu, D.2
Squire, J.A.3
Amin, M.S.4
Islam, S.5
-
30
-
-
80053600436
-
Aphase II trial of iniparib (BSI-201) in combination with gemcitibine/carboplatin (GC) in patients with platinum-resistant recurrent ovarian cancer
-
abstr 5005
-
Birrer MJ, Konstatinopoulos P, Penson RT, Roche M, Ambrosio A, et al. (2011) Aphase II trial of iniparib (BSI-201) in combination with gemcitibine/carboplatin (GC) in patients with platinum-resistant recurrent ovarian cancer. J Clin Oncol 29: suppl; abstr 5005.
-
(2011)
J Clin Oncol
, vol.29
, Issue.SUPPL.
-
-
Birrer, M.J.1
Konstatinopoulos, P.2
Penson, R.T.3
Roche, M.4
Ambrosio, A.5
-
31
-
-
33646582299
-
Chemosensitization to cisplatin by inhibitors of the Fanconi anemia/BRCA pathway
-
Chirnomas D, Taniguchi T, de la Vega M, Vaidya AP, Vasserman M, (2006) Chemosensitization to cisplatin by inhibitors of the Fanconi anemia/BRCA pathway. Mol Cancer Ther 2006 5: 952-61.
-
(2006)
Mol Cancer Ther 2006
, vol.5
, pp. 952-961
-
-
Chirnomas, D.1
Taniguchi, T.2
de la Vega, M.3
Vaidya, A.P.4
Vasserman, M.5
|