STAT-dependent upregulation of 12/15-lipoxygenase contributes to neuronal injury after stroke

Journal of Cerebral Blood Flow and Metabolism

Volumn 35, Issue 12, 2015, Pages 2043-2051

  Jung, Joo Eun ^a   Karatas, Hulya ^a   Liu, Yu ^a   Yalcin, Ayfer ^b,c   Montaner, Joan ^d   Lo, Eng H ^a   Van Leyen, Klaus ^a  

^a MASSACHUSETTS GENERAL HOSPITAL   (United States)

^b EGE UNIVERSITY   (Turkey)

^c BIRUNI UNIVERSITY   (Turkey)

^d HOSPITAL UNIVERSITARI VALL D HEBRON   (Spain)

Author keywords

ischemia; lipoxygenase; neuron; STAT; transcription factor

Indexed keywords

ARACHIDONATE 12 LIPOXYGENASE; ARACHIDONATE 15 LIPOXYGENASE; SMALL INTERFERING RNA; STAT1 PROTEIN; STAT6 PROTEIN; GLUCOSE; STAT PROTEIN;

ADULT; AGED; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; APOPTOSIS; ARTICLE; BRAIN INJURY; CELL DEATH; CEREBROVASCULAR ACCIDENT; CONTROLLED STUDY; EMBRYO; FEMALE; GENE EXPRESSION; HUMAN; HUMAN TISSUE; MALE; MIDDLE AGED; MOUSE; NERVE CELL; NONHUMAN; OXIDATIVE STRESS; PRIORITY JOURNAL; REOXYGENATION; UPREGULATION; ANIMAL; BIOSYNTHESIS; BRAIN HYPOXIA; C57BL MOUSE; DEFICIENCY; ENZYMOLOGY; GENE SILENCING; METABOLISM; PATHOLOGY; REPERFUSION INJURY;

AGED; ANIMALS; APOPTOSIS; ARACHIDONATE 12-LIPOXYGENASE; ARACHIDONATE 15-LIPOXYGENASE; FEMALE; GENE KNOCKDOWN TECHNIQUES; GLUCOSE; HUMANS; HYPOXIA, BRAIN; MALE; MICE; MICE, INBRED C57BL; MIDDLE AGED; NEURONS; OXIDATIVE STRESS; REPERFUSION INJURY; RNA, SMALL INTERFERING; STAT TRANSCRIPTION FACTORS; STROKE; UP-REGULATION;

EID: 84948675437     PISSN: 0271678X     EISSN: 15597016     Source Type: Journal    
DOI: 10.1038/jcbfm.2015.169     Document Type: Article

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