Pre-treatment of rats with ad-hepcidin prevents iron-induced oxidative stress in the brain

Free Radical Biology and Medicine

Volumn 90, Issue , 2016, Pages 126-132

  Gong, Jing ^a,c   Du, Fang ^b,c   Qian, Zhong Ming ^a,c   Luo, Qian Qian ^c   Sheng, Yuan ^c   Yung, Wing Ho ^b   Xu, Yan Xin ^a   Ke, Ya ^b  

^a EAST CHINA UNIVERSITY OF SCIENCE AND TECHNOLOGY   (China)

^b Prince of Wales Hospital   (Hong Kong)

^c FUDAN UNIVERSITY   (China)

Author keywords

Cortex; Hepcidin brain iron; Hippocampus; Iron overloaded rat; Reactive oxygen species (ROS); Striatum; Substantia nigra

Indexed keywords

8 ISOPROSTANE; HEPCIDIN; IRON; IRON DEXTRAN; REACTIVE OXYGEN METABOLITE; 2',7'-DICHLOROFLUORESCEIN; 8-EPI-PROSTAGLANDIN F2ALPHA; FLUORESCEIN DERIVATIVE; PROSTAGLANDIN F2 ALPHA; RECOMBINANT PROTEIN;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; ATOMIC ABSORPTION SPECTROMETRY; BRAIN REGION; CONTROLLED STUDY; CORPUS STRIATUM; HEK293 CELL LINE; HIPPOCAMPUS; IMMUNOFLUORESCENCE; IRON BLOOD LEVEL; IRON OVERLOAD; LATERAL BRAIN VENTRICLE; MALE; NONHUMAN; OXIDATIVE STRESS; PRIORITY JOURNAL; PROTEIN EXPRESSION; RAT; REAL TIME POLYMERASE CHAIN REACTION; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; SUBSTANTIA NIGRA; ANALOGS AND DERIVATIVES; ANIMAL; BRAIN; DRUG EFFECTS; METABOLISM; SPRAGUE DAWLEY RAT;

ANIMALS; BRAIN; DINOPROST; FLUORESCEINS; HEPCIDINS; IRON; IRON OVERLOAD; MALE; OXIDATIVE STRESS; RATS; RATS, SPRAGUE-DAWLEY; RECOMBINANT PROTEINS;

EID: 84948668687     PISSN: 08915849     EISSN: 18734596     Source Type: Journal    
DOI: 10.1016/j.freeradbiomed.2015.11.016     Document Type: Article

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