메뉴 건너뛰기




Volumn 247, Issue 2, 2006, Pages 173-179

Is ferroportin-hepcidin signaling altered in restless legs syndrome?

Author keywords

Basal ganglia disorders; Cerebrospinal fluid (CSF); Iron; Laser capture microdissection (LCM); Movement disorders; Neuromelanin; Putamen

Indexed keywords

HEPCIDIN; IRON; IRON BINDING PROTEIN; NEUROMELANIN;

EID: 33748433837     PISSN: 0022510X     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jns.2006.04.008     Document Type: Article
Times cited : (71)

References (35)
  • 1
    • 0037738587 scopus 로고    scopus 로고
    • Restless legs syndrome: diagnostic criteria, special considerations, and epidemiology. A report from the restless legs syndrome diagnosis and epidemiology workshop at the National Institutes of Health
    • Allen R.P., Picchietti D., Hening W.A., Trenkwalder C., Walters A.S., and Montplaisi J. Restless legs syndrome: diagnostic criteria, special considerations, and epidemiology. A report from the restless legs syndrome diagnosis and epidemiology workshop at the National Institutes of Health. Sleep Med 4 2 (2003) 101-119
    • (2003) Sleep Med , vol.4 , Issue.2 , pp. 101-119
    • Allen, R.P.1    Picchietti, D.2    Hening, W.A.3    Trenkwalder, C.4    Walters, A.S.5    Montplaisi, J.6
  • 3
    • 0034646434 scopus 로고    scopus 로고
    • Prevalence and risk factors of RLS in an elderly population: the MEMO study. Memory and Morbidity in Augsburg Elderly
    • Rothdach A.J., Trenkwalder C., Haberstock J., Keil U., and Berger K. Prevalence and risk factors of RLS in an elderly population: the MEMO study. Memory and Morbidity in Augsburg Elderly. Neurology 54 5 (2000) 1064-1068
    • (2000) Neurology , vol.54 , Issue.5 , pp. 1064-1068
    • Rothdach, A.J.1    Trenkwalder, C.2    Haberstock, J.3    Keil, U.4    Berger, K.5
  • 4
    • 0001936579 scopus 로고    scopus 로고
    • Defining the phenotype of the restless legs syndrome (RLS) using age-of-symptom-onset
    • Allen R.P., and Earley C.J. Defining the phenotype of the restless legs syndrome (RLS) using age-of-symptom-onset. Sleep Med 1 (2000) 11-19
    • (2000) Sleep Med , vol.1 , pp. 11-19
    • Allen, R.P.1    Earley, C.J.2
  • 5
    • 33748433935 scopus 로고    scopus 로고
    • Epidemiology, family patterns and genetics of restless legs syndrome in RLS Foundation Conference Washington, DC
    • Labuda M. Epidemiology, family patterns and genetics of restless legs syndrome in RLS Foundation Conference Washington, DC (1997)
    • (1997)
    • Labuda, M.1
  • 6
    • 0042626103 scopus 로고    scopus 로고
    • Neuropathological examination suggests impaired brain iron acquisition in restless legs syndrome
    • Connor J.R., Boyer P.J., Menzies S.L., Dellinger B., Allen R.P., Ondo W.G., et al. Neuropathological examination suggests impaired brain iron acquisition in restless legs syndrome. Neurology 61 (2003) 304-309
    • (2003) Neurology , vol.61 , pp. 304-309
    • Connor, J.R.1    Boyer, P.J.2    Menzies, S.L.3    Dellinger, B.4    Allen, R.P.5    Ondo, W.G.6
  • 7
    • 0035936633 scopus 로고    scopus 로고
    • MRI measurement of brain iron in patients with restless legs syndrome
    • Allen R.P., Barker P.B., Wehrl F., Song H.K., and Earley C.J. MRI measurement of brain iron in patients with restless legs syndrome. Neurology 56 2 (2001) 263-265
    • (2001) Neurology , vol.56 , Issue.2 , pp. 263-265
    • Allen, R.P.1    Barker, P.B.2    Wehrl, F.3    Song, H.K.4    Earley, C.J.5
  • 8
    • 31944437979 scopus 로고    scopus 로고
    • Ferritin subunits in CSF are decreased in restless legs syndrome
    • Clardy S., Earley C.J., Allen R.P., Beard J.L., and Connor J.R. Ferritin subunits in CSF are decreased in restless legs syndrome. J Lab Clin Med 147 2 (2006) 67-73
    • (2006) J Lab Clin Med , vol.147 , Issue.2 , pp. 67-73
    • Clardy, S.1    Earley, C.J.2    Allen, R.P.3    Beard, J.L.4    Connor, J.R.5
  • 9
    • 24644457548 scopus 로고    scopus 로고
    • CSF ferritin and restless legs syndrome: effects of different clinical phenotypes
    • Earley C., Connor J.R., Beard J.L., Clardy S.L., and Allen R.P. CSF ferritin and restless legs syndrome: effects of different clinical phenotypes. Sleep 28 9 (2005) 1069-1075
    • (2005) Sleep , vol.28 , Issue.9 , pp. 1069-1075
    • Earley, C.1    Connor, J.R.2    Beard, J.L.3    Clardy, S.L.4    Allen, R.P.5
  • 10
    • 15444362927 scopus 로고    scopus 로고
    • CSF iron, ferritin and transferrin levels in restless legs syndrome
    • Mizuno S., Mihara T., Miyaoka T., Inagaki T., and Horiguchi J. CSF iron, ferritin and transferrin levels in restless legs syndrome. J Sleep Res 14 1 (2005) 43-47
    • (2005) J Sleep Res , vol.14 , Issue.1 , pp. 43-47
    • Mizuno, S.1    Mihara, T.2    Miyaoka, T.3    Inagaki, T.4    Horiguchi, J.5
  • 11
    • 2342554293 scopus 로고    scopus 로고
    • Decreased transferrin receptor expression by neuromelanin cells in restless legs syndrome
    • Connor J.R., Wang X.S., Patton S.M., Menzies S.L., Troncoso J.C., Earley C.J., et al. Decreased transferrin receptor expression by neuromelanin cells in restless legs syndrome. Neurology 62 9 (2004) 1563-1567
    • (2004) Neurology , vol.62 , Issue.9 , pp. 1563-1567
    • Connor, J.R.1    Wang, X.S.2    Patton, S.M.3    Menzies, S.L.4    Troncoso, J.C.5    Earley, C.J.6
  • 12
    • 18944366215 scopus 로고    scopus 로고
    • Mechanisms of disease: the role of hepcidin in iron homeostasis - implications for hemochromatosis and other disorders
    • Pietrangelo A., and Trautwein C. Mechanisms of disease: the role of hepcidin in iron homeostasis - implications for hemochromatosis and other disorders. Nat Clin Pract Gastroenterol Hepatol 1 1 (2004) 39-45
    • (2004) Nat Clin Pract Gastroenterol Hepatol , vol.1 , Issue.1 , pp. 39-45
    • Pietrangelo, A.1    Trautwein, C.2
  • 13
    • 0141763608 scopus 로고    scopus 로고
    • Serum hepcidin in clinical specimens
    • Dallalio G., Fleury T., and Means R.T. Serum hepcidin in clinical specimens. Br J Haematol 122 6 (2003) 996-1000
    • (2003) Br J Haematol , vol.122 , Issue.6 , pp. 996-1000
    • Dallalio, G.1    Fleury, T.2    Means, R.T.3
  • 14
    • 0035902605 scopus 로고    scopus 로고
    • Lack of hepcidin gene expression and severe tissue iron overload in upstream stimulatory factor 2 (USF2) knockout mice
    • Nicolas G., Bennoun M., Devaux I., Beaumont C., Grandchamp B., Kahn A., et al. Lack of hepcidin gene expression and severe tissue iron overload in upstream stimulatory factor 2 (USF2) knockout mice. Proc Natl Acad Sci U S A (2001)
    • (2001) Proc Natl Acad Sci U S A
    • Nicolas, G.1    Bennoun, M.2    Devaux, I.3    Beaumont, C.4    Grandchamp, B.5    Kahn, A.6
  • 16
    • 0037111732 scopus 로고    scopus 로고
    • Inappropriate expression of hepcidin is associated with iron refractory anemia: implications for the anemia of chronic disease
    • Weinstein D.A., Roy C.N., Fleming M.D., Loda M.F., Wolfsdorf J.I., and Andrews N.C. Inappropriate expression of hepcidin is associated with iron refractory anemia: implications for the anemia of chronic disease. Blood 100 10 (2002) 3776-3781
    • (2002) Blood , vol.100 , Issue.10 , pp. 3776-3781
    • Weinstein, D.A.1    Roy, C.N.2    Fleming, M.D.3    Loda, M.F.4    Wolfsdorf, J.I.5    Andrews, N.C.6
  • 17
    • 14544298717 scopus 로고    scopus 로고
    • Hepcidin - a regulator of intestinal iron absorption and iron recycling by macrophages
    • Ganz T. Hepcidin - a regulator of intestinal iron absorption and iron recycling by macrophages. Best Pract Res Clin Haematol 18 2 (2005) 171-182
    • (2005) Best Pract Res Clin Haematol , vol.18 , Issue.2 , pp. 171-182
    • Ganz, T.1
  • 18
    • 2342510407 scopus 로고    scopus 로고
    • IL-6 mediates hypoferremia of inflammation by inducing the synthesis of the iron regulatory hormone hepcidin
    • Nemeth E., Rivera S., Gabayan V., Keller C., Taudorf S., Pedersen B.K., et al. IL-6 mediates hypoferremia of inflammation by inducing the synthesis of the iron regulatory hormone hepcidin. J Clin Invest 113 9 (2004) 1271-1276
    • (2004) J Clin Invest , vol.113 , Issue.9 , pp. 1271-1276
    • Nemeth, E.1    Rivera, S.2    Gabayan, V.3    Keller, C.4    Taudorf, S.5    Pedersen, B.K.6
  • 19
    • 20444413054 scopus 로고    scopus 로고
    • Deregulation of proteins involved in iron metabolism in hepcidin-deficient mice
    • Viatte L., Lesbordes-Brion J.C., Lou D.Q., Bennoun M., Nicolas G., Kahn A., et al. Deregulation of proteins involved in iron metabolism in hepcidin-deficient mice. Blood 105 12 (2005) 4861-4864
    • (2005) Blood , vol.105 , Issue.12 , pp. 4861-4864
    • Viatte, L.1    Lesbordes-Brion, J.C.2    Lou, D.Q.3    Bennoun, M.4    Nicolas, G.5    Kahn, A.6
  • 20
    • 0034733635 scopus 로고    scopus 로고
    • A novel mammalian iron-regulated protein involved in intracellular iron metabolism
    • Abboud S., and Haile D.J. A novel mammalian iron-regulated protein involved in intracellular iron metabolism. J Biol Chem 275 26 (2000) 19906-19912
    • (2000) J Biol Chem , vol.275 , Issue.26 , pp. 19906-19912
    • Abboud, S.1    Haile, D.J.2
  • 21
    • 0035474950 scopus 로고    scopus 로고
    • Recent advances in disorders of iron metabolism: mutations, mechanisms and modifiers
    • Roy C.N., and Andrews N.C. Recent advances in disorders of iron metabolism: mutations, mechanisms and modifiers. Hum Mol Genet 10 20 (2001) 2181-2186
    • (2001) Hum Mol Genet , vol.10 , Issue.20 , pp. 2181-2186
    • Roy, C.N.1    Andrews, N.C.2
  • 22
    • 0037174609 scopus 로고    scopus 로고
    • C/EBPalpha regulates hepatic transcription of hepcidin, an antimicrobial peptide and regulator of iron metabolism. Cross-talk between C/EBP pathway and iron metabolism
    • Courselaud B., Pigeon C., Inoue Y., Inoue J., Gonzalez F.J., Leroyer P., et al. C/EBPalpha regulates hepatic transcription of hepcidin, an antimicrobial peptide and regulator of iron metabolism. Cross-talk between C/EBP pathway and iron metabolism. J Biol Chem 277 43 (2002) 41163-41170
    • (2002) J Biol Chem , vol.277 , Issue.43 , pp. 41163-41170
    • Courselaud, B.1    Pigeon, C.2    Inoue, Y.3    Inoue, J.4    Gonzalez, F.J.5    Leroyer, P.6
  • 23
    • 13444252281 scopus 로고    scopus 로고
    • Iron release from macrophages after erythrophagocytosis is up-regulated by ferroportin 1 overexpression and down-regulated by hepcidin
    • Knutson M.D., Oukka M., Koss L.M., Aydemir F., and Wessling-Resnick M. Iron release from macrophages after erythrophagocytosis is up-regulated by ferroportin 1 overexpression and down-regulated by hepcidin. Proc Natl Acad Sci U S A 102 5 (2005) 1324-1328
    • (2005) Proc Natl Acad Sci U S A , vol.102 , Issue.5 , pp. 1324-1328
    • Knutson, M.D.1    Oukka, M.2    Koss, L.M.3    Aydemir, F.4    Wessling-Resnick, M.5
  • 24
    • 0142126132 scopus 로고    scopus 로고
    • Mechanisms of iron mediated regulation of the duodenal iron transporters divalent metal transporter 1 and ferroportin 1
    • Zoller H., Theurl I., Koch R., Kaser A., and Weiss G. Mechanisms of iron mediated regulation of the duodenal iron transporters divalent metal transporter 1 and ferroportin 1. Blood Cells Mol Diseases 29 3 (2002) 488-497
    • (2002) Blood Cells Mol Diseases , vol.29 , Issue.3 , pp. 488-497
    • Zoller, H.1    Theurl, I.2    Koch, R.3    Kaser, A.4    Weiss, G.5
  • 25
    • 10844258104 scopus 로고    scopus 로고
    • Hepcidin regulates cellular iron efflux by binding to ferroportin and inducing its internalization
    • Nemeth E., Tuttle MS., Powelson J., Vaughn M.B., Donovan A., Ward D.M., et al. Hepcidin regulates cellular iron efflux by binding to ferroportin and inducing its internalization. Science 306 5704 (2004) 2090-2093
    • (2004) Science , vol.306 , Issue.5704 , pp. 2090-2093
    • Nemeth, E.1    Tuttle, MS.2    Powelson, J.3    Vaughn, M.B.4    Donovan, A.5    Ward, D.M.6
  • 26
    • 10744219518 scopus 로고    scopus 로고
    • Expression of the iron transporter ferroportin in synaptic vesicles and the blood-brain barrier
    • Wu L.J., Leenders A.G., Cooperman S., Meyron-Holtz E., Smith S., Land W., et al. Expression of the iron transporter ferroportin in synaptic vesicles and the blood-brain barrier. Brain Res 1001 1-2 (2004) 108-117
    • (2004) Brain Res , vol.1001 , Issue.1-2 , pp. 108-117
    • Wu, L.J.1    Leenders, A.G.2    Cooperman, S.3    Meyron-Holtz, E.4    Smith, S.5    Land, W.6
  • 27
    • 0035892632 scopus 로고    scopus 로고
    • Distribution of divalent metal transporter 1 and metal transport protein 1 in the normal and Belgrade rat
    • Burdo J.R., Menzies S.L., Simpson I.A., Garrick L.M., Garrick M.D., Dolan K.G., et al. Distribution of divalent metal transporter 1 and metal transport protein 1 in the normal and Belgrade rat. J Neurosci Res 66 6 (2001) 1198-1207
    • (2001) J Neurosci Res , vol.66 , Issue.6 , pp. 1198-1207
    • Burdo, J.R.1    Menzies, S.L.2    Simpson, I.A.3    Garrick, L.M.4    Garrick, M.D.5    Dolan, K.G.6
  • 28
    • 0033961913 scopus 로고    scopus 로고
    • Transferrin and transferrin receptor function in brain barrier systems
    • Moos T., and Morgan E.H. Transferrin and transferrin receptor function in brain barrier systems. Cell Mol Neurobiol 20 1 (2000) 77-95
    • (2000) Cell Mol Neurobiol , vol.20 , Issue.1 , pp. 77-95
    • Moos, T.1    Morgan, E.H.2
  • 29
    • 33748417562 scopus 로고
    • Ceruloplasmin in human cerebrospinal fluid
    • Jensen K. Ceruloplasmin in human cerebrospinal fluid. Acta Neurol Scand 39 (1963) 237-241
    • (1963) Acta Neurol Scand , vol.39 , pp. 237-241
    • Jensen, K.1
  • 30
    • 0034102395 scopus 로고    scopus 로고
    • Abnormalities in CSF concentrations of ferritin and transferrin in restless legs syndrome
    • Earley C.J., Connor J.R., Beard J.L., Malecki E.A., Epstein D.K., and Allen R.P. Abnormalities in CSF concentrations of ferritin and transferrin in restless legs syndrome. Neurology 54 8 (2000) 1698-1700
    • (2000) Neurology , vol.54 , Issue.8 , pp. 1698-1700
    • Earley, C.J.1    Connor, J.R.2    Beard, J.L.3    Malecki, E.A.4    Epstein, D.K.5    Allen, R.P.6
  • 31
    • 0037405911 scopus 로고    scopus 로고
    • Iron deficiency alters iron regulatory protein and iron transport protein expression in the perinatal rat brain
    • Siddappa A.J., Rao R.B., Wobken J.D., Casperson K., Leibold E.A., Connor J.R., et al. Iron deficiency alters iron regulatory protein and iron transport protein expression in the perinatal rat brain. Pediatr Res 53 5 (2003) 800-807
    • (2003) Pediatr Res , vol.53 , Issue.5 , pp. 800-807
    • Siddappa, A.J.1    Rao, R.B.2    Wobken, J.D.3    Casperson, K.4    Leibold, E.A.5    Connor, J.R.6
  • 32
  • 33
    • 0036861639 scopus 로고    scopus 로고
    • Brain iron homeostasis
    • Moos T. Brain iron homeostasis. Dan Med Bull 49 4 (2002) 279-301
    • (2002) Dan Med Bull , vol.49 , Issue.4 , pp. 279-301
    • Moos, T.1
  • 34
    • 10844222807 scopus 로고    scopus 로고
    • Serum pro-hepcidin: measuring active hepcidin or a non-functional precursor?
    • Brookes M.J., Sharma N.K., Tselepis C., and Iqbal T.H. Serum pro-hepcidin: measuring active hepcidin or a non-functional precursor?. Gut 54 1 (2005) 169-170
    • (2005) Gut , vol.54 , Issue.1 , pp. 169-170
    • Brookes, M.J.1    Sharma, N.K.2    Tselepis, C.3    Iqbal, T.H.4
  • 35
    • 2342422913 scopus 로고    scopus 로고
    • Pro-hepcidin: expression and cell specific localisation in the liver and its regulation in hereditary haemochromatosis, chronic renal insufficiency, and renal anaemia
    • Kulaksiz H., Gehrke S.G., Janetzko A., Rost D., Bruckner T., Kallinowski B., et al. Pro-hepcidin: expression and cell specific localisation in the liver and its regulation in hereditary haemochromatosis, chronic renal insufficiency, and renal anaemia. Gut 53 5 (2004) 735-743
    • (2004) Gut , vol.53 , Issue.5 , pp. 735-743
    • Kulaksiz, H.1    Gehrke, S.G.2    Janetzko, A.3    Rost, D.4    Bruckner, T.5    Kallinowski, B.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.