Cancer stem cells and cell size: A causal link?

Seminars in Cancer Biology

Volumn 35, Issue , 2015, Pages 191-199

  Li, Qiuhui ^a   Rycaj, Kiera ^a   Chen, Xin ^a   Tang, Dean G ^a,b  

^a UNIVERSITY OF TEXAS   (United States)

^b TONGJI UNIVERSITY SCHOOL OF MEDICINE   (China)

Author keywords

Cancer; Cancer stem cells; Cell size; Stem cells

Indexed keywords

ADULT; CANCER STEM CELL; CELL ACTIVITY; CELL SIZE; DIFFERENTIATION; PHENOTYPE; PROGENY; ANIMAL; CELL DIFFERENTIATION; CELL PROLIFERATION; HUMAN; METABOLISM; NEOPLASMS; PATHOLOGY; SIGNAL TRANSDUCTION;

ANIMALS; CELL DIFFERENTIATION; CELL PROLIFERATION; CELL SIZE; HUMANS; NEOPLASMS; NEOPLASTIC STEM CELLS; PHENOTYPE; SIGNAL TRANSDUCTION;

EID: 84948657335     PISSN: 1044579X     EISSN: 10963650     Source Type: Journal    
DOI: 10.1016/j.semcancer.2015.07.002     Document Type: Review

References (73)

1. Lloyd A.C. The regulation of cell size. Cell 2013, 154:1194-1205.
2. Conlon I., Raff M. Size control in animal development. Cell 1999, 96:235-244.
3. Mortimer R.K., Johnston J.R. Life span of individual yeast cells. Nature 1959, 183:1751-1752.
4. Yang J., Dungrawala H., Hua H., Manukyan A., Abraham L., Lane W., et al. Cell size and growth rate are major determinants of replicative lifespan. Cell Cycle 2011, 10:144-155.
5. Phipps S.M., Berletch J.B., Andrews L.G., Tollefsbol T.O. Aging cell culture: methods and observations. Methods Mol. Biol. 2007, 371:9-19.
6. Coelho C.M., Leevers S.J. Do growth and cell division rates determine cell size in multicellular organisms?. J. Cell Sci. 2000, 113(Pt 17):2927-2934.
7. Stocker H., Hafen E. Genetic control of cell size. Curr. Opin. Genet. Dev. 2000, 10:529-535.
8. Hunt A.M. The Cell Cycle 1993, University Press, Oxford.
9. Zhang J., Del Aguila R., Schneider C., Schneider B.L. The importance of being big. J. Invest. Dermatol. 2005, 10:131-141.
10. Son S., Tzur A., Weng Y., Jorgensen P., Kim J., Kirschner M.W., et al. Direct observation of mammalian cell growth and size regulation. Nat. Methods 2012, 9:910-912.
11. Rouzaire-Dubois B., Malo M., Milandri J.B., Dubois J.M. Cell size-proliferation relationship in rat glioma cells. Glia 2004, 45:249-257.
12. Dolznig H., Grebien F., Sauer T., Beug H., Mullner E.W. Evidence for a size-sensing mechanism in animal cells. Nat. Cell Biol. 2004, 6:899-905.
13. Tzur A., Kafri R., LeBleu V.S., Lahav G., Kirschner M.W. Cell growth and size homeostasis in proliferating animal cells. Science 2009, 325:167-171.
14. Weissman I.L. Stem cells: units of development, units of regeneration, and units in evolution. Cell 2000, 100:157-168.
15. Matsuoka T., Tavassoli M. Electron microscopic identification of hemopoietic progenitor cells by exploiting their sugar-recognizing receptors using a newly developed minibead technique. Exp. Hematol. 1989, 17:326-329.
16. Radley J.M., Ellis S., Palatsides M., Williams B., Bertoncello I. Ultrastructure of primitive hematopoietic stem cells isolated using probes of functional status. Exp. Hematol. 1999, 27:365-369.
17. Berardi A.C., Wang A., Levine J.D., Lopez P., Scadden D.T. Functional isolation and characterization of human hematopoietic stem cells. Science 1995, 267:104-108.
18. Vacanti M.P., Roy A., Cortiella J., Bonassar L., Vacanti C.A. Identification and initial characterization of spore-like cells in adult mammals. J. Cell. Biochem. 2001, 80:455-460.
19. Young H.E., Duplaa C., Yost M.J., Henson N.L., Floyd J.A., Detmer K., et al. Clonogenic analysis reveals reserve stem cells in postnatal mammals. II. Pluripotent epiblastic-like stem cells. Anat. Rec. A 2004, 277:178-203.
20. Zuba-Surma E.K., Kucia M., Abdel-Latif A., Dawn B., Hall B., Singh R., et al. Morphological characterization of very small embryonic-like stem cells (VSELs) by ImageStream system analysis. J. Cell. Mol. Med. 2008, 12:292-303.
21. Virant-Klun I., Zech N., Rozman P., Vogler A., Cvjeticanin B., Klemenc P., et al. Putative stem cells with an embryonic character isolated from the ovarian surface epithelium of women with no naturally present follicles and oocytes. Differentiation 2008, 76:843-856.
22. Smith J.R., Pochampally R., Perry A., Hsu S.C., Prockop D.J. Isolation of a highly clonogenic and multipotential subfraction of adult stem cells from bone marrow stroma. Stem Cells 2004, 22:823-831.
23. Hung S.C., Chen N.J., Hsieh S.L., Li H., Ma H.L., Lo W.H. Isolation and characterization of size-sieved stem cells from human bone marrow. Stem Cells 2002, 20:249-258.
24. D'Ippolito G., Howard G.A., Roos B.A., Schiller P.C. Sustained stromal stem cell self-renewal and osteoblastic differentiation during aging. Rejuvenation Res. 2006, 9:10-19.
25. Gao F.B., Raff M. Cell size control and a cell-intrinsic maturation program in proliferating oligodendrocyte precursor cells. J. Cell Biol. 1997, 138:1367-1377.
26. Barrandon Y., Green H. Cell size as a determinant of the clone-forming ability of human keratinocytes. Proc. Natl. Acad. Sci. U. S. A. 1985, 82:5390-5394.
27. Angello J.C., Pendergrass W.R., Norwood T.H., Prothero J. Proliferative potential of human fibroblasts: an inverse dependence on cell size. J. Cell Physiol. 1987, 132:125-130.
28. Parsa R., Yang A., McKeon F., Green H. Association of p63 with proliferative potential in normal and neoplastic human keratinocytes. J. Invest. Dermatol. 1999, 113:1099-1105.
29. Dazard J.E., Piette J., Basset-Seguin N., Blanchard J.M., Gandarillas A. Switch from p53 to MDM2 as differentiating human keratinocytes lose their proliferative potential and increase in cellular size. Oncogene 2000, 19:3693-3705.
30. Tseng H., Green H. Association of basonuclin with ability of keratinocytes to multiply and with absence of terminal differentiation. J. Cell Biol. 1994, 126:495-506.
31. Watt F.M., Green H. Involucrin synthesis is correlated with cell size in human epidermal cultures. J. Cell Biol. 1981, 90:738-742.
32. De Paiva C.S., Pflugfelder S.C., Li D.Q. Cell size correlates with phenotype and proliferative capacity in human corneal epithelial cells. Stem Cells 2006, 24:368-375.
33. Banks-Schlegel S., Green H. Involucrin synthesis and tissue assembly by keratinocytes in natural and cultured human epithelia. J. Cell Biol. 1981, 90:732-737.
34. Gandarillas A., Davies D., Blanchard J.M. Normal and c-Myc-promoted human keratinocyte differentiation both occur via a novel cell cycle involving cellular growth and endoreplication. Oncogene 2000, 19:3278-3289.
35. Majore I., Moretti P., Hass R., Kasper C. Identification of subpopulations in mesenchymal stem cell-like cultures from human umbilical cord. Cell Commun. Signal. 2009, 7:6.
36. Hall S.R., Jiang Y., Leary E., Yavanian G., Eminli S., O'Neill D.W., et al. Identification and isolation of small CD44-negative mesenchymal stem/progenitor cells from human bone marrow using elutriation and polychromatic flow cytometry. Stem Cells Tranl. Med. 2013, 2:567-578.
37. Sharma S., Cabana R., Shariatmadar S., Krishan A. Cellular volume and marker expression in human peripheral blood apheresis stem cells. Cytometry A 2008, 73:160-167.
38. Ratajczak M.Z., Zuba-Surma E.K., Wysoczynski M., Wan W., Ratajczak J., Wojakowski W., et al. Hunt for pluripotent stem cell - regenerative medicine search for almighty cell. J. Autoimmun. 2008, 30:151-162.
39. Colter D.C., Class R., DiGirolamo C.M., Prockop D.J. Rapid expansion of recycling stem cells in cultures of plastic-adherent cells from human bone marrow. Proc. Natl. Acad. Sci. U. S. A. 2000, 97:3213-3218.
40. Corradetti B., Lange-Consiglio A., Barucca M., Cremonesi F., Bizzaro D. Size-sieved subpopulations of mesenchymal stem cells from intervascular and perivascular equine umbilical cord matrix. Cell Prolif. 2011, 44:330-342.
41. Katsube Y., Hirose M., Nakamura C., Ohgushi H. Correlation between proliferative activity and cellular thickness of human mesenchymal stem cells. Biochem. Biophys. Res. Commun. 2008, 368:256-260.
42. Kucia M., Reca R., Campbell F.R., Zuba-Surma E., Majka M., Ratajczak J., et al. A population of very small embryonic-like (VSEL) CXCR4(+)SSEA-1(+)Oct-4+ stem cells identified in adult bone marrow. Leukemia 2006, 20:857-869.
43. Kucia M., Halasa M., Wysoczynski M., Baskiewicz-Masiuk M., Moldenhawer S., Zuba-Surma E., et al. Morphological and molecular characterization of novel population of CXCR4+ SSEA-4+ Oct-4+ very small embryonic-like cells purified from human cord blood: preliminary report. Leukemia 2007, 21:297-303.
44. Ratajczak J., Wysoczynski M., Zuba-Surma E., Wan W., Kucia M., Yoder M.C., et al. Adult murine bone marrow-derived very small embryonic-like stem cells differentiate into the hematopoietic lineage after coculture over OP9 stromal cells. Exp. Hematol. 2011, 39:225-237.
45. Miyanishi M., Mori Y., Seita J., Chen J.Y., Karten S., Chan C.K., et al. Do pluripotent stem cells exist in adult mice as very small embryonic stem cells?. Stem Cell Rep. 2013, 1:198-208.
46. Machado H.L., Kittrell F.S., Edwards D., White A.N., Atkinson R.L., Rosen J.M., et al. Separation by cell size enriches for mammary stem cell repopulation activity. Stem Cell Transl. Med. 2013, 2:199-203.
47. Tang D.G. Understanding cancer stem cell heterogeneity and plasticity. Cell Res. 2012, 22:457-472.
48. Kreso A., Dick J.E. Evolution of the cancer stem cell model. Cell. Stem Cell 2014, 14:275-291.
49. Aravalli R.N., Behnan Sahin M., Cressman E.N., Steer C.J. Establishment and characterization of a unique 1 microm diameter liver-derived progenitor cell line. Biochem. Biophys. Res. Commun. 2010, 391:56-62.
50. Bortolomai I., Canevari S., Facetti I., De Cecco L., Castellano G., Zacchetti A., et al. Tumor initiating cells: development and critical characterization of a model derived from the A431 carcinoma cell line forming spheres in suspension. Cell Cycle 2010, 9:1194-1206.
51. Srivastava V.K., Nalbantoglu J. Flow cytometric characterization of the DAOY medulloblastoma cell line for the cancer stem-like phenotype. Cytometry A 2008, 73:940-948.
52. Zhang S., Mercado-Uribe I., Xing Z., Sun B., Kuang J., Liu J. Generation of cancer stem-like cells through the formation of polyploid giant cancer cells. Oncogene 2014, 33:116-128.
53. - cancer cells are similarly tumorigenic. Cancer Res. 2005, 65:6207-6219.
54. + prostate cancer cells from xenograft human tumors are enriched in tumorigenic and metastatic progenitor cells. Oncogene 2006, 25:1696-1708.
55. + cell population is enriched in tumor-initiating cells. Cancer Res. 2007, 67:6796-6805.
56. Tang D.G., et al. Prostate cancer stem/progenitor cells: identification, characterization, and implications. Mol. Carcinog. 2007, 46:1-14.
57. Li H.W., Chen X., Calhoun-Davis T., Claypool K., Tang D.G. PC3 Human prostate carcinoma cell holoclones contain self-renewing tumor-initiating cells. Cancer Res. 2008, 68:1820-1825.
58. Li H.W., et al. Methodologies in assaying prostate cancer stem cells. Methods Mol. Biol. 2009, 569:85-138.
59. Liu C., et al. The microRNA miR-34a inhibits prostate cancer stem cells and metastasis by directly repressing CD44. Nat. Med. 2011, 17:211-215.
60. -/lo prostate cancer cell population harbors self-renewing long-term tumor-propagating cells that resist castration. Cell. Stem Cell 2012, 10:556-569.
61. Jeter C.R., Yang T., Wang J., Chao H., Tang D.G. Nanog in cancer stem cells and tumor development: an update and outstanding questions. Stem Cells 2015, 33(8):2381-2390.
62. Laplante M. Sabatini DM. mTOR signaling in growth control and disease. Cell 2012, 149:274-293.
63. Li Q., Dang C.V. c-Myc overexpression uncouples DNA replication from mitosis. Mol Cell Biol 1999, 19:5339-5351.
64. Johnston L.A., Prober D.A., Edgar B.A., Eisenman R.N., Gallant P. Drosophila myc regulates cellular growth during development. Cell 1999, 98:779-790.
65. Iritani B.M., Eisenman R.N. c-Myc enhances protein synthesis and cell size during B lymphocyte development. Proc. Natl. Acad. Sci. U. S. A. 1999, 96:13180-13185.
66. Zanet J., Pibre S., Jacquet C., Ramirez A., de Alboran I.M., Gandarillas A. Endogenous Myc controls mammalian epidermal cell size, hyperproliferation, endoreplication and stem cell amplification. J. Cell Sci. 2005, 118:1693-1704.
67. Tumaneng K., Russell R.C., Guan K.L. Organ size control by Hippo and TOR pathways. Curr. Biol. 2012, 22:R368-R379.
68. Tumaneng K., Schlegelmilch K., Russell R.C., Yimlamai D., Basnet H., Mahadevan N., et al. YAP mediates crosstalk between the Hippo and PI(3)K-TOR pathways by suppressing PTEN via miR-29. Nat. Cell Biol. 2012, 14:1322-1329.
69. Trendelenburg A.U., Meyer A., Rohner D., Boyle J., Hatakeyama S., Glass D.J. Myostatin reduces Akt/TORC1/p70S6K signaling, inhibiting myoblast differentiation and myotube size. Am. J. Physiol. 2009, 296C:1258-1270.
70. Andang M., Hjerling-Leffler J., Moliner A., Lundgren T.K., Castelo-Branco G., Nanou E., et al. Histone H2AX-dependent GABA(A) receptor regulation of stem cell proliferation. Nature 2008, 451:460-464.
71. Abdelhady S., Kitambi S.S., Lundin V., Aufschnaiter R., Sekyrova P., Sinha I., et al. Erg channel is critical in controlling cell volume during cell cycle in embryonic stem cells. PLOS ONE 2013, 8:e72409.
72. Song Y., Lu B. Regulation of cell growth by Notch signaling and its differential requirement in normal vs. tumor-forming stem cells in Drosophila. Genes Dev. 2011, 25:2644-2658.
73. Demidenko Z.N., Blagosklonny M.V. Growth stimulation leads to cellular senescence when the cell cycle is blocked. Cell Cycle 2008, 7:3355-3361.