Quaternary Structure Analyses of an Essential Oligomeric Enzyme

Methods in Enzymology

Volumn 562, Issue , 2015, Pages 205-223

  Soares Da Costa, Tatiana P ^a   Christensen, Janni B ^a   Desbois, Sebastien ^a   Gordon, Shane E ^a   Gupta, Ruchi ^a   Hogan, Campbell J ^a   Nelson, Tao G ^a   Downton, Matthew T ^b   Gardhi, Chamodi K ^a   Abbott, Belinda M ^a   Wagner, John ^b   Panjikar, Santosh ^c,d   Perugini, Matthew A ^a  

^a LA TROBE UNIVERSITY   (Australia)

^b IBM Australia   (Australia)

^c AUSTRALIAN SYNCHROTRON   (Australia)

^d MONASH UNIVERSITY   (Australia)

Author keywords

Analytical ultracentrifugation; Dihydrodipicolinate synthase; Molecular dynamics simulations; Oligomer; Quaternary structure; Sedimentation equilibrium; Sedimentation velocity; Self association; Small angle X ray scattering; X ray crystallography

Indexed keywords

BACTERIAL ENZYME; DIHYDRODIPICOLINATE SYNTHASE; OLIGOMERIC ENZYME; STAPHYLOCOCCUS AUREUS DIHYDRODIPICOLINATE SYNTHASE; SYNTHETASE; TETRAMER; UNCLASSIFIED DRUG; VEGETABLE PROTEIN; 4-HYDROXY-TETRAHYDRODIPICOLINATE SYNTHASE; BACTERIAL PROTEIN; HYDROLYASE; PROTEIN SUBUNIT;

CATALYSIS; CRYSTALLOGRAPHY; ENZYME ACTIVE SITE; ENZYME KINETICS; IN VITRO STUDY; MOLECULAR DYNAMICS; MUTAGENESIS; NONHUMAN; OUTCOME ASSESSMENT; PROTEIN QUATERNARY STRUCTURE; PROTEIN STRUCTURE; STRUCTURE ANALYSIS; ULTRACENTRIFUGATION; X RAY CRYSTALLOGRAPHY; CHEMISTRY; ISOLATION AND PURIFICATION; KINETICS; MOLECULAR EVOLUTION; PROTEIN MULTIMERIZATION; PROTEIN SUBUNIT; SMALL ANGLE SCATTERING; X RAY DIFFRACTION;

BACTERIAL PROTEINS; EVOLUTION, MOLECULAR; HYDRO-LYASES; KINETICS; MOLECULAR DYNAMICS SIMULATION; PLANT PROTEINS; PROTEIN MULTIMERIZATION; PROTEIN STRUCTURE, QUATERNARY; PROTEIN SUBUNITS; SCATTERING, SMALL ANGLE; ULTRACENTRIFUGATION; X-RAY DIFFRACTION;

EID: 84948582981     PISSN: 00766879     EISSN: 15577988     Source Type: Book Series    
DOI: 10.1016/bs.mie.2015.06.020     Document Type: Chapter

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