Metabolism and elimination of methyl, iso- and n-butyl paraben in human urine after single oral dosage

Archives of Toxicology

Volumn 90, Issue 11, 2016, Pages 2699-2709

  Moos, Rebecca K ^a   Angerer, Jürgen ^a   Dierkes, Georg ^a   Brüning, Thomas ^a   Koch, Holger M ^a  

^a RUHR UNIVERSITY BOCHUM   (Germany)

Author keywords

Human biomonitoring; Human metabolism; Parabens; Urinary metabolites

Indexed keywords

4 HYDROXYBENZOIC 2,3,5,6 DEUTERIUM 4 ACID; 4 HYDROXYBENZOIC ACID; 4 HYDROXYHIPPURIC ACID; ALKYL GROUP; AROMATIC COMPOUND; BENZOIC ACID DERIVATIVE; BIOLOGICAL MARKER; BUTYL PARABEN; DEUTERIUM; HIPPURIC ACID DERIVATIVE; HYDROXYL GROUP; ISO BUTYL 4 HYDROXYBENZOATE 2,3,5,6 DEUTERIUM 4; ISO BUTYL PARABEN; METHYL 4 HYDROXYBENZOATE 2,3,4,5,6 DEUTERIUM 4; METHYL PARABEN; N BUTYL 4 HYDROXYBENZOATE 2,3,5,6 DEUTERIUM 4; PRESERVATIVE; UNCLASSIFIED DRUG; 4 HYDROXYBENZOIC ACID ESTER; 4-HYDROXYBENZOIC ACID; 4-HYDROXYHIPPURIC ACID; ENDOCRINE DISRUPTOR; FOOD PRESERVATIVE; ISOBUTYLPARABEN;

ADULT; ARTICLE; BIOLOGICAL MONITORING; CHEMICAL MODIFICATION; CONJUGATION; CONTROLLED STUDY; DRUG ELIMINATION; DRUG EXCRETION; DRUG HYDROXYLATION; DRUG METABOLISM; DRUG URINE LEVEL; EXPOSURE; FEMALE; HUMAN; HUMAN EXPERIMENT; ISOTOPE LABELING; MALE; MAXIMUM PLASMA CONCENTRATION; METABOLITE; NORMAL HUMAN; OXIDATION; PRIORITY JOURNAL; RISK ASSESSMENT; SINGLE DRUG DOSE; TIME TO MAXIMUM PLASMA CONCENTRATION; URINARY EXCRETION; URINE; URINE SAMPLING; ADVERSE EFFECTS; BIOTRANSFORMATION; CHEMISTRY; COMPARATIVE STUDY; ENVIRONMENTAL EXPOSURE; ENVIRONMENTAL MONITORING; GERMANY; HYDROXYLATION; METABOLISM; OXIDATION REDUCTION REACTION; STEREOISOMERISM; TOXICOKINETICS;

ADULT; BIOMARKERS; BIOTRANSFORMATION; DEUTERIUM; ENDOCRINE DISRUPTORS; ENVIRONMENTAL EXPOSURE; ENVIRONMENTAL MONITORING; FOOD PRESERVATIVES; GERMANY; HIPPURATES; HUMANS; HYDROXYLATION; OXIDATION-REDUCTION; PARABENS; PRESERVATIVES, PHARMACEUTICAL; RENAL ELIMINATION; STEREOISOMERISM; TOXICOKINETICS;

EID: 84948175994     PISSN: 03405761     EISSN: 14320738     Source Type: Journal    
DOI: 10.1007/s00204-015-1636-0     Document Type: Article

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