Amino acid variation in HLA class II proteins is a major determinant of humoral response to common viruses

American Journal of Human Genetics

Volumn 97, Issue 5, 2015, Pages 738-743

  Hammer, Christian ^a,b,c   Begemann, Martin ^c   McLaren, Paul J ^a,b   Bartha, István ^a,b   Michel, Angelika ^d   Klose, Beate ^e   Schmitt, Corinna ^e   Waterboer, Tim ^d   Pawlita, Michael ^d   Schulz, Thomas F ^e   Ehrenreich, Hannelore ^c,f   Fellay, Jacques ^a,b  

^a EPFL   (Switzerland)

^b SWISS INSTITUTE OF BIOINFORMATICS   (Switzerland)

^c MAX PLANCK INSTITUTE OF EXPERIMENTAL MEDICINE   (Germany)

^d GERMAN CANCER RESEARCH CENTER DKFZ   (Germany)

^e HANNOVER MEDICAL SCHOOL   (Germany)

^f Deutsche Forschungsgemeinschaft   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

AMINO ACID; HLA ANTIGEN CLASS 2; HLA DQB1 ANTIGEN; IMMUNOGLOBULIN G;

ALLELE; ARTICLE; AUTOIMMUNE DISEASE; CHROMOSOME 6; EPSTEIN BARR VIRUS; GENE LINKAGE DISEQUILIBRIUM; GENETIC ASSOCIATION; HAPLOTYPE; HUMAN; HUMORAL IMMUNITY; INFLUENZA A VIRUS; JC VIRUS; MAJOR HISTOCOMPATIBILITY COMPLEX; MERKEL CELL POLYOMAVIRUS; NONHUMAN; PHENOTYPE; PRIORITY JOURNAL; SINGLE NUCLEOTIDE POLYMORPHISM; ADULT; BLOOD; CASE CONTROL STUDY; CHEMISTRY; COMPARATIVE STUDY; FEMALE; FOLLOW UP; GENETICS; GENOME-WIDE ASSOCIATION STUDY; IMMUNOCOMPROMISED PATIENT; IMMUNOLOGY; MALE; PATHOLOGY; PROGNOSIS; PROTEIN CONFORMATION; SCHIZOPHRENIA; VIROLOGY; VIRUS; VIRUS INFECTION;

ADULT; AUTOIMMUNE DISEASES; CASE-CONTROL STUDIES; FEMALE; FOLLOW-UP STUDIES; GENOME-WIDE ASSOCIATION STUDY; HISTOCOMPATIBILITY ANTIGENS CLASS II; HUMANS; IMMUNITY, HUMORAL; IMMUNOCOMPROMISED HOST; IMMUNOGLOBULIN G; MALE; POLYMORPHISM, SINGLE NUCLEOTIDE; PROGNOSIS; PROTEIN CONFORMATION; SCHIZOPHRENIA; VIRUS DISEASES; VIRUSES;

EID: 84947939931     PISSN: 00029297     EISSN: 15376605     Source Type: Journal    
DOI: 10.1016/j.ajhg.2015.09.008     Document Type: Article

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